808
Views
81
CrossRef citations to date
0
Altmetric
Reviews

Fixed-combination intraocular pressure-lowering therapy for glaucoma and ocular hypertension: advantages in clinical practice

, MD PhD DSc, , MD & , MD

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (16)

Francesco Oddone, Vincenzo Scorcia, Michele Iester, Dario Sisto, Stefano De Cilla, Paolo Bettin, Carlo Cagini, Michele Figus, Giorgio Marchini, Luca Rossetti, Gemma Rossi, Tommaso Salgarello, Gian Luca Scuderi & Giovanni Staurenghi. (2022) Treatment of Open-Angle Glaucoma and Ocular Hypertension with the Fixed-Dose Combination of Preservative-Free Tafluprost/Timolol: Clinical Outcomes from Ophthalmology Clinics in Italy. Clinical Ophthalmology 16, pages 1707-1719.
Read now
Gábor Holló, James Kirwan, Fernando Lopez-Lopez, Marina Zimina, Claudia Fassari & Francesco Oddone. (2022) A comparison of country-level data from the VISIONARY study examining treatment outcomes with preservative-free tafluprost/timolol fixed-dose combination therapy. Current Medical Research and Opinion 38:7, pages 1189-1201.
Read now
Anastasios G. Konstas, Antoine Labbé, Andreas Katsanos, Frances Meier-Gibbons, Murat Irkec, Konstadinos G. Boboridis, Gábor Holló, Julián García-Feijoo, Gordon N. Dutton & Christophe Baudouin. (2021) The treatment of glaucoma using topical preservative-free agents: an evaluation of safety and tolerability. Expert Opinion on Drug Safety 20:4, pages 453-466.
Read now
Wesam Shamseldin Shalaby, Vikram Shankar, Reza Razeghinejad & L. Jay Katz. (2020) Current and new pharmacotherapeutic approaches for glaucoma. Expert Opinion on Pharmacotherapy 21:16, pages 2027-2040.
Read now
Lindsay Machen, Reza Razeghinejad & Jonathan S. Myers. (2020) Fixed-combination topical anti-hypertensive ophthalmic agents. Expert Opinion on Pharmacotherapy 21:10, pages 1269-1282.
Read now
Alessio Nocentini & Claudiu T. Supuran. (2019) Adrenergic agonists and antagonists as antiglaucoma agents: a literature and patent review (2013–2019). Expert Opinion on Therapeutic Patents 29:10, pages 805-815.
Read now
Vassilios Kozobolis, Aristeidis Konstantinidis, Haris Sideroudi & Miguel Teus. (2018) Efficacy of the travoprost/timolol fixed combination versus the concomitant use of travoprost 0.004% and timolol 0.1% gel formulation. Clinical Ophthalmology 12, pages 2393-2398.
Read now
Anastasios-Georgios Konstas, Andreas Katsanos, Georgios P. Athanasopoulos, Irini C. Voudouragkaki, Evangelia S. Panagiotou, Eirini Pagkalidou, Anna-Bettina Haidich, Dimitrios A. Giannoulis, Eleni Spathi, Theodoros Giannopoulos & L. Jay Katz. (2018) Preservative-free tafluprost/timolol fixed combination: comparative 24-h efficacy administered morning or evening in open-angle glaucoma patients. Expert Opinion on Pharmacotherapy 19:18, pages 1981-1988.
Read now
Tadashi Nakano, Shiro Mizoue, Nobuo Fuse, Aiko Iwase, Shun Matsumoto & Keiji Yoshikawa. (2017) Fixed combination of travoprost and timolol maleate reduces intraocular pressure in Japanese patients with primary open-angle glaucoma or ocular hypertension: analysis by prostaglandin analogue. Clinical Ophthalmology 11, pages 55-61.
Read now
Anastasios G. P. Konstas & Gabor Holló. (2016) Preservative-free tafluprost/timolol fixed combination: a new opportunity in the treatment of glaucoma. Expert Opinion on Pharmacotherapy 17:9, pages 1271-1283.
