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Leuprolide acetate: pharmaceutical use and delivery potentials

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Pages 343-354 | Published online: 16 Feb 2012

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Nardana Bazybek, Yi Wei & Guanghui Ma. (2022) Advances in encapsulating gonadotropin-releasing hormone agonists for controlled release: a review. Journal of Microencapsulation 39:5, pages 452-466.
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Maria Gabriella Matera, Luigino Calzetta, Josuel Ora, Paola Rogliani & Mario Cazzola. (2021) Pharmacokinetic/pharmacodynamic approaches to drug delivery design for inhalation drugs. Expert Opinion on Drug Delivery 18:7, pages 891-906.
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Mengting Dong, Su Jiang, Wenyan Tian, Ye Yan, Chao Gao, Jinping Gao, Yan Sheng, Yingmei Wang & Fengxia Xue. (2018) Preliminary clinical application of an aromatase inhibitor and a gonadotropin-releasing hormone agonist combination for inoperable endometrial cancer patients with comorbidities: case report and literature review. Cancer Biology & Therapy 19:11, pages 956-961.
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M. Raschid Hoda, Mario W. Kramer, Axel S. Merseburger & Marcus V. Cronauer. (2017) Androgen deprivation therapy with Leuprolide acetate for treatment of advanced prostate cancer. Expert Opinion on Pharmacotherapy 18:1, pages 105-113.
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Mehdi Rahimi, Hamid Mobedi & Aliasghar Behnamghader. (2016) In situ-forming PLGA implants loaded with leuprolide acetate/β-cyclodextrin complexes: mathematical modelling and degradation. Journal of Microencapsulation 33:4, pages 355-364.
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Mehdi Rahimi, Hamid Mobedi & Aliasghar Behnamghader. (2016) In situ forming poly(lactic acid-co-glycolic acid) implants containing leuprolide acetate/β-cyclodextrin complexes: preparation, characterization, and in vitro drug release. International Journal of Polymeric Materials and Polymeric Biomaterials 65:2, pages 75-84.
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Mehdi Rahimi, Hamid Mobedi & Aliasghar Behnamghader. (2016) Aqueous stability of leuprolide acetate: effect of temperature, dissolved oxygen, pH and complexation with β-cyclodextrin. Pharmaceutical Development and Technology 21:1, pages 108-115.
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Dustin L Cooper, Christopher M Conder & Sam Harirforoosh. (2014) Nanoparticles in drug delivery: mechanism of action, formulation and clinical application towards reduction in drug-associated nephrotoxicity. Expert Opinion on Drug Delivery 11:10, pages 1661-1680.
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Jaro Wex, Manpreet Sidhu, Isaac Odeyemi, Ahmed M Abou-Setta, Peny Retsa & Bertrand Tombal. (2013) Leuprolide acetate 1-, 3- and 6-monthly depot formulations in androgen deprivation therapy for prostate cancer in nine European countries: evidence review and economic evaluation. ClinicoEconomics and Outcomes Research 5, pages 257-269.
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Articles from other publishers (14)

Ngo Giao Thong, Vu Thi Hong Hanh, Thi Thuong Bui, Nguyen Thanh Hai, Duc Toan Nguyen, Trong Nghia Nguyen, Thi Ha Lien Nghiem, Van Hai Nguyen, Tran Linh Nguyen, Vu Dang Hoang & Tran Thi Hai Yen. (2023) Investigation on modeling and correlating drug release profiles in the accelerated and real-time conditions to formulate leuprolide acetate-loaded biodegradable microspheres. Journal of Drug Delivery Science and Technology 86, pages 104529.
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Surya K. De. 2023. Medicines for Cancer. Medicines for Cancer 161 204 .
Gi-Sang Seong, Seong-Wook Seo, Ji Young Cho, Kye Wan Lee, Beom-Jin Lee, In-Soo Yoon & Hyo-Eon Jin. (2022) Determination of Leuprolide–Fatty Acid Conjugate in Rat Plasma Using LC-MS/MS and Its Pharmacokinetics after Subcutaneous Administration in Rats. Molecules 27:24, pages 8716.
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Shihab Uddin, Md. Rafiqul Islam, Md. Raihan Chowdhury, Rie Wakabayashi, Noriho Kamiya, Muhammad Moniruzzaman & Masahiro Goto. (2021) Lipid-Based Ionic-Liquid-Mediated Nanodispersions as Biocompatible Carriers for the Enhanced Transdermal Delivery of a Peptide Drug. ACS Applied Bio Materials 4:8, pages 6256-6267.
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Mian Fu, Xiaomei Zhuang, Tianhong Zhang, Ying Guan, Qingbin Meng & Yongjun Zhang. (2020) Hydrogen‐Bonded Films for Zero‐Order Release of Leuprolide. Macromolecular Bioscience 20:9, pages 2000050.
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Mian Fu, Xiaomei Zhuang, Tianhong Zhang, Ying Guan, Qingbin Meng & Yongjun Zhang. (2020) PEGylated leuprolide with improved pharmacokinetic properties. Bioorganic & Medicinal Chemistry 28:4, pages 115306.
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Margaret Zacharin. 2020. Pediatric Pharmacotherapy. Pediatric Pharmacotherapy 507 538 .
Marjan Enayati, Hamid Mobedi, Shahriar Hojjati-Emami, Hamid Mirzadeh & Milad Jafari-Nodoushan. (2017) In situ forming PLGA implant for 90?days controlled release of leuprolide acetate for treatment of prostate cancer . Polymers for Advanced Technologies 28:7, pages 867-875.
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Mayank Singhal, Sergio del Río-Sancho, Kiran Sonaje & Yogeshvar N. Kalia. (2016) Fractional Laser Ablation for the Cutaneous Delivery of Triamcinolone Acetonide from Cryomilled Polymeric Microparticles: Creating Intraepidermal Drug Depots. Molecular Pharmaceutics 13:2, pages 500-511.
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Mandi Cafasso, Deborah A. Elder, Samantha Blum, Tammy Weis, Lindsey Hornung, Jane C. Khoury, Peggy J. Stenger & Susan R. Rose. (2015) Treatment of Central Precocious Puberty Using Gonadotropin-releasing Hormone Agonists. The Journal for Nurse Practitioners 11:7, pages 686-694.
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Jong-Lae Lim, Min-Hyo Ki, Min Kyung Joo, Sung-Won An, Kyu-Mok Hwang & Eun-Seok Park. (2015) An injectable liquid crystal system for sustained delivery of entecavir. International Journal of Pharmaceutics 490:1-2, pages 265-272.
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Kristina Malinovskaja, Timo Laaksonen & Jouni Hirvonen. (2014) Controlled transdermal delivery of leuprorelin by pulsed iontophoresis and ion-exchange fiber. European Journal of Pharmaceutics and Biopharmaceutics 88:3, pages 594-601.
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Min-Hyo Ki, Jong-Lae Lim, Jin-Young Ko, So-Hyun Park, Ji-Eon Kim, Hyun-Jong Cho, Eun-Seok Park & Dae-Duk Kim. (2014) A new injectable liquid crystal system for one month delivery of leuprolide. Journal of Controlled Release 185, pages 62-70.
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Sissel Haslund-Krog, René Mathiasen, Hanne Rolighed Christensen & Helle Holst. (2014) The impact of legislation on drug substances used off-label in paediatric wards—a nationwide study. European Journal of Clinical Pharmacology 70:4, pages 445-452.
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