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Polypeptides and polyaminoacids in drug delivery

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Pages 183-201 | Published online: 13 Jan 2012

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Sandra Robla, Maria José Alonso & Noemi S. Csaba. (2020) Polyaminoacid-based nanocarriers: a review of the latest candidates for oral drug delivery. Expert Opinion on Drug Delivery 17:8, pages 1081-1092.
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M. Javiera Alvarez-Figueroa, José María Abarca-Riquelme & José Vicente González-Aramundiz. (2019) Influence of protamine shell on nanoemulsions as a carrier for cyclosporine-A skin delivery. Pharmaceutical Development and Technology 24:5, pages 630-638.
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Fernando Torres Andón & María José Alonso. (2015) Nanomedicine and cancer immunotherapy – targeting immunosuppressive cells. Journal of Drug Targeting 23:7-8, pages 656-671.
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Ziming Zhao, Yu Wang, Jin Han, Keli Wang, Dan Yang, Yihua Yang, Qian Du, Yuanjian Song & Xiaoxing Yin. (2014) Self-assembled micelles of amphiphilic poly(l-phenylalanine)-b-poly(l-serine) polypeptides for tumor-targeted delivery. International Journal of Nanomedicine 9, pages 5849-5862.
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Articles from other publishers (53)

Chien-Yu Lin, Umar-Farouk Mamani, Yuhan Guo, Yanli Liu & Kun Cheng. (2023) Peptide-Based siRNA Nanocomplexes Targeting Hepatic Stellate Cells. Biomolecules 13:3, pages 448.
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Meike N. Leiske. (2023) Poly(2-oxazoline)-derived star-shaped polymers as potential materials for biomedical applications: A review. European Polymer Journal 185, pages 111832.
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Alejandro Gallegos & Jianzhong Wu. (2022) A Molecular Theory of Polypeptide Adsorption at Inorganic Surfaces. The Journal of Physical Chemistry B 127:3, pages 794-805.
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A. V. Cherkasova, A. S. Kopylov, N. A. Aksenova, T. S. Zarkhina, I. V. Shershnev, N. N. Glagolev, P. S. Timashev & A. B. Solovieva. (2022) Effect of Pluronic F-127 on the Rate of the Release of 2-(2-Hydroxyphenyl)-4,5-Diphenyl-1H-Imidazole from Aerogel Matrices Based on Chitosan and Sodium Alginate Impregnated in an sc-Co2 Medium. Russian Journal of Physical Chemistry A 96:11, pages 2563-2570.
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Marvin Mecwan, Jinghang Li, Natashya Falcone, Menekse Ermis, Emily Torres, Ramon Morales, Alireza Hassani, Reihaneh Haghniaz, Kalpana Mandal, Saurabh Sharma, Surjendu Maity, Fatemeh Zehtabi, Behnam Zamanian, Rondinelli Herculano, Mohsen Akbari, Johnson V. John & Ali Khademhosseini. (2022) Recent advances in biopolymer-based hemostatic materials. Regenerative Biomaterials 9.
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Meike N. Leiske & Kristian Kempe. (2021) A Guideline for the Synthesis of Amino‐Acid‐Functionalized Monomers and Their Polymerizations. Macromolecular Rapid Communications 43:2, pages 2100615.
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Sai H. S. Boddu, Prakash Bhagav, Pradeep K. Karla, Shery Jacob, Mansi D. Adatiya, Tejas M. Dhameliya, Ketan M. Ranch & Amit K. Tiwari. (2021) Polyamide/Poly(Amino Acid) Polymers for Drug Delivery. Journal of Functional Biomaterials 12:4, pages 58.
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Yongyan Zhu, Ruixuan Liu, Dengyu Wu, Qianqian Yu, Kenneth J. Shea & Quanhong Zhu. (2021) Engineered polymer nanoparticles incorporating l-amino acid groups as affinity reagents for fibrinogen. Journal of Pharmaceutical Analysis 11:5, pages 596-602.