Read now
Gábor Holló, Andreas Katsanos & Anastasios GP Konstas. (2015) Management of exfoliative glaucoma: challenges and solutions. Clinical Ophthalmology 9, pages 907-919.
Read now
Yuan Fang, Zhihong Ling & Xinghuai Sun. (2015) Fixed-combination treatments for intraocular hypertension in Chinese patients – focus on bimatoprost-timolol. Drug Design, Development and Therapy 9, pages 2617-2625.
Read now
Gábor Holló & Andreas Katsanos. (2015) Safety and tolerability of the tafluprost/timolol fixed combination for the treatment of glaucoma. Expert Opinion on Drug Safety 14:4, pages 609-617.
Read now
Sky K Chew, Simon E Skalicky & Ivan Goldberg. (2014) Brinzolamide plus brimonidine for the treatment of glaucoma: an update. Expert Opinion on Pharmacotherapy 15:16, pages 2461-2471.
Read now

Articles from other publishers (65)

Rei Sakata, Shiro Mizoue, Keiji Yoshikawa, Misato Adachi, Shinji Ohkubo, Naoki Hamada, Tomoko Naito, Tomoyuki Muramatsu, Takeshi Hara, Ryo Asato & Makoto Aihara. (2023) Additive effects of brimonidine tartrate 0.1%/brinzolamide 1% fixed-dose combination in prostaglandin analog-treated Japanese glaucoma patients. Japanese Journal of Ophthalmology 67:6, pages 668-677.
Crossref
V. V. Neroev, S. Yu. Petrov, A. N. Zhuravleva, O. M. Filippova, O. M. Kalinina, L. V. Yakubova, S. M. Kosakyan & L. V. Vasilenkova. (2023) Efficiency and safety of the fixed latanoprost/ dorzolamide combination in open-angle glaucoma hypotensive treatment. Russian Ophthalmological Journal 16:3, pages 60-68.
Crossref
Masaru Inatani, Yusuke Orii, Kentaro Iwasaki, Shogo Arimura, Hiromi Sunagawa, Minako Shiokawa, Kenji Inoue, Takuto Sakono, Takato Sakono, Rika Kuwamura, Akiko Yoshida, Junko Oi, Yasuaki Kuwayama, Kiyoshi Kano, Noriaki Kido, Akiko Matsuyama, Mineo Ozaki, Hideki Abe, Chizuru Inoue, Satoko Nakagawa, Kunihiro Musashi, Akiyasu Kanamori, Jinhee Lee, Shinichiro Otani, Ryota Aoki, Hirotaka Tanabe, Shunsuke Nakakura, Katsuyoshi Suzuki, Takeshi Sagara, Yoshiaki Saito, Motoyasu Sameshima, Mai Urahashi, Fumika Watanabe-Kitamura, Toshihiro Inoue, Fumie Kagaya, Yusuke Murai, Sotaro Mori, Kaori Ueda, Takuji Kurimoto, Yuko Yamada-Nakanishi, Makoto Nakamura, Takehiro Yamashita, Sosuke Ishiyama, Shinichi Manabe, Keiko Takaki, Ken Hayashi, Akiko Ishida, Aika Tsutsui, Kaoru Manabe & Masaki Tanito. (2023) Randomized Multicenter Clinical Trial Comparing 0.1% Brimonidine/0.5% Timolol Versus 1% Dorzolamide/0.5% Timolol as Adjuncts to Prostaglandin Analogues: Aibeta Crossover Study. Advances in Therapy 40:9, pages 4074-4092.
Crossref
Ingeborg Stalmans, Kin Sheng Lim, Francesco Oddone, Marek Fichtl, Jose I. Belda, Anton Hommer, Guna Laganovska, Cédric Schweitzer, Bogomil Voykov, Tomasz Zarnowski & Gábor Holló. (2023) MERCURY-3: a randomized comparison of netarsudil/latanoprost and bimatoprost/timolol in open-angle glaucoma and ocular hypertension. Graefe's Archive for Clinical and Experimental Ophthalmology.
