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Review

Developments in polymeric devices for oral insulin delivery

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Pages 403-415 | Published online: 21 Apr 2008

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Read on this site (11)

Emanuele Mauri, Simonetta Papa, Maurizio Masi, Pietro Veglianese & Filippo Rossi. (2017) Novel functionalization strategies to improve drug delivery from polymers. Expert Opinion on Drug Delivery 14:11, pages 1305-1313.
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Maryam Atabay, Jaber Jahanbin Sardroodi & Alireza Rastkar Ebrahimzadeh. (2017) Adsorption and immobilisation of human insulin on graphene monoxide, silicon carbide and boron nitride nanosheets investigated by molecular dynamics simulation. Molecular Simulation 43:4, pages 298-311.
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Arijit Guha, Nikhil Biswas, Kaustav Bhattacharjee, Nityananda Sahoo & Ketousetuo Kuotsu. (2016) pH responsive cylindrical MSN for oral delivery of insulin-design, fabrication and evaluation. Drug Delivery 23:9, pages 3552-3561.
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Yongli Shi, Xiao Wang, Xiuzhen Deng, Ruiqiong Tian, Yuehong Zhang, Qing Shang & Nan Chen. (2016) Release profile of insulin from pH-sensitive hydrogel and its hypoglycemic effect by oral administration. Journal of Biomaterials Science, Polymer Edition 27:1, pages 86-96.
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F. Cárdenas-Bailón, G. Osorio-Revilla & T. Gallardo-Velázquez. (2015) Microencapsulation of insulin using a W/O/W double emulsion followed by complex coacervation to provide protection in the gastrointestinal tract. Journal of Microencapsulation 32:3, pages 308-316.
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Aiala Salvador, Manoli Igartua, Rosa María Hernández & José Luis Pedraz. (2014) Designing improved poly lactic-co-glycolic acid microspheres for a malarial vaccine: incorporation of alginate and polyinosinic–polycytidilic acid. Journal of Microencapsulation 31:6, pages 560-566.
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Tejraj M Aminabhavi, Mallikarjuna N Nadagouda, Shrinivas D Joshi & Uttam A More. (2014) Guar gum as platform for the oral controlled release of therapeutics. Expert Opinion on Drug Delivery 11:5, pages 753-766.
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Dewi Melani Hariyadi, Yiwei Wang, Sharon Chien-Yu Lin, Thor Bostrom, Bhesh Bhandari & Allan G. A. Coombes. (2012) Novel alginate gel microspheres produced by impinging aerosols for oral delivery of proteins. Journal of Microencapsulation 29:3, pages 250-261.
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Raghavendra C. Mundargi, Vidhya Rangaswamy & Tejraj M. Aminabhavi. (2011) pH-Sensitive oral insulin delivery systems using Eudragit microspheres. Drug Development and Industrial Pharmacy 37:8, pages 977-985.
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Raghavendra C. Mundargi, Vidhya Rangaswamy & Tejraj M. Aminabhavi. (2011) Poly(N-vinylcaprolactam-co-methacrylic acid) hydrogel microparticles for oral insulin delivery. Journal of Microencapsulation 28:5, pages 384-394.
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Rekha M Ramesan & Chandra P Sharma. (2009) Challenges and advances in nanoparticle-based oral insulin delivery. Expert Review of Medical Devices 6:6, pages 665-676.
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Articles from other publishers (45)

