528
Views
48
CrossRef citations to date
0
Altmetric
Drug Evaluation

The echinocandin micafungin: a review of the pharmacology, spectrum of activity, clinical efficacy and safety

&
Pages 1155-1166 | Published online: 22 May 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Matteo Bassetti, Daniele Roberto Giacobbe, Antonio Vena & Susanna Esposito. (2022) An overview of micafungin as a treatment option for invasive candidiasis in pediatric patients younger than 4 months old. Expert Opinion on Pharmacotherapy 23:18, pages 1987-1993.
Read now
Nahed Abdel-Haq, Stephanie M. Smith & Basim I. Asmar. (2022) Micafungin injection for the treatment of invasive candidiasis in pediatric patients under 4 months of age. Expert Review of Anti-infective Therapy 20:4, pages 493-505.
Read now
Gabriel Davi Marena, Matheus Aparecido dos Santos Ramos, Taís Maria Bauab & Marlus Chorilli. (2021) Biological Properties and Analytical Methods for Micafungin: A Critical Review. Critical Reviews in Analytical Chemistry 51:4, pages 312-328.
Read now
Xin-Er Li, Jin-Jing Wang, Supatcha Phornsanthia, Xiangsheng Yin & Qi Li. (2014) Strengthening of Cell Wall Structure Enhances Stress Resistance and Fermentation Performance in Lager Yeast. Journal of the American Society of Brewing Chemists 72:2, pages 88-94.
Read now
Corrado Girmenia & Anna Paola Iori. (2012) Safety and interactions of new antifungals in stem cell transplant recipients. Expert Opinion on Drug Safety 11:5, pages 803-818.
Read now
F. Peláez, J. Collado, G. Platas, D.P. Overy, J. Martín, F. Vicente, A. González del Val, A. Basilio, M. De la Cruz, J.R. Tormo, A. Fillola, F. Arenal, M. Villareal, V. Rubio, H.O. Baral, R. Galán & G.F. Bills. (2011) Phylogeny and intercontinental distribution of the pneumocandin-producing anamorphic fungus Glarea lozoyensis . Mycology 2:1, pages 1-17.
Read now
Mario Cruciani & Giovanni Serpelloni. (2008) Management of Candida infections in the adult intensive care unit. Expert Opinion on Pharmacotherapy 9:2, pages 175-191.
Read now

Articles from other publishers (41)

Anastasiia A. Zakharova, Svetlana S. Efimova, Valeriy N. Yuskovets, Igor P. Yakovlev, Zara M. Sarkisyan & Olga S. Ostroumova. (2020) 1,3-Thiazine, 1,2,3,4-Dithiadiazole, and Thiohydrazide Derivatives Affect Lipid Bilayer Properties and Ion-Permeable Pores Induced by Antifungals. Frontiers in Cell and Developmental Biology 8.
Crossref
Martyna Mroczyńska & Anna Brillowska-Dąbrowska. (2020) Review on Current Status of Echinocandins Use. Antibiotics 9:5, pages 227.
Crossref
Annie Lee, Brendan Prideaux, Matthew Zimmerman, Claire Carter, Stephen Barat, David Angulo, Véronique Dartois, David S. Perlin & Yanan Zhao. (2020) Penetration of Ibrexafungerp (Formerly SCY-078) at the Site of Infection in an Intra-abdominal Candidiasis Mouse Model. Antimicrobial Agents and Chemotherapy 64:3.
Crossref
Alexander V. Veselov. (2020) The current place of echinocandins in the treatment and prophylaxis of invasive fungal infections. Clinical Microbiology and Antimicrobial Chemotherapy, pages 197-209.
Crossref
Yanan Zhao, Brendan Prideaux, Shane Baistrocchi, Donald C Sheppard & David S Perlin. (2019) Beyond tissue concentrations: antifungal penetration at the site of infection. Medical Mycology 57:Supplement_2, pages S161-S167.
Crossref
Yanan Zhao, Min Hee Lee, Padmaja Paderu, Annie Lee, Cristina Jimenez-Ortigosa, Steven Park, Robert S. Mansbach, Karen Joy Shaw & David S. Perlin. (2018) Significantly Improved Pharmacokinetics Enhances In Vivo Efficacy of APX001 against Echinocandin- and Multidrug-Resistant Candida Isolates in a Mouse Model of Invasive Candidiasis . Antimicrobial Agents and Chemotherapy 62:10.
