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Review

Nucleoside analogues in the treatment of haematological malignancies

Pages 929-943 | Published online: 24 Feb 2005

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Saeedeh Mirzaee, Staffan Eriksson & Freidoun Albertioni. (2010) Differences in cytosolic and mitochondrial 5′-nucleotidase and deoxynucleoside kinase activities in Sprague–Dawley rat and CD-1 mouse tissues: Implication for the toxicity of nucleoside analogs in animal models. Toxicology 267:1-3, pages 159-164.
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Tadeusz Robak, Anna Korycka, Ewa Lech-Maranda & Pawel Robak. (2009) Current Status of Older and New Purine Nucleoside Analogues in the Treatment of Lymphoproliferative Diseases. Molecules 14:3, pages 1183-1226.
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B Ewald, D Sampath & W Plunkett. (2008) Nucleoside analogs: molecular mechanisms signaling cell death. Oncogene 27:50, pages 6522-6537.
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Brett C. Bookser & Nicholas B. Raffaele. (2008) High-Throughput Synthesis of HepDirect Prodrugs of Nucleoside Monophosphates. Journal of Combinatorial Chemistry 10:4, pages 567-572.
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S Henrich & R I Christopherson. (2007) Multiple forms of nuclear p53 formed in human Raji and MEC1 cells treated with fludarabine. Leukemia 22:3, pages 657-660.
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Agus Darwanto, Lynda Ngo & Lawrence C. Sowers. 2008. 153 182 .
Taichun Qin, Emile M. Youssef, Jaroslav Jelinek, Rong Chen, Allen S. Yang, Guillermo Garcia-Manero & Jean-Pierre J. Issa. (2007) Effect of Cytarabine and Decitabine in Combination in Human Leukemic Cell Lines. Clinical Cancer Research 13:14, pages 4225-4232.
Crossref
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Crossref
F. Morschhauser, S. Depil, E. Jourdan, M. Wetterwald, R. Bouabdallah, G. Marit, P. Solal-Céligny, C. Sebban, B. Coiffier, N. Chouaki, F. Bauters & C. Dumontet. (2007) Phase II study of gemcitabine–dexamethasone with or without cisplatin in relapsed or refractory mantle cell lymphoma. Annals of Oncology 18:2, pages 370-375.
Crossref
Brett C. Bookser & Nicholas B. Raffaele. (2006) High-Throughput Five Minute Microwave Accelerated Glycosylation Approach to the Synthesis of Nucleoside Libraries. The Journal of Organic Chemistry 72:1, pages 173-179.
Crossref
Avenelle I. Turner, Kevin A. Hahn, Anthony Rusk, Ranee M. Gamblin, Sallie B. Cosgrove, Kelly Griffice & Chand Khanna. (2008) Single Agent Gemcitabine Chemotherapy in Dogs with Spontaneously Occurring Lymphoma. Journal of Veterinary Internal Medicine 20:6, pages 1384-1388.
Crossref
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Crossref
H Pelicano, J S Carew, T J McQueen, M Andreeff, W Plunkett, M J Keating & P Huang. (2006) Targeting Hsp90 by 17-AAG in leukemia cells: mechanisms for synergistic and antagonistic drug combinations with arsenic trioxide and Ara-C. Leukemia 20:4, pages 610-619.
Crossref
Dorothy B. Colagiovanni, Daniel W. Drolet, Larry Dihel, Dennis J. Meyer, Karen Hart & Julie Wolf. (2016) Safety Assessment of 4′-Thio- β - d -Arabinofuranosylcytosine in the Beagle Dog Suggests a Drug-Induced Centrally Mediated Effect on the Hypothalamic-Pituitary-Adrenal Axis . International Journal of Toxicology 25:2, pages 119-126.
Crossref
A. Marczak, B. Bukowska, M. Koczmara & Z. Jóźwiak. (2013) The influence of 2‐chlorodeoxyadenosine (2‐CdA) on the adenine energy charge and glutathione content of human erythrocytes. Cell Biology International 28:12, pages 949-954.
Crossref
F FOSS. (2004) Nucleoside analogs and antimetabolite therapies for myelodysplastic syndrome. Best Practice & Research Clinical Haematology 17:4, pages 573-584.
Crossref
A. Marczak, D. Łubgan, T. Robak & Z. Jóźwiak. (2004) Influence of 2-chlorodeoxyadenosine (cladribine) on human erythrocytes. The International Journal of Biochemistry & Cell Biology 36:8, pages 1645-1654.
Crossref
L Polito, A Bolognesi, P L Tazzari, V Farini, C Lubelli, P L Zinzani, F Ricci & F Stirpe. (2004) The conjugate Rituximab/saporin-S6 completely inhibits clonogenic growth of CD20-expressing cells and produces a synergistic toxic effect with Fludarabine. Leukemia 18:7, pages 1215-1222.
Crossref
M Pastor-Anglada, M Molina-Arcas, F J Casado, B Bellosillo, D Colomer & J Gil. (2004) Nucleoside transporters in chronic lymphocytic leukaemia. Leukemia 18:3, pages 385-393.
Crossref
Donatella Aldinucci, Dalisa Poletto, Debora Lorenzon, Paola Nanni, Massimo Degan, Karin Olivo, Barbara Rapanà, Antonio Pinto & Valter Gattei. (2004) CD26 Expression Correlates with a Reduced Sensitivity to 2′-Deoxycoformycin-Induced Growth Inhibition and Apoptosis in T-Cell Leukemia/Lymphomas. Clinical Cancer Research 10:2, pages 508-520.
Crossref
Deepa Sampath, V Ashutosh Rao & William Plunkett. (2003) Mechanisms of apoptosis induction by nucleoside analogs. Oncogene 22:56, pages 9063-9074.
Crossref
Rodrigo Rico‐Gómez, Angel Rodríguez‐González, Josefa Ríos‐Ruíz, Francisco Nájera & J. Manuel López‐Romero. (2003) Synthesis of Theophylline and 6‐Thiotheophylline 7‐Ribosyl Nucleosides. European Journal of Organic Chemistry 2003:20, pages 4023-4032.
Crossref
Daekyu Sun, Rheanna Urrabaz, Christoph Buzello & Myhanh Nguyen. (2002) Induction of DNA Ligase I by 1-β-d-Arabinosylcytosine and Aphidicolin in MiaPaCa Human Pancreatic Cancer Cells. Experimental Cell Research 280:1, pages 90-96.
Crossref
Francis J. Giles, Armand Keating, Anthony H. Goldstone, Irit Avivi, Cheryl L. Willman & Hagop M. Kantarjian. (2002) Acute Myeloid Leukemia. Hematology 2002:1, pages 73-110.
Crossref

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