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Yoshiyuki Hattori, Mari Nakamura, Nozomi Takeuchi, Kyoko Tamaki, Satono Shimizu, Yuki Yoshiike, Masamitsu Taguchi, Hiroaki Ohno, Kei-Ichi Ozaki & Hiraku Onishi. (2019) Effect of cationic lipid in cationic liposomes on siRNA delivery into the lung by intravenous injection of cationic lipoplex. Journal of Drug Targeting 27:2, pages 217-227.
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Ji Young Lee, Helena M. Linge, Kanta Ochani, Ke Lin & Edmund J. Miller. (2016) Regulation of angiopoietin-2 secretion from human pulmonary microvascular endothelial cells. Experimental Lung Research 42:7, pages 335-345.
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Dai-Kun He, Yi-Ru Shao, Lin Zhang, Jie Shen, Zhi-Yue Zhong, Jing Wang & Guoxiong Xu. (2014) Adenovirus-delivered angiopoietin-1 suppresses NF-κB and p38 MAPK and attenuates inflammatory responses in phosgene-induced acute lung injury. Inhalation Toxicology 26:3, pages 185-192.
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Jie Shen, Jing Wang, Yi-Ru Shao, Dai-Kun He, Lin Zhang, Lubna Nadeem & Guoxiong Xu. (2013) Adenovirus-delivered angiopoietin-1 treatment for phosgene-induced acute lung injury. Inhalation Toxicology 25:5, pages 272-279.
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Sarah J Higgins, Kevin C Kain & W Conrad Liles. (2011) Immunopathogenesis of falciparum malaria: implications for adjunctive therapy in the management of severe and cerebral malaria. Expert Review of Anti-infective Therapy 9:9, pages 803-819.
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Articles from other publishers (51)
Dorothea Heuberger, Pedro David Wendel-Garcia, Onur Sazpinar, Mattia Müller, Holger Klein, Bong-Sung Kim, Rea Andermatt, Rolf Erlebach, Reto A. Schuepbach, Philipp K. Buehler, Sascha David & Daniel A. Hofmaenner. (2023) The Angiopoietin-2/Angiopoietin-1 ratio increases early in burn patients and predicts mortality. Cytokine 169, pages 156266.
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Christopher M. SchaferSilvia Martin-AlmedinaKatarzyna Kurylowicz, Neil Dufton, Lourdes Osuna-AlmagroMeng-Ling Wu, Charmain F. JohnsonAarti V. ShahDorian O. HaskardAndrianna BuxtonErika WillisKate WheelerSean TurnerMagdalena ChlebiczRizaldy P. Scott, Susan Kovats, Audrey CleurenGraeme M. Birdsey, Anna M. Randi & Courtney T. Griffin. (2023) Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory Challenge. Arteriosclerosis, Thrombosis, and Vascular Biology 43:8, pages 1412-1428.
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Yoshiyuki Hattori, Hiromu Saito, Kayo Nakamura, Ayaka Yamanaka, Min Tang & Kei-ichi Ozaki. (2022) In vitro and in vivo transfections using siRNA lipoplexes prepared by mixing siRNAs with a lipid-ethanol solution. Journal of Drug Delivery Science and Technology 75, pages 103635.
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Crossref
Gabriele Melegari, Rosina M. Critelli, Simone Lasagni, Dante Romagnoli, Elisabetta Bertellini & Erica Villa. (2022) Dynamic Angiopoietin-2 Serum Level as Endothelial Damage Marker and Potential Therapeutic Target. The American Journal of Pathology 192:9, pages 1336-1337.
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Yoshiyuki Hattori, Min Tang, Satomi Torii, Kana Tomita, Ayane Sagawa, Nodoka Inoue, Reo Yamagishi & Kei-Ichi Ozaki. (2022) Optimal combination of cationic lipid and phospholipid in cationic liposomes for gene knockdown in breast cancer cells and mouse lung using siRNA lipoplexes. Molecular Medicine Reports 26:2.
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Crossref
Xiaohe Li, Ling Ma, Yuli Wei, Jinying Gu, Jingjing Liang, Shimeng Li, Yunyao Cui, Rui Liu, Hui Huang, Cheng Yang & Honggang Zhou. (2021) Cabozantinib ameliorates lipopolysaccharide-induced lung inflammation and bleomycin--induced early pulmonary fibrosis in mice. International Immunopharmacology 101, pages 108327.
