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Miscellaneous

Using Drosophila melanogaster to uncover human disease gene function and potential drug target proteins

Pages 387-399 | Published online: 25 Feb 2005

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Quasar Saleem Padiath, Dhanashree Paranjpe, Sanjeev Jain & Vijay Kumar Sharma. (2004) Glycogen Synthase Kinase 3β as a Likely Target for the Action of Lithium on Circadian Clocks. Chronobiology International 21:1, pages 43-55.
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Liza M. Roger, Hannah G. Reich, Evan Lawrence, Shuaifeng Li, Whitney Vizgaudis, Nathan Brenner, Lokender Kumar, Judith Klein-Seetharaman, Jinkyu Yang, Hollie M. Putnam & Nastassja A. Lewinski. (2021) Applying model approaches in non-model systems: A review and case study on coral cell culture. PLOS ONE 16:4, pages e0248953.
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Maria Rosaria Carillo, Carla Bertapelle, Filippo Scialò, Mario Siervo, Gianrico Spagnuolo, Michele Simeone, Gianfranco Peluso & Filomena Anna Digilio. (2020) L-Carnitine in Drosophila: A Review. Antioxidants 9:12, pages 1310.
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Alexander S. Chen, Joanna Wardwell-Ozgo, Nilang N. Shah, Deidre Wright, Christina L. Appin, Krishanthan Vigneswaran, Daniel J. Brat, Harley I. Kornblum & Renee D. Read. (2019) Drak/STK17A Drives Neoplastic Glial Proliferation through Modulation of MRLC Signaling. Cancer Research 79:6, pages 1085-1097.
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Tongchao Li, Hugo J. Bellen & Andrew K. Groves. (2018) Using Drosophila to study mechanisms of hereditary hearing loss . Disease Models & Mechanisms 11:6.
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Lunhao Chen, Daxiao Cheng, Jiachen Chu, Ting Zhang, Zhuoer Dong, Huifang Lou, Liya Zhu & Yijun Liu. (2018) A Novel Method to Image Macropinocytosis in Vivo. Frontiers in Neuroscience 12.
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Viet Le, Edward Anderson, Takuya Akiyama & Kristi A. Wharton. (2018) Drosophila models of FOP provide mechanistic insight. Bone 109, pages 192-200.
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Scott Alexander Keith & Arjumand Ghazi. (2014) Recent Discoveries in the Reproductive Control of Aging. Current Genetic Medicine Reports 3:1, pages 26-34.
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Jie Xu & Sara Cherry. (2014) Viruses and antiviral immunity in Drosophila. Developmental & Comparative Immunology 42:1, pages 67-84.
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Renee D. Read, Tim R. Fenton, German G. Gomez, Jill Wykosky, Scott R. Vandenberg, Ivan Babic, Akio Iwanami, Huijun Yang, Webster K. Cavenee, Paul S. Mischel, Frank B. Furnari & John B. Thomas. (2013) A Kinome-Wide RNAi Screen in Drosophila Glia Reveals That the RIO Kinases Mediate Cell Proliferation and Survival through TORC2-Akt Signaling in Glioblastoma. PLoS Genetics 9:2, pages e1003253.
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Jing Li, Tom C. Hobman & Andrew J. Simmonds. 2013. Ten Years of Progress in GW/P Body Research. Ten Years of Progress in GW/P Body Research 127 145 .
Giuseppe Vecchio, Antonio Galeone, Virgilio Brunetti, Gabriele Maiorano, Stefania Sabella, Roberto Cingolani & Pier Paolo Pompa. (2012) Concentration-Dependent, Size-Independent Toxicity of Citrate Capped AuNPs in Drosophila melanogaster. PLoS ONE 7:1, pages e29980.
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Mary. Shimoyama, Jennifer R. Smith, G. Thomas. Hayman, Victoria. Petri & Rajni. Nigam. 2012. Bioinformatics of Behavior: Part 2. Bioinformatics of Behavior: Part 2 25 46 .
Viet Q. Le & Kristi A. Wharton. (2012) Hyperactive BMP signaling induced by ALK2 R206H requires type II receptor function in a Drosophila model for classic fibrodysplasia ossificans progressiva . Developmental Dynamics 241:1, pages 200-214.
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Ayla Karatas, Fatma Ertan, Neslihan Saki, Ensar Baspınar, A. Sevim & A. Gül. (2011) Effects of a porphyrazine derivative on some developmental characteristics of Drosophila melanogaster . Acta Biologica Hungarica 62:4, pages 426-440.
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Daisuke Manita, Yuzuru Toba, Yoichi Takakusagi, Yuki Matsumoto, Tomoe Kusayanagi, Kaori Takakusagi, Senko Tsukuda, Kazunori Takada, Yoshihiro Kanai, Shinji Kamisuki, Kengo Sakaguchi & Fumio Sugawara. (2011) Camptothecin (CPT) directly binds to human heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) and inhibits the hnRNP A1/topoisomerase I interaction. Bioorganic & Medicinal Chemistry 19:24, pages 7690-7697.
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Stuart J. Grice, James N. Sleigh, Ji‐Long Liu & David B. Sattelle. (2011) Invertebrate models of spinal muscular atrophy: Insights into mechanisms and potential therapeutics. BioEssays 33:12, pages 956-965.
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Renee D. Read. (2011) Drosophila melanogaster as a model system for human brain cancers . Glia 59:9, pages 1364-1376.
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Biao Wang, Noel Moya, Sherry Niessen, Heather Hoover, Maria M. Mihaylova, Reuben J. Shaw, John R. YatesIIIIII, Wolfgang H. Fischer, John B. Thomas & Marc Montminy. (2011) A Hormone-Dependent Module Regulating Energy Balance. Cell 145:4, pages 596-606.
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Moushami Mallik & Subhash C. Lakhotia. (2010) Modifiers and mechanisms of multi-system polyglutamine neurodegenerative disorders: lessons from fly models. Journal of Genetics 89:4, pages 497-526.
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Aska Hamada, Katsuyuki Miyawaki, Eri Honda-Sumi, Kenji Tomioka, Taro Mito, Hideyo Ohuchi & Sumihare Noji. (2009) Loss-of-function analyses of the fragile X-related and dopamine receptor genes by RNA interference in the cricket Gryllus bimaculatus . Developmental Dynamics 238:8, pages 2025-2033.
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Renee D. Read, Webster K. Cavenee, Frank B. Furnari & John B. Thomas. (2009) A Drosophila Model for EGFR-Ras and PI3K-Dependent Human Glioma. PLoS Genetics 5:2, pages e1000374.
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Alfonso Martinez Arias. 2008. Drosophila. Drosophila 1 25 .
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J.C. Costello, J.E. Buchanan-Carter, M.M. Dalkilic & J. Andrews. (2007) Using Drosophila melanogaster Data to Discover Disease-Related Protein Interactions in Humans. Using Drosophila melanogaster Data to Discover Disease-Related Protein Interactions in Humans.
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Stephen Alexander, Junxia Min & Hannah Alexander. (2006) Dictyostelium discoideum to human cells: Pharmacogenetic studies demonstrate a role for sphingolipids in chemoresistance. Biochimica et Biophysica Acta (BBA) - General Subjects 1760:3, pages 301-309.
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