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Expert Opinion on Pharmacotherapy Volume 7, 2006 - Issue 6
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Key Paper Evaluation

Is amlodipine the best initial monotherapy for hypertension?

DAHLOF B, SEVER PS, POULTER NR et al.: Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicenter randomised controlled trial. Lancet (2005) 366:895-906 Citation and POULTER NR, WEDEL H, DAHLOP B et al.: Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA). Lancet (2005) 366:907-913 Citation.

Sheila A Doggrell Senior Lecturer, School of Science, Charles Darwin University, PO Box 41246, Casuarina, Northern Territory 0811, Australia . [email protected]
Pages 829-832 | Published online: 24 Mar 2006

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Roberto Ferrari. (2008) Optimizing the treatment of hypertension and stable coronary artery disease: clinical evidence for fixed-combination perindopril/amlodipine. Current Medical Research and Opinion 24:12, pages 3543-3557.
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Articles from other publishers (2)

Stefano Taddei. (2015) Combination Therapy in Hypertension: What Are the Best Options According to Clinical Pharmacology Principles and Controlled Clinical Trial Evidence?. American Journal of Cardiovascular Drugs 15:3, pages 185-194.
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Francisco Palacios, Esther Herrán, Gloria Rubiales & Concepción Alonso. (2007) Regioselective synthesis of pyridines and dihydropyridines derived from β-amino acids and aminophosphonates by reaction of N-vinylic phosphazenes with α,β-unsaturated ketones. Tetrahedron 63:25, pages 5669-5676.
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