Crossref
S. Yu. Petrov, O. M. Kalinina, L. V. Yakubova, S. M. Kosakyan, L. V. Vasilenkova, O. M. Filippova, A. N. Zhuravleva & O. I. Markelova. (2023) Adjunctive antihypertensive therapy of primary glaucoma with a fixed combination drug of 1% brinzolamide and 0.5% timolol: efficacy and safety. Russian Ophthalmological Journal 16:2, pages 67-73.
Crossref
Najam A. Sharif. (2023) Identifying new drugs and targets to treat rapidly elevated intraocular pressure for angle closure and secondary glaucomas to curb visual impairment and prevent blindness. Experimental Eye Research 232, pages 109444.
Crossref
Srushti M. Tambe, Divya D. Jain, Chetan Hasmukh Mehta, Ashwini T.Usha Yogendra Nayak & Purnima D. Amin. (2023) Hot-melt extruded in situ gelling systems (MeltDrops Technology): Formulation development, in silico modelling and in vivo studies. European Journal of Pharmaceutics and Biopharmaceutics 188, pages 108-124.
Crossref
Najam A. Sharif. (2023) Recently Approved Drugs for Lowering and Controlling Intraocular Pressure to Reduce Vision Loss in Ocular Hypertensive and Glaucoma Patients. Pharmaceuticals 16:6, pages 791.
Crossref
Asahi Fujita, Yohei Hashimoto, Hiroki Matsui, Hideo Yasunaga & Makoto Aihara. (2023) Recent Trends in Treatment and Associated Costs of Primary Angle-Closure Glaucoma. Ophthalmology Glaucoma 6:3, pages 308-315.
Crossref
Kenji Nakamoto. (2023) Current Status and Limitations of Intraocular Pressure-lowering Therapy for Glaucoma緑内障に対する眼圧下降治療の現状と限界. Nihon Ika Daigaku Igakkai Zasshi 19:2, pages 156-163.
Crossref
Najam A. Sharif, Noriko Odani-Kawabata, Fenghe Lu & Leonard Pinchuk. (2023) FP and EP2 prostanoid receptor agonist drugs and aqueous humor outflow devices for treating ocular hypertension and glaucoma. Experimental Eye Research 229, pages 109415.
Crossref
Yoshiaki Kiuchi, Toshihiro Inoue, Nobuyuki Shoji, Makoto Nakamura, Masaki Tanito, Kenji Inoue, Kyoko Ishida, Yasuo Kurimoto, Yasuyuki Suzuki, Sinki Chin, Tomoko Naito, Megumi Honjo, Atsuya Miki, Takehiro Yamashita, Tadamichi Akagi, Yoko Ikeda, Shinichi Usui, Kazuko Omodaka, Shinji Ohokubo, Yasumasa Otori, Rumi Kawashima, Hiroshi Sakai, Akira Sawada, Hitomi Saito, Daisuke Shiba, Takuhei Shoji, Yasuhiro Shinmei, Tetsuya Togano, Kenji Nakamoto, Koji Nitta, Takeshi Hara, Tomomi Higashide, Katsuhiko Maruyama, Akira Matsuda, Shiro Mizoue, Satoshi Yoshimizu, Yu Yokoyama, Ryo Kawasaki & Kazuyuki Hirooka. (2023) The Japan Glaucoma Society guidelines for glaucoma 5th edition. Japanese Journal of Ophthalmology 67:2, pages 189-254.
Crossref
Najam A. Sharif. 2023. Translational Neuroimmunology, Volume 7. Translational Neuroimmunology, Volume 7 287 329 .
Daniel Laroche & Kara Rickford. 2022. Refractive Surgery - Types of Procedures, Risks, and Benefits. Refractive Surgery - Types of Procedures, Risks, and Benefits.
Xiaoyu Zhou, Xinyue Zhang, Dengming Zhou, Yang zhao & Xuanchu Duan. (2022) A Narrative Review of Ocular Surface Disease Related to Anti-Glaucomatous Medications. Ophthalmology and Therapy 11:5, pages 1681-1704.
