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Induced regulatory T cells in inhibitory microenvironments created by cancer

, PhD MDHC

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Qian Ye, Xiaowen Han & Zhengsheng Wu. (2020) Bioinformatics analysis to screen key prognostic genes in the breast cancer tumor microenvironment. Bioengineered 11:1, pages 1280-1300.
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Theresa L Whiteside. (2015) The role of regulatory T cells in cancer immunology. ImmunoTargets and Therapy 4, pages 159-171.
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Theresa L Whiteside. (2015) The potential of tumor-derived exosomes for noninvasive cancer monitoring. Expert Review of Molecular Diagnostics 15:10, pages 1293-1310.
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Alison Sehgal, Theresa L Whiteside & Michael Boyiadzis. (2015) Programmed death-1 checkpoint blockade in acute myeloid leukemia. Expert Opinion on Biological Therapy 15:8, pages 1191-1203.
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Sotirios P. Fortis, Michael Sofopoulos, Maria Goulielmaki, Niki Arnogiannaki, Alexandros Ardavanis, Sonia A. Perez, Angelos D. Gritzapis & Constantin N. Baxevanis. (2022) Association between Intratumoral CD8+ T Cells with FoxP3+ and CD163+ Cells: A Potential Immune Intrinsic Negative Feedback Mechanism for Acquired Immune Resistance. Cancers 14:24, pages 6208.
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Yi He, Haiting Zhou, Xiaojian Huang, Yunkun Qu, Yingguang Wang, Wenbin Pei, Rui Zhang, Sheng Chen & Hongbo You. (2022) Infiltration of LPAR5+ macrophages in osteosarcoma tumor microenvironment predicts better outcomes. Frontiers in Immunology 13.
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Elham Gholipour, Houman Kahroba, Nasim Soltani, Parisa Samadi, Parisa Sarvarian, Sajjad Vakili‐Samiani, Abbas Ali Hosein Pour Feizi, Mohammad Sadegh Soltani‐Zangbar, Adel Baghersalimi, Bahram Darbandi, Aliakbar Movassaghpour, Mehdi Talebi, Roza Motavalli, Amir Mehdizadeh, Abdolhassan Kazemi & Mehdi Yousefi. (2022) Paediatric pre‐B acute lymphoblastic leukaemia‐derived exosomes regulate immune function in human T cells. Journal of Cellular and Molecular Medicine 26:16, pages 4566-4576.
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Ram Hari Pokhrel, Suman Acharya, Jae-Hee Ahn, Ye Gu, Mahesh Pandit, Jong-Oh Kim, Yun-Yong Park, Ben Kang, Hyun-Jeong Ko & Jae-Hoon Chang. (2021) AMPK promotes antitumor immunity by downregulating PD-1 in regulatory T cells via the HMGCR/p38 signaling pathway. Molecular Cancer 20:1.
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V. E. Mukhin, Yu. S. Konstantinova, R. R. Gimadiev & N. V. Mazurchik. (2021) Horizons of development of immunotherapy for malignant liver tumors. Experimental and Clinical Gastroenterology:7, pages 81-89.
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Alexa C. Glencer, Jasmine M. Wong, Nola M. Hylton, Gregor Krings, Emma McCune, Harriet T. Rothschild, Tristan A. Loveday, Michael D. Alvarado, Laura J. Esserman & Michael J. Campbell. (2021) Modulation of the immune microenvironment of high-risk ductal carcinoma in situ by intralesional pembrolizumab injection. npj Breast Cancer 7:1.
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Gary D Luker, Jinming Yang, Ann Richmond, Stefania Scala, Claudio Festuccia, Margret Schottelius, Hans-Jürgen Wester & Johann Zimmermann. (2021) At the Bench: Pre-clinical evidence for multiple functions of CXCR4 in cancer. Journal of Leukocyte Biology 109:5, pages 969-989.
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Weinan Wang, Rui Zou, Ye Qiu, Jishuang Liu, Yu Xin, Tianzhu He & Zhidong Qiu. (2021) Interaction Networks Converging on Immunosuppressive Roles of Granzyme B: Special Niches Within the Tumor Microenvironment. Frontiers in Immunology 12.
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Veronica Olivo Pimentel, Damiënne Marcus, Alexander MA van der Wiel, Natasja G Lieuwes, Rianne Biemans, Relinde IY Lieverse, Dario Neri, Jan Theys, Ala Yaromina, Ludwig J Dubois & Philippe Lambin. (2021) Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19–IL2 cures poorly immunogenic tumors when combined with radiotherapy. Journal for ImmunoTherapy of Cancer 9:3, pages e001764.