Yiqun Liu, Li Yang & Yue Cui. (2023) Review of point-of-care platforms for diabetes: (2) medications and devices. Sensors and Actuators Reports 5, pages 100150.
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G. Manasa, Ronald J. Mascarenhas, Nagaraj P. Shetti, Shweta J. Malode, Amit Mishra, Soumen Basu & Tejraj M. Aminabhavi. (2022) Skin Patchable Sensor Surveillance for Continuous Glucose Monitoring. ACS Applied Bio Materials 5:3, pages 945-970.
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Jaya R. Lakkakula, Rui Werner Maçedo Krause, Deepika Divakaran, Sagar Barage & Rohit Srivastava. (2021) 5-Fu inclusion complex capped gold nanoparticles for breast cancer therapy. Journal of Molecular Liquids 341, pages 117262.
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Bo Sun, Weijun Wang, Zhibin He, Min Zhang, Fangong Kong & Mohini Sain. (2020) Biopolymer Substrates in Buccal Drug Delivery: Current Status and Future Trend. Current Medicinal Chemistry 27:10, pages 1661-1669.
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Rumaisa Rashid, Amreen Naqash, Ghulam Nabi Bader & Faheem A. Sheikh. 2020. Application of Nanotechnology in Biomedical Sciences. Application of Nanotechnology in Biomedical Sciences 99 117 .
Sevil Cikrikci, Behic Mert & Mecit Halil Oztop. (2018) Development of pH Sensitive Alginate/Gum Tragacanth Based Hydrogels for Oral Insulin Delivery. Journal of Agricultural and Food Chemistry 66:44, pages 11784-11796.
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Xiaoliang Qi, Yue Yuan, Jianfa Zhang, Jeff W. M. Bulte & Wei Dong. (2018) Oral Administration of Salecan-Based Hydrogels for Controlled Insulin Delivery. Journal of Agricultural and Food Chemistry 66:40, pages 10479-10489.
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Li Zhang, Yu-Xiao Zhang, Jia-Ni Qiu, Jian Li, Wuya Chen & Yan-Qing Guan. (2017) Preparation and Characterization of Hypoglycemic Nanoparticles for Oral Insulin Delivery. Biomacromolecules 18:12, pages 4281-4291.
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Gauravkumar R. Agrawal, Pravin Wakte & Santosh Shelke. (2017) Formulation, physicochemical characterization and in vitro evaluation of human insulin-loaded microspheres as potential oral carrier. Progress in Biomaterials 6:3, pages 125-136.
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T.M. Aminabhavi & S.P. Dharupaneedi. 2017. Chitosan Based Biomaterials Volume 1. Chitosan Based Biomaterials Volume 1 295 319 .
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Vali Ahmadi, Jalil Karnoosh-Yamchi, Akbar Aliasgharzadeh, Alireza Ostad-Rahimi, Zeinab Nikniaz, Roya Salehi & Majid Mobasseri. (2016) The Effect of Nanohydrogel Oral Insulin Therapy on Serum Glucose and Insulin Level in Patients with Type 2 Diabetes: A Pilot Study. Pharmaceutical Sciences 22:3, pages 181-185.
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J. R. Anusha & Albin T. Fleming. (2016) Synthesis and Characterization of Chitosan Nanoaggregates from Gladius of Uroteuthis duvauceli . International Journal of Biomaterials 2016, pages 1-9.
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Tejraj M. Aminabhavi & Anand S. Deshmukh. 2016. Polymeric Hydrogels as Smart Biomaterials. Polymeric Hydrogels as Smart Biomaterials 45 71 .
Kazutoshi Haraguchi, Jinyan Ning & Guang Li. (2015) Swelling/deswelling behavior of zwitterionic nanocomposite gels consisting of sulfobetaine polymer–clay networks. European Polymer Journal 68, pages 630-640.
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Kiran Chaturvedi, Kuntal Ganguly, Anandrao R Kulkarni, Walter E Rudzinski, Leslie Krauss, Mallikarjuna N Nadagouda & Tejraj M Aminabhavi. (2015) Oral insulin delivery using deoxycholic acid conjugated PEGylated polyhydroxybutyrate co-polymeric nanoparticles. Nanomedicine 10:10, pages 1569-1583.
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Minakshi Kanzarkar, Prem Prakash Pathak, Mandar Vaidya, Charles Brumlik & Abhishek Choudhury. (2015) Oral insulin-delivery system for diabetes mellitus. Pharmaceutical Patent Analyst 4:1, pages 29-36.
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Kuntal Ganguly, Kiran Chaturvedi, Uttam A. More, Mallikarjuna N. Nadagouda & Tejraj M. Aminabhavi. (2014) Polysaccharide-based micro/nanohydrogels for delivering macromolecular therapeutics. Journal of Controlled Release 193, pages 162-173.
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Shalin P. Thakker, Ajit P. Rokhade, Shivayya S. Abbigerimath, Sudhir R. Iliger, Venkatarao H. Kulkarni, Uttam A. More & Tejraj M. Aminabhavi. (2014) Inter-polymer complex microspheres of chitosan and cellulose acetate phthalate for oral delivery of 5-fluorouracil. Polymer Bulletin 71:8, pages 2113-2131.
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Hui-Peng Lim, Beng-Ti Tey & Eng-Seng Chan. (2014) Particle designs for the stabilization and controlled-delivery of protein drugs by biopolymers: A case study on insulin. Journal of Controlled Release 186, pages 11-21.
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S. Olya, M. Khorvash, H.R. Rahmani, S. Esmaeilkhanian, B. Olya & H. Sadri. (2014) Oral delivery of insulin-loaded nanoparticles in diabetic rabbits and in sheep. Czech Journal of Animal Science 59:6, pages 251-256.