Crossref
Francesco Oddone, James Kirwan, Fernando Lopez-Lopez, Marina Zimina, Claudia Fassari, Gábor Holló, Christoph Faschinger, Enping Chen, Gábor Holló, Gabor Nemeth, Gyorgy Bator, Alexis Tsorbatzoglou, Tamas Acs, Maria Ferencz, Zoltán Sohajda, Jeno Toth, Veronika Volner, Gábor Vogt, Zsolt Biro, Andrea Facskó, János Nemes, Andras Berta, Ilona Elek, Eugene Ng, Francesco Oddone, Gemma Rossi, Luca Rossetti, Michele Vetrugno, Michele Iester, Giorgio Marchini, Vincenzo Scorcia, Giovanni Staurenghi, Carlo Cagini, Tommaso Salgarello, Paolo Bettin, Michele Figus, Gian Luca Scuderi, Stefano De Cilla, Iveta Grundmane, Nora Linavska, Lasma Volksone, Guna Laganovska, Kristine Baumane, Hans Lemij, Kjell Gunnar Gundersen, Marina Zimina, Valery Erichev, Elmira Adbulaeva, Elena Karlova, Ekaterina Zakharova, Irina Panova, Boris Malyugin, Iñaki Rodríguez-Agirretxe, Fernando Lopez-Lopez, Antonio Moreno Valladares, Javier Benitez del Castillo, Rafael Gimenez, Maria Parrilla Vallejo, Jose Javier Garcia-Medina, Alfonso Anton Lopez, Sergio Torregrosa, Jorge Loscos, Miriam Kolko, Ejaz Ansari, David Broadway, Katharine Claridge, Simon Ruben, James Kirwan, Anca Nita, Michael Smith, Areeb Moosavi, Anthony J. W. King & Matthew Kinsella. (2022) Switching to Preservative-Free Tafluprost/Timolol Fixed-Dose Combination in the Treatment of Open-Angle Glaucoma or Ocular Hypertension: Subanalysis of Data from the VISIONARY Study According to Baseline Monotherapy Treatment. Advances in Therapy 39:8, pages 3501-3521.
Crossref
Jose J. Garcia-MedinaJavier Benitez-del-CastilloIñaki Rodríguez-AgirretxeFernando Lopez-LopezAntonio Moreno-ValladaresRafael Gimenez, Maria Parrilla Vallejo, Alfonso Anton lopez, Sergio Torregrosa & jorge loscos. (2022) Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: Results from the VISIONARY Study Population in Spain. Journal of Ocular Pharmacology and Therapeutics 38:3, pages 252-260.
Crossref
Irene Martínez-Alberquilla, Xavier Gasull, Patricia Pérez-Luna, Rubén Seco-Mera, Javier Ruiz-Alcocer & Almudena Crooke. (2022) Neutrophils and neutrophil extracellular trap components: Emerging biomarkers and therapeutic targets for age-related eye diseases. Ageing Research Reviews 74, pages 101553.
Crossref
Najam A. Sharif. (2022) Degeneration of retina-brain components and connections in glaucoma: Disease causation and treatment options for eyesight preservation. Current Research in Neurobiology 3, pages 100037.
Crossref
Najam A. Sharif. 2022. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics 251 288 .
Najam A. Sharif. 2022. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics. Handbook of Basic and Clinical Ocular Pharmacology and Therapeutics 309 316 .
Najam A. Sharif. (2021) Therapeutic Drugs and Devices for Tackling Ocular Hypertension and Glaucoma, and Need for Neuroprotection and Cytoprotective Therapies. Frontiers in Pharmacology 12.
Crossref
Jake E. Radell, Himanshu K. Sharma, Kelsey L. Auyeung, Megan E. Paul, Donna J. Gagliuso, Nisha Chadha, James C. Tsai & Janet B. Serle. (2021) Two-Year Experience With Latanoprostene Bunod in Clinical Practice. Journal of Glaucoma 30:9, pages 776-780.
Crossref
Srushti Tambe, Divya Jain & Purnima Amin. (2021) Simultaneous determination of dorzolamide and timolol by first-order derivative UV spectroscopy in simulated biological fluid for in vitro drug release testing. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 255, pages 119682.