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Crossref
Yoshiyuki Hattori, Hiromu Saito, Teruaki Oku & Kei-Ichi Ozaki. (2021) Effects of sterol derivatives in cationic liposomes on biodistribution and gene-knockdown in the lungs of mice systemically injected with siRNA lipoplexes. Molecular Medicine Reports 24:2.
Crossref
Crossref
Erica Villa, Rosina Critelli, Simone Lasagni, Alessandra MelegariAngela CuratoloCiro Celsa, Dante Romagnoli, Gabriele Melegari, Alessandra Pivetti, Lorenza Di Marco, Federico Casari, Dimitriy ArioliFabrizio TurriniValentina ZuccaroIrene Cassaniti, Mattia Riefolo, Elena de SantisVeronica Bernabucci, Marcello Bianchini, Barbara Lei, Nicola De Maria, Lucia Carulli, Filippo Schepis, Chiara GozziSilvio Malaguti, Mariagrazia Del Buono, Lucio Brugioni, Pietro TorricelliTommaso TrentiGiovanni PinelliElisabetta Bertellini, Raffaele Bruno, Calogero Cammà & Antonia d’Errico. (2021) Dynamic angiopoietin-2 assessment predicts survival and chronic course in hospitalized patients with COVID-19. Blood Advances 5:3, pages 662-673.
Crossref
Crossref
Yiru Shao, Zhifeng Jiang, Daikun He & Jie Shen. (2021) Comprehensive Analysis of the Profiles of Differentially Expressed mRNAs, lncRNAs, and circRNAs in Phosgene-Induced Acute Lung Injury. BioMed Research International 2021, pages 1-22.
Crossref
Crossref
Elena V Dolmatova, Keke Wang, Rohan Mandavilli & Kathy K Griendling. (2021) The effects of sepsis on endothelium and clinical implications. Cardiovascular Research 117:1, pages 60-73.
Crossref
Crossref
Alice G. Vassiliou, Anastasia Kotanidou, Ioanna Dimopoulou & Stylianos E. Orfanos. (2020) Endothelial Damage in Acute Respiratory Distress Syndrome. International Journal of Molecular Sciences 21:22, pages 8793.
Crossref
Crossref
Daniëlle MH Beurskens, Martine E Bol, Tammo Delhaas, Marcel CG van de Poll, Chris PM Reutelingsperger, Gerry AF Nicolaes & Jan-Willem EM Sels. (2020) Decreased endothelial glycocalyx thickness is an early predictor of mortality in sepsis. Anaesthesia and Intensive Care 48:3, pages 221-228.
Crossref
Crossref
Yanli Yu, Haibin Fang, Zhen Qiu, Zhongyuan Xia & Bin Zhou. (2019) DHA Attenuates Hypoxia/Reoxygenation Injury by Activating SSeCKS in Human Cerebrovascular Pericytes. Neurochemical Research 45:2, pages 310-321.
Crossref
Crossref
Guanqiao Li, Ulka Sachdev, Kevin Peters, Xiaoyan Liang & Michael T. Lotze. (2019) The VE-PTP Inhibitor AKB-9778 Improves Antitumor Activity and Diminishes the Toxicity of Interleukin 2 (IL-2) Administration. Journal of Immunotherapy 42:7, pages 237-243.
Crossref
Crossref
Yoshiyuki Hattori, Kyoko Tamaki, Kei-ichi Ozaki, Kumi Kawano & Hiraku Onishi. (2019) Optimized combination of cationic lipids and neutral helper lipids in cationic liposomes for siRNA delivery into the lung by intravenous injection of siRNA lipoplexes. Journal of Drug Delivery Science and Technology 52, pages 1042-1050.
Crossref
Crossref
Saiping Jiang, Shujuan Li, Jingbo Hu, Xiaoling Xu, Xiaojuan Wang, Xuqi Kang, Jing Qi, Xiaoyang Lu, Jiahui Wu, Yongzhong Du & Yonghong Xiao. (2019) Combined delivery of angiopoietin-1 gene and simvastatin mediated by anti-intercellular adhesion molecule-1 antibody-conjugated ternary nanoparticles for acute lung injury therapy. Nanomedicine: Nanotechnology, Biology and Medicine 15:1, pages 25-36.