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Arun Verma, Nitin Kumar, Rishabha Malviya & Pramod Kumar Sharma. (2014) Emerging Trends in Noninvasive Insulin Delivery. Journal of Pharmaceutics 2014, pages 1-9.
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Sunandini Chopra, Jong-Min Lim, Rohit Karnik & Omid Farokhzad. (2014) Role of electrostatic interactions in protein loading in PLGA-PEG nanoparticles. Role of electrostatic interactions in protein loading in PLGA-PEG nanoparticles.
Shilan Chen, Mingzhu Liu, Shuping Jin & Yong Chen. (2013) pH-/temperature-sensitive carboxymethyl chitosan/poly(N-isopropylacrylamide-co-methacrylic acid) IPN: preparation, characterization and sustained release of riboflavin. Polymer Bulletin 71:3, pages 719-734.
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Meiyu Peng, Shuxin Xu, Yong Zhang, Lijuan Zhang, Bingqing Huang, Shuyu Fu, Zhenyi Xue, Yurong Da, Yun Dai, Liang Qiao, Anjie Dong, Rongxin Zhang & Wenbo Meng. (2014) Thermosensitive Injectable Hydrogel Enhances the Antitumor Effect of Embelin in Mouse Hepatocellular Carcinoma. Journal of Pharmaceutical Sciences 103:3, pages 965-973.
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Thundiparambil Azeez Sonia & Chandra P. Sharma. 2014. Oral Delivery of Insulin. Oral Delivery of Insulin 219 256 .
Sae Rom Choi, Dong-Jin Jang, Sanghyun Kim, Sunhyung An, Jinwoo Lee, Euichaul Oh & Jungbae Kim. (2014) Polymer-coated spherical mesoporous silica for pH-controlled delivery of insulin. J. Mater. Chem. B 2:6, pages 616-619.
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Ming-Hung Ling & Mei-Chin Chen. (2013) Dissolving polymer microneedle patches for rapid and efficient transdermal delivery of insulin to diabetic rats. Acta Biomaterialia 9:11, pages 8952-8961.
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Pan He, Huaiyu Liu, Zhaohui Tang, Mingxiao Deng, Yan Yang, Xuan Pang & Xuesi Chen. (2013) Poly(ester amide) blend microspheres for oral insulin delivery. International Journal of Pharmaceutics 455:1-2, pages 259-266.
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Nadezhda G. Balabushevich, Mikhail A. Pechenkin, Elena D. Shibanova, Dmitry V. Volodkin & Elena V. Mikhalchik. (2013) Multifunctional Polyelectrolyte Microparticles for Oral Insulin Delivery. Macromolecular Bioscience 13:10, pages 1379-1388.
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Kiran Chaturvedi, Kuntal Ganguly, Mallikarjuna N. Nadagouda & Tejraj M. Aminabhavi. (2013) Polymeric hydrogels for oral insulin delivery. Journal of Controlled Release 165:2, pages 129-138.
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Antonio J. Ribeiro, Raquel Seiça & Francisco Veiga. 2013. Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment. Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment 109 125 .
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Concetta Giovino, Isaac Ayensu, John Tetteh & Joshua S. Boateng. (2012) Development and characterisation of chitosan films impregnated with insulin loaded PEG-b-PLA nanoparticles (NPs): A potential approach for buccal delivery of macromolecules. International Journal of Pharmaceutics 428:1-2, pages 143-151.
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Alessandra Maroni, Lucia Zema, Maria Dorly Del Curto, Anastasia Foppoli & Andrea Gazzaniga. (2012) Oral colon delivery of insulin with the aid of functional adjuvants. Advanced Drug Delivery Reviews 64:6, pages 540-556.
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Aura-Ileana Moreno-Vega, Teresa Gómez-Quintero, Rosa-Elvira Nuñez-Anita, Laura-Susana Acosta-Torres & Víctor Castaño. (2012) Polymeric and Ceramic Nanoparticles in Biomedical Applications. Journal of Nanotechnology 2012, pages 1-10.
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Jeffrey W. Card & Bernadene A. Magnuson. (2011) A review of the efficacy and safety of nanoparticle-based oral insulin delivery systems. American Journal of Physiology-Gastrointestinal and Liver Physiology 301:6, pages G956-G967.
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Josias H. Hamman & Jan H. Steenekamp. 2011. Peptide Drug Discovery and Development. Peptide Drug Discovery and Development 71 90 .
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Ralf Smeets, Frank Gerhards, Jamal Stein, Rui Miguel Pereira Paz, Stephan Vogt, Christoph Pautke, Jochen Weitz & Andreas Kolk. (2011) A novel hemostatic delivery device for thrombin: Biodegradable poly(D,L-lactide-co-glycolide) 50:50 microspheres. Journal of Biomedical Materials Research Part A 96A:1, pages 177-185.
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Baljit Singh & Nirmala Chauhan. (2010) Dietary fiber psyllium based hydrogels for use in insulin delivery. International Journal of Diabetes Mellitus 2:1, pages 32-37.
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Christiane Damg?Marie Socha, Nathalie Ubrich & Philippe Maincent. (2010) Poly(?-caprolactone)/eudragit nanoparticles for oral delivery of aspart-insulin in the treatment of diabetes. Journal of Pharmaceutical Sciences 99:2, pages 879-889.
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