Crossref
Ejaz Ansari, Jasna Pavicic-Astalos, Filis Ayan, Anthony J. King, Matthew Kinsella, Eugene Ng & Anca Nita. (2021) Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: UK and Ireland Results from the VISIONARY Study. Advances in Therapy 38:6, pages 2990-3002.
Crossref
Uday B. Kompella, Rachel R. Hartman & Madhoosudan A. Patil. (2021) Extraocular, periocular, and intraocular routes for sustained drug delivery for glaucoma. Progress in Retinal and Eye Research 82, pages 100901.
Crossref
Shikha Gupta, Anin Sethi, Suresh Yadav, Kishan Azmira, Abhishek Singh & Viney Gupta. (2021) Safety and efficacy of incisional goniotomy as an adjunct with phacoemulsification in primary angle-closure glaucoma. Journal of Cataract and Refractive Surgery 47:4, pages 504-511.
Crossref
Anastasios G. Konstas, Leopold Schmetterer, Andreas Katsanos, Cindy M. L. Hutnik, Gábor Holló, Luciano Quaranta, Miguel A. Teus, Hannu Uusitalo, Norbert Pfeiffer & L. Jay Katz. (2020) Dorzolamide/Timolol Fixed Combination: Learning from the Past and Looking Toward the Future. Advances in Therapy 38:1, pages 24-51.
Crossref
Prin Rojanapongpun & Visanee Tantisevi. 2021. Primary Angle Closure Glaucoma (PACG). Primary Angle Closure Glaucoma (PACG) 31 44 .
Najam A. Sharif. (2020) Discovery to Launch of Anti-allergy (Emadine; Patanol/Pataday/Pazeo) and Anti-glaucoma (Travatan; Simbrinza) Ocular Drugs, and Generation of Novel Pharmacological Tools Such as AL-8810. ACS Pharmacology & Translational Science 3:6, pages 1391-1421.
Crossref
Jacob W. Brubaker, Savak Teymoorian, Richard A. Lewis, Dale Usner, Hayley J. McKee, Nancy Ramirez, Casey C. Kopczynski & Theresa Heah. (2020) One Year of Netarsudil and Latanoprost Fixed-Dose Combination for Elevated Intraocular Pressure. Ophthalmology Glaucoma 3:5, pages 327-338.
Crossref
Assumpta Peral, Alejandro Martinez-Aguila, Cristina Pastrana, Fernando Huete-Toral, Carlos Carpena-Torres & Gonzalo Carracedo. (2020) Contact Lenses as Drug Delivery System for Glaucoma: A Review. Applied Sciences 10:15, pages 5151.
Crossref
Sanjay Asrani, Jason Bacharach, Edward Holland, Hayley McKee, Huan Sheng, Richard A. Lewis, Casey C. Kopczynski & Theresa Heah. (2020) Fixed-Dose Combination of Netarsudil and Latanoprost in Ocular Hypertension and Open-Angle Glaucoma: Pooled Efficacy/Safety Analysis of Phase 3 MERCURY-1 and -2. Advances in Therapy 37:4, pages 1620-1631.