Crossref
Crossref
Sneha Singh, M. G. Anupriya, Ayan Modak & Easwaran Sreekumar. (2018) Dengue virus or NS1 protein induces trans-endothelial cell permeability associated with VE-Cadherin and RhoA phosphorylation in HMEC-1 cells preventable by Angiopoietin-1. Journal of General Virology 99:12, pages 1658-1670.
Crossref
Crossref
Stephen Statz, Giselle Sabal, Amanda Walborn, Mark Williams, Debra Hoppensteadt, Michael Mosier, Matthew Rondina & Jawed Fareed. (2018) Angiopoietin 2 Levels in the Risk Stratification and Mortality Outcome Prediction of Sepsis-Associated Coagulopathy. Clinical and Applied Thrombosis/Hemostasis 24:8, pages 1223-1233.
Crossref
Crossref
Christopher Geven, Andreas Bergmann, Matthijs Kox & Peter Pickkers. (2018) Vascular Effects of Adrenomedullin and the Anti-Adrenomedullin Antibody Adrecizumab in Sepsis. Shock 50:2, pages 132-140.
Crossref
Crossref
Aleksandra Leligdowicz, Melissa Richard-Greenblatt, Julie Wright, Valerie M. Crowley & Kevin C. Kain. (2018) Endothelial Activation: The Ang/Tie Axis in Sepsis. Frontiers in Immunology 9.
Crossref
Crossref
Kenny Schlosser, Mohamad Taha, Yupu Deng, Lauralyn A McIntyre, Shirley H J Mei & Duncan J Stewart. (2018) High circulating angiopoietin-2 levels exacerbate pulmonary inflammation but not vascular leak or mortality in endotoxin-induced lung injury in mice. Thorax 73:3, pages 248-261.
Crossref
Crossref
Krishnapriya Loganathan, Ebtisam Salem Said, Emily Winterrowd, Martina Orebrand, Liqun He, Michael Vanlandewijck, Christer Betsholtz, Susan E. Quaggin & Marie Jeansson. (2018) Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice. PLOS ONE 13:1, pages e0189433.
Crossref
Crossref
Nikita Minhas, Meilang Xue & Christopher J. Jackson. (2016) Activated protein C binds directly to Tie2: possible beneficial effects on endothelial barrier function. Cellular and Molecular Life Sciences 74:10, pages 1895-1906.
Crossref
Crossref
Aleksandra Leligdowicz, Andrea L. Conroy, Michael Hawkes, Kathleen Zhong, Gerald Lebovic, Michael A. Matthay & Kevin C. Kain. (2017) Validation of two multiplex platforms to quantify circulating markers of inflammation and endothelial injury in severe infection. PLOS ONE 12:4, pages e0175130.
Crossref
Crossref
Gerdie M. de Jong, Jasper J. Slager, Annelies Verbon, Jaap J. van Hellemond & Perry J. J. van Genderen. (2016) Systematic review of the role of angiopoietin-1 and angiopoietin-2 in Plasmodium species infections: biomarkers or therapeutic targets?. Malaria Journal 15:1.
Crossref
Crossref
Heming Wang, Brian E. Cade, Han Chen, Kevin J. Gleason, Richa Saxena, Tao Feng, Emma K. Larkin, Ramachandran S. Vasan, Honghuang Lin, Sanjay R. Patel, Russell P. Tracy, Yongmei Liu, Daniel J. Gottlieb, Jennifer E. Below, Craig L. Hanis, Lauren E. Petty, Shamil R. Sunyaev, Alexis C. Frazier-Wood, Jerome I. Rotter, Wendy Post, Xihong Lin, Susan Redline & Xiaofeng Zhu. (2016)
Variants in angiopoietin-2 (
ANGPT2
) contribute to variation in nocturnal oxyhaemoglobin saturation level
. Human Molecular Genetics, pages ddw324.
