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The potential risk of infections during (prolonged) rituximab therapy in rheumatoid arthritis

, , & , PhD
Pages 715-726 | Published online: 15 Mar 2011

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Lara D Veeken, Merel A A Opdam, Lise M Verhoef, Calin Popa, Reinout van Crevel & Alfons A den Broeder. (2023) Infection incidence, timing and dose dependency in rheumatoid arthritis patients treated with rituximab: a retrospective cohort study. Rheumatology.
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Merel A A Opdam, J H de Leijer, Nathan den Broeder, Rogier M Thurlings, Wilfred van der Weele, Michael T Nurmohamed, Marc R Kok, Lenny van Bon, David F Ten Cate, Lise M Verhoef & Alfons A den Broeder. (2023) Rituximab dose-dependent infection risk in rheumatoid arthritis is not mediated through circulating immunoglobulins, neutrophils or B cells. Rheumatology 62:1, pages 330-334.
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Gerasimos Evangelatos, George E Fragoulis, Kalliopi Klavdianou, Melina Moschopoulou, Dimitrios Vassilopoulos & Alexios Iliopoulos. (2021) Hypogammaglobulinemia after rituximab for rheumatoid arthritis is not rare and is related with good response: 13 years real-life experience. Rheumatology 60:5, pages 2375-2382.
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Chiara Caraccio, Sachi Krishna, Darci J. Phillips & Christian M. Schürch. (2020) Bispecific Antibodies for Multiple Myeloma: A Review of Targets, Drugs, Clinical Trials, and Future Directions. Frontiers in Immunology 11.
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Yuhong Shi, Yanbin Wu, Yafei Ren, Yanan Jiang & Yiqiang Chen. (2019) Infection risks of rituximab versus non‐rituximab treatment for rheumatoid arthritis: A systematic review and meta‐analysis. International Journal of Rheumatic Diseases.
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Lucía Silva-Fernández, Diederik De Cock, Mark Lunt, Audrey S Low, Kath D Watson, Deborah P M Symmons & Kimme L Hyrich. (2018) Serious infection risk after 1 year between patients with rheumatoid arthritis treated with rituximab or with a second TNFi after initial TNFi failure: results from The British Society for Rheumatology Biologics Register for Rheumatoid Arthritis. Rheumatology 57:9, pages 1533-1540.
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Leslie R. Harrold, George W. Reed, Chitra Karki, Robert Magner, Ashwini Shewade, Ani John, Joel M. Kremer & Jeffrey D. Greenberg. (2016) Risk of Infection Associated With Subsequent Biologic Agent Use After Rituximab: Results From a National Rheumatoid Arthritis Patient Registry. Arthritis Care & Research 68:12, pages 1888-1893.
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H.-Christian von Büdingen, Arumugam Palanichamy, Klaus Lehmann-Horn, Brady A. Michel & Scott S. Zamvil. (2015) Update on the Autoimmune Pathology of Multiple Sclerosis: B-Cells as Disease-Drivers and Therapeutic Targets. European Neurology 73:3-4, pages 238-246.
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Seung Y. Chu, Karen Yeter, Roshan Kotha, Erik Pong, Yvonne Miranda, Sheryl Phung, Hsing Chen, Sung-Hyung Lee, Irene Leung, Christine Bonzon, John R. Desjarlais, William Stohl & David E. Szymkowski. (2014) Suppression of Rheumatoid Arthritis B Cells by XmAb5871, an Anti-CD19 Antibody That Coengages B Cell Antigen Receptor Complex and Fcγ Receptor IIb Inhibitory Receptor. Arthritis & Rheumatology 66:5, pages 1153-1164.
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Fabiola Atzeni, Maurizio Benucci, Salvatore Sallì, Sara Bongiovanni, Laura Boccassini & Piercarlo Sarzi-Puttini. (2013) Different effects of biological drugs in rheumatoid arthritis. Autoimmunity Reviews 12:5, pages 575-579.
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Dirk Nagorsen, Peter Kufer, Patrick A. Baeuerle & Ralf Bargou. (2012) Blinatumomab: A historical perspective. Pharmacology & Therapeutics 136:3, pages 334-342.
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