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Review

Propellant-driven metered-dose inhalers for pulmonary drug delivery

Pages 53-74 | Published online: 22 Apr 2005

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Read on this site (11)

Jake Irvine, Afrina Afrose & Nazrul Islam. (2018) Formulation and delivery strategies of ibuprofen: challenges and opportunities. Drug Development and Industrial Pharmacy 44:2, pages 173-183.
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Mariam Ibrahim, Rahul Verma & Lucila Garcia-Contreras. (2015) Inhalation drug delivery devices: technology update. Medical Devices: Evidence and Research 8, pages 131-139.
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Bing Zhu, Daniela Traini & Paul Young. (2015) Aerosol particle generation from solution-based pressurized metered dose inhalers: a technical overview of parameters that influence respiratory deposition. Pharmaceutical Development and Technology 20:8, pages 897-910.
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Nimit Mehta, Bhumika Aggarwal, Jaideep Gogtay & Sabeer Abdool-Gaffar. (2015) Comparing the efficacy and safety of salmeterol/fluticasone pMDI versus its mono-components, other LABA/ICS pMDIs and salmeterol/fluticasone Diskus in patients with asthma. Expert Opinion on Drug Delivery 12:6, pages 963-975.
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James W Ivey, Reinhard Vehring & Warren H Finlay. (2015) Understanding pressurized metered dose inhaler performance. Expert Opinion on Drug Delivery 12:6, pages 901-916.
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Leslie Y Yeo, James R Friend, Michelle P McIntosh, Els NT Meeusen & David AV Morton. (2010) Ultrasonic nebulization platforms for pulmonary drug delivery. Expert Opinion on Drug Delivery 7:6, pages 663-679.
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Daniela Traini & Paul M Young. (2009) Delivery of antibiotics to the respiratory tract: an update. Expert Opinion on Drug Delivery 6:9, pages 897-905.
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Ruben D Restrepo, Melissa T Alvarez, Leonard D Wittnebel, Helen Sorenson, Richard Wettstein, David L Vines, Jennifer Sikkema-Ortiz, Donna D Gardner & Robert L Wilkins. (2008) Medication adherence issues in patients treated for COPD. International Journal of Chronic Obstructive Pulmonary Disease 3:3, pages 371-384.
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David Lewis. (2007) Metered-dose inhalers: actuators old and new. Expert Opinion on Drug Delivery 4:3, pages 235-245.
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John Bell & Steve Newman. (2007) The rejuvenated pressurised metered dose inhaler. Expert Opinion on Drug Delivery 4:3, pages 215-234.
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Daniela Traini, Paul M. Young, Robert Price & Phillipe Rogueda. (2006) A Novel Apparatus for the Determination of Solubility in Pressurized Metered Dose Inhalers. Drug Development and Industrial Pharmacy 32:10, pages 1159-1163.
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Articles from other publishers (21)

