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Original Research

Prolonged-release oxycodone/naloxone in the treatment of neuropathic pain – results from a large observational study

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Pages 299-311 | Published online: 06 Jan 2012

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Read on this site (10)

Wojciech Leppert, Renata Zajaczkowska & Jerzy Wordliczek. (2019) The role of oxycodone/naloxone in the management of patients with pain and opioid-induced constipation. Expert Opinion on Pharmacotherapy 20:5, pages 511-522.
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Gineke Koopmans-Klein, Joeri Van Op den Bosch, Yvonne van Megen, Hans Prenen, Frank Huygen & Isabelle Mancini. (2017) Prolonged release oxycodone and naloxone treatment counteracts opioid-induced constipation in patients with severe pain compared to previous analgesic treatment. Current Medical Research and Opinion 33:12, pages 2217-2227.
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Wojciech Leppert. (2015) Emerging therapies for patients with symptoms of opioid-induced bowel dysfunction. Drug Design, Development and Therapy 9, pages 2215-2231.
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Fabio Guerriero, Niccolo Maurizi, Matthew Francis, Carmelo Sgarlata, Giovanni Ricevuti, Mariangela Rondanelli, Simone Perna & Marco Rollone. (2015) Is oxycodone/naloxone effective and safe in managing chronic pain of a fragile elderly patient with multiple skin ulcers of the lower limbs? A case report. Clinical Interventions in Aging 10, pages 1283-1287.
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Thomas Nolte, Ulf Schutter & Oliver Loewenstein. (2014) Cancer pain therapy with a fixed combination of prolonged-release oxycodone/naloxone: results from a non-interventional study. Pragmatic and Observational Research 5, pages 1-13.
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Gineke Koopmans, Karen Simpson, Javier De Andrés, Eberhard Albert Lux, Michel Wagemans & Yvonne Van Megen. (2014) Fixed ratio (2:1) prolonged-release oxycodone/naloxone combination improves bowel function in patients with moderate-to-severe pain and opioid-induced constipation refractory to at least two classes of laxatives. Current Medical Research and Opinion 30:11, pages 2389-2396.
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M. Lazzari, A. F. Sabato, C. Caldarulo, M. Casali, P. Gafforio, C. Marcassa & F. Leonardis. (2014) Effectiveness and tolerability of low-dose oral oxycodone/naloxone added to anticonvulsant therapy for noncancer neuropathic pain: an observational analysis. Current Medical Research and Opinion 30:4, pages 555-564.
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Michael J Brennan. (2013) Update on prescription extended-release opioids and appropriate patient selection. Journal of Multidisciplinary Healthcare 6, pages 265-280.
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Mellar Davis, Harold W Goforth & Pam Gamier. (2013) Oxycodone combined with opioid receptor antagonists: efficacy and safety. Expert Opinion on Drug Safety 12:3, pages 389-402.
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Sebastiano Mercadante & Antonello Giarratano. (2013) Combined oral prolonged-release oxycodone and naloxone in chronic pain management. Expert Opinion on Investigational Drugs 22:1, pages 161-166.
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Articles from other publishers (15)

Hong-Yang Chen, Zi-Ning Wang, Wei-Yi Zhang & Tao Zhu. (2022) Advances in the clinical application of oxycodone in the perioperative period. World Journal of Clinical Cases 10:16, pages 5156-5164.
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Lorella Pasquinucci, Carmela Parenti, Zafiroula Georgoussi, Lorena Reina, Emilia Tomarchio & Rita Turnaturi. (2021) LP1 and LP2: Dual-Target MOPr/DOPr Ligands as Drug Candidates for Persistent Pain Relief. Molecules 26:14, pages 4168.
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Bart J. Morlion, Stefan A. Mueller‐Lissner, Renato Vellucci, Wojciech Leppert, Benoît C. Coffin, Sara L. Dickerson & Tony O'Brien. (2017) Oral Prolonged‐Release Oxycodone/Naloxone for Managing Pain and Opioid‐Induced Constipation: A Review of the Evidence. Pain Practice 18:5, pages 647-665.
Crossref
. 2018. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin 447 696 .
Esther S. Kim. (2017) Oxycodone/Naloxone Prolonged Release: A Review in Severe Chronic Pain. Clinical Drug Investigation 37:12, pages 1191-1201.
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Sevasti Gaspari, Valeria Cogliani, Lefteris Manouras, Ethan M Anderson, Vasiliki Mitsi, Kleopatra Avrampou, Fiona B Carr & Venetia Zachariou. (2017) RGS9-2 Modulates Responses to Oxycodone in Pain-Free and Chronic Pain States. Neuropsychopharmacology 42:7, pages 1548-1556.
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Magdalena Kocot-KępskaRenata ZajączkowskaAnna Przeklasa-MuszyńskaJan Dobrogowski. (2017) The role of oxycodone/naloxone in pain management. BÓL 17:4, pages 26-40.
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Geoff P. Bostick, Cory Toth, Eloise C.J. Carr, Larry W. Stitt, Patricia Morley-Forster, Alexander J. Clark, Mary Lynch, Allan Gordon, Howard Nathan, Catherine Smyth, Mark A. Ware & Dwight E. Moulin. (2015) Physical Functioning and Opioid use in Patients with Neuropathic Pain. Pain Medicine 16:7, pages 1361-1368.
Crossref
. 2015. Arzneimitteltherapie in der Palliativmedizin. Arzneimitteltherapie in der Palliativmedizin 417 651 .
Michael Zimmermann & Ute Richarz. (2014) End-of-Dose Pain in Chronic Pain: Does it Vary with the Use of Different Long-Acting Opioids?. Pain Practice 14:8, pages 757-769.
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Anne Z. DePriest & Katie Miller. (2014) Oxycodone/Naloxone: Role in Chronic Pain Management, Opioid-Induced Constipation, and Abuse Deterrence. Pain and Therapy 3:1, pages 1-15.
Crossref
Sabine Hesselbarth, Oliver Löwenstein & Thomas Cegla. (2014) Effects of prolonged-release oxycodone/naloxone on pain control, bowel function and quality of life: A prospective observational study. Scandinavian Journal of Pain 5:2, pages 75-81.
Crossref
Celeste B. Burness & Gillian M. Keating. (2014) Oxycodone/Naloxone Prolonged-Release: A Review of Its Use in the Management of Chronic Pain While Counteracting Opioid-Induced Constipation. Drugs 74:3, pages 353-375.
Crossref
Luca Miceli, Rym Bednarova, Massimo Sandri, Alessandro Rizzardo & Giorgio Della Rocca. (2013) Use of Opioids for Pain Relief While Driving: When The Patient Meets The Police. Pain Practice 13:4, pages 345-345.
Crossref
Antonio Gatti, Manuela Casali, Marzia Lazzari, Giuseppe Tufaro, Paolo Gafforio, Claudia Silvestri, Claudio Marcassa & Alessandro F. Sabato. (2012) Prolonged-Release Oxycodone/Naloxone in Nonmalignant Pain: Single-Center Study in Patients with Constipation. Advances in Therapy 30:1, pages 41-59.
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