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Key Paper Evaluation

Is amlodipine the best initial monotherapy for hypertension?

DAHLOF B, SEVER PS, POULTER NR et al.: Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicenter randomised controlled trial. Lancet (2005) 366:895-906 Citation and POULTER NR, WEDEL H, DAHLOP B et al.: Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA). Lancet (2005) 366:907-913 Citation.

Pages 829-832 | Published online: 24 Mar 2006

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