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Gliptins (dipeptidyl peptidase-4 inhibitors) and risk of acute pancreatitis

Pages 545-557 | Published online: 27 Apr 2013

Keep up to date with the latest research on this topic with citation updates for this article.

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Ping Zou, Mingxing Guo & Jingbo Hu. (2022) Evogliptin for the treatment option for type 2 diabetes: an update of the literature. Expert Review of Clinical Pharmacology 15:6, pages 747-757.
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André Jacques Scheen. (2018) The safety of gliptins : updated data in 2018. Expert Opinion on Drug Safety 17:4, pages 387-405.
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André J. Scheen. (2017) Dapagliflozin and saxagliptin tablets for adults with type 2 diabetes. Expert Review of Clinical Pharmacology 10:12, pages 1303-1316.
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André J. Scheen. (2017) Pharmacological management of type 2 diabetes: what’s new in 2017?. Expert Review of Clinical Pharmacology 10:12, pages 1383-1394.
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Qiang Du, Yan-Jun Wang, Sheng Yang & Ping Han. (2015) Clinical utility and patient considerations in the use of the sitagliptin–metformin combination in Chinese patients. Patient Preference and Adherence 9, pages 281-287.
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André J Scheen. (2015) Pharmacokinetics and clinical evaluation of the alogliptin plus pioglitazone combination for type 2 diabetes. Expert Opinion on Drug Metabolism & Toxicology 11:6, pages 1005-1020.
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André J Scheen. (2015) Safety of dipeptidyl peptidase-4 inhibitors for treating type 2 diabetes. Expert Opinion on Drug Safety 14:4, pages 505-524.
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André J Scheen. (2015) A review of gliptins for 2014. Expert Opinion on Pharmacotherapy 16:1, pages 43-62.
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Chin-Hsiao Tseng, Kuo-Yang Lee & Farn-Hsuan Tseng. (2015) An Updated Review on Cancer Risk Associated with Incretin Mimetics and Enhancers. Journal of Environmental Science and Health, Part C 33:1, pages 67-124.
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Jocelyn de Heer & Burkhard Göke. (2014) Are incretin mimetics and enhancers linked to pancreatitis and malignant transformations in pancreas?. Expert Opinion on Drug Safety 13:11, pages 1469-1481.
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Theodosios D Filippatos, Vasilios G Athyros & Moses S Elisaf. (2014) The pharmacokinetic considerations and adverse effects of DDP-4 inhibitors. Expert Opinion on Drug Metabolism & Toxicology 10:6, pages 787-812.
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Maliheh Safavi, Alireza Foroumadi & Mohammad Abdollahi. (2013) The importance of synthetic drugs for type 2 diabetes drug discovery. Expert Opinion on Drug Discovery 8:11, pages 1339-1363.
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Carolyn F Deacon & Jens J Holst. (2013) Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety. Expert Opinion on Pharmacotherapy 14:15, pages 2047-2058.
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Articles from other publishers (21)

