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Expert Opinion on Biological Therapy Volume 11, 2011 - Issue 1
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siRNA therapy for cancer and non-lethal diseases such as arthritis and osteoporosis

Qin Shi University of Montreal, Sacré-Coeur Hospital, Research Center, Orthopaedics Research Laboratory, 5400 West Gouin Blvd., Montreal, Quebec H4J 1C5, Canada +514 338 2222 ext. 3043; +514 338 2694; [email protected]
,
Xiao-Ling Zhang Shanghai Jiao Tong University, Institute of Health Sciences, School of Medicine and Shanghai Institutes for the Biological Sciences, Chinese Academy of Sciences, 225 South Chongqing Road, Shanghai 200025, China; Shanghai Jiao Tong University, Ninth People's Hospital, School of Medicine, Department of Orthopaedics, 639 Zhizaoju Road, Shanghai 200011, China
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Ke-Rong Dai Shanghai Jiao Tong University, Institute of Health Sciences, School of Medicine and Shanghai Institutes for the Biological Sciences, Chinese Academy of Sciences, 225 South Chongqing Road, Shanghai 200025, China; Shanghai Jiao Tong University, Ninth People's Hospital, School of Medicine, Department of Orthopaedics, 639 Zhizaoju Road, Shanghai 200011, China
,
Mohamed Benderdour University of Montreal, Sacré-Coeur Hospital, Research Center, Orthopaedics Research Laboratory, 5400 West Gouin Blvd., Montreal, Quebec H4J 1C5, Canada +514 338 2222 ext. 3043; +514 338 2694; [email protected]
&
Julio C Fernandes University of Montreal, Sacré-Coeur Hospital, Research Center, Orthopaedics Research Laboratory, 5400 West Gouin Blvd., Montreal, Quebec H4J 1C5, Canada +514 338 2222 ext. 3043; +514 338 2694; [email protected]
Pages 5-16 | Published online: 09 Nov 2010

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Zoya Iqbal, Jiang Xia, Ghulam Murtaza, Maryam Shabbir, Khurrum Rehman, Liang Yujie & Li Duan. (2023) Targeting WNT signalling pathways as new therapeutic strategies for osteoarthritis. Journal of Drug Targeting 31:10, pages 1027-1049.
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Wei Shao, Arghya Paul, Sana Abbasi, Parminder S Chahal, Jimmy A Mena, Johnny Montes, Amine Kamen & Satya Prakash. (2012) A novel polyethyleneimine-coated adeno-associated virus-like particle formulation for efficient siRNA delivery in breast cancer therapy: preparation and in vitro analysis. International Journal of Nanomedicine 7, pages 1575-1586.
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Oleh Taratula, Olga B. Garbuzenko, Alex M. Chen & Tamara Minko. (2011) Innovative strategy for treatment of lung cancer: targeted nanotechnology-based inhalation co-delivery of anticancer drugs and siRNA. Journal of Drug Targeting 19:10, pages 900-914.
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Articles from other publishers (11)

Jinyu Li, Guiyu Feng, Haoyang He, Haolin Wang, Jia Tang, Aiqing Han, Xiaohong Mu & Weifeng Zhu. (2022) Development of software enabling Chinese medicine-based precision treatment for osteoporosis at the gene and pathway levels. Chinese Medicine 17:1.
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Ran Ding, Jinsong Zhou, Jianguo Xu, Huajie Lu, Tingting Zhang, Xiong Xiang & Zhen Shi. (2021) Circ_0045714/miR-331-3p interaction affects IL-1β-evoked human articular chondrocyte injury through regulating PIK3R3 in a ceRNA regulatory cascade. Journal of Orthopaedic Surgery and Research 16:1.
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Jinxia Zhang, Ling Jiang, Lihong Sun, Ping Wang, Suhui Sun, Menghong Xu, Lulu Zhang, Shumin Wang, Xiaolong Liang & Ligang Cui. (2021) Targeted drug delivery strategies for the treatment of rheumatoid arthritis. Science China Life Sciences 64:7, pages 1187-1189.
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Ying Yang & Sijie Fang. (2017) Small non-coding RNAs-based bone regulation and targeting therapeutic strategies. Molecular and Cellular Endocrinology 456, pages 16-35.
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Shiping Shi, Zhentao Man, Wei Li, Shui Sun & Wei Zhang. (2016) Silencing of Wnt5a prevents interleukin-1β-induced collagen type II degradation in rat chondrocytes. Experimental and Therapeutic Medicine 12:5, pages 3161-3166.
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Kyla F. Ortved & Alan J. Nixon. (2016) Cell-based cartilage repair strategies in the horse. The Veterinary Journal 208, pages 1-12.
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Tae-Hyun Kim, Rajendra K. Singh, Min Sil Kang, Joong-Huyn Kim & Hae-Won Kim. (2016) Inhibition of osteoclastogenesis through siRNA delivery with tunable mesoporous bioactive nanocarriers. Acta Biomaterialia 29, pages 352-364.
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Chen-hui Shi, Wei-shan Wang, Zhen-dong Zhang, Chang-jun Li, Feng-jing Guo, Feng Li & An-ming Chen. (2015) Effect of lentivirus-mediated uPA silencing on the proliferation and apoptosis of chondrocytes and the expression of MMPs. Journal of Huazhong University of Science and Technology [Medical Sciences] 35:1, pages 111-116.
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Yuwei Wang & David W Grainger. (2013) Developing siRNA therapies to address osteoporosis. Therapeutic Delivery 4:10, pages 1239-1246.
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Xinglu Jiang, Guobao Wang, Ru Liu, Yaling Wang, Yongkui Wang, Xiaozhong Qiu & Xueyun Gao. (2013) RNase non-sensitive and endocytosis independent siRNA delivery system: delivery of siRNA into tumor cells and high efficiency induction of apoptosis. Nanoscale 5:16, pages 7256.
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Michael E. Angeline & Scott A. Rodeo. (2012) Biologics in the Management of Rotator Cuff Surgery. Clinics in Sports Medicine 31:4, pages 645-663.
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