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Drug Evaluations

Oral valproic acid for epilepsy - long-term experience in therapy and side effects

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Pages 285-292 | Published online: 17 Jan 2008

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Onur Ertik, Umar Faruk Magaji, Ozlem Sacan & Refiye Yanardag. (2023) Effect of Moringa oleifera leaf extract on valproate-induced oxidative damage in muscle. Drug and Chemical Toxicology 46:6, pages 1212-1222.
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Alessandra Morano, Luigi Iannone, Caterina Palleria, Martina Fanella, Anna Teresa Giallonardo, Giovambattista De Sarro, Emilio Russo & Carlo Di Bonaventura. (2019) Pharmacology of new and developing intravenous therapies for the management of seizures and epilepsy. Expert Opinion on Pharmacotherapy 20:1, pages 25-39.
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Kevin Cronin, Hernando Escobar, Karoly Szekeres, Eduardo Reyes-Vargas, Alan L. Rockwood, Mark C. Lloyd, Julio C. Delgado & George Blanck. (2013) Regulation of HLA-DR peptide occupancy by histone deacetylase inhibitors. Human Vaccines & Immunotherapeutics 9:4, pages 784-789.
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Natalia Lampon & J. Carlos Tutor. (2012) Apparent clearance of valproic acid in elderly epileptic patients: estimation of the confounding effect of albumin concentration. Upsala Journal of Medical Sciences 117:1, pages 41-46.
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Fructuoso Ayala-Guerrero, Daniel Castro-Domínguez, Erik L. Mateos-Salgado, Graciela Mexicano-Medina & Carlos Alberto Gutiérrez-Chávez. (2023) Effect of valproate on sleep patterns disturbed by epilepsy. Physiology & Behavior 259, pages 114054.
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Yutaka Ikeda, Yuya Tajika & Yukio Nagasaki. (2022) Design of self-assembling anti-epileptic drug for long-acting drug delivery in vivo . Biomaterials Science 10:21, pages 6307-6314.
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R. Jover, P. Soluyanova, E. Moro-Castaño, M. Moreno-Torres, A.V. Marco-Hernández, M. Tomas-Vila & J.V. Castell. (2022) SOC-V-11 New serum miRNA biomarkers to predict liver steatosis by valproic acid in paediatric epileptic patients. Toxicology Letters 368, pages S68.
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Sing Teang Kong, Hai-Shu Lin, Jianhong Ching, Huiqing Xie & Paul C. Ho. (2022) Dried Blood Spots as Matrix for Evaluation of Valproate Levels and the Immediate and Delayed Metabolomic Changes Induced by Single Valproate Dose Treatment. International Journal of Molecular Sciences 23:13, pages 7083.
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Kang-Hoon Kim, Ji Hoon Jung, Won-Seok Chung, Chang-Hun Lee & Hyeung-Jin Jang. (2021) Ferulic Acid Induces Keratin 6α via Inhibition of Nuclear β-Catenin Accumulation and Activation of Nrf2 in Wound-Induced Inflammation. Biomedicines 9:5, pages 459.
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Kenneth A. Myers, Uzziel Tamon, Ramanakumar V. Agnihotram & Saoussen Berrahmoune. (2020) Serum Levels of Valproic Acid and Carbamazepine Do Not Correlate Well with End-Organ Dysfunction. Epilepsy Research 163, pages 106343.
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Jessica Elena Mendieta-Wejebe, Arianna Silva-Trujillo, Martiniano Bello, Humberto L Mendoza-Figueroa, Norma Lizeth Galindo-Alvarez, Arnulfo Albores, Feliciano Tamay-Cach, Martha Cecilia Rosales-Hernández, Aurelio Romero-Castro & José Correa-Basurto. (2020) Exploring the biotransformation of N -(2-hydroxyphenyl)-2-propylpentanamide (an aryl valproic acid derivative) by CYP2C11, using in silico predictions and in vitro studies . Journal of Pharmacy and Pharmacology 72:7, pages 938-955.
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Wei Liu, Xiang Shang, Shuyong Yao & Feng Wang. (2019) A novel and nonderivatization method for the determination of valproic acid in human serum by two‐dimensional liquid chromatography. Biomedical Chromatography 34:1.
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Brenno Mazzariol, Antonella Pastorini, Alessandro di Luca & Natale Mario di Luca. (2019) Recent Medico-Legal Developments on the Issue of Epilepsy and Driver’s License Requirements in the Italian and European Legislation. Behavioural Neurology 2019, pages 1-5.
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Shabir Ahmad GanaiShabir Ahmad Ganai. 2019. Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders. Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders 39 58 .
Claire ZimmermanEric Yarnell. (2018) Herbal Medicines for Seizures. Alternative and Complementary Therapies 24:6, pages 281-290.
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Reza Shervin Badv, Arash Abbasi, Mahmoud Reza Ashrafi, Fakhreddin Shariatmadari & Omid Bayat. (2018) The Effect of Sodium Valproate on Urinary Frequency and Enuresis Compared to Carbamazepine in Children with Epilepsy. Iranian Journal of Pediatrics In Press:In Press.
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Byoung-San Moon, Wange Lu & Hong Ju Park. (2018) Valproic acid promotes the neuronal differentiation of spiral ganglion neural stem cells with robust axonal growth. Biochemical and Biophysical Research Communications 503:4, pages 2728-2735.
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