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Drug Evaluations

Update on obinutuzumab in the treatment of B-cell malignancies

, BSc PhD MRCP FRCR FRCPath, , BSc PhD, & , BSc PhD

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Sonia Cerquozzi & Carolyn Owen. (2015) Clinical role of obinutuzumab in the treatment of naive patients with chronic lymphocytic leukemia. Biologics: Targets and Therapy 9, pages 13-22.
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Myrna R Nahas & Jon E Arnason. (2015) Targeting CD20 in chronic lymphocytic leukemia. Blood and Lymphatic Cancer: Targets and Therapy 5, pages 43-53.
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Jon E Arnason & Jennifer R Brown. (2015) Obinutuzumab: its use in the management of chronic lymphocytic leukemia. Expert Opinion on Orphan Drugs 3:7, pages 843-853.
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Catherine Rioufol & Gilles Salles. (2015) Biosimilar monoclonal antibodies in lymphoma: a critical appraisal. Expert Review of Anticancer Therapy 15:5, pages 569-578.
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Uwe Reusch, Johannes Duell, Kristina Ellwanger, Carmen Herbrecht, Stefan HJ Knackmuss, Ivica Fucek, Markus Eser, Fionnuala McAleese, Vera Molkenthin, Fabrice Le Gall, Max Topp, Melvyn Little & Eugene A Zhukovsky. (2015) A tetravalent bispecific TandAb (CD19/CD3), AFM11, efficiently recruits T cells for the potent lysis of CD19+ tumor cells. mAbs 7:3, pages 584-604.
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Articles from other publishers (13)

Fran Lukšić, Anika Mijakovac, Goran Josipović, Vedrana Vičić Bočkor, Jasminka Krištić, Ana Cindrić, Martina Vinicki, Filip Rokić, Oliver Vugrek, Gordan Lauc & Vlatka Zoldoš. (2023) Long-Term Culturing of FreeStyle 293-F Cells Affects Immunoglobulin G Glycome Composition. Biomolecules 13:8, pages 1245.
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Lai-Xi Wang. 2023. Encyclopedia of Cell Biology. Encyclopedia of Cell Biology 500 505 .
Dalma Deak, Cristina Pop, Alina-Andreea Zimta, Ancuta Jurj, Alexandra Ghiaur, Sergiu Pasca, Patric Teodorescu, Angela Dascalescu, Ion Antohe, Bogdan Ionescu, Catalin Constantinescu, Anca Onaciu, Raluca Munteanu, Ioana Berindan-Neagoe, Bobe Petrushev, Cristina Turcas, Sabina Iluta, Cristina Selicean, Mihnea Zdrenghea, Alina Tanase, Catalin Danaila, Anca Colita, Andrei Colita, Delia Dima, Daniel Coriu, Hermann Einsele & Ciprian Tomuleasa. (2019) Let’s Talk About BiTEs and Other Drugs in the Real-Life Setting for B-Cell Acute Lymphoblastic Leukemia. Frontiers in Immunology 10.
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Lai-Xi WangXin TongChao LiJohn P. GiddensTiezheng Li. (2019) Glycoengineering of Antibodies for Modulating Functions. Annual Review of Biochemistry 88:1, pages 433-459.
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Xin Tong, Tiezheng Li, Jared Orwenyo, Christian Toonstra & Lai-Xi Wang. (2018) One-pot enzymatic glycan remodeling of a therapeutic monoclonal antibody by endoglycosidase S (Endo-S) from Streptococcus pyogenes. Bioorganic & Medicinal Chemistry 26:7, pages 1347-1355.
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E J Cheadle, G Lipowska-Bhalla, S J Dovedi, E Fagnano, C Klein, J Honeychurch & T M Illidge. (2016) A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells. Leukemia 31:7, pages 1611-1621.
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Wei Wen Chien, Charlène Niogret, Romain Jugé, Loïc Lionnard, Aurélie Cornut-Thibaut, Jérôme Kucharczak, Ariel Savina, Gilles Salles & Abdel Aouacheria. (2017) Unexpected cross-reactivity of anti-cathepsin B antibodies leads to uncertainties regarding the mechanism of action of anti-CD20 monoclonal antibody GA101. Leukemia Research 55, pages 41-48.
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Tiezheng Li, Xin Tong, Qiang Yang, John P. Giddens & Lai-Xi Wang. (2016) Glycosynthase Mutants of Endoglycosidase S2 Show Potent Transglycosylation Activity and Remarkably Relaxed Substrate Specificity for Antibody Glycosylation Remodeling. Journal of Biological Chemistry 291:32, pages 16508-16518.
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Kristina Nalivaiko, Martin Hofmann, Karina Kober, Nadine Teichweyde, Peter H Krammer, Hans-Georg Rammensee, Ludger Grosse-Hovest & Gundram Jung. (2016) A Recombinant Bispecific CD20×CD95 Antibody With Superior Activity Against Normal and Malignant B-cells. Molecular Therapy 24:2, pages 298-305.
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Subhashini Archana Kadavakolan, Sonam Puri, Sandeep Sahay & Jitesh Joshi. (2016) An update on newer monoclonal antibodies in lymphoma therapy. Asian Journal of Oncology 02, pages 003-007.
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Narges Seyfizadeh, Nayer Seyfizadeh, Justin Hasenkamp & Sara Huerta-Yepez. (2016) A molecular perspective on rituximab: A monoclonal antibody for B cell non Hodgkin lymphoma and other affections. Critical Reviews in Oncology/Hematology 97, pages 275-290.
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Valentin Goede & Michael Hallek. (2015) Pharmacotherapeutic Management of Chronic Lymphocytic Leukaemia in Patients with Comorbidities: New Agents, New Hope. Drugs & Aging 32:11, pages 877-886.
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Valentin Goede, Christian Klein & Stephan Stilgenbauer. (2015) Obinutuzumab (GA101) for the Treatment of Chronic Lymphocytic Leukemia and Other B-Cell Non-Hodgkin's Lymphomas: A Glycoengineered Type II CD20 Antibody. Oncology Research and Treatment 38:4, pages 185-192.
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