André J. Scheen. (2021) Efficacy / safety balance of DPP-4 inhibitors versus SGLT2 inhibitors in elderly patients with type 2 diabetes. Diabetes & Metabolism 47:6, pages 101275.
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Anca Pantea Stoian, Alexandros Sachinidis, Roxana Adriana Stoica, Dragana Nikolic, Angelo Maria Patti & Ali A. Rizvi. (2020) The efficacy and safety of dipeptidyl peptidase-4 inhibitors compared to other oral glucose-lowering medications in the treatment of type 2 diabetes. Metabolism 109, pages 154295.
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Omnia Azmy Nabeh, Magdy Ishak Attallah & Nawal El‐Sayed El‐Gawhary. (2020) The pivotal relation between glucagon‐like peptides, NFκB and inflammatory bowel disease. Clinical and Experimental Pharmacology and Physiology.
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Iku Niinomi, Keiko Hosohata, Saki Oyama, Ayaka Inada, Tomohito Wakabayashi & Kazunori Iwanaga. (2019) Pharmacovigilance Assessment of Drug-Induced Acute Pancreatitis Using a Spontaneous Reporting Database. International Journal of Toxicology 38:6, pages 487-492.
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Mirza Muhammad Faran Ashraf Baig, Muhammad Naveed, Muhammad Abbas, Wen Chunxia, Sana Ullah, Muhammad Hasnat, Asam Shad, Muhammad Sohail, Ghulam Jilany Khan & Muhammad Tayyab Ansari. (2019) DNA scaffold nanoparticles coated with HPMC/EC for oral delivery. International Journal of Pharmaceutics 562, pages 321-332.
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Nurhayat Ozkan Sevencan, Aysegul Ertinmaz Ozkan & Burcak Kayhan. (2018) Linagliptin-related pancreatitis in a diabetic patient with biliary calculus. Medicine 97:50, pages e13284.
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P. Sneha & C. George Priya Doss. (2016) Gliptins in managing diabetes - Reviewing computational strategy. Life Sciences 166, pages 108-120.
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Tzu-Yuan Wang, Cheng-Hong Hsieh, Chuan-Chuan Hung, Chia-Ling Jao, Meng-Chun Chen & Kuo-Chiang Hsu. (2015) Fish skin gelatin hydrolysates as dipeptidyl peptidase IV inhibitors and glucagon-like peptide-1 stimulators improve glycaemic control in diabetic rats: A comparison between warm- and cold-water fish. Journal of Functional Foods 19, pages 330-340.
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Paul T. Fanta & Andrew M. Lowy. 2015. Yamada' s Textbook of Gastroenterology. Yamada' s Textbook of Gastroenterology 1761 1781 .
Chia-Ling Jao, Chuan-Chuan Hung, Yu-Shan Tung, Pei-Yi Lin, Meng-Chun Chen & Kuo-Chiang Hsu. (2015) The development of bioactive peptides from dietary proteins as a dipeptidyl peptidase IV inhibitor for the management of type 2 diabetes. BioMedicine 5:3.
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Gillian M. Keating. (2015) Alogliptin: A Review of Its Use in Patients with Type 2 Diabetes Mellitus. Drugs 75:7, pages 777-796.
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Saul Genuth. (2015) Should Sulfonylureas Remain an Acceptable First-Line Add-on to Metformin Therapy in Patients With Type 2 Diabetes? No, It’s Time to Move On!. Diabetes Care 38:1, pages 170-175.
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Shih-Li Huang, Chuan-Chuan Hung, Chia-Ling Jao, Yu-Shan Tung & Kuo-Chiang Hsu. (2014) Porcine skin gelatin hydrolysate as a dipeptidyl peptidase IV inhibitor improves glycemic control in streptozotocin-induced diabetic rats. Journal of Functional Foods 11, pages 235-242.
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Kate McKeage. (2014) Linagliptin: An Update of Its Use in Patients with Type 2 Diabetes Mellitus. Drugs 74:16, pages 1927-1946.
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Hsin-Chun Chou, Wen-Wen Chen & Fei-Yuan Hsiao. (2014) Acute Pancreatitis in Patients with Type 2 Diabetes Mellitus Treated with Dipeptidyl Peptidase-4 Inhibitors: A Population-Based Nested Case-Control Study. Drug Safety 37:7, pages 521-528.
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Gillian M. Keating. (2014) Vildagliptin: A Review of Its Use in Type 2 Diabetes Mellitus. Drugs 74:5, pages 587-610.
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Greg L. Plosker. (2014) Sitagliptin: A Review of Its Use in Patients with Type 2 Diabetes Mellitus. Drugs 74:2, pages 223-242.
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Harold E. Lebovitz. (2013) Incretin-Based Therapies: Facing the Realities of Benefits Versus Side Effects. Diabetes Technology & Therapeutics 15:11, pages 909-913.
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Sandeep Chakraborty, Adela Rendón-Ramírez, Bjarni Ásgeirsson, Mouparna Dutta, Anindya S. Ghosh, Masataka Oda, Ravindra Venkatramani, Basuthkar J. Rao, Abhaya M. Dandekar & Félix M. Goñi. (2015) The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins. F1000Research 2, pages 286.
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Sandeep Chakraborty, Adela Rendón-Ramírez, Bjarni Ásgeirsson, Mouparna Dutta, Anindya S. Ghosh, Masataka Oda, Ravindra Venkatramani, Basuthkar J. Rao, Abhaya M. Dandekar & Félix M. Goñi. (2015) Dipeptidyl peptidase-IV inhibitors used in type-2 diabetes inhibit a phospholipase C: a case of promiscuous scaffolds in proteins. F1000Research 2, pages 286.
Crossref
Sandeep Chakraborty, Adela Rendón-Ramírez, Bjarni Ásgeirsson, Mouparna Dutta, Anindya S. Ghosh, Masataka Oda, Ravindra Venkatramani, Basuthkar J. Rao, Abhaya M. Dandekar & Félix M. Goñi. (2013) Dipeptidyl peptidase-IV inhibitors used in type-2 diabetes inhibit a phospholipase C: a case of promiscuous scaffolds in proteins. F1000Research 2, pages 286.
Crossref

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