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Sertoli cells are the target of environmental toxicants in the testis – a mechanistic and therapeutic insight

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Chao Wang, Jiansheng Zhu, Xing Gong, Yinyin Liang, Shuyu Xu, Yongquan Yu, Liu Yang, Jiayi Xu & Shou-Lin Wang. (2021) Bioaccumulation of BDE47 in testes by TiO2 nanoparticles aggravates the reproductive impairment of male zebrafish by disrupting intercellular junctions. Nanotoxicology 15:8, pages 1073-1086.
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Yuan Li, Lishu Li, Wenjie Xiong, Xing Duan & Huaming Xi. (2024) Fluorochloridone induces mitochondrial dysfunction and apoptosis in primary goat Sertoli cells. Theriogenology 214, pages 192-200.
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Yue Feng, Junjing Wu, Runyu Lei, Yu Zhang, Mu Qiao, Jiawei Zhou, Zhong Xu, Zipeng Li, Hua Sun, Xianwen Peng & Shuqi Mei. (2023) N-Acetyl-L-Cysteine Ameliorates BPAF-Induced Porcine Sertoli Cell Apoptosis and Cell Cycle Arrest via Inhibiting the ROS Level. Toxics 11:11, pages 923.
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Tingyu Lu, Monika Mortimer, Fangfang Li, Zhi Li, Lu Chen, Minjie Li & Liang-Hong Guo. (2023) Putative adverse outcome pathways of the male reproductive toxicity derived from toxicological studies of perfluoroalkyl acids. Science of The Total Environment 873, pages 162439.
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Damilare Emmanuel Rotimi, Tobiloba Christiana Elebiyo & Oluwafemi Adeleke Ojo. (2023) Therapeutic potential of rutin in male infertility: A mini review. Journal of Integrative Medicine 21:2, pages 130-135.
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Xinyu Liu, Huaming Xi, Shuaiqi Han, Hongyun Zhang & Jianhong Hu. (2023) Zearalenone induces oxidative stress and autophagy in goat Sertoli cells. Ecotoxicology and Environmental Safety 252, pages 114571.
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Waseem Ali, Yonggang Ma, Jiaqiao Zhu, Hui Zou & Zongping Liu. (2022) Mechanisms of Cadmium-Induced Testicular Injury: A Risk to Male Fertility. Cells 11:22, pages 3601.
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Weiqi Sun, Fang Tian, Hongjie Pan, Xiuli Chang, Minjie Xia, Jingying Hu, Yuzhu Wang, Runsheng Li, Weihua Li, Mingjun Yang & Zhijun Zhou. (2022) Flurochloridone induced abnormal spermatogenesis by damaging testicular Sertoli cells in mice. Ecotoxicology and Environmental Safety 246, pages 114163.
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Yifeng Shen, Yaodong You, Kun Zhu, Chunyan Fang, Xujun Yu & Degui Chang. (2022) Bibliometric and visual analysis of blood-testis barrier research. Frontiers in Pharmacology 13.
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Elikanah Olusayo Adegoke, Md Saidur Rahman, Shereen Amjad, Won-Ki Pang, Do-Yeal Ryu, Yoo-Jin Park & Myung-Geol Pang. (2022) Bisphenol A damages testicular junctional proteins transgenerationally in mice. Environmental Pollution 302, pages 119067.
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Sheila Irais Peña-Corona, Walker Sixto Vásquez Aguire, Dinorah Vargas, Ivan Juárez & C. Adriana Mendoza-Rodríguez. (2021) Effects of bisphenols on Blood-Testis Barrier protein expression in vitro: A systematic review and meta-analysis. Reproductive Toxicology 103, pages 139-148.
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Weiqi Sun, Zhijing Ni, Rui Li, Xiuli Chang, Weihua Li, Mingjun Yang & Zhijun Zhou. (2021) Flurochloridone induces Sertoli cell apoptosis through ROS-dependent mitochondrial pathway. Ecotoxicology and Environmental Safety 216, pages 112183.
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Antonine Blondet, Guillaume Martin, Laurent Paulic, Marie-Hélène Perrard & Philippe Durand. (2021) An in vitro bioassay to assess the potential global toxicity of waters on spermatogenesis: a pilot study. Environmental Science and Pollution Research 28:21, pages 26606-26616.
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Maingredy Rodrigues Souza, Renata Mazaro-Costa & Thiago Lopes Rocha. (2021) Can nanomaterials induce reproductive toxicity in male mammals? A historical and critical review. Science of The Total Environment 769, pages 144354.
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Vaithinathan Selvaraju, Saradha Baskaran, Ashok Agarwal & Ralf Henkel. (2020) Environmental contaminants and male infertility: Effects and mechanisms. Andrologia 53:1.
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N. M. Onul, E. M. Biletska & T. A. Holovkova. (2020) Effect of Cadmium Exposure on Male Fertility. Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 5:6, pages 218-223.
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Elikanah Olusayo Adegoke, Md Saidur Rahman & Myung-Geol Pang. (2020) Bisphenols Threaten Male Reproductive Health via Testicular Cells. Frontiers in Endocrinology 11.
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