Crossref
Francesco Oddone, Lucia Tanga, Péter Kóthy, Gábor Holló, Christoph Faschinger, Enping Chen, Gabor Holló, Gabor Nemeth, Gyorgy Bator, Alexis Tsorbatzoglou, Tamas Acs, Maria Ferencz, Zoltán Sohajda, Jeno Toth, Veronika Volner, Gabor Vogt, Zsolt Biro, Andrea Facskó, János Nemes, Andras Berta, Ilona Elek, Eugene Ng, Francesco Oddone, Gemma Rossi, Luca Rossetti, Michele Vetrugno, Michele Iester, Giorgio Marchini, Vincenzo Scorcia, Giovanni Staurenghi, Carlo Cagini, Tommaso Salgarello, Paolo Bettin, Michele Figus, Gian Luca Scuderi, Stefano De Cilla, Iveta Grundmane, Nora Linavska, Lasma Volksone, Guna Laganovska, Kristine Baumane, Hans Lemij, Kjell Gunnar Gundersen, Marina Zimina, Valery Erichev, Elena Karlova, Ekaterina Zakharova, Irina Panova, Boris Malyugin, Inaki Rodriguez Aguirrec, Fernando Lopez–Lopez, Antonio Moreno Valladares, Javier Benitez del Castillo, Rafael Gimenez, Maria Parrilla Vallejo, Jose Garcia Medina, Alfonso Anton Lopez, Sergio Torregrosa, Jorge Loscos, Miriam Kolko, Ejaz Ansari, David Broadway, Katharine Claridge, Simon Ruben, James Kirwan, Anca Nita, Micheal Smith, Areeb Moosavi, Anthony J. W. King & Matthew Kinsella. (2020) Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: The VISIONARY Study. Advances in Therapy 37:4, pages 1436-1451.
Crossref
Rubens BelfortJr.Jr., Jayter Silva Paula, Marcelo Jordão Lopes Silva, Mauricio Della Paolera, Thomas Kim, Michelle Y. Chen & Margot L. Goodkin. (2020) Fixed-combination Bimatoprost/Brimonidine/Timolol in Glaucoma: A Randomized, Masked, Controlled, Phase III Study Conducted in Brazil☆. Clinical Therapeutics 42:2, pages 263-275.
Crossref
Péter Kóthy & Gábor Holló. (2019) Real-life experience of using brinzolamide/brimonidine fixed drop combination in a tertiary glaucoma centre. International Ophthalmology 40:2, pages 377-383.
Crossref
Nikki A. Mehran, Sapna Sinha & Reza Razeghinejad. (2019) New glaucoma medications: latanoprostene bunod, netarsudil, and fixed combination netarsudil-latanoprost. Eye 34:1, pages 72-88.
Crossref
Najam A. Sharif. 2020. Drug Discovery and Evaluation: Methods in Clinical Pharmacology. Drug Discovery and Evaluation: Methods in Clinical Pharmacology 163 208 .
Florent Aptel, Norbert Pfeiffer, Stefanie Schmickler, Jonathan Clarke, Cosme Lavín-Dapena, Javier Moreno-Montañés, Tomasz Żarnowski, Adrienne Csutak, Tiia Jugaste, Lāsma Volksone, Yury S. Astakhov, Laurent Coupier, Jean-Philippe Nordmann & Ingeborg Stalmans. (2019) Noninferiority of Preservative-free Versus BAK-preserved Latanoprost-timolol Fixed Combination Eye Drops in Patients With Open-angle Glaucoma or Ocular Hypertension. Journal of Glaucoma 28:6, pages 498-506.
Crossref
Peter G Klimko & Najam A Sharif. (2018) Discovery, characterization and clinical utility of prostaglandin agonists for the treatment of glaucoma. British Journal of Pharmacology 176:8, pages 1051-1058.
Crossref
A. Arranz-Romera, B.M. Davis, I. Bravo-Osuna, S. Esteban-Pérez, I.T. Molina-Martínez, E. Shamsher, N. Ravindran, L. Guo, M.F. Cordeiro & R. Herrero-Vanrell. (2019) Simultaneous co-delivery of neuroprotective drugs from multi-loaded PLGA microspheres for the treatment of glaucoma. Journal of Controlled Release 297, pages 26-38.
Crossref
Najam A. Sharif. 2019. Drug Discovery and Evaluation: Methods in Clinical Pharmacology. Drug Discovery and Evaluation: Methods in Clinical Pharmacology 1 46 .
Reza Moosavi & Ejaz Ansari. (2018) Brinzolamide/Brimonidine Fixed Combination: Simplifying Glaucoma Treatment Regimens. Ophthalmology and Therapy 7:2, pages 397-403.