Chandrakantsing V. Pardeshi, Sagar R. Pardeshi & Jitendra B. Naik. 2022. Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases. Advanced Drug Delivery Strategies for Targeting Chronic Inflammatory Lung Diseases 219 258 .
Melike ONGUN, Başaran MUTLU-AĞARDAN & Fusun ACARTURK. (2021) AN OVERVIEW OF SUBUNIT-BASED VACCINES FOR PULMONARY ADMINISTRATION. Ankara Universitesi Eczacilik Fakultesi Dergisi, pages 109-130.
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Tomás Sou & Christel A.S. Bergström. (2021) Contemporary Formulation Development for Inhaled Pharmaceuticals. Journal of Pharmaceutical Sciences 110:1, pages 66-86.
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Anne Haaije de Boer & Kyrre Thalberg. 2021. Inhaled Medicines. Inhaled Medicines 65 97 .
Rohitas Deshmukh, Nabamita Bandyopadhyay, Sara Nidal Abed, Shantanu Bandopadhyay, Yogendra Pal & Pran Kishore Deb. 2020. Drug Delivery Systems. Drug Delivery Systems 85 129 .
Allen E Haddrell, David Lewis, Tanya Church, Reinhard Vehring, Darragh Murnane & Jonathan P Reid. (2017) Pulmonary aerosol delivery and the importance of growth dynamics. Therapeutic Delivery 8:12, pages 1051-1061.
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Ashkan K. Yazdi & Hugh D.C. Smyth. (2016) Carrier-free high-dose dry powder inhaler formulation of ibuprofen: Physicochemical characterization and in vitro aerodynamic performance. International Journal of Pharmaceutics 511:1, pages 403-414.
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Anne Lexmond & Ben Forbes. 2017. Pharmacology and Therapeutics of Asthma and COPD. Pharmacology and Therapeutics of Asthma and COPD 265 280 .
Adam Bohr & Moritz Beck-Broichsitter. (2015) Generation of tailored aerosols for inhalative drug delivery employing recent vibrating-mesh nebulizer systems. Therapeutic Delivery 6:5, pages 621-636.
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Wouter F. Tonnis, Anke L. W. Huckriede, Wouter L. J. Hinrichs & Henderik W. Frijlink. 2015. Subunit Vaccine Delivery. Subunit Vaccine Delivery 307 329 .
Dexter J. D’Sa, David Lechuga-Ballesteros & Hak-Kim Chan. (2014) Isothermal Microcalorimetry of Pressurized Systems I: A Rapid Method to Evaluate Pressurized Metered Dose Inhaler Formulations. Pharmaceutical Research 31:10, pages 2716-2723.
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Alessandro Saadat, Bing Zhu, Mehra Haghi, Gregory King, Gaia Colombo, Paul M Young & Daniela Traini. (2014) The formulation, chemical and physical characterisation of clarithromycin-based macrolide solution pressurised metered dose inhaler. Journal of Pharmacy and Pharmacology 66:5, pages 639-645.
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Reinhard Vehring, David Lechuga-Ballesteros, Vidya Joshi, Brian Noga & Sarvajna K. Dwivedi. (2012) Cosuspensions of Microcrystals and Engineered Microparticles for Uniform and Efficient Delivery of Respiratory Therapeutics from Pressurized Metered Dose Inhalers. Langmuir 28:42, pages 15015-15023.
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Handoko Adi, Paul M Young & Daniela Traini. (2012) Co-deposition of a triple therapy drug formulation for the treatment of chronic obstructive pulmonary disease using solution-based pressurised metered dose inhalers. Journal of Pharmacy and Pharmacology 64:9, pages 1245-1253.
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Jagdeep Shur & Robert Price. (2012) Advanced microscopy techniques to assess solid-state properties of inhalation medicines. Advanced Drug Delivery Reviews 64:4, pages 369-382.
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David Lechuga-Ballesteros, Brian Noga, Reinhard Vehring, R Harris Cummings & Sarvajna K Dwivedi. (2011) Novel cosuspension metered-dose inhalers for the combination therapy of chronic obstructive pulmonary disease and asthma. Future Medicinal Chemistry 3:13, pages 1703-1718.
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Parthiban SelvamIbrahim M. El-SherbinyHugh D.C. Smyth. (2011) Swellable Hydrogel Particles for Controlled Release Pulmonary Administration Using Propellant-Driven Metered Dose Inhalers. Journal of Aerosol Medicine and Pulmonary Drug Delivery 24:1, pages 25-34.
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Sandro R. P. da Rocha, Balaji Bharatwaj & Sowmya Saiprasad. 2011. Controlled Pulmonary Drug Delivery. Controlled Pulmonary Drug Delivery 165 201 .
Libo Wu, Balaji Bharatwaj, Jayanth Panyam & Sandro R. P. da Rocha. (2007) Core–shell Particles for the Dispersion of Small Polar Drugs and Biomolecules in Hydrofluoroalkane Propellants. Pharmaceutical Research 25:2, pages 289-301.
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Daniela Traini, Paul M. Young, Philippe Rogueda & Robert Price. (2006) In Vitro Investigation of Drug Particulates Interactions and Aerosol Performance of Pressurised Metered Dose Inhalers. Pharmaceutical Research 24:1, pages 125-135.
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John Miller, Alaa Aldabet, Somaieh Soltani, Salva Golgoun, Mohammad Haroun, Marof Alkhayer & Wassim Abdelwahed. (2022) Development of an Ethanol-Free Salbutamol Sulfate Metered-Dose Inhaler: Application of Molecular Dynamic Simulation-Based Prediction of Intermolecular Interaction. SSRN Electronic Journal.
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