Crossref
Crossref
Matt S. Zinter, Aaron Spicer, Benjamin O. Orwoll, Mustafa Alkhouli, Christopher C. Dvorak, Carolyn S. Calfee, Michael A. Matthay & Anil Sapru. (2016) Plasma angiopoietin-2 outperforms other markers of endothelial injury in prognosticating pediatric ARDS mortality. American Journal of Physiology-Lung Cellular and Molecular Physiology 310:3, pages L224-L231.
Crossref
Crossref
Karol Bomsztyk, Daniel Mar, Dowon An, Roya Sharifian, Michal Mikula, Sina A Gharib, William A Altemeier, W Conrad Liles & Oleg Denisenko. (2015) Experimental acute lung injury induces multi-organ epigenetic modifications in key angiogenic genes implicated in sepsis-associated endothelial dysfunction. Critical Care 19:1.
Crossref
Crossref
Di-min Nie, Qiu-ling Wu, Xia-xia Zhu, Ran Zhang, Peng Zheng, Jun Fang, Yong You, Zhao-dong Zhong, Ling-hui Xia & Mei Hong. (2015) Angiogenic factors are associated with development of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Journal of Huazhong University of Science and Technology [Medical Sciences] 35:5, pages 694-699.
Crossref
Crossref
Wei Zheng, Harri Nurmi, Sila Appak, Amélie Sabine, Esther Bovay, Emilia A. Korhonen, Fabrizio Orsenigo, Marja Lohela, Gabriela D’Amico, Tanja Holopainen, Ching Ching Leow, Elisabetta Dejana, Tatiana V. Petrova, Hellmut G. Augustin & Kari Alitalo. (2014) Angiopoietin 2 regulates the transformation and integrity of lymphatic endothelial cell junctions. Genes & Development 28:14, pages 1592-1603.
Crossref
Crossref
John P. Reilly, Scarlett Bellamy, Michael G. S. Shashaty, Robert Gallop, Nuala J. Meyer, Paul N. Lanken, Sandra Kaplan, Daniel N. Holena, Addison K. May, Lorraine B. Ware & Jason D. Christie. (2014) Heterogeneous Phenotypes of Acute Respiratory Distress Syndrome after Major Trauma. Annals of the American Thoracic Society 11:5, pages 728-736.
Crossref
Crossref
V Fehring, U Schaeper, K Ahrens, A Santel, O Keil, M Eisermann, K Giese & Jörg Kaufmann. (2014) Delivery of Therapeutic siRNA to the Lung Endothelium via Novel Lipoplex Formulation DACC. Molecular Therapy 22:4, pages 811-820.
Crossref
Crossref
Alexandra Binnie, Jennifer L.Y. Tsang & Claudia C. dos Santos. (2014) Biomarkers in acute respiratory distress syndrome. Current Opinion in Critical Care 20:1, pages 47-55.
Crossref
Crossref
Lauri Eklund & Pipsa Saharinen. (2013) Angiopoietin signaling in the vasculature. Experimental Cell Research 319:9, pages 1271-1280.
Crossref
Crossref
Prashant Chittiboina, Vijay Ganta, Christopher P. Monceaux, L. Keith Scott, Anil Nanda & J. Steven Alexander. (2013) Angiopoietins as promising biomarkers and potential therapeutic targets in brain injury. Pathophysiology 20:1, pages 15-21.
Crossref
Crossref
Geerten P. van Nieuw Amerongen. 2013. Mechanical and Chemical Signaling in Angiogenesis. Mechanical and Chemical Signaling in Angiogenesis
211
226
.
Claudia C. dos Santos, Srinivas Murthy, Pingzhao Hu, Yuexin Shan, Jack J. Haitsma, Shirley H.J. Mei, Duncan J. Stewart & W. Conrad Liles. (2012) Network Analysis of Transcriptional Responses Induced by Mesenchymal Stem Cell Treatment of Experimental Sepsis. The American Journal of Pathology 181:5, pages 1681-1692.
Crossref
Crossref
Rajesh S. AlphonseSaima RajabaliBernard Thébaud. (2012) Lung Injury in Preterm Neonates: The Role and Therapeutic Potential of Stem Cells. Antioxidants & Redox Signaling 17:7, pages 1013-1040.
