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Drug Evaluations

Combination therapy for hypertension: focus on high-dose olmesartan medoxomil (40 mg) plus hydrochlorothiazide

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Pages 2231-2242 | Published online: 15 Aug 2010

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Peter Bramlage, Claudia Zemmrich, Reinhard Ketelhut, Wolf-Peter Wolf, Eva-Maria Fronk & Roland E Schmieder. (2013) Safety, tolerability, and efficacy of a fixed-dose combination of olmesartan 40 mg and hydrochlorothiazide 12.5/25 mg in daily practice. Vascular Health and Risk Management 9, pages 475-483.
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Krzysztof Narkiewicz. (2012) Angiotensin II receptor blocker combinations: From guidelines to clinical practice. Blood Pressure 21:2, pages 73-81.
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Articles from other publishers (6)

Yumi Nishiya, Eiko Suzuki, Tomoko Ishizuka, Miho Kazui, Hidetaka Sakurai & Daisuke Nakai. (2020) Identification of non-P450 enzymes involved in the metabolism of new drugs: Their significance in drug interaction evaluation and prodrug disposition. Drug Metabolism and Pharmacokinetics 35:1, pages 45-55.
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Massimo Volpe, Caterina Santolamazza, Vittoria Mastromarino, Roberta Coluccia, Allegra Battistoni & Giuliano Tocci. (2017) Monotherapy and Dual Combination Therapies Based on Olmesartan: A Comprehensive Strategy to Improve Blood Pressure Control. High Blood Pressure & Cardiovascular Prevention 24:3, pages 243-253.
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Tomoko Ishizuka, Veronika Rozehnal, Thomas Fischer, Ayako Kato, Seiko Endo, Yasushi Yoshigae, Atsushi Kurihara & Takashi Izumi. (2013) Interindividual Variability of Carboxymethylenebutenolidase Homolog, a Novel Olmesartan Medoxomil Hydrolase, in the Human Liver and Intestine. Drug Metabolism and Disposition 41:5, pages 1156-1162.
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Hiromichi Suzuki, Yukio Shimada & Kenji Fujiwara. (2012) Combination therapy with losartan/hydrochlorothiazide for blood pressure reduction and goal attainment in a real-world clinical setting in Japan. Therapeutic Advances in Cardiovascular Disease 6:6, pages 237-244.
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Tomoko Ishizuka, Izumi Fujimori, Atsuko Nishida, Hidetaka Sakurai, Yasushi Yoshigae, Kaori Nakahara, Atsushi Kurihara, Toshihiko Ikeda & Takashi Izumi. (2012) Paraoxonase 1 as a Major Bioactivating Hydrolase for Olmesartan Medoxomil in Human Blood Circulation: Molecular Identification and Contribution to Plasma Metabolism. Drug Metabolism and Disposition 40:2, pages 374-380.
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. (2011) Current World Literature. Current Opinion in Nephrology & Hypertension 20:5, pages 561-571.
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