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Drug Evaluations

Peg-asparaginase for acute lymphoblastic leukemia

, MD
Pages 833-839 | Published online: 29 Mar 2010

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Chintan Vyas, Sandeep Jain, Gauri Kapoor, Anurag Mehta & Parul Takkar Chugh. (2018) Experience with generic pegylated L-asparaginase in children with acute lymphoblastic leukemia and monitoring of serum asparaginase activity. Pediatric Hematology and Oncology 35:5-6, pages 331-340.
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Abraham Chang, Michelle Kim, Maggie Seyer & Samit Patel. (2016) Allergic reactions associated with pegaspargase in adults. Leukemia & Lymphoma 57:7, pages 1665-1668.
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William C. Petersen$suffix/text()$suffix/text(), Dana Clark, Stacy L. Senn, W. Thomas Cash, Scott E. Gillespie, Courtney E. McCracken, Frank G. Keller & Glen Lew. (2014) Comparison of Allergic Reactions to Intravenous and Intramuscular Pegaspargase in Children with Acute Lymphoblastic Leukemia. Pediatric Hematology and Oncology 31:4, pages 311-317.
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Vaidehi Agrawal, Sarah EJ Alpini, Everett M Stone, Eugene P Frenkel & Arthur E Frankel. (2012) Targeting methionine auxotrophy in cancer: discovery & exploration. Expert Opinion on Biological Therapy 12:1, pages 53-61.
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Marina V. Pokrovskaya, Vadim S. Pokrovsky, Svetlana S. Aleksandrova, Nikolay N. Sokolov & Dmitry D. Zhdanov. (2022) Molecular Analysis of L-Asparaginases for Clarification of the Mechanism of Action and Optimization of Pharmacological Functions. Pharmaceutics 14:3, pages 599.
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Ran Li, Zehua Zhang, Xiaomei Pei & Xiaole Xia. (2020) Covalent Immobilization of L-Asparaginase and Optimization of Its Enzyme Reactor for Reducing Acrylamide Formation in a Heated Food Model System. Frontiers in Bioengineering and Biotechnology 8.
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Aaron Shmookler & Stephen Smith. (2017) Pegaspargase‐induced hypertriglyceridemia. Journal of Clinical Apheresis 33:1, pages 97-98.
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Jiabao Liang, Pengcheng Shi, Xutao Guo, Jie Li, Lingli He, Yan Wang, Qi Wei, Fen Huang, Zhiping Fan & Bing Xu. (2017) A retrospective comparison of Escherichia�coli and polyethylene glycol‑conjugated asparaginase for the treatment of adolescents and adults with newly diagnosed acute lymphoblastic leukemia. Oncology Letters.
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Ahmet Ulu & Burhan Ates. (2017) Immobilization of l -Asparaginase on Carrier Materials: A Comprehensive Review . Bioconjugate Chemistry 28:6, pages 1598-1610.
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Haroon Hasan, Omar Mohammad Shaikh, Shahrad Rod Rassekh, A. Fuchsia Howard & Karen Goddard. (2017) Comparison of hypersensitivity rates to intravenous and intramuscular PEG-asparaginase in children with acute lymphoblastic leukemia: A meta-analysis and systematic review. Pediatric Blood & Cancer 64:1, pages 81-88.
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Rodolfo J. Galindo, Justin Yoon, Craig Devoe & Alyson K. Myers. (2016) PEG-asparaginase induced severe hypertriglyceridemia. Archives of Endocrinology and Metabolism 60:2, pages 173-177.
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Vicki Nussbaum, Nicole Lubcke & Russell Findlay. (2014) Hyperammonemia secondary to asparaginase: A case series. Journal of Oncology Pharmacy Practice 22:1, pages 161-164.
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Lesleigh S. Abbott, Maria Zakova, Furqan Shaikh, Nisha Shewaramani, Angela Punnett & L. Lee Dupuis. (2015) Allergic Reactions Associated with Intravenous Versus Intramuscular Pegaspargase: A Retrospective Chart Review. Pediatric Drugs 17:4, pages 315-321.
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