Crossref
Crossref
Rafael A. CoutoAnn M. KulungowskiAditya S. ChawlaSteven J. FishmanArin K. Greene. (2011) Expression of Angiogenic and Vasculogenic Factors in Human Lymphedematous Tissue. Lymphatic Research and Biology 9:3, pages 143-149.
Crossref
Crossref
Sascha David, Joon-Keun Park, Matijs van Meurs, Jan G. Zijlstra, Christian Koenecke, Claudia Schrimpf, Nelli Shushakova, Faikah Gueler, Hermann Haller & Philipp Kümpers. (2011) Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis. Cytokine 55:2, pages 251-259.
Crossref
Crossref
Ying-Gang Zhu, Jie-Ming Qu, Jing Zhang, Hong-Ni Jiang & Jin-Fu Xu. (2011) Novel Interventional Approaches for ALI/ARDS: Cell-Based Gene Therapy. Mediators of Inflammation 2011, pages 1-7.
Crossref
Crossref
Maria A. Hegeman, Marije P. Hennus, Matijs van Meurs, Pieter M. Cobelens, Annemieke Kavelaars, Nicolaas J. Jansen, Marcus J. Schultz, Adrianus J. van Vught, Grietje Molema & Cobi J. Heijnen. (2010) Angiopoietin-1 Treatment Reduces Inflammation but Does Not Prevent Ventilator-Induced Lung Injury. PLoS ONE 5:12, pages e15653.
Crossref
Crossref
Andreas PetryMichael WeitnauerAgnes Görlach. (2010) Receptor Activation of NADPH Oxidases. Antioxidants & Redox Signaling 13:4, pages 467-487.
Crossref
Crossref
F.-R. E. Curry & R. H. Adamson. (2010) Vascular permeability modulation at the cell, microvessel, or whole organ level: towards closing gaps in our knowledge. Cardiovascular Research 87:2, pages 218-229.
Crossref
Crossref
Jingzhou Chen, Hui Yu, Kai Sun, Weihua Song, Yongyi Bai, Tao Yang, Yan Song, Yinhui Zhang & Rutai Hui. (2010) Promoter variant of angiopoietin-2 and plasma angiopoietin-2 are associated with risk of stroke recurrence in lacunar infarct patients. Biochemical and Biophysical Research Communications 398:2, pages 212-216.
Crossref
Crossref
Vijay C. Ganta, Walter Cromer, Ginny L. Mills, James Traylor, Merilyn Jennings, Sarah Daley, Benjamin Clark, Michael J. Mathis, Michael Bernas, Moheb Boktor, Paul Jordan, Marlys Witte & Steven J. Alexander. (2010) Angiopoietin-2 in experimental colitis. Inflammatory Bowel Diseases 16:6, pages 1029-1039.
Crossref
Crossref
Melanie van der Heijden, Geerten P. van Nieuw Amerongen, Victor W.M. van Hinsbergh & AB Johan Groeneveld. (2010) THE INTERACTION OF SOLUBLE TIE2 WITH ANGIOPOIETINS AND PULMONARY VASCULAR PERMEABILITY IN SEPTIC AND NONSEPTIC CRITICALLY ILL PATIENTS. Shock 33:3, pages 263-268.
Crossref
Crossref
John M. Harlan. 2010. Endothelial Dysfunction and Inflammation. Endothelial Dysfunction and Inflammation
1
13
.
Melanie van der Heijden, Peter Pickkers, Geerten P. van Nieuw Amerongen, Victor W. M. van Hinsbergh, Martijn P. W. J. M. Bouw, Johannes G. van der Hoeven & A. B. Johan Groeneveld. (2009) Circulating angiopoietin-2 levels in the course of septic shock: relation with fluid balance, pulmonary dysfunction and mortality. Intensive Care Medicine 35:9, pages 1567-1574.
Crossref
Crossref
P. He. (2009) Beyond tie-ing up endothelial adhesion: new insights into the action of angiopoietin-1 in regulation of microvessel permeability. Cardiovascular Research 83:1, pages 1-2.
Crossref
Crossref
John S GiulianoJrJr & Derek S Wheeler. (2009) Excess circulating angiopoietin-2 levels in sepsis: harbinger of death in the intensive care unit?. Critical Care 13:1.
Crossref
Crossref