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Vahid Ahmadi, Fatemeh Zabihi, Fiorenza Rancan, Arthur Alexander Staszak, Chuanxiong Nie, Mathias Dimde, Katharina Achazi, Arno Wiehe, Annika Vogt & Rainer Haag. (2021) Amphiphilic Co-polypeptides Self-Assembled into Spherical Nanoparticles for Dermal Drug Delivery. ACS Applied Nano Materials 4:7, pages 6709-6721.
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Azade Taheri, Amirhossein Rad, Erfan Sadeghi & Jaleh Varshosaz. (2021) Comparison of Efficacy and Peripheral Neuropathy of Solvent-based Paclitaxel with Paclitaxel Poliglumex and NK105: A Systematic Review and Metaanalysis. Current Pharmaceutical Design 27:17, pages 2041-2055.
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Mahmoud Nasrollahzadeh, Mehdi Maham, Zahra Nezafat & Nasrin Shafiei. 2021. Biopolymer-Based Metal Nanoparticle Chemistry for Sustainable Applications. Biopolymer-Based Metal Nanoparticle Chemistry for Sustainable Applications 107 144 .
Kinkar Biswas, Sujit Ghosh & Basudeb Basu. (2020) Ion-exchange Resins and Polypeptide Supported Catalysts: A Critical Review. Current Green Chemistry 7:1, pages 40-52.
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Marlon Osorio, Estefanía Martinez, Tonny Naranjo & Cristina Castro. (2020) Recent Advances in Polymer Nanomaterials for Drug Delivery of Adjuvants in Colorectal Cancer Treatment: A Scientific-Technological Analysis and Review. Molecules 25:10, pages 2270.
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Nino Zavradashvili, Jordi Puiggali & Ramaz Katsarava. (2020) Artificial Polymers made of α-amino Acids - Poly(Amino Acid)s, Pseudo-Poly(Amino Acid)s, Poly(Depsipeptide)s, and Pseudo-Proteins. Current Pharmaceutical Design 26:5, pages 566-593.
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Huiping Shao, Luhui Wang, Tao Lin, Yumeng Zhang & Zhinan Zhang. (2019) Effect of protamine on Fe 3 O 4 @CS@GFTN composite magnetic nanoparticles . Functional Materials Letters 13:02, pages 2050001.
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María Victoria Lozano, Manuel J. Santander-Ortega & María José Alonso. 2020. Nanotechnology for Oral Drug Delivery. Nanotechnology for Oral Drug Delivery 419 458 .
E. Tinajero-Díaz, A. Martínez de Ilarduya, B. Cavanagh, A. Heise & S. Muñoz-Guerra. (2019) Poly(amino acid)-grafted polymacrolactones. Synthesis, self-assembling and ionic coupling properties. Reactive and Functional Polymers 143, pages 104316.
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Sonia Reimondez-Troitiño, José V. González-Aramundiz, Juan Ruiz-Bañobre, Rafael López-López, María J. Alonso, Noemi Csaba & María de la Fuente. (2019) Versatile protamine nanocapsules to restore miR-145 levels and interfere tumor growth in colorectal cancer cells. European Journal of Pharmaceutics and Biopharmaceutics 142, pages 449-459.
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Juan I. Bussio, Carla Molina-Perea & José Vicente González-Aramundiz. (2019) Hyaluronic Acid Nanocapsules as a Platform for Needle-Free Vaccination. Pharmaceutics 11:5, pages 246.
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Dazhuang Xu, Simin Zeng, Meiying Liu, Junyu Chen, Hongye Huang, Fengjie Deng, Jianwen Tian, Yuanqing Wen, Xiaoyong Zhang & Yen Wei. (2019) Preparation of PEGylated and biodegradable fluorescent organic nanoparticles with aggregation-induced emission characteristics through direct ring-opening polymerization. Journal of the Taiwan Institute of Chemical Engineers 95, pages 234-240.
