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Review

Future of the transdermal drug delivery market – have we barely touched the surface?

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Pages 523-532 | Received 13 Oct 2015, Accepted 07 Dec 2015, Published online: 28 Dec 2015

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Aneta Pokorna, Pavel Bobal, Michal Oravec, Lucie Rarova, Janette Bobalova & Josef Jampilek. (2019) Investigation of Permeation of Theophylline through Skin Using Selected Piperazine-2,5-Diones. Molecules 24:3, pages 566.
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Rachel L. Creighton & Kim A. Woodrow. (2018) Microneedle‐Mediated Vaccine Delivery to the Oral Mucosa. Advanced Healthcare Materials, pages 1801180.
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Cristina Padula, Silvia Pescina, Sara Nicoli & Patrizia Santi. (2018) Generic patches containing fentanyl: In vitro equivalence and abuse deterrent evaluation according to EMA and FDA guidelines. International Journal of Pharmaceutics 537:1-2, pages 57-63.
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Kurtis Moffatt, Yujing Wang, Thakur Raghu Raj Singh & Ryan F Donnelly. (2017) Microneedles for enhanced transdermal and intraocular drug delivery. Current Opinion in Pharmacology 36, pages 14-21.
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Rong Yang, Tuo Wei, Hannah Goldberg, Weiping Wang, Kathleen Cullion & Daniel S. Kohane. (2017) Getting Drugs Across Biological Barriers. Advanced Materials 29:37, pages 1606596.
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Ryan F Donnelly. (2017) How can microneedles overcome challenges facing transdermal drug delivery?. Therapeutic Delivery 8:9, pages 725-728.
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T Salinas & M Piquette-Miller. (2017) Within Our Skin. Clinical Pharmacology & Therapeutics 102:1, pages 8-12.
Crossref
Naren Subbiah, Jesus Campagna, Patricia Spilman, Mohammad Parvez Alam, Shivani Sharma, Akishige Hokugo, Ichiro Nishimura & Varghese John. (2017) Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery. Journal of Drug Delivery 2017, pages 1-12.
Crossref
Anastasia Ripolin, James Quinn, Eneko Larrañeta, Eva Maria Vicente-Perez, Johanne Barry & Ryan F. Donnelly. (2017) Successful application of large microneedle patches by human volunteers. International Journal of Pharmaceutics 521:1-2, pages 92-101.
Crossref
Elisabete Silva, Luísa Barreiros, Marcela A. Segundo, Sofia A. Costa Lima & Salette Reis. (2017) Cellular interactions of a lipid-based nanocarrier model with human keratinocytes: Unravelling transport mechanisms. Acta Biomaterialia 53, pages 439-449.
Crossref
Ming-Ta Lee, I-Chi Lee, Shau-Wei Tsai, Chih-Hao Chen, Min-Hsien Wu & Yi-Je Juang. (2017) Spin coating of polymer solution on polydimethylsiloxane mold for fabrication of microneedle patch. Journal of the Taiwan Institute of Chemical Engineers 70, pages 42-48.
Crossref
Rakesh K. Tekade, Rahul Maheshwari & Muktika Tekade. 2017. Biopolymer-Based Composites. Biopolymer-Based Composites 81 106 .
Michael N. Pastore & Michael S. Roberts. 2017. Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds. Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds 251 262 .

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