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Review

Safety of obesity drugs

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Pages 1083-1095 | Published online: 28 Oct 2005

Keep up to date with the latest research on this topic with citation updates for this article.

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Caroline A. Andrew, Katherine H. Saunders, Alpana P. Shukla & Louis J. Aronne. (2019) Treating obesity in patients with cardiovascular disease: the pharmacotherapeutic options. Expert Opinion on Pharmacotherapy 20:5, pages 585-593.
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Giuseppe Derosa & Pamela Maffioli. (2012) Anti-obesity drugs: a review about their effects and their safety. Expert Opinion on Drug Safety 11:3, pages 459-471.
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Louis J Aronne, Amanda G Powell & Caroline M Apovian. (2011) Emerging pharmacotherapy for obesity. Expert Opinion on Emerging Drugs 16:3, pages 587-596.
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Sonja K Billes & Frank L Greenway. (2011) Combination therapy with naltrexone and bupropion for obesity. Expert Opinion on Pharmacotherapy 12:11, pages 1813-1826.
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Harold E Bays. (2011) Lorcaserin: drug profile and illustrative model of the regulatory challenges of weight-loss drug development. Expert Review of Cardiovascular Therapy 9:3, pages 265-277.
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Patrik Roser, Franz X. Vollenweider & Wolfram Kawohl. (2010) Potential antipsychotic properties of central cannabinoid (CB1) receptor antagonists. The World Journal of Biological Psychiatry 11:2-2, pages 208-219.
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Harold E Bays. (2009) Lorcaserin and adiposopathy: 5-HT2c agonism as a treatment for ‘sick fat’ and metabolic disease. Expert Review of Cardiovascular Therapy 7:11, pages 1429-1445.
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David R Janero & Alexandros Makriyannis. (2009) Cannabinoid receptor antagonists: pharmacological opportunities, clinical experience, and translational prognosis. Expert Opinion on Emerging Drugs 14:1, pages 43-65.
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Nir Barak. (2008) Betahistine: what's new on the agenda?. Expert Opinion on Investigational Drugs 17:5, pages 795-804.
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Frank Greenway & Mary Katherine Caruso. (2007) The safety of obesity drugs – authors' response. Expert Opinion on Drug Safety 6:5, pages 477-478.
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Luc F Van Gaal, André J Scheen & Xavier Formiguera. (2007) The safety of obesity drugs – correspondence. Expert Opinion on Drug Safety 6:5, pages 475-476.
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Dagam Jeong & Ronny Priefer. (2022) Anti-obesity weight loss medications: Short-term and long-term use. Life Sciences 306, pages 120825.
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Ki-Hyo Jang & Mi-Ja Kim. (2022) A mixture of poly-γ-glutamic acid and levan ameliorates obesity in high fat diet-induced mice. Food Science and Biotechnology 31:3, pages 349-356.
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Jin Ree, Jun Il Kim, Chang Won Lee, Jisun Lee, Hyeon Jeong Kim, Seong Cheol Kim, Jae Kyung Sohng & Yong Il Park. (2021) Quinizarin suppresses the differentiation of adipocytes and lipogenesis in vitro and in vivo via downregulation of C/EBP-beta/SREBP pathway. Life Sciences 287, pages 120131.
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Ken Fujioka & Samantha R. Harris. (2020) Barriers and Solutions for Prescribing Obesity Pharmacotherapy. Endocrinology and Metabolism Clinics of North America 49:2, pages 303-314.
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Gagik R. Galstyan, Ekaterina A. Shestakova & Igor A. Sklyanik. (2017) Obesity and type 2 diabetes: can we find a compromised treatment solution?. Diabetes mellitus 20:4, pages 270-278.
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M. MacMillan, K. Cummins & K. Fujioka. (2016) What weight loss treatment options do geriatric patients with overweight and obesity want to consider?. Obesity Science & Practice 2:4, pages 477-482.
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Jinmei Li, Lili Ding, Baoliang Song, Xu Xiao, Meng Qi, Qiaoling Yang, Qiming Yang, Xiaowen Tang, Zhengtao Wang & Li Yang. (2016) Emodin improves lipid and glucose metabolism in high fat diet-induced obese mice through regulating SREBP pathway. European Journal of Pharmacology 770, pages 99-109.
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Karran A. Phillips, David H. Epstein & Kenzie L. Preston. (2014) Psychostimulant addiction treatment. Neuropharmacology 87, pages 150-160.
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C K Boughton & K G Murphy. (2013) Can neuropeptides treat obesity? A review of neuropeptides and their potential role in the treatment of obesity. British Journal of Pharmacology 170:7, pages 1333-1348.