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Minfeng Zhou, Ting Hou, Jinxing Li, Shanshan Yu, Zijian Xu, Miao Yin, Joseph Wang & Xiaolei Wang. (2019) Self-Propelled and Targeted Drug Delivery of Poly(aspartic acid)/Iron–Zinc Microrocket in the Stomach. ACS Nano.
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Silvia Pujals, Natalia Feiner-Gracia, Pietro Delcanale, Ilja Voets & Lorenzo Albertazzi. (2019) Super-resolution microscopy as a powerful tool to study complex synthetic materials. Nature Reviews Chemistry 3:2, pages 68-84.
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Tu-Fa Lien & Yu-Shan Lan. (2019) Effects of nanoparticle chromium mixed with γ-polyglutamic acid on the chromium bioavailability, growth performance, serum parameters and carcass traits of pigs. Animal Production Science 59:12, pages 2222.
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José Vicente González-Aramundiz, Mercedes Peleteiro, África González-Fernández, María José Alonso & Noemi Stefánia Csaba. (2018) Protamine Nanocapsules for the Development of Thermostable Adjuvanted Nanovaccines. Molecular Pharmaceutics 15:12, pages 5653-5664.
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Juan Bussio, Carla Molina-Perea & José González-Aramundiz. (2018) Lower-Sized Chitosan Nanocapsules for Transcutaneous Antigen Delivery. Nanomaterials 8:9, pages 659.
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Kevin Neumann, Annamaria Lilienkampf & Mark Bradley. (2017) Responsive polymeric nanoparticles for controlled drug delivery. Polymer International 66:12, pages 1756-1764.
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Carmen Teijeiro-Valiño, Elena Yebra-Pimentel, Jorge Guerra-Varela, Noemi Csaba, María J Alonso & Laura Sánchez. (2017) Assessment of the permeability and toxicity of polymeric nanocapsules using the zebrafish model. Nanomedicine 12:17, pages 2069-2082.
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Paulina Jakubiak, Lungile N. Thwala, Ana Cadete, Véronique Préat, Maria Jose Alonso, Ana Beloqui & Noemi Csaba. (2017) Solvent-free protamine nanocapsules as carriers for mucosal delivery of therapeutics. European Polymer Journal 93, pages 695-705.
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José Vicente González-Aramundiz, Elena Presas, Inmaculada Dalmau-Mena, Susana Martínez-Pulgarín, Covadonga Alonso, José M Escribano, María J. Alonso & Noemi Stefánia Csaba. (2017) Rational design of protamine nanocapsules as antigen delivery carriers. Journal of Controlled Release 245, pages 62-69.
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Philippe Gonzalez, Laurent Leclercq & Hervé Cottet. (2016) What is the Contribution of Counter-Ions to the Absolute Molar Mass of Polyelectrolytes Determined by SEC-MALLS?. Macromolecular Chemistry and Physics 217:23, pages 2654-2659.
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Raquel Abellan-Pose, Carmen Teijeiro-Valiño, Manuel J. Santander-Ortega, Erea Borrajo, Anxo Vidal, Marcos Garcia-Fuentes, Noémi Csaba & María José Alonso. (2016) Polyaminoacid nanocapsules for drug delivery to the lymphatic system: Effect of the particle size. International Journal of Pharmaceutics 509:1-2, pages 107-117.
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S. K. Shukla, Sudheesh K. Shukla, Penny P. Govender & N. G. Giri. (2016) Biodegradable polymeric nanostructures in therapeutic applications: opportunities and challenges. RSC Advances 6:97, pages 94325-94351.
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Taoyuan He, Di Li, Yanan Yang, Jianxun Ding, Feng Jin, Xiuli Zhuang & Xuesi Chen. (2016) Mesomeric configuration makes polyleucine micelle an optimal nanocarrier. Biomaterials Science 4:5, pages 814-818.
