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The effect of grapefruit juice on drug disposition

, PharmD, , PhD, , PhD & , MD
Pages 267-286 | Published online: 22 Jan 2011

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Crossref
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Crossref
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Stéphane Mouly, Célia Lloret-Linares, Pierre-Olivier Sellier, Damien Sene & J.-F. Bergmann. (2017) Is the clinical relevance of drug-food and drug-herb interactions limited to grapefruit juice and Saint-John’s Wort?. Pharmacological Research 118, pages 82-92.
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Viktoriia Burkina, Martin Krøyer Rasmussen, Nadezhda Pilipenko & Galia Zamaratskaia. (2017) Comparison of xenobiotic-metabolising human, porcine, rodent, and piscine cytochrome P450. Toxicology 375, pages 10-27.
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Nidal A. Qinna, Obbei A. Ismail, Tawfiq M. Alhussainy, Nasir M. Idkaidek & Tawfiq A. Arafat. (2014) Evidence of reduced oral bioavailability of paracetamol in rats following multiple ingestion of grapefruit juice. European Journal of Drug Metabolism and Pharmacokinetics 41:2, pages 187-195.
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S. Mouly, M. Morgand, A. Lopes, C. Lloret-Linares & J.-F. Bergmann. (2015) Interactions médicaments–aliments en médecine interne : quels messages pour le clinicien ?. La Revue de Médecine Interne 36:8, pages 530-539.
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Tanis R. Fenton, Beth Armour & Jayne Thirsk. (2015) Comment on ?Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application?. Journal of Nutrition and Metabolism 2015, pages 1-2.
Crossref
Chandra Prakash, Baltazar Zuniga, Chung Seog Song, Shoulei Jiang, Jodie Cropper, Sulgi Park & Bandana Chatterjee. (2015) Nuclear Receptors in Drug Metabolism, Drug Response and Drug Interactions. Nuclear Receptor Research 2.
Crossref
Brett Fleisher, Jesse Unum, Jie Shao & Guohua An. (2015) Ingredients in Fruit Juices Interact with Dasatinib Through Inhibition of BCRP: A New Mechanism of Beverage-Drug Interaction. Journal of Pharmaceutical Sciences 104:1, pages 266-275.
Crossref
Patricia Campos-Bedolla, Fruzsina R. Walter, Szilvia Veszelka & Mária A. Deli. (2014) Role of the Blood–Brain Barrier in the Nutrition of the Central Nervous System. Archives of Medical Research 45:8, pages 610-638.
Crossref
Rostislav Chudnovskiy, Airlia Thompson, Kevin Tharp, Marc Hellerstein, Joseph L. Napoli & Andreas Stahl. (2014) Consumption of Clarified Grapefruit Juice Ameliorates High-Fat Diet Induced Insulin Resistance and Weight Gain in Mice. PLoS ONE 9:10, pages e108408.
Crossref
Chunxian ChenQibin YuXu WeiPaul F. CancalonFred G. Gmitter, Jr.. (2014) Identification of genes associated with low furanocoumarin content in grapefruit. Genome 57:10, pages 537-545.
Crossref
Karen M. VanderMolen, Garrett R. Ainslie, Mary F. Paine & Nicholas H. Oberlