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Julia Jellusova & Robert C. Rickert. (2016) The PI3K pathway in B cell metabolism. Critical Reviews in Biochemistry and Molecular Biology 51:5, pages 359-378.
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Articles from other publishers (112)
Piao Luo, Qian Zhang, Shuo Shen, Yehai An, Lixia Yuan, Yin-Kwan Wong, Sizhe Huang, Shaohui Huang, Jingnan Huang, Guangqing Cheng, Jiahang Tian, Yu Chen, Xiaoyong Zhang, Weiguang Li, Songqi He, Jigang Wang & Qingfeng Du. (2023) Mechanistic engineering of celastrol liposomes induces ferroptosis and apoptosis by directly targeting VDAC2 in hepatocellular carcinoma. Asian Journal of Pharmaceutical Sciences 18:6, pages 100874.
Crossref
Crossref
Shabnam Heydarzadeh, Ali Asghar Moshtaghie, Maryam Daneshpour & Mehdi Hedayati. (2023) The effect of Apigenin on glycometabolism and cell death in an anaplastic thyroid cancer cell line. Toxicology and Applied Pharmacology 475, pages 116626.
Crossref
Crossref
Rilan Bai, Ying Meng & Jiuwei Cui. (2023) Therapeutic strategies targeting metabolic characteristics of cancer cells. Critical Reviews in Oncology/Hematology 187, pages 104037.
Crossref
Crossref
Varda Shoshan-Barmatz, Tasleem Arif & Anna Shteinfer-Kuzmine. (2023) Apoptotic proteins with non-apoptotic activity: expression and function in cancer. Apoptosis 28:5-6, pages 730-753.
Crossref
Crossref
Yuhan Sun, He Zhang, Guangzhao Lu, Huan Wang, Ying Lu & Li Fan. (2023) Mitochondria-targeted cancer therapy based on functional peptides. Chinese Chemical Letters 34:5, pages 107817.
Crossref
Crossref
Mohammad Waseem & Bi-Dar Wang. (2023) Promising Strategy of mPTP Modulation in Cancer Therapy: An Emerging Progress and Future Insight. International Journal of Molecular Sciences 24:6, pages 5564.
Crossref
Crossref
Jing Fang, Shudi Luo & Zhimin Lu. (2023) HK2: Gatekeeping microglial activity by tuning glucose metabolism and mitochondrial functions. Molecular Cell 83:6, pages 829-831.
Crossref
Crossref
Alena Mazurakova, Lenka Koklesova, Sandra Hurta Csizmár, Marek Samec, Aranka Brockmueller, Miroslava Šudomová, Kamil Biringer, Erik Kudela, Martin Pec, Samson Mathews Samuel, Monika Kassayova, Sherif T.S. Hassan, Karel Smejkal, Mehdi Shakibaei, Dietrich Büsselberg, Luciano Saso, Peter Kubatka & Olga Golubnitschaja. (2023) Significance of flavonoids targeting PI3K/Akt/HIF-1α signaling pathway in therapy-resistant cancer cells – A potential contribution to the predictive, preventive, and personalized medicine. Journal of Advanced Research.
Crossref
Crossref
Dong Guo, Ying Meng, Xiaoming Jiang & Zhimin Lu. (2023) Hexokinases in cancer and other pathologies. Cell Insight 2:1, pages 100077.
Crossref
Crossref
Nengyuan Lv, Siyi Shen, Qianying Chen & Jinyi Tong. (2023) Long noncoding RNAs: glycolysis regulators in gynaecologic cancers. Cancer Cell International 23:1.
Crossref
Crossref
Chang Liu, Changfeng Li & Yuanda Liu. (2023) The role of metabolic reprogramming in pancreatic cancer chemoresistance. Frontiers in Pharmacology 13.
Crossref
Crossref
Muhammad Akram, Hina Anwar, Fahad Said Khan, Shamaila Kausar, Sabira Sultana, Gaweł Sołowski, Walaa Fikry Elbossaty & Mourad Ben Said. 2022. Handbook of Cancer and Immunology. Handbook of Cancer and Immunology
1
12
.
Tao Guo, Shihao Peng, Defeng Liu & Yangyang Li. (2022) Long Non-coding RNA LOXL1-AS1 Facilitates Colorectal Cancer Progression via Regulating miR-1224-5p/miR-761/HK2 Axis. Biochemical Genetics 60:6, pages 2416-2433.
Crossref
Crossref
Adriana Romo-Perez, Guadalupe Dominguez-Gomez, Alma Chavez-Blanco, Lucia Taja-Chayeb, Aurora Gonzalez-Fierro, Consuelo Diaz-Romero, Horacio Noe Lopez-Basave & Alfonso Duenas-Gonzalez. (2022) Progress in Metabolic Studies of Gastric Cancer and Therapeutic Implications. Current Cancer Drug Targets 22:9, pages 703-716.
Crossref
Crossref
Lin Mei, Yunjie Chen, Peng Chen, Huinan Chen, Shengqu He, Cheng Jin, Yang Wang, Zhicheng Hu, Wanqian Li, Litai Jin, Weitao Cong, Xu Wang & Xueqiang Guan. (2022) Fibroblast growth factor 7 alleviates myocardial infarction by improving oxidative stress via PI3Kα/AKT-mediated regulation of Nrf2 and HXK2. Redox Biology 56, pages 102468.
Crossref
Crossref
Jia Jin, Ailing Gui, Guangliang Chen, Yizhen Liu, Zuguang Xia, Xiaojian Liu, Fangfang Lv, Junning Cao, Xiaonan Hong, Ling Yang, Juan J. Gu & Qunling Zhang. (2022) Hexokinase II expression as a prognostic marker in diffuse large B-cell lymphoma: pre- and post-rituximab era. International Journal of Hematology 116:3, pages 372-380.
Crossref
Crossref
Dingde Long, Xingjun Fang, Peihua Yuan, Liqin Cheng, Hongtao Li & LiangChao Qu. (2022) Lidocaine promotes apoptosis in breast cancer cells by affecting VDAC1 expression. BMC Anesthesiology 22:1.
Crossref
Crossref
Linlin Lv, Shilei Yang, Yanna Zhu, Xiaohan Zhai, Shuai Li, Xufeng Tao & Deshi Dong. (2022) Relationship between metabolic reprogramming and drug resistance in breast cancer. Frontiers in Oncology 12.
Crossref
Crossref
Yuting Chen, Hui Yang, Shaoyun Chen, Zhaohong Lu, Boxin Li, Tikeng Jiang, Mei Xuan, Ruifang Ye, Hairong Liang, Xiaoshan Liu, Qizhan Liu & Huanwen Tang. (2022) SIRT1 regulated hexokinase-2 promoting glycolysis is involved in hydroquinone-enhanced malignant progression in human lymphoblastoid TK6 cells. Ecotoxicology and Environmental Safety 241, pages 113757.
Crossref
Crossref
Jiachen Li, Jianmin Pan, Yang Liu, Xiaohui Luo, Cheng Yang, Wangfa Xiao, Qishang Li, Lihui Yang & Xiaodong Zhang. (2022) 3‑Bromopyruvic acid regulates glucose metabolism by targeting the c‑Myc/TXNIP axis and induces mitochondria‑mediated apoptosis in TNBC cells. Experimental and Therapeutic Medicine 24:2.
Crossref
Crossref
Thaís Oliveira, Douglas Lemos, Louise Jean, Jéssica M. Kawashima, Vitória R. de Azevedo, Eduardo J. Salustiano, Vivian M. Rumjanek & Robson Q. Monteiro. (2022) Detachment of Hexokinase II From Mitochondria Promotes Collateral Sensitivity in Multidrug Resistant Chronic Myeloid Leukemia Cells. Frontiers in Oncology 12.
Crossref
Crossref
Entaz Bahar, Sun-Young Han, Ji-Ye Kim & Hyonok Yoon. (2022) Chemotherapy Resistance: Role of Mitochondrial and Autophagic Components. Cancers 14:6, pages 1462.
Crossref
Crossref
Ibrahim Damilare Boyenle, Abdulquddus Kehinde Oyedele, Abdeen Tunde Ogunlana, Aishat Folashade Adeyemo, Faith Sunday Oyelere, Olateju Balikis Akinola, Temitope Isaac Adelusi, Leonard Ona Ehigie & Adeola Folasade Ehigie. (2022) Targeting the mitochondrial permeability transition pore for drug discovery: Challenges and opportunities. Mitochondrion 63, pages 57-71.
Crossref
Crossref
Karolina Juszczak, Anna Kubicka, Radosław Kitel, Grzegorz Dzido, Magdalena Łabieniec-Watała, Serafin Zawadzki, Agnieszka Marczak, Krzysztof Walczak, Karolina Matczak & Mateusz D. Tomczyk. (2022) Hexokinase 2 Inhibition and Biological Effects of BNBZ and Its Derivatives: The Influence of the Number and Arrangement of Hydroxyl Groups. International Journal of Molecular Sciences 23:5, pages 2616.
Crossref
Crossref
Minghuan Gao, Yuying Yang, Ying Gao, Tong Liu, Qi Guan, Tianhao Zhou, Yani Shi, Mingjing Hao, Zengqiang Li, Daiying Zuo, Weige Zhang & Yingliang Wu. (2022) The anti-MDR efficacy of YAN against A549/Taxol cells is associated with its inhibition on glycolysis and is further enhanced by 2-deoxy-d-glucose. Chemico-Biological Interactions 354, pages 109843.
Crossref
Crossref
Qi Wu, Shao-Ping Wang, Xiao-Xue Sun, Yu-Fan Tao, Xiao-Qing Yuan, Qi-Mei Chen, Long Dai, Chun-Lei Li, Jia-Yu Zhang & Ai-Lin Yang. (2022) HuaChanSu suppresses tumor growth and interferes with glucose metabolism in hepatocellular carcinoma cells by restraining Hexokinase-2. The International Journal of Biochemistry & Cell Biology 142, pages 106123.
Crossref
Crossref
Jiexin Wen, Yong Luo, Hui Gao, Liang Zhang, Xiang Wang, Ju Huang, Tingting Shang, Di Zhou, Dong Wang, Zhigang Wang, Pan Li & Zhaoxia Wang. (2021) Mitochondria-targeted nanoplatforms for enhanced photodynamic therapy against hypoxia tumor. Journal of Nanobiotechnology 19:1.
Crossref
Crossref
Dan Liu, Xiaowen Zhou, Sen Wang, Tingting Dai, Lixia Luo, Qing Ning, Bojia Liu, Ziyu Jiang, Nan Yao, Yi Luo & Jie Song. (2021) Ethanol extracts of Balanophora laxiflora Hemsl inhibit hepatocellular carcinoma with the involvement of HKII-mediated glycolysis. Journal of Functional Foods 87, pages 104782.
Crossref
Crossref
Shine-Gwo Shiah, Sung-Tau Chou & Jang-Yang Chang. (2021) MicroRNAs: Their Role in Metabolism, Tumor Microenvironment, and Therapeutic Implications in Head and Neck Squamous Cell Carcinoma. Cancers 13:22, pages 5604.
Crossref
Crossref
Aude Angelini, Pradip K. Saha, Antrix Jain, Sung Yun Jung, Randall L. Mynatt, Xinchun Pi & Liang Xie. (2021) PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes. Cell Reports 37:1, pages 109767.
Crossref
Crossref
Chang Liu, Ying Jin & Zhimin Fan. (2021) The Mechanism of Warburg Effect-Induced Chemoresistance in Cancer. Frontiers in Oncology 11.
Crossref
Crossref
Irene Bagaloni, Axel Visani, Sara Biagiotti, Annamaria Ruzzo, Mohsen Navari, Maryam Etebari, Lucia Mundo, Massimo Granai, Stefano Lazzi, Alessandro Isidori, Federica Loscocco, Jiejin Li, Lorenzo Leoncini, Giuseppe Visani, Mauro Magnani & Pier Paolo Piccaluga. (2021) Metabolic Switch and Cytotoxic Effect of Metformin on Burkitt Lymphoma. Frontiers in Oncology 11.
Crossref
Crossref
Nandan Haloi, Po-Chao Wen, Qunli Cheng, Meiying Yang, Gayathri Natarajan, Amadou K. S. Camara, Wai-Meng Kwok & Emad Tajkhorshid. (2021) Structural basis of complex formation between mitochondrial anion channel VDAC1 and Hexokinase-II. Communications Biology 4:1.
Crossref
Crossref
Chaonan Jin, Pavitra Kumar, Jordi Gracia‐Sancho & Jean‐François Dufour. (2021) Calcium transfer between endoplasmic reticulum and mitochondria in liver diseases. FEBS Letters 595:10, pages 1411-1421.
Crossref
Crossref
Manzoor A. Mir, Umar Mehraj & Bashir A. Sheikh. (2021) Recent Advances in Chemotherapeutic Implications of Deguelin: A Plant- Derived Retinoid. The Natural Products Journal 11:2, pages 169-181.
Crossref
Crossref
Qiaojing ShiTao JiZhongxia MaQiang TanJiangshui Liang. (2021)
Serum Exosomes-Based Biomarker circ_0008928 Regulates Cisplatin Sensitivity, Tumor Progression, and Glycolysis Metabolism by miR-488/
HK2
Axis in Cisplatin-Resistant Nonsmall Cell Lung Carcinoma
. Cancer Biotherapy and Radiopharmaceuticals.
Crossref
Crossref
Hui Yi, Xiaokai Shen, Haiqin Wang, Saiqun Luo, Wancheng Guo, Peng Chen, Lei Hu, Long Liang, Yanfei Gong, Xiaojuan Xiao & Jing Liu. (2021) Protein mass spectrometry reveals lycorine exerting anti-multiple-myeloma effect by acting on VDAC2 and causing mitochondrial abnormalities. Biotechnology Letters 43:3, pages 537-546.
Crossref
Crossref
Asiyeh Jebelli, Behzad Baradaran, Jafar Mosafer, Amir Baghbanzadeh, Ahad Mokhtarzadeh & Lobat Tayebi. (2020) Recent developments in targeting genes and pathways by RNAi‐based approaches in colorectal cancer. Medicinal Research Reviews 41:1, pages 395-434.
Crossref
Crossref
Meng Zhang, Qiyu Liu, Mingxing Zhang, Cong Cao, Xiaoxia Liu, Mengyu Zhang, Guiling Li, Congjian Xu & Xiaoyan Zhang. (2020) Enhanced antitumor effects of follicle-stimulating hormone receptor-mediated hexokinase-2 depletion on ovarian cancer mediated by a shift in glucose metabolism. Journal of Nanobiotechnology 18:1.
Crossref
Crossref
Monique Meyenberg Cunha-de Padua, Lucilla Fabbri, Maeva Dufies, Sandra Lacas-Gervais, Julie Contenti, Charles Voyton, Sofia Fazio, Marie Irondelle, Baharia Mograbi, Matthieu Rouleau, Nirvana Sadaghianloo, Amandine Rovini, Catherine Brenner, William J. Craigen, Jérôme Bourgeais, Olivier Herault, Frédéric Bost & Nathalie M. Mazure. (2020) Evidences of a Direct Relationship between Cellular Fuel Supply and Ciliogenesis Regulated by Hypoxic VDAC1-ΔC. Cancers 12:11, pages 3484.
Crossref
Crossref
Rui Zhang, Weiyong Shen, Jianhai Du & Mark C. Gillies. (2020) Selective knockdown of hexokinase 2 in rods leads to age-related photoreceptor degeneration and retinal metabolic remodeling. Cell Death & Disease 11:10.
Crossref
Crossref
Vaishali Chandel, Sibi Raj, Prabhat Kumar, Shilpi Gupta, Anupam Dhasmana, Kavindra Kumar Kesari, Janne Ruokolainen, Pravesh Mehra, Bhudev C. Das, Mohammad Amjad Kamal & Dhruv Kumar. (2020) Metabolic regulation in HPV associated head and neck squamous cell carcinoma. Life Sciences 258, pages 118236.
Crossref
Crossref
Ashlesha Kadam, Tina Jubin, Rittwika Roychowdhury & Rasheedunnisa Begum. (2020) Role of PARP-1 in mitochondrial homeostasis. Biochimica et Biophysica Acta (BBA) - General Subjects 1864:10, pages 129669.
Crossref
Crossref
Ruilong Li & Weidong Yang. (2020) Gomisin J inhibits the glioma progression by inducing apoptosis and reducing HKII-regulated glycolysis. Biochemical and Biophysical Research Communications 529:1, pages 15-22.
Crossref
Crossref
Youjun Zhang & Alisdair Fernie. (2020) On the Detection and Functional Significance of the Protein–Protein Interactions of Mitochondrial Transport Proteins. Biomolecules 10:8, pages 1107.
Crossref
Crossref
Xiu‐Mei Zhang, Ai‐Hong Peng, Wei‐Dong Xie, Mei Wang, Dan Zheng & Ming‐Kuan Feng. (2020)
Hexokinase II Inhibitory Effect of Secondary Metabolites Derived from a
Streptomyces
sp. Associated with Mud Dauber Wasp
. Chemistry & Biodiversity 17:7.
Crossref
Crossref
Wenwu DuNing LiuYafeng ZhangXi LiuYuanhong YangWei ChenYi He. (2020) PLOD2 promotes aerobic glycolysis and cell progression in colorectal cancer by upregulating HK2. Biochemistry and Cell Biology 98:3, pages 386-395.
Crossref
Crossref
Qi-qi Wang, Ming-xue Li, Chen Li, Xiao-xia Gu, Meng-zhu Zheng, Li-xia Chen & Hua Li. (2020) Natural Products and Derivatives Targeting at Cancer Energy Metabolism: A Potential Treatment Strategy. Current Medical Science 40:2, pages 205-217.
Crossref
Crossref
Mengmeng Li, Jiangjuan Shao, Zijian Guo, Chun Jin, Ling Wang, Feixia Wang, Yan Jia, Zhenzhu Zhu, Ziji Zhang, Feng Zhang, Shizhong Zheng & Xiaoyong Wang. (2020) Novel mitochondrion‐targeting copper(II) complex induces HK2 malfunction and inhibits glycolysis via Drp1‐mediating mitophagy in HCC. Journal of Cellular and Molecular Medicine 24:5, pages 3091-3107.
Crossref
Crossref
Chetan Malik & Subhendu Ghosh. (2020) Quinidine partially blocks mitochondrial voltage-dependent anion channel (VDAC). European Biophysics Journal 49:2, pages 193-205.
Crossref
Crossref
Sara N. Garcia, Rita C. Guedes & M. Matilde Marques. (2020) Unlocking the Potential of HK2 in Cancer Metabolism and Therapeutics. Current Medicinal Chemistry 26:41, pages 7285-7322.
Crossref
Crossref
Xiaochun Wang, Reichelle X. Yeo, Philip J. Hogg, David Goldstein, Philip Crowe, Pierre J. Dilda & Jia-Lin Yang. (2020) The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas. Oncotarget 11:1, pages 46-61.
Crossref
Crossref
Luigi Leanza, Vanessa Checchetto, Lucia Biasutto, Andrea Rossa, Roberto Costa, Magdalena Bachmann, Mario Zoratti & Ildiko Szabo. (2019) Pharmacological modulation of mitochondrial ion channels. British Journal of Pharmacology 176:22, pages 4258-4283.
Crossref
Crossref
V. A. Kobliakov. (2019) The Mechanisms of Regulation of Aerobic Glycolysis (Warburg Effect) by Oncoproteins in Carcinogenesis. Biochemistry (Moscow) 84:10, pages 1117-1128.
Crossref
Crossref
Yogesh Rai, Priyanshu Yadav, Neeraj Kumari, Namita Kalra & Anant Narayan Bhatt. (2019) Hexokinase II inhibition by 3-bromopyruvate sensitizes myeloid leukemic cells K-562 to anti-leukemic drug, daunorubicin. Bioscience Reports 39:9.
Crossref
Crossref
Dan Liu, Angelina Angelova, Jianwen Liu, Vasil M. Garamus, Borislav Angelov, Xinlei Zhang, Yawen Li, Guillaume Feger, Na Li & Aihua Zou. (2019) Self-assembly of mitochondria-specific peptide amphiphiles amplifying lung cancer cell death through targeting the VDAC1–hexokinase-II complex. Journal of Materials Chemistry B 7:30, pages 4706-4716.
Crossref
Crossref
Hang Li, Shaohong Lu, Yu Chen, Longzhi Zheng, Liangyuan Chen, Haojie Ding, Jianzu Ding, Di Lou, Fangfang Liu & Bin Zheng. (2019) AKT2 phosphorylation of hexokinase 2 at T473 promotes tumorigenesis and metastasis in colon cancer cells via NF-κB, HIF1α, MMP2, and MMP9 upregulation. Cellular Signalling 58, pages 99-110.
Crossref
Crossref
Hongyan Wu, Lanlan Pan, Cuixiang Gao, Hongtao Xu, Yanping Li, Lihu Zhang, Linwei Ma, Li Meng, Xiulan Sun & Hongbing Qin. (2019) Quercetin Inhibits the Proliferation of Glycolysis-Addicted HCC Cells by Reducing Hexokinase 2 and Akt-mTOR Pathway. Molecules 24:10, pages 1993.
Crossref
Crossref
Hang Yang, Jiang-Tao Zhong, Shui-Hong Zhou & He-Ming Han. (2019) Roles of GLUT-1 and HK-II expression in the biological behavior of head and neck cancer. Oncotarget 10:32, pages 3066-3083.
Crossref
Crossref
Xiaoli Chen, Yang Lv, Ying Sun, Hongyu Zhang, Weiguo Xie, Liyan Zhong, Qi Chen, Min Li, Ling Li, Jia Feng, Athena Yao, Qi Zhang, Xiaodong Huang, Zhendong Yu & Paul Yao. (2019) PGC1β Regulates Breast Tumor Growth and Metastasis by SREBP1-Mediated HKDC1 Expression. Frontiers in Oncology 9.
Crossref
Crossref
Maria S. Fedorova, George S. Krasnov, Elena N. Lukyanova, Andrew R. Zaretsky, Alexey A. Dmitriev, Nataliya V. Melnikova, Alexey A. Moskalev, Sergey L. Kharitonov, Elena A. Pudova, Zulfiya G. Guvatova, Anastasiya A. Kobelyatskaya, Irina A. Ishina, Elena N. Slavnova, Anastasia V. Lipatova, Maria A. Chernichenko, Dmitry V. Sidorov, Anatoly Y. Popov, Marina V. Kiseleva, Andrey D. Kaprin, Anastasiya V. Snezhkina & Anna V. Kudryavtseva. (2019) The CIMP-high phenotype is associated with energy metabolism alterations in colon adenocarcinoma. BMC Medical Genetics 20:S1.
Crossref
Crossref
Andrew J. McDonald, Katherine M. Curt, Ruchi P. Patel, Hanna Kozlowski, Dan L. Sackett, Robert W. Robey, Michael M. Gottesman & Susan E. Bates. (2019) Targeting mitochondrial hexokinases increases efficacy of histone deacetylase inhibitors in solid tumor models. Experimental Cell Research 375:2, pages 106-112.
Crossref
Crossref
Chunyan Liu, Xiuli Wang & Youzhong Zhang. (2019) The Roles of HK2 on Tumorigenesis of Cervical Cancer. Technology in Cancer Research & Treatment 18, pages 153303381987130.
Crossref
Crossref
Mengzhu Zheng, Lixia Chen & Li Hua. 2019. In Silico Drug Design. In Silico Drug Design
527
548
.
Tasleem Arif, Avijit Paul, Yakov Krelin, Anna Shteinfer-Kuzmine & Varda Shoshan-Barmatz. (2018) Mitochondrial VDAC1 Silencing Leads to Metabolic Rewiring and the Reprogramming of Tumour Cells into Advanced Differentiated States. Cancers 10:12, pages 499.
Crossref
Crossref
Vered Behar, Hadas Pahima, Adi Kozminsky-Atias, Nir Arbel, Emmanuel Loeb, Max Herzberg & Oren M. Becker. (2018) A Hexokinase 2 Modulator for Field-Directed Treatment of Experimental Actinic Keratoses. Journal of Investigative Dermatology 138:12, pages 2635-2643.
Crossref
Crossref
Bo Liu & Shuo Yu. (2018) RETRACTED: Amentoflavone suppresses hepatocellular carcinoma by repressing hexokinase 2 expression through inhibiting JAK2/STAT3 signaling. Biomedicine & Pharmacotherapy 107, pages 243-253.
Crossref
Crossref
Chae Young Han, David A. Patten, Richard B. Richardson, Mary-Ellen Harper & Benjamin K. Tsang. (2018) Tumor metabolism regulating chemosensitivity in ovarian cancer. Genes & Cancer 9:5-6, pages 155-175.
Crossref
Crossref
Qiang Wang, Yi Yan, Jie Zhang, Peng Guo, Yuqing Xing, Yong Wang, Fawei Qin & Qingyun Zeng. (2018) RETRACTED: Physcion 8-O-β-glucopyranoside inhibits clear-cell renal cell carcinoma bydownregulating hexokinase II and inhibiting glycolysis. Biomedicine & Pharmacotherapy 104, pages 28-35.
Crossref
Crossref
Srinivas Pittala, Yakov Krelin & Varda Shoshan-Barmatz. (2018) Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide. Neoplasia 20:6, pages 594-609.
Crossref
Crossref
Anna Shteinfer‐Kuzmine, Zohar Amsalem, Tasleem Arif, Alexandra Zooravlov & Varda Shoshan‐Barmatz. (2018)
Selective induction of cancer cell death by
VDAC
1‐based peptides and their potential use in cancer therapy
. Molecular Oncology 12:7, pages 1077-1103.
Crossref
Crossref
A. V. Snezhkina, G. S. Krasnov, S. O. Zhikrivetskaya, I. Y. Karpova, M. S. Fedorova, K. M. Nyushko, M. M. Belyakov, N. V. Gnuchev, D. V. Sidorov, B. Y. Alekseev, N. V. Melnikova & A. V. Kudryavtseva. (2018) Overexpression of microRNAs miR-9, -98, and -199 Correlates with the Downregulation of HK2 Expression in Colorectal Cancer. Molecular Biology 52:2, pages 190-199.
Crossref
Crossref
Fengyan Bao, Kaiyin Yang, Canrong Wu, Suyu Gao, Penghe Wang, Lixia Chen & Hua Li. (2018) New natural inhibitors of hexokinase 2 (HK2): Steroids from Ganoderma sinense. Fitoterapia 125, pages 123-129.
Crossref
Crossref
Elena A. Pudova, Anna V. Kudryavtseva, Maria S. Fedorova, Andrew R. Zaretsky, Dmitry S. Shcherbo, Elena N. Lukyanova, Anatoly Y. Popov, Asiya F. Sadritdinova, Ivan S. Abramov, Sergey L. Kharitonov, George S. Krasnov, Kseniya M. Klimina, Nadezhda V. Koroban, Nadezhda N. Volchenko, Kirill M. Nyushko, Nataliya V. Melnikova, Maria A. Chernichenko, Dmitry V. Sidorov, Boris Y. Alekseev, Marina V. Kiseleva, Andrey D. Kaprin, Alexey A. Dmitriev & Anastasiya V. Snezhkina. (2018) HK3 overexpression associated with epithelial-mesenchymal transition in colorectal cancer. BMC Genomics 19:S3.
Crossref
Crossref
Xiao-Yan Zhang, Meng Zhang, Qing Cong, Ming-Xing Zhang, Meng-Yu Zhang, Ying-Ying Lu & Cong-Jian Xu. (2018) Hexokinase 2 confers resistance to cisplatin in ovarian cancer cells by enhancing cisplatin-induced autophagy. The International Journal of Biochemistry & Cell Biology 95, pages 9-16.
Crossref
Crossref
Juan J. Gu, Anil Singh, Kai Xue, Cory Mavis, Matthew Barth, Vivek Yanamadala, Peter Lenz, Michael Grau, Georg Lenz, Myron S. Czuczman & Francisco J. Hernandez-Ilizaliturri. (2017) Up-regulation of hexokinase II contributes to rituximab-chemotherapy resistance and is a clinically relevant target for therapeutic development. Oncotarget 9:3, pages 4020-4033.
Crossref
Crossref
Karin Hoppe-Seyler, Anja Honegger, Felicitas Bossler, Jasmin Sponagel, Julia Bulkescher, Claudia Lohrey & Felix Hoppe-Seyler. (2017)
Viral
E6/E7
oncogene and cellular hexokinase 2 expression in HPV-positive cancer cell lines
. Oncotarget 8:63, pages 106342-106351.
Crossref
Crossref
Wei Li, Mengzhu Zheng, Shuangping Wu, Suyu Gao, Mei Yang, Zhimei Li, Qiuxia Min, Weiguang Sun, Lixia Chen, Guangya Xiang & Hua Li. (2017) Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2. Journal of Experimental & Clinical Cancer Research 36:1.
Crossref
Crossref
Maria S. Fedorova, Anastasiya V. Snezhkina, Elena A. Pudova, Ivan S. Abramov, Anastasiya V. Lipatova, Sergey L. Kharitonov, Asiya F. Sadritdinova, Kirill M. Nyushko, Kseniya M. Klimina, Mikhail M. Belyakov, Elena N. Slavnova, Nataliya V. Melnikova, Maria A. Chernichenko, Dmitry V. Sidorov, Marina V. Kiseleva, Andrey D. Kaprin, Boris Y. Alekseev, Alexey A. Dmitriev & Anna V. Kudryavtseva. (2017) Upregulation of NETO2 gene in colorectal cancer. BMC Genetics 18:S1.
Crossref
Crossref
Varda Shoshan-Barmatz, Yakov Krelin, Anna Shteinfer-Kuzmine & Tasleem Arif. (2017) Voltage-Dependent Anion Channel 1 As an Emerging Drug Target for Novel Anti-Cancer Therapeutics. Frontiers in Oncology 7.
Crossref
Crossref
Amadou K. S. Camara, YiFan Zhou, Po-Chao Wen, Emad Tajkhorshid & Wai-Meng Kwok. (2017) Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target. Frontiers in Physiology 8.
Crossref
Crossref
Qingbin Cui, Shijun Wen & Peng Huang. (2017) Targeting cancer cell mitochondria as a therapeutic approach: recent updates. Future Medicinal Chemistry 9:9, pages 929-949.
Crossref
Crossref
F Graziano, A Ruzzo, E Giacomini, T Ricciardi, G Aprile, F Loupakis, P Lorenzini, E Ongaro, F Zoratto, V Catalano, D Sarti, E Rulli, C Cremolini, M De Nictolis, G De Maglio, A Falcone, G Fiorentini & M Magnani. (2016) Glycolysis gene expression analysis and selective metabolic advantage in the clinical progression of colorectal cancer. The Pharmacogenomics Journal 17:3, pages 258-264.
Crossref
Crossref
Wei Li, Feng Gao, Xiaoqian Ma, Ruike Wang, Xin Dong & Wei Wang. (2017) Deguelin inhibits non-small cell lung cancer via down-regulating Hexokinases II-mediated glycolysis. Oncotarget 8:20, pages 32586-32599.
Crossref
Crossref
Jiayuan Wu, Liren Hu, Fenping Wu, Lei Zou & Taiping He. (2017) Poor prognosis of hexokinase 2 overexpression in solid tumors of digestive system: a meta-analysis. Oncotarget 8:19, pages 32332-32344.
Crossref
Crossref
Anna Shteinfer-Kuzmine, Tasleem Arif, Yakov Krelin, Shambhoo Sharan Tripathi, Avijit Paul & Varda Shoshan-Barmatz. (2017) Mitochondrial VDAC1-based peptides: Attacking oncogenic properties in glioblastoma. Oncotarget 8:19, pages 31329-31346.
Crossref
Crossref
Li Xiaobo, Ma Min, Zhang Guijuan, Ma Yi, Liao Rui, Chen Ruixue, Yan Xianxin, Bie Fengjie, Huang Maojie & Liang Shijie. (2017) External use of Ruyanneixiao cream efficiently blocks precancerous mammary lesions by interfering with glycolysis induced by inhibition of hypoxia inducible factor-1α, hexokinase 2, phosphofructokinase, and pyruvate kinase M2 expression. Journal of Traditional Chinese Medicine 37:2, pages 236-243.
Crossref
Crossref
Bo-Wen Dong, Guang-Ming Qin, Yan Luo & Jian-Shan Mao. (2016) Metabolic enzymes: key modulators of functionality in cancer stem-like cells. Oncotarget 8:8, pages 14251-14267.
Crossref
Crossref
Jiang-Tao Zhong & Shui-Hong Zhou. (2016) Warburg effect, hexokinase-II, and radioresistance of laryngeal carcinoma. Oncotarget 8:8, pages 14133-14146.
Crossref
Crossref
Lei Tao, Libing Wei, Yishi Liu, Yang Ding, Xiuting Liu, Xin Zhang, Xiaoping Wang, Yuyuan Yao, Jinrong Lu, Qing Wang & Rong Hu. (2017) Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells. Biochemical Pharmacology 125, pages 12-25.
Crossref
Crossref
Huanyin Li, Lan Zheng, Yanqing Mo, Qi Gong, Aihua Jiang & Jing Zhao. (2016) Voltage-Dependent Anion Channel 1(VDAC1) Participates the Apoptosis of the Mitochondrial Dysfunction in Desminopathy. PLOS ONE 11:12, pages e0167908.
Crossref
Crossref
Ashvini K Dubey, Ashwini Godbole & M K Mathew. (2016) Regulation of VDAC trafficking modulates cell death. Cell Death Discovery 2:1.
Crossref
Crossref
Anna V. Kudryavtseva, Maria S. Fedorova, Alex Zhavoronkov, Alexey A. Moskalev, Alexander S. Zasedatelev, Alexey A. Dmitriev, Asiya F. Sadritdinova, Irina Y. Karpova, Kirill M. Nyushko, Dmitry V. Kalinin, Nadezhda N. Volchenko, Nataliya V. Melnikova, Kseniya M. Klimina, Dmitry V. Sidorov, Anatoly Y. Popov, Tatiana V. Nasedkina, Andrey D. Kaprin, Boris Y. Alekseev, George S. Krasnov & Anastasiya V. Snezhkina. (2016) Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells. BMC Genetics 17:S3.
Crossref
Crossref
Wei Li, Xiaoqian Ma, Na Li, Huasheng Liu, Qiong Dong, Juan Zhang, Cejun Yang, Yin Liu, Qi Liang, Shengwang Zhang, Chang Xu, Wei Song, Shiming Tan, Pengfei Rong & Wei Wang. (2016) Resveratrol inhibits Hexokinases II mediated glycolysis in non-small cell lung cancer via targeting Akt signaling pathway. Experimental Cell Research 349:2, pages 320-327.
Crossref
Crossref
Danya Ben-Hail, Racheli Begas-Shvartz, Moran Shalev, Anna Shteinfer-Kuzmine, Arie Gruzman, Simona Reina, Vito De Pinto & Varda Shoshan-Barmatz. (2016) Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. Journal of Biological Chemistry 291:48, pages 24986-25003.
Crossref
Crossref
Yuxin Zhou, Na Lu, Chen Qiao, Ting Ni, Zhiyu Li, Boyang Yu, Qinglong Guo & Libin Wei. (2016) FV-429 induces apoptosis and inhibits glycolysis by inhibiting Akt-mediated phosphorylation of hexokinase II in MDA-MB-231 cells. Molecular Carcinogenesis 55:9, pages 1317-1328.
Crossref
Crossref
Anna V. Kudryavtseva, Anastasia V. Lipatova, Andrew R. Zaretsky, Alexey A. Moskalev, Maria S. Fedorova, Anastasiya S. Rasskazova, Galina A. Shibukhova, Anastasiya V. Snezhkina, Andrey D. Kaprin, Boris Y. Alekseev, Alexey A. Dmitriev & George S. Krasnov. (2016) Important molecular genetic markers of colorectal cancer. Oncotarget 7:33, pages 53959-53983.
Crossref
Crossref
Cung Hoa Thien Quach, Kyung-Ho Jung, Jin Hee Lee, Jin Won Park, Seung Hwan Moon, Young Seok Cho, Yearn Seong Choe & Kyung-Han Lee. (2016) Mild Alkalization Acutely Triggers the Warburg Effect by Enhancing Hexokinase Activity via Voltage-Dependent Anion Channel Binding. PLOS ONE 11:8, pages e0159529.
Crossref
Crossref
Shihua Yao, Xiaowei Wang, Chunguang Li, Tiejun Zhao, Hai Jin & Wentao Fang. (2016) Kaempferol inhibits cell proliferation and glycolysis in esophagus squamous cell carcinoma via targeting EGFR signaling pathway. Tumor Biology 37:8, pages 10247-10256.