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Shen-Chieh Chang & Winston W. Shen. (2013) Stimulants, Wakefulness-promoting Agents, and Nonstimulant Attention Deficit Hyperactivity Disorder Medications. Journal of Experimental & Clinical Medicine 5:6, pages 210-216.
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Yong Pil Hwang, Jae Ho Choi, Hyung Gyun Kim, Hyun-Sun Lee, Young Chul Chung & Hye Gwang Jeong. (2013) Saponins from Platycodon grandiflorum inhibit hepatic lipogenesis through induction of SIRT1 and activation of AMP-activated protein kinase in high-glucose-induced HepG2 cells. Food Chemistry 140:1-2, pages 115-123.
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Thing-Fong Tzeng, Hung-Jen Lu, Shorong-Shii Liou, Chia Ju Chang & I-Min Liu. (2013) Reduction of lipid accumulation in white adipose tissues by Cassia tora (Leguminosae) seed extract is associated with AMPK activation. Food Chemistry 136:2, pages 1086-1094.
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Thing-Fong Tzeng, Hung-Jen Lu, Shorong-Shii Liou, Chia Ju Chang & I-Min Liu. (2012) Emodin, a Naturally Occurring Anthraquinone Derivative, Ameliorates Dyslipidemia by Activating AMP-Activated Protein Kinase in High-Fat-Diet-Fed Rats. Evidence-Based Complementary and Alternative Medicine 2012, pages 1-9.
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Ed J. Hendricks, Frank L. Greenway, Eric C. Westman & Alok K. Gupta. (2012) Blood Pressure and Heart Rate Effects, Weight Loss and Maintenance During Long‐Term Phentermine Pharmacotherapy for Obesity. Obesity 19:12, pages 2351-2360.
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Pradeep J. Nathan, Barry V. O’Neill, Antonella Napolitano & Edward T. Bullmore. (2011) Neuropsychiatric Adverse Effects of Centrally Acting Antiobesity Drugs. CNS Neuroscience & Therapeutics 17:5, pages 490-505.
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André J. Scheen. (2011) Sibutramine on Cardiovascular Outcome. Diabetes Care 34:Supplement_2, pages S114-S119.
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A.J. Scheen. (2010) Cardiovascular Risk-Benefit Profile of Sibutramine. American Journal Cardiovascular Drugs 10:5, pages 321-334.
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Ken Fujioka & Nitasha Bakhru. (2010) Office‐based Management of Obesity. Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine 77:5, pages 466-471.
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André J. Scheen. (2010) Controversy about the Cardiovascular Safety of Sibutramine. Drug Safety 33:7, pages 615-618.
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Jamie R. Robinson & Kevin D. Niswender. (2009) What are the risks and the benefits of current and emerging weight-loss medications?. Current Diabetes Reports 9:5, pages 368-375.
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C. S. Elangbam. (2009) Review Paper: Current Strategies in the Development of Anti-obesity Drugs and Their Safety Concerns. Veterinary Pathology 46:1, pages 10-24.
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Aldo P Maggioni, Ian Caterson, Walmir Coutinho, Nick Finer, Luc Van Gaal, Arya M Sharma, Christian Torp-Pedersen, Peter Bacher, Gillian Shepherd, Rui Sun & Philip James. (2008) Tolerability of Sibutramine During a 6-week Treatment Period in High-Risk Patients With Cardiovascular Disease and/or Diabetes: A Preliminary Analysis of the Sibutramine Cardiovascular Outcomes (SCOUT) Trial. Journal of Cardiovascular Pharmacology 52:5, pages 393-402.
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Heiner K. Berthold, Susanne Unverdorben, Ralf Degenhardt, Martin Unverdorben & Ioanna Gouni‐Berthold. (2012) Effect of a Cellulose‐containing Weight‐loss Supplement on Gastric Emptying and Sensory Functions. Obesity 16:10, pages 2272-2280.
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Alma Fulurija, Thomas A. Lutz, Katja Sladko, Melania Osto, Peter Y. Wielinga, Martin F. Bachmann & Philippe Saudan. (2008) Vaccination against GIP for the Treatment of Obesity. PLoS ONE 3:9, pages e3163.
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C. A. KIRK, J. F. BOUCHER, S. J. SUNDERLAND & J. A. WREN. (2007) Influence of dirlotapide, a microsomal triglyceride transfer protein inhibitor, on the digestibility of a dry expanded diet in adult dogs. Journal of Veterinary Pharmacology and Therapeutics 30:s1, pages 66-72.
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Frank Greenway & Alok Gupta. 2007. Obesity. Obesity 199 217 .
Frank Greenway & Jolene Zheng. (2016) Electrical Stimulation as Treatment for Obesity and Diabetes. Journal of Diabetes Science and Technology 1:2, pages 251-259.
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Eve A. Roberts. (2007) Non-alcoholic Steatohepatitis in Children. Clinics in Liver Disease 11:1, pages 155-172.
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Andrew J. Krentz. (2006) Prevention of Cardiovascular Complications of the Metabolic Syndrome: Focus on Pharmacotherapy. Metabolic Syndrome and Related Disorders 4:4, pages 328-341.
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Helmy M. Siragy. (2006) Clinical trials report. Current Hypertension Reports 8:4, pages 275-276.
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