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Koushan Sineh Sepehr, Alireza Razavi, Zuhair Mohammad Hassan, Abdolreza Fazel, Meghdad Abdollahpour-Alitappeh, Majid Mossahebi-Mohammadi, Mir Saeed Yekaninejad, Behrouz Farhadihosseinabadi & Seyed Mahmoud Hashemi. (2020) Comparative immunomodulatory properties of mesenchymal stem cells derived from human breast tumor and normal breast adipose tissue. Cancer Immunology, Immunotherapy 69:9, pages 1841-1854.
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Jan C. Schroeder, Lisa Puntigam, Linda Hofmann, Sandra S. Jeske, Inga J. Beccard, Johannes Doescher, Simon Laban, Thomas K. Hoffmann, Cornelia Brunner, Marie-Nicole Theodoraki & Patrick J. Schuler. (2020) Circulating Exosomes Inhibit B Cell Proliferation and Activity. Cancers 12:8, pages 2110.
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James D. FisherStephen C. Balmert, Wensheng Zhang, Riccardo Schweizer, Jonas T. SchniderChiaki KomatsuLiwei DongVasil E. ErbasJignesh V. UnadkatAli Mübin AralAbhinav P. AcharyaYalcin KulahciHeth R. Turnquist, Angus W. ThomsonMario G. SolariVijay S. GorantlaSteven R. Little. (2019) Treg-inducing microparticles promote donor-specific tolerance in experimental vascularized composite allotransplantation. Proceedings of the National Academy of Sciences 116:51, pages 25784-25789.
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Guanglin Cui, Zhenfeng Li, Jingli Ren & Aping Yuan. (2019) IL-33 in the tumor microenvironment is associated with the accumulation of FoxP3-positive regulatory T cells in human esophageal carcinomas. Virchows Archiv 475:5, pages 579-586.
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Eva Leufven & Øystein Bruserud. (2019) Immunosuppression and Immunotargeted Therapy in Acute Myeloid Leukemia - The Potential Use of Checkpoint Inhibitors in Combination with Other Treatments. Current Medicinal Chemistry 26:28, pages 5244-5261.
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Constantin N. Baxevanis, Michael Sofopoulos, Sotirios P. Fortis & Sonia A. Perez. (2019) The role of immune infiltrates as prognostic biomarkers in patients with breast cancer. Cancer Immunology, Immunotherapy 68:10, pages 1671-1680.
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Florina Iliescu, Danilo Vrtačnik, Pavel Neuzil & Ciprian Iliescu. (2019) Microfluidic Technology for Clinical Applications of Exosomes. Micromachines 10:6, pages 392.
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Ilaria Porcellato, Chiara Brachelente, Livia De Paolis, Laura Menchetti, Serenella Silvestri, Monica Sforna, Gaia Vichi, Selina Iussich & Luca Mechelli. (2018) FoxP3 and IDO in Canine Melanocytic Tumors. Veterinary Pathology 56:2, pages 189-199.
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Xue Wang, Feng-Feng Ping, Sahar Bakht, Jingjing Ling & Waseem Hassan. (2019) Immunometabolism features of metabolic deregulation and cancer. Journal of Cellular and Molecular Medicine 23:2, pages 694-701.
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Yi-Na Liu, Han Zhang, Lin Zhang, Ting-Ting Cai, Dai-Jia Huang, Jia He, Huan-He Ni, Fang-Jian Zhou, Xiao-Shi Zhang & Jiang Li. (2019) Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer. Cell Death & Disease 10:2.
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David A. Bernal-Estévez, Oscar García, Ramiro Sánchez & Carlos A. Parra-López. (2018) Monitoring the responsiveness of T and antigen presenting cell compartments in breast cancer patients is useful to predict clinical tumor response to neoadjuvant chemotherapy. BMC Cancer 18:1.
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Chunping Ao & Kang Zeng. (2018) The role of regulatory T cells in pathogenesis and therapy of human papillomavirus-related diseases, especially in cancer. Infection, Genetics and Evolution 65, pages 406-413.
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Lien Lybaert, Karim Vermaelen, Bruno G. De Geest & Lutz Nuhn. (2018) Immunoengineering through cancer vaccines – A personalized and multi-step vaccine approach towards precise cancer immunity. Journal of Controlled Release 289, pages 125-145.
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Robert D. Leone, Im-Meng Sun, Min-Hee Oh, Im-Hong Sun, Jiayu Wen, Judson Englert & Jonathan D. Powell. (2018) Inhibition of the adenosine A2a receptor modulates expression of T cell coinhibitory receptors and improves effector function for enhanced checkpoint blockade and ACT in murine cancer models. Cancer Immunology, Immunotherapy 67:8, pages 1271-1284.
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Naoki Hosaka. (2018) Role of Regulatory T Cells in Tumor-Bearing Mice Treated with Allo-Hematopoietic Stem Cell Transplantation Plus Thymus Transplantation. Journal of Immunology Research 2018, pages 1-7.
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