Crossref
Crossref
George S. Krasnov, Alexey A. Dmitriev, Nataliya V. Melnikova, Andrew R. Zaretsky, Tatiana V. Nasedkina, Alexander S. Zasedatelev, Vera N. Senchenko & Anna V. Kudryavtseva. (2016) CrossHub: a tool for multi-way analysis of The Cancer Genome Atlas (TCGA) in the context of gene expression regulation mechanisms. Nucleic Acids Research 44:7, pages e62-e62.
Crossref
Crossref
Anastasiya V. Snezhkina, George S. Krasnov, Anastasiya V. Lipatova, Asiya F. Sadritdinova, Olga L. Kardymon, Maria S. Fedorova, Nataliya V. Melnikova, Oleg A. Stepanov, Andrew R. Zaretsky, Andrey D. Kaprin, Boris Y. Alekseev, Alexey A. Dmitriev & Anna V. Kudryavtseva. (2016)
The Dysregulation of Polyamine Metabolism in Colorectal Cancer Is Associated with Overexpression of c-Myc and C/EBP
β
rather than Enterotoxigenic
Bacteroides fragilis
Infection
. Oxidative Medicine and Cellular Longevity 2016, pages 1-11.
Crossref
Crossref
Hai-nan ZhangLina YangJian-ya LingDaniel M. CzajkowskyJing-Fang WangXiao-Wei ZhangYi-Ming ZhouFeng GeMing-kun YangQian XiongShu-Juan GuoHuang-Ying LeSong-Fang WuWei YanBingya LiuHeng ZhuZhu Chen & Sheng-ce Tao. (2015) Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic. Proceedings of the National Academy of Sciences 112:49, pages 15084-15089.
Crossref
Crossref
G. S. Krasnov, A. A. Dmitriev, A. F. Sadritdinova, M. S. Fedorova, A. V. Snezhkina, N. V. Melnikova, A. V. Poteryakhina, K. M. Nyushko, M. M. Belyakov, A. D. Kaprin, A. R. Zaretsky & A. V. Kudryavtseva. (2016) Evaluation of hexokinase gene expression in colorectal cancer using bioinformatics tools. Biophysics 60:6, pages 870-875.
Crossref
Crossref
Ekaterina N. Proshkina, Mikhail V. Shaposhnikov, Asiya F. Sadritdinova, Anna V. Kudryavtseva & Alexey A. Moskalev. (2015) Basic mechanisms of longevity: A case study of Drosophila pro-longevity genes. Ageing Research Reviews 24, pages 218-231.
Crossref
Crossref
M. S. Fedorova, A. V. Kudryavtseva, V. A. Lakunina, A. V. Snezhkina, N. N. Volchenko, E. N. Slavnova, T. V. Danilova, A. F. Sadritdinova, N. V. Melnikova, A. A. Belova, K. M. Klimina, D. V. Sidorov, B. Ya. Alekseev, A. D. Kaprin, A. A. Dmitriev & G. S. Krasnov. (2015) Downregulation of OGDHL expression is associated with promoter hypermethylation in colorectal cancer. Molecular Biology 49:4, pages 608-617.
Crossref
Crossref
FENG GAO, MING LI, WEN-BIN LIU, ZHONG-SU ZHOU, RUI ZHANG, JUN-LING LI & KE-CHAO ZHOU. (2015) Epigallocatechin gallate inhibits human tongue carcinoma cells via HK2-mediated glycolysis. Oncology Reports 33:3, pages 1533-1539.
Crossref
Crossref
Peter Bai, Lilla Nagy, Tamás Fodor, Lucas Liaudet & Pal Pacher. (2015) Poly(ADP-ribose) polymerases as modulators of mitochondrial activity. Trends in Endocrinology & Metabolism 26:2, pages 75-83.
Crossref
Crossref
Cécile Martel, Zhenyu Wang & Catherine Brenner. (2014) VDAC phosphorylation, a lipid sensor influencing the cell fate. Mitochondrion 19, pages 69-77.
Crossref
Crossref
Jae-Hong Ko, Wanjun Gu, Inja Lim, Tong Zhou & Hyoweon Bang. (2014) Expression Profiling of Mitochondrial Voltage-Dependent Anion Channel-1 Associated Genes Predicts Recurrence-Free Survival in Human Carcinomas. PLoS ONE 9:10, pages e110094.
Crossref
Crossref
Neelu Yadav & Dhyan Chandra. (2014) Mitochondrial and postmitochondrial survival signaling in cancer. Mitochondrion 16, pages 18-25.
Crossref
Crossref
Friedrich P. Thinnes. (2014) Opening up of plasmalemma type-1 VDAC to form apoptotic “find me signal” pathways is essential in early apoptosis — Evidence from the pathogenesis of cystic fibrosis resulting from failure of apoptotic cell clearance followed by sterile inflammation. Molecular Genetics and Metabolism 111:4, pages 439-444.
Crossref
Crossref
Elisa García-Martínez, Leonardo S. Lino-Silva, Adriana Romo-Pérez, Alma Chavez-Blanco, Guadalupe Dominguez-Gomez, Lucia Taja-Chayeb, Horacio N. Lopez-Basave, Alejandro E. Padilla Rosciano, Consuelo Diaz-Romero, Catalina Trejo-Becerril, Aurora Gonzalez-Fierro & Alfonso Duenas-Gonzalez. (2022) Expression of Hexokinase-2 (HK2), Glutaminase-1 (GLS1) Y Fatty Acid Synthase (FASN) in Gastric Cancer and Their Prognostic Significance. SSRN Electronic Journal.
Crossref
Crossref