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Expert Opinion on Drug Delivery Volume 13, 2016 - Issue 6
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Original Research

Exploratory analysis of predictors of patient adherence to subcutaneous interferon beta-1a in multiple sclerosis: TRACER study

Damiano PaolicelliDepartment of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, ItalyCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0002-8645-1763
ORCID Icon,
Eleonora CoccoMultiple Sclerosis Centre, Department of Public Health, Clinical Molecular Medicine, University of Cagliari, Cagliari, Italy
,
Valentina Di LecceDepartment of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy
,
Vita DirenzoDepartment of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, Italy
,
Lucia MoiolaDepartment of Neurology, San Raffaele Scientific Institute, University of Milan, Milan, Italy
,
Roberta LanzilloDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, Federico II University – School of Medicine, Naples, Italy
,
Paola PeriniMultiple Sclerosis Centre of the Veneto Region, Department of Neurosciences, University Hospital of Padua, Padua, Italy
,
Simona MalucchiNeurologia 2 – CRESM, A.O.U. San Luigi Gonzaga, Orbassano, Italy
,
Giovanna BorrielloMultiple Sclerosis Centre, Department of Neurology and Psychiatry, S. Andrea Hospital, Sapienza University, Rome, Italy
,
Emilio PortaccioDepartment of NEUROFARBA, University of Florence, Florence, Italy
,
Valentina PanettaL’altrastatistica srl – Consultancy & Training, Biostatistics office, Rome, Italy
,
Giuseppe FenuMultiple Sclerosis Centre, Department of Public Health, Clinical Molecular Medicine, University of Cagliari, Cagliari, Italy
,
Francesca SangalliDepartment of Neurology, San Raffaele Scientific Institute, University of Milan, Milan, Italy
,
Laura CacciaguerraMultiple Sclerosis Centre of the Veneto Region, Department of Neurosciences, University Hospital of Padua, Padua, Italy
,
Maria TrojanoDepartment of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, Bari, ItalyORCID Iconhttp://orcid.org/0000-0002-6329-8946
ORCID Icon & for the TRACER Group show all
Pages 799-805 | Received 07 Oct 2015, Accepted 22 Feb 2016, Published online: 12 Mar 2016

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Beate Bittner, Chantal Schmit Chiesi, Saifuddin Kharawala, Gavneet Kaur & Johannes Schmidt. (2019) Connected drug delivery devices to complement drug treatments: potential to facilitate disease management in home setting. Medical Devices: Evidence and Research 12, pages 101-127.
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Laura Dumitrescu, Cris S. Constantinescu & Radu Tanasescu. (2018) Recent developments in interferon-based therapies for multiple sclerosis. Expert Opinion on Biological Therapy 18:6, pages 665-680.
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Andrea Zimmer, Michael Coslovsky, Ivo Abraham & Bernhard F Décard. (2017) Adherence to fingolimod in multiple sclerosis: an investigator-initiated, prospective, observational, single-center cohort study. Patient Preference and Adherence 11, pages 1815-1830.
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Michael Munsell, Molly Frean, Joseph Menzin & Amy L Phillips. (2017) An evaluation of adherence in patients with multiple sclerosis newly initiating treatment with a self-injectable or an oral disease-modifying drug. Patient Preference and Adherence 11, pages 55-62.
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Articles from other publishers (9)

Aliza Bitton Ben-Zacharia, Bryan Walker, Amy Perrin Ross, Carlo Tornatore, Natalie C. Edwards, Yvette Lipman & Amy L. Phillips. (2023) Factors Associated With Disease-Modifying Therapy Adherence and Persistence in Multiple Sclerosis: A Scoping Literature Review. International Journal of MS Care 25:5, pages 188-195.
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Serena Barello, Damiano Paolicelli, Roberto Bergamaschi, Salvatore Cottone, Alessandra D'Amico, Viviana Annibali, Andrea Paolillo, Caterina Bosio, Valentina Panetta & Guendalina Graffigna. (2022) A nurse-led, telephone-based patient support program for improving adherence in patients with relapsing-remitting multiple sclerosis using interferon beta-1a: Lessons from a consumer-based survey on adveva® PSP. Frontiers in Psychology 13.
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Francesca Washington & Dawn Langdon. (2021) Factors affecting adherence to disease-modifying therapies in multiple sclerosis: systematic review. Journal of Neurology 269:4, pages 1861-1872.
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Aleksandra Kołtuniuk & Justyna Chojdak-Łukasiewicz. (2022) Adherence to Therapy in Patients with Multiple Sclerosis—Review. International Journal of Environmental Research and Public Health 19:4, pages 2203.
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Joshua MardanMohammad Akhtar HussainMichelle AllanLisa B Grech. (2021) Objective medication adherence and persistence in people with multiple sclerosis: a systematic review, meta-analysis, and meta-regression. Journal of Managed Care & Specialty Pharmacy 27:9, pages 1273-1295.
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Francesco Saccà, Roberta Lanzillo, Alessio Signori, Giorgia T Maniscalco, Elisabetta Signoriello, Salvatore Lo Fermo, Annamaria Repice, Pietro Annovazzi, Damiano Baroncini, Marinella Clerico, Eleonora Binello, Raffaella Cerqua, Giorgia Mataluni, Simona Bonavita, Luigi Lavorgna, Ignazio Roberto Zarbo, Alice Laroni, Silvia Rossi, Lorena Pareja Gutierrez, Sara La Gioia, Barbara Frigeni, Valeria Barcella, Jessica Frau, Eleonora Cocco, Giuseppe Fenu, Valentina Torri Clerici, Arianna Sartori, Sarah Rasia, Cinzia Cordioli, Alessia Di Sapio, Simona Pontecorvo, Roberta Grasso, Caterina Barrilà, Cinzia Valeria Russo, Sabrina Esposito, Domenico Ippolito, Francesca Bovis, Fabio Gallo & Maria Pia Sormani. (2018) Determinants of therapy switch in multiple sclerosis treatment-naïve patients: A real-life study. Multiple Sclerosis Journal 25:9, pages 1263-1272.
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Chiara Zecca, Giulio Disanto, Sarah Mühl & Claudio Gobbi. (2017) Subjective patient-reported versus objective adherence to subcutaneous interferon β-1a in multiple sclerosis using RebiSmart®: the CORE study. BMC Neurology 17:1.
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A. Ghezzi, A. Bianchi, D. Baroncini, A. Bertolotto, S. Malucchi, V. Bresciamorra, R. Lanzillo, N. Milani, V. Martinelli, F. Patti, C. Chisari, M. Rottoli, M. Simone, D. Paolicelli & A. Visconti. (2017) A multicenter, observational, prospective study of self- and parent-reported quality of life in adolescent multiple sclerosis patients self-administering interferon-β1a using RebiSmart™—the FUTURE study. Neurological Sciences 38:11, pages 1999-2005.
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Peter Joseph Jongen, Wim A. Lemmens, Erwin L. Hoogervorst & Rogier Donders. (2017) Glatiramer acetate treatment persistence - but not adherence - in multiple sclerosis patients is predicted by health-related quality of life and self-efficacy: a prospective web-based patient-centred study (CAIR study). Health and Quality of Life Outcomes 15:1.
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