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Expert Opinion on Drug Delivery Volume 5, 2008 - Issue 7
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Review

Drug-eluting polymer implants in cancer therapy

Agata A Exner Case Western Reserve University, Department of Radiology, 11100 Euclid Avenue, Cleveland, OH 44106-5056, USA +1 216 844 3544; +1 216 844 5922; [email protected]; Case Western Reserve University, Biomedical Engineering, 11100 Euclid Avenue, Cleveland, OH 44106-7207, USA
, PhD &
Gerald M Saidel Case Western Reserve University, Biomedical Engineering, 11100 Euclid Avenue, Cleveland, OH 44106-7207, USA
Pages 775-788 | Published online: 01 Jul 2008

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Raquel De Souza, Payam Zahedi, Christine J. Allen & Micheline Piquette-Miller. (2010) Polymeric drug delivery systems for localized cancer chemotherapy. Drug Delivery 17:6, pages 365-375.
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Jialu Gao, Yong Xu, Yan Zheng, Xin Wang, Shuting Li, Guoqing Yan, Jun Wang & Rupei Tang. (2019) pH-sensitive carboxymethyl chitosan hydrogels via acid-labile ortho ester linkage as an implantable drug delivery system. Carbohydrate Polymers 225, pages 115237.
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Noam Y. Steinman & Abraham J. Domb. (2019) Injectable Pasty Biodegradable Polyesters Derived from Castor Oil and Hydroxyl-Acid Lactones. Journal of Pharmacology and Experimental Therapeutics 370:3, pages 736-741.
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Kelsey A. Hopkins, Nicole Vike, Xin Li, Jacqueline Kennedy, Emma Simmons, Joseph Rispoli & Luis Solorio. (2019) Noninvasive characterization of in situ forming implant diffusivity using diffusion-weighted MRI. Journal of Controlled Release 309, pages 289-301.
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Peeyush Kumar Sharma, Sagarika Taneja & Yashveer Singh. (2018) Hydrazone-Linkage-Based Self-Healing and Injectable Xanthan–Poly(ethylene glycol) Hydrogels for Controlled Drug Release and 3D Cell Culture. ACS Applied Materials & Interfaces 10:37, pages 30936-30945.
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Sepehr Talebian, Javad Foroughi, Samantha J. Wade, Kara L. Vine, Alireza Dolatshahi‐Pirouz, Mehdi Mehrali, João Conde & Gordon G. Wallace. (2018) Biopolymers for Antitumor Implantable Drug Delivery Systems: Recent Advances and Future Outlook. Advanced Materials 30:31.
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Anoop Kumar & Jonathan Pillai. 2018. Nanostructures for the Engineering of Cells, Tissues and Organs. Nanostructures for the Engineering of Cells, Tissues and Organs 473 511 .
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Elena González-Domínguez, Benito Rodríguez-González, Moisés Pérez-Lorenzo & Miguel A. Correa-Duarte. (2017) “Takeaway” drug delivery: A new nanomedical paradigm. Nano Research 10:7, pages 2234-2243.
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Luis Solorio, Hanping Wu, Christopher Hernandez, Mihika Gangolli & Agata A Exner. (2016) Ultrasound-guided intratumoral delivery of doxorubicin from in situ forming implants in a hepatocellular carcinoma model . Therapeutic Delivery 7:4, pages 201-212.
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Diana P. Ferreira, David S. Conceição, F. Fernandes, T. Sousa, Ricardo C. Calhelha, Isabel C. F. R. Ferreira, Paulo F. Santos & L. F. Vieira Ferreira. (2016) Characterization of a Squaraine/Chitosan System for Photodynamic Therapy of Cancer. The Journal of Physical Chemistry B 120:7, pages 1212-1220.
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Lilong Gao, Yadong Chen, Qiaojie Luo, Ying Wang, Xiaodong Li, Zhiquan Shen & Weipu Zhu. (2016) Injectable camptothecin conjugated hydrogels with simultaneous drug release and degradation. RSC Advances 6:97, pages 94661-94668.
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Ana C. Fonseca, Arménio C. Serra & Jorge F. J. Coelho. (2015) Bioabsorbable polymers in cancer therapy: latest developments. EPMA Journal 6:1.
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Luis Solorio & Agata A. Exner. (2015) Effect of the Subcutaneous Environment on Phase-Sensitive In Situ-Forming Implant Drug Release, Degradation, and Microstructure. Journal of Pharmaceutical Sciences 104:12, pages 4322-4328.
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Luis solorio, Divya Sundarapandiyan, Alex Olear & Agata A. Exner. (2015) The Effect of Additives on the Behavior of Phase Sensitive In Situ Forming Implants. Journal of Pharmaceutical Sciences 104:10, pages 3471-3480.
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Shuxin Xu, Weiwei Wang, Xijing Li, Jianping Liu, Anjie Dong & Liandong Deng. (2014) Sustained release of PTX-incorporated nanoparticles synergized by burst release of DOX?HCl from thermosensitive modified PEG/PCL hydrogel to improve anti-tumor efficiency. European Journal of Pharmaceutical Sciences 62, pages 267-273.
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Yan Zhang, Shi Liu, Xue Wang, Zhi-yun Zhang, Xia-bin Jing, Ping Zhang & Zhi-gang Xie. (2014) Prevention of local liver cancer recurrence after surgery using multilayered cisplatin-loaded polylactide electrospun nanofibers. Chinese Journal of Polymer Science 32:8, pages 1111-1118.
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Stefan T. Yohe, Jonathan D. Freedman, Eric J. Falde, Yolonda L. Colson & Mark W. Grinstaff. (2013) A Mechanistic Study of Wetting Superhydrophobic Porous 3D Meshes. Advanced Functional Materials 23:29, pages 3628-3637.
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Stefan T. Yohe, Victoria L.M. Herrera, Yolonda L. Colson & Mark W. Grinstaff. (2012) 3D superhydrophobic electrospun meshes as reinforcement materials for sustained local drug delivery against colorectal cancer cells. Journal of Controlled Release 162:1, pages 92-101.
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Luis Solorio, Alexander M. Olear, Haoyan Zhou, Ashlei C. Beiswenger & Agata A. Exner. (2012) Effect of cargo properties on in situ forming implant behavior determined by noninvasive ultrasound imaging. Drug Delivery and Translational Research 2:1, pages 45-55.
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M. Mohamed, G. Borchard & O. Jordan. (2012) In situ forming implants for local chemotherapy and hyperthermia of bone tumors. Journal of Drug Delivery Science and Technology 22:5, pages 393-408.
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Luis Solorio, Ravi B Patel, Hanping Wu, Tianyi Krupka & Agata A Exner. (2010) Advances in image-guided intratumoral drug delivery techniques. Therapeutic Delivery 1:2, pages 307-322.
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Luis Solorio, Brett M. Babin, Ravi B. Patel, Justyna Mach, Nami Azar & Agata A. Exner. (2010) Noninvasive characterization of in situ forming implants using diagnostic ultrasound. Journal of Controlled Release 143:2, pages 183-190.
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Ravi B. Patel, Angela N. Carlson, Luis Solorio & Agata A. Exner. (2010) Characterization of formulation parameters affecting low molecular weight drug release from in situ forming drug delivery systems . Journal of Biomedical Materials Research Part A 9999A, pages NA-NA.
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