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Review

Developments in the pharmacotherapeutic management of spontaneous preterm labor

, BSc & , BSc MB ChB MD FRCOG
Pages 1153-1168 | Published online: 21 Apr 2008

Keep up to date with the latest research on this topic with citation updates for this article.

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Maryam Kashanian, Nooshin Eshraghi, Maryam Rahimi & Narges Sheikhansari. (2022) Evaluation of placental alpha microglobulin-1(PAMG1) accuracy for prediction of preterm delivery in women with the symptoms of spontaneous preterm labor; a comparison with cervical length and number of contractions. The Journal of Maternal-Fetal & Neonatal Medicine 35:3, pages 534-540.
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Callum D. Lamont, Jan Stener Jørgensen & Ronald F. Lamont. (2016) The safety of tocolytics used for the inhibition of preterm labour. Expert Opinion on Drug Safety 15:9, pages 1163-1173.
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Jan Stener Jørgensen, Louise Katrine Kjær Weile & Ronald Francis Lamont. (2014) Preterm labor: current tocolytic options for the treatment of preterm labor. Expert Opinion on Pharmacotherapy 15:5, pages 585-588.
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Shigehiko Mizutani, Taihei Tsunemi, Eita Mizutani, Akira Hattori, Masafumi Tsujimoto & Hiroshi Kobayashi. (2013) New insights into the role of aminopeptidases in the treatment for both preeclampsia and preterm labor. Expert Opinion on Investigational Drugs 22:11, pages 1425-1436.
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S. S. Saleh, M. Q. Al-Ramahi & F. A. Al Kazaleh. (2013) Atosiban and nifedipine in the suppression of pre-term labour: A comparative study. Journal of Obstetrics and Gynaecology 33:1, pages 43-45.
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Mark P. Hehir, Hugh D. O’Connor, Etaoin M. Kent, Michael S. Robson, Declan P. Keane, Michael P. Geary & Fergal D. Malone. (2012) Early and late preterm delivery rates – a comparison of differing tocolytic policies in a single urban population. The Journal of Maternal-Fetal & Neonatal Medicine 25:11, pages 2234-2236.
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Olaleye Sanu & Ronald F Lamont. (2010) Critical appraisal and clinical utility of atosiban in the management of preterm labor. Therapeutics and Clinical Risk Management 6, pages 191-199.
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GS Jayasooriya & RF Lamont. (2009) The use of progesterone and other progestational agents to prevent spontaneous preterm labour and preterm birth. Expert Opinion on Pharmacotherapy 10:6, pages 1007-1016.
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Felice Petraglia & Gerard H. A. Visser. (2009) Prevention and management of preterm labour. The Journal of Maternal-Fetal & Neonatal Medicine 22:sup2, pages 24-30.
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Gerald Gimpl. (2008) Oxytocin receptor ligands: a survey of the patent literature. Expert Opinion on Therapeutic Patents 18:11, pages 1239-1251.
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Articles from other publishers (17)