Crossref
Gilberto Spadoni, Annalida Bedini, Lucia Furiassi, Michele Mari, Marco Mor, Laura Scalvini, Alessio Lodola, Andrea Ghidini, Valeria Lucini, Silvana Dugnani, Francesco Scaglione, Daniele Piomelli, Kwang-Mook Jung, Claudiu T. Supuran, Laura Lucarini, Mariaconcetta Durante, Silvia Sgambellone, Emanuela Masini & Silvia Rivara. (2018) Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit. Journal of Medicinal Chemistry 61:17, pages 7902-7916.
Crossref
Alessio Nocentini, Mariangela Ceruso, Silvia Bua, Carrie L. Lomelino, Jacob T. Andring, Robert McKenna, Cecilia Lanzi, Silvia Sgambellone, Riccardo Pecori, Rosanna Matucci, Luca Filippi, Paola Gratteri, Fabrizio Carta, Emanuela Masini, Silvia Selleri & Claudiu T. Supuran. (2018) Discovery of β-Adrenergic Receptors Blocker–Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy. Journal of Medicinal Chemistry 61:12, pages 5380-5394.
Crossref
Francisco Gómez-Aguayo, José A. Paczka, Rubén Leñero-Córdova, Jesús Jiménez-Román, Jaime Davila-Villarreal, Curt Hartleben, Leopoldo Baiza-Durán, Oscar Olvera-Montaño, Francisco García-Velez & Patricia Muñoz-Villegas. (2018) A Phase III Randomized Clinical Trial of a 0.5% Timolol + 0.2% Brimonidine + 2.0% Dorzolamide Fixed Combination, Preservative-Free Ophthalmic Solution vs. 0.5% Timolol + 0.2% Brimonidine + 2.0% Dorzolamide Fixed Combination in Patients with Controlled Primary Open-Angle Glaucoma. Ophthalmology and Therapy 7:1, pages 145-156.
Crossref
Katsuyoshi Suzuki, Naomi Otsuka, Hiroko Hizaki, Masayo Hashimoto & Yasuaki Kuwayama. (2018) Multicenter, Randomized, Controlled Study Comparing Tafluprost/Timolol Fixed Combination with Latanoprost/Timolol Fixed Combination in Primary Open-Angle Glaucoma and Ocular Hypertension. Advances in Therapy 35:6, pages 796-808.
Crossref
Luca Agnifili, Rodolfo Mastropasqua, Vincenzo Fasanella, Lorenza Brescia, Barbara Scatena, Francesco Oddone & Leonardo Mastropasqua. (2018) Meibomian Gland Features and Conjunctival Goblet Cell Density in Glaucomatous Patients Controlled With Prostaglandin/Timolol Fixed Combinations: A Case Control, Cross-sectional Study. Journal of Glaucoma 27:4, pages 364-370.
Crossref
Najam A. Sharif. (2018) i Drugs and i Devices Discovery Research: Preclinical Assays, Techniques, and Animal Model Studies for Ocular Hypotensives and Neuroprotectants . Journal of Ocular Pharmacology and Therapeutics 34:1-2, pages 7-39.
Crossref
NajamA Sharif. (2018) Glaucomatous optic neuropathy treatment options: the promise of novel therapeutics, techniques and tools to help preserve vision. Neural Regeneration Research 13:7, pages 1145.
Crossref
Jacopo Allamprese, Michele Allamprese, Francesco Gelormini, Alessandro Rabiolo & Giuseppe Querques. (2018) DUO: an innovative multidrug delivery system. Therapeutic Advances in Ophthalmology 10, pages 251584141881206.
Crossref
Gábor Holló, Andreas Katsanos, Kostas G. Boboridis, Murat Irkec & Anastasios G. P. Konstas. (2017) Preservative-Free Prostaglandin Analogs and Prostaglandin/Timolol Fixed Combinations in the Treatment of Glaucoma: Efficacy, Safety and Potential Advantages. Drugs 78:1, pages 39-64.
Crossref
Makoto Aihara, Misato Adachi, Hiroshi Matsuo, Tetsuya Togano, Takeo Fukuchi & Noriyuki Sasaki. (2017) Additive effects and safety of fixed combination therapy with 1% brinzolamide and 0.5% timolol versus 1% dorzolamide and 0.5% timolol in prostaglandin-treated glaucoma patients. Acta Ophthalmologica 95:8, pages e720-e726.