Crossref
Yasmine Nivoix, Dominique Levêque, Raoul Herbrecht & Geneviève Ubeaud-Séquier. 2018. Pharmacie Clinique et Thérapeutique. Pharmacie Clinique et Thérapeutique 893 924.e1 .
Yanan Zhao, Brendan Prideaux, Yoji Nagasaki, Min Hee Lee, Pei-Yu Chen, Landry Blanc, Hsinpin Ho, Cornelius J. Clancy, Minh Hong Nguyen, Véronique Dartois & David S. Perlin. (2017) Unraveling Drug Penetration of Echinocandin Antifungals at the Site of Infection in an Intra-abdominal Abscess Model. Antimicrobial Agents and Chemotherapy 61:10.
Crossref
David S. Perlin. 2017. Candida albicans: Cellular and Molecular Biology. Candida albicans: Cellular and Molecular Biology 471 489 .
Nasrullah Undre, Benjamin Pretorius & Paul Stevenson. (2014) Pharmacokinetics of micafungin in subjects with severe hepatic dysfunction. European Journal of Drug Metabolism and Pharmacokinetics 40:3, pages 285-293.
Crossref
John H. Rex & David A. Stevens. 2015. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases 479 494.e4 .
Claudia Langebrake, Holger Rohde, Heinrich Lellek, Christine Wolschke & Nicolaus M. Kröger. (2014) Micafungin as antifungal prophylaxis in recipients of allogeneic hematopoietic stem cell transplantation: results of different dosage levels in clinical practice. Clinical Transplantation 28:3, pages 286-291.
Crossref
David A. Stevens. (2012) Advances in systemic antifungal therapy. Clinics in Dermatology 30:6, pages 657-661.
Crossref
Vibha C.A. Desai, Teresa M. Cavanaugh, Christina M.L. Kelton, Jeff J. Guo & Pamela C. Heaton. (2012) Trends in the Utilization of, Spending on, and Prices for Outpatient Antifungal Agents in US Medicaid Programs: 1991–2009. Clinical Therapeutics 34:10, pages 2118-2131.e1.
Crossref
Junxiang Guo, Honggang Hu, Qingjie Zhao, Ting Wang, Yan Zou, Shichong Yu, Qiuye Wu & Zhongwu Guo. (2012) Synthesis and Antifungal Activities of Glycosylated Derivatives of the Cyclic Peptide Fungicide Caspofungin. ChemMedChem 7:8, pages 1496-1503.
Crossref
Maiken Cavling Arendrup, David S. Perlin, Rasmus Hare Jensen, Susan Julie Howard, Joanne Goodwin & William Hope. (2012) Differential In Vivo Activities of Anidulafungin, Caspofungin, and Micafungin against Candida glabrata Isolates with and without FKS Resistance Mutations . Antimicrobial Agents and Chemotherapy 56:5, pages 2435-2442.
Crossref
Malcolm D. Richardson & David W. Warnock. 2012. Fungal Infection. Fungal Infection 32 90 .
M.A. Pfaller, D.J. Diekema, D. Andes, M.C. Arendrup, S.D. Brown, S.R. Lockhart, M. Motyl & D.S. Perlin. (2011) Clinical breakpoints for the echinocandins and Candida revisited: Integration of molecular, clinical, and microbiological data to arrive at species-specific interpretive criteria. Drug Resistance Updates 14:3, pages 164-176.
Crossref
Souzan B. Yanni, P. Brian Smith, Daniel K. BenjaminJrJr, Patrick F. Augustijns, Dhiren R. Thakker & Pieter P. Annaert. (2011) Higher clearance of micafungin in neonates compared with adults: role of age-dependent micafungin serum binding. Biopharmaceutics & Drug Disposition 32:4, pages 222-232.
Crossref
David S Perlin. (2011) Current perspectives on echinocandin class drugs. Future Microbiology 6:4, pages 441-457.
Crossref
Santiago Grau Cerrato, Sonia Luque Pardos & Olivia Ferrández Quirante. (2011) Características farmacocinéticas diferenciales de micafungina. Experiencia en poblaciones especiales. Enfermedades Infecciosas y Microbiología Clínica 29, pages 10-14.
Crossref
Sharon C.-A. Chen, Monica A. Slavin & Tania C. Sorrell. (2011) Echinocandin Antifungal Drugs in Fungal Infections. Drugs 71:1, pages 11-41.
Crossref
Russell E. Lewis & David S. Perlin. 2011. Principles and Practice of Cancer Infectious Diseases. Principles and Practice of Cancer Infectious Diseases 317 329 .
