Expert Opinion on Therapeutic Targets, Volume 19, Issue 8 (2015)

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Expert Opinion on Therapeutic Targets, Volume 19, Issue 8 (2015)

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Editorial

Editorial
The potential of sestrins as therapeutic targets for diabetes
Xiaocheng Charlie Dong PhD
Pages: 1011-1015
Published online: 05 May 2015
AbstractforThe potential of sestrins as therapeutic targets for diabetes | Full Text | References | PDF (573.4 KB)
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Free Access

Original Research

Article
MiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1
Paula Mussnich, Roberta Rosa, Roberto Bianco, Alfredo Fusco & Daniela D’Angelo
Pages: 1017-1026
Published online: 24 Jun 2015
AbstractforMiR-199a-5p and miR-375 affect colon cancer cell sensitivity to cetuximab by targeting PHLPP1 | Full Text | References | PDF (690.7 KB)
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Article
MicroRNA expression in BRAF-mutated and wild-type metastatic melanoma and its correlation with response duration to BRAF inhibitors
Rosamaria Pinto, Sabino Strippoli, Simona De Summa, Anna Albano, Amalia Azzariti, Gabriella Guida, Ondina Popescu, Vito Lorusso, Michele Guida & Stefania Tommasi
Pages: 1027-1035
Published online: 09 Jul 2015
AbstractforMicroRNA expression in BRAF-mutated and wild-type metastatic melanoma and its correlation with response duration to BRAF inhibitors | Full Text | References | PDF (482.3 KB)
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Review

Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes
Lara Bellini, Mélanie Campana, Rana Mahfouz, Aurélie Carlier, Julien Véret, Christophe Magnan, Eric Hajduch & Hervé Le Stunff
Pages: 1037-1050
Published online: 26 Mar 2015
AbstractforTargeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes | Full Text | References | PDF (601.3 KB)
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Regulation of extracellular Zn2+ homeostasis in the hippocampus as a therapeutic target for Alzheimer’s disease
Atsushi Takeda & Haruna Tamano
Pages: 1051-1058
Published online: 27 Mar 2015
AbstractforRegulation of extracellular Zn2+ homeostasis in the hippocampus as a therapeutic target for Alzheimer’s disease | Full Text | References | PDF (365.2 KB)
  • 162 Views
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Blood–brain barrier endogenous transporters as therapeutic targets: a new model for small molecule CNS drug discovery
William M Pardridge
Pages: 1059-1072
Published online: 02 May 2015
AbstractforBlood–brain barrier endogenous transporters as therapeutic targets: a new model for small molecule CNS drug discovery | Full Text | References | PDF (628 KB)
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Sertoli cells are the target of environmental toxicants in the testis – a mechanistic and therapeutic insight
Ying Gao, Dolores D Mruk & C Yan Cheng
Pages: 1073-1090
Published online: 26 Apr 2015
AbstractforSertoli cells are the target of environmental toxicants in the testis – a mechanistic and therapeutic insight | Full Text | References | PDF (693 KB)
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The therapeutic potential of regulatory T cells for the treatment of autoimmune disease
Jeffrey A Bluestone (A.W. and Mary Margaret Clausen Distinguished Professor) PhD, Eleonora Trotta PhD & Daqi Xu PhD
Pages: 1091-1103
Published online: 16 Apr 2015
AbstractforThe therapeutic potential of regulatory T cells for the treatment of autoimmune disease | Full Text | References | PDF (627.7 KB)
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Adiponectin and its receptor signaling: an anti-cancer therapeutic target and its implications for anti-tumor immunity
Arnav Katira & Peng H Tan
Pages: 1105-1125
Published online: 07 May 2015
AbstractforAdiponectin and its receptor signaling: an anti-cancer therapeutic target and its implications for anti-tumor immunity | Full Text | References | PDF (827.3 KB)
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The role of probiotics on each component of the metabolic syndrome and other cardiovascular risks
Bruna Miglioranza Scavuzzi MSc, Lucia Helena da Silva Miglioranza PhD, Fernanda Carla Henrique MSc, Thanise Pitelli Paroschi MSc, Marcell Alysson Batisti Lozovoy PhD, Andréa Name Colado Simão PhD & Isaias Dichi MD PhD
Pages: 1127-1138
Published online: 15 Apr 2015
AbstractforThe role of probiotics on each component of the metabolic syndrome and other cardiovascular risks | Full Text | References | PDF (398.1 KB)
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The potential of LINGO-1 as a therapeutic target for essential tremor
José AG Agúndez MD PhD, Félix Javier Jiménez-Jimenez MD PhD, Hortensia Alonso-Navarro MD PhD & Elena García-Martín MD PhD
Pages: 1139-1148
Published online: 10 Apr 2015
AbstractforThe potential of LINGO-1 as a therapeutic target for essential tremor | Full Text | References | PDF (322.9 KB)
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Further Readings

Related articles
Page: i
Published online: 14 Jul 2015
CitationforRelated articles | Full Text | PDF (72.6 KB)
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