Crossref
Susan Yee. (2017) Glaucoma Theraphy: Finding the Right Combination. Highlights of Ophthalmology 45:2ENG, pages 6-10.
Crossref
Howard S. Barnebey & Alan L. Robin. (2017) Adherence to Fixed-Combination Versus Unfixed Travoprost 0.004%/Timolol 0.5% for Glaucoma or Ocular Hypertension: A Randomized Trial. American Journal of Ophthalmology 176, pages 61-69.
Crossref
Vassileios Kozobolis, Georgios D. Panos, Aristeidis Konstantinidis & Georgios Labiris. (2016) Comparison of Dorzolamide/Timolol vs Brinzolamide/Brimonidine Fixed Combination Therapy in the Management of Primary Open-Angle Glaucoma. European Journal of Ophthalmology 27:2, pages 160-163.
Crossref
Ronan Conlon, Hady Saheb & Iqbal Ike K. Ahmed. (2017) Glaucoma treatment trends: a review. Canadian Journal of Ophthalmology 52:1, pages 114-124.
Crossref
Curt Hartleben, Juan Camilo Parra, Amy Batoosingh, Paula Bernstein & Margot Goodkin. (2017) A Masked, Randomized, Phase 3 Comparison of Triple Fixed-Combination Bimatoprost/Brimonidine/Timolol versus Fixed-Combination Brimonidine/Timolol for Lowering Intraocular Pressure. Journal of Ophthalmology 2017, pages 1-9.
Crossref
Tetsuya Yamamoto, Toru Ikegami, Yuji Ishikawa & Satoru Kikuchi. (2016) Randomized, Controlled, Phase 3 Trials of Carteolol/Latanoprost Fixed Combination in Primary Open-Angle Glaucoma or Ocular Hypertension. American Journal of Ophthalmology 171, pages 35-46.
Crossref
Kai Kaarniranta, Kirsi Ikäheimo, Eliisa Mannermaa & Auli Ropo. (2015) Pharmacokinetics, Efficacy, and Safety of the Preservative-free Fixed Combination of Tafluprost 0.0015 % and Timolol 0.5 % in Healthy Volunteers: A Phase I Comparison vs. the Corresponding Preservative-free Monotherapies. Clinical Pharmacokinetics 55:4, pages 485-494.
Crossref
Paul Harasymowycz, Catherine Birt, Patrick Gooi, Lisa Heckler, Cindy Hutnik, Delan Jinapriya, Lesya Shuba, David Yan & Radmila Day. (2016) Medical Management of Glaucoma in the 21st Century from a Canadian Perspective. Journal of Ophthalmology 2016, pages 1-22.
Crossref
Najam A. Sharif. (2015) Novel Potential Treatment Modalities for Ocular Hypertension: Focus on Angiotensin and Bradykinin System Axes. Journal of Ocular Pharmacology and Therapeutics 31:3, pages 131-145.
Crossref
Doreen SchmidlLeopold SchmettererGerhard GarhöferAlina Popa-Cherecheanu. (2015) Pharmacotherapy of Glaucoma. Journal of Ocular Pharmacology and Therapeutics 31:2, pages 63-77.
Crossref
Stefano A. Gandolfi, John Lim, Ana Cristina Sanseau, Juan Camilo Parra Restrepo & Thomas Hamacher. (2014) Randomized Trial of Brinzolamide/Brimonidine Versus Brinzolamide Plus Brimonidine for Open-Angle Glaucoma or Ocular Hypertension. Advances in Therapy 31:12, pages 1213-1227.
Crossref
Gábor Holló, Jouni Vuorinen, Juhani Tuominen, Teppo Huttunen, Auli Ropo & Norbert Pfeiffer. (2014) Fixed-Dose Combination of Tafluprost and Timolol in the Treatment of Open-Angle Glaucoma and Ocular Hypertension: Comparison with Other Fixed-Combination Products. Advances in Therapy 31:9, pages 932-944.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.