Andreas H. Groll, Dominik Schrey & Thomas J. Walsh. 2011. Essentials of Clinical Mycology. Essentials of Clinical Mycology 95 112 .
Daniel Mania, Kai Hilpert, Serge Ruden, Reinhard Fischer & Norio Takeshita. (2010) Screening for Antifungal Peptides and Their Modes of Action in Aspergillus nidulans . Applied and Environmental Microbiology 76:21, pages 7102-7108.
Crossref
Souzan B. Yanni, Patrick F. Augustijns, Daniel K. BenjaminJr.Jr., Kim L. R. Brouwer, Dhiren R. Thakker & Pieter P. Annaert. (2010) In Vitro Investigation of the Hepatobiliary Disposition Mechanisms of the Antifungal Agent Micafungin in Humans and Rats. Drug Metabolism and Disposition 38:10, pages 1848-1856.
Crossref
Jeniel E. Nett, Karen Marchillo, Carol A. Spiegel & David R. Andes. (2010) Development and Validation of an In Vivo Candida albicans Biofilm Denture Model . Infection and Immunity 78:9, pages 3650-3659.
Crossref
David W. Warnock. 2010. Antibiotic and Chemotherapy. Antibiotic and Chemotherapy 366 382 .
JOHN H. REX & DAVID A. STEVENS. 2010. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases 549 563 .
Allana J Sucher, Elias B Chahine & Holly E Balcer. (2009) Echinocandins: The Newest Class of Antifungals. Annals of Pharmacotherapy 43:10, pages 1647-1657.
Crossref
Bijoy P. Mathew & Mahendra Nath. (2009) Recent Approaches to Antifungal Therapy for Invasive Mycoses. ChemMedChem 4:3, pages 310-323.
Crossref
Miguel Salavert-Lletí & Rafael Zaragoza-Crespo. (2009) Papel futuro de la micafungina en el tratamiento de las micosis invasoras por hongos filamentosos. Revista Iberoamericana de Micología 26:1, pages 81-89.
Crossref
Mercedes Catalán-González & Juan Carlos Montejo-González. (2009) Farmacodinamia y farmacocinética de la micafungina en adultos, niños y neonatos. Revista Iberoamericana de Micología 26:1, pages 23-34.
Crossref
Guillermo Garcia-Effron, Steven Park & David S. Perlin. (2009) Correlating Echinocandin MIC and Kinetic Inhibition of fks1 Mutant Glucan Synthases for Candida albicans : Implications for Interpretive Breakpoints . Antimicrobial Agents and Chemotherapy 53:1, pages 112-122.
Crossref
David S. Perlin & William W. Hope. 2010. Aspergillosis: From Diagnosis to Prevention. Aspergillosis: From Diagnosis to Prevention 263 279 .
Gregory C. Adam, Craig A. Parish, Douglas Wisniewski, Juncai Meng, Min Liu, Kathleen Calati, Benjamin D. Stein, John Athanasopoulos, Paul Liberator, Terry Roemer, Guy Harris & Kevin T. Chapman. (2008) Application of Affinity Selection/Mass Spectrometry to Determine the Structural Isomer of Parnafungins Responsible for Binding Polyadenosine Polymerase. Journal of the American Chemical Society 130:49, pages 16704-16710.
Crossref
Russell E. Lewis. 2008. Aspergillus fumigatus and Aspergillosis . Aspergillus fumigatus and Aspergillosis 445 456 .
Craig A. Parish, Scott K. Smith, Kathleen Calati, Deborah Zink, Kenneth Wilson, Terry Roemer, Bo Jiang, Deming Xu, Gerald Bills, Gonzalo Platas, Fernando Peláez, Maria Teresa Díez, Nancy Tsou, Arlene E. McKeown, Richard G. Ball, Mary Ann Powles, Lai Yeung, Paul Liberator & Guy Harris. (2008) Isolation and Structure Elucidation of Parnafungins, Antifungal Natural Products that Inhibit mRNA Polyadenylation. Journal of the American Chemical Society 130:22, pages 7060-7066.
Crossref
N. Singh, M.M. Wagener, T.V. Cacciarelli & J. Levitsky. (2008) Antifungal Management Practices in Liver Transplant Recipients. American Journal of Transplantation 8:2, pages 426-431.
Crossref
Vera Meyer. (2008) A small protein that fights fungi: AFP as a new promising antifungal agent of biotechnological value. Applied Microbiology and Biotechnology 78:1, pages 17-28.
Crossref
. (2008) Current awareness: Pharmacoepidemiology and drug safety. Pharmacoepidemiology and Drug Safety 17:2.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.