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José Vicente González-Aramundiz, Mercedes Peleteiro Olmedo, África González-Fernández, María José Alonso Fernández & Noemi Stefánia Csaba. (2015) Protamine-based nanoparticles as new antigen delivery systems. European Journal of Pharmaceutics and Biopharmaceutics 97, pages 51-59.
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Giovanna Lollo, Pablo Hervella, Pilar Calvo, Pablo Avilés, Maria Jose Guillén, Marcos Garcia-Fuentes, Maria José Alonso & Dolores Torres. (2015) Enhanced in vivo therapeutic efficacy of plitidepsin-loaded nanocapsules decorated with a new poly-aminoacid-PEG derivative. International Journal of Pharmaceutics 483:1-2, pages 212-219.
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Li Zhao, Chunsheng Xiao, Jianxun Ding, Xiuli Zhuang, Guangqing Gai, Liyan Wang & Xuesi Chen. (2015) Competitive binding-accelerated insulin release from a polypeptide nanogel for potential therapy of diabetes. Polymer Chemistry 6:20, pages 3807-3815.
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Morten Slyngborg & Peter Fojan. (2015) A computational study of the self-assembly of the RFFFR peptide. Physical Chemistry Chemical Physics 17:44, pages 30023-30036.
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A. Pensado, I. Fernandez-Piñeiro, B. Seijo & A. Sanchez. (2014) Anionic nanoparticles based on Span 80 as low-cost, simple and efficient non-viral gene-transfection systems. International Journal of Pharmaceutics 476:1-2, pages 23-30.
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Giovanna Lollo, Gustavo R. Rivera-Rodriguez, Jerome Bejaud, Tristan Montier, Catherine Passirani, Jean-Pierre Benoit, Marcos García-Fuentes, Maria José Alonso & Dolores Torres. (2014) Polyglutamic acid–PEG nanocapsules as long circulating carriers for the delivery of docetaxel. European Journal of Pharmaceutics and Biopharmaceutics 87:1, pages 47-54.
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Caicai Lu, Xiaojuan Wang, Guolin Wu, Jingjing Wang, Yinong Wang, Hui Gao & Jianbiao Ma. (2014) An injectable and biodegradable hydrogel based on poly(α,β-aspartic acid) derivatives for localized drug delivery. Journal of Biomedical Materials Research Part A 102:3, pages 628-638.
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Moom Sinn Aw, Mima Kurian & Dusan Losic. (2013) Polymeric Micelles for Multidrug Delivery and Combination Therapy. Chemistry – A European Journal 19:38, pages 12586-12601.
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Aiping Zhang, Zhe Zhang, Fenghua Shi, Chunsheng Xiao, Jianxun Ding, Xiuli Zhuang, Chaoliang He, Li Chen & Xuesi Chen. (2013) Redox-Sensitive Shell-Crosslinked Polypeptide -block- Polysaccharide Micelles for Efficient Intracellular Anticancer Drug Delivery . Macromolecular Bioscience 13:9, pages 1249-1258.
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Naresh Thota, Zhonglin Luo, Zhongqiao Hu & Jianwen Jiang. (2013) Self-Assembly of Amphiphilic Peptide (AF) 6 H 5 K 15 : Coarse-Grained Molecular Dynamics Simulation . The Journal of Physical Chemistry B 117:33, pages 9690-9698.
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Teresa Gonzalo, Giovanna Lollo, Marcos Garcia-Fuentes, Dolores Torres, Juan Correa, Ricardo Riguera, Eduardo Fernandez-Megia, Pilar Calvo, Pablo Avilés, Maria José Guillén & Maria José Alonso. (2013) A new potential nano-oncological therapy based on polyamino acid nanocapsules. Journal of Controlled Release 169:1-2, pages 10-16.
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M. V. Lozano, G. Lollo, M. Alonso-Nocelo, J. Brea, A. Vidal, D. Torres & M. J. Alonso. (2013) Polyarginine nanocapsules: a new platform for intracellular drug delivery. Journal of Nanoparticle Research 15:3.
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