Ronald F. Lamont & Jan S. Jørgensen. (2019) Safety and Efficacy of Tocolytics for the Treatment of Spontaneous Preterm Labour. Current Pharmaceutical Design 25:5, pages 577-592.
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Sung Hye Kim, Lucia Riaposova, Hauwa Ahmed, Oliver Pohl, André Chollet, Jean-Pierre Gotteland, Aylin Hanyaloglu, Phillip R. Bennett & Vasso Terzidou. (2019) Oxytocin Receptor Antagonists, Atosiban and Nolasiban, Inhibit Prostaglandin F2α-induced Contractions and Inflammatory Responses in Human Myometrium. Scientific Reports 9:1.
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Oliver Pohl, André Chollet, Sung Hye Kim, Lucia Riaposova, François Spézia, Frédéric Gervais, Philippe Guillaume, Philippe Lluel, Murielle Méen, Frédérique Lemaux, Vasso Terzidou, Phillip R. Bennett & Jean-Pierre Gotteland. (2018) OBE022, an Oral and Selective Prostaglandin F 2 α Receptor Antagonist as an Effective and Safe Modality for the Treatment of Preterm Labor . Journal of Pharmacology and Experimental Therapeutics 366:2, pages 349-364.
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Min Kyoung KimSeung Mi LeeJung Won OhSo Yeon KimHye Gyeong JeongSun Min KimChan Wook ParkJong Kwan JunSeo-kyung HahnJoong Shin Park. (2018) Efficacy and side effect of ritodrine and magnesium sulfate in threatened preterm labor. Obstetrics & Gynecology Science 61:1, pages 63.
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Cynthia Gyamfi-Bannerman, Ramkumar Menon, Elizabeth A. Bonney, Siobhan M. Dolan, Mark Johnson, Ronald F. Lamont, Sam Mesiano, Amy P. Murtha, Leslie Myatt, Indira Mysorekar, Scott M Williams, Nanbert Zhong & Hanns Helmer. (2017) Novel thoughts on preterm birth research proceedings of the 13th annual preterm birth international collaborative (PREBIC) meeting. Seminars in Perinatology 41:7, pages 438-441.
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E. Friedlander, O. Feldstein, D. Mankuta, M. Yaari, A. Harel-Gadassi, R.P. Ebstein & N. Yirmiya. (2017) Response to Letter to Editor on “Social impairments among children perinatally exposed to oxytocin or oxytocin receptor antagonist”. Early Human Development 112, pages 62-63.
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Ronald F. Lamont & Jan Stener Jørgensen. (2017) Oxytocin-receptor antagonists in the aetiology of autism spectrum disorder. Early Human Development 112, pages 60-61.
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M Kashanian, Z Zamen & N Sheikhansari. (2014) Comparison between nitroglycerin dermal patch and nifedipine for treatment of preterm labor: a randomized clinical trial. Journal of Perinatology 34:9, pages 683-687.
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Manuela Pfinder, Anton E Kunst, Reinhold Feldmann, Manon van Eijsden & Tanja G M Vrijkotte. (2013) Preterm birth and small for gestational age in relation to alcohol consumption during pregnancy: stronger associations among vulnerable women? results from two large Western-European studies. BMC Pregnancy and Childbirth 13:1.
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Roger C. YoungGabriela Goloman. (2013) Allo- and Xeno-Reassembly of Human and Rat Myometrium from Cells and Scaffolds. Tissue Engineering Part A 19:19-20, pages 2112-2119.
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Nabila H. Saleem, Valerie A. Ferro, Ann M. Simpson, John Igoli, Alexander I. Gray & Robert M. Drummond. (2013) The Inhibitory Effect of Haloxylon salicornicum on Contraction of the Mouse Uterus . Evidence-Based Complementary and Alternative Medicine 2013, pages 1-10.
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Maryam Kashanian, Shohreh Bahasadri, Afsaneh Ghasemi & Saeedesadat Bathaee. (2013) Value of serum urocortin concentration in the prediction of preterm birth. Journal of Obstetrics and Gynaecology Research 39:1, pages 26-30.
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Maryam Kashanian, Shohreh Bahasadri & Bita Zolali. (2011) Comparison of the efficacy and adverse effects of nifedipine and indomethacin for the treatment of preterm labor. International Journal of Gynecology & Obstetrics 113:3, pages 192-195.
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Yanfang Guo, Christopher J. Longo, Rihua Xie, Shi Wu Wen, Mark C. Walker & Graeme N. Smith. (2011) Cost-Effectiveness of Transdermal Nitroglycerin Use for Preterm Labor. Value in Health 14:2, pages 240-246.
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Rekha Wuntakal & Tony Hollingworth. (2010) Leptin – A tocolytic agent for the future?. Medical Hypotheses 74:1, pages 81-82.
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Chia-Hui Lin, Shin-Yu Lin, Ming-Kwang Shyu, Shee-Uan Chen & Chien-Nan Lee. (2009) Randomized Trial of Oxytocin Antagonist Atosiban Versus Beta-adrenergic Agonists in the Treatment of Spontaneous Preterm Labor in Taiwanese Women. Journal of the Formosan Medical Association 108:6, pages 493-501.
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Anna Klukovits, Árpád Márki, Eszter Páldy, Sándor Benyhe, Márta Gálik, George Falkay & Róbert Gáspár. (2008) Inflammatory processes enhance cAMP-mediated uterus relaxation in the pregnant rat: the role of TNF-α. Naunyn-Schmiedeberg's Archives of Pharmacology 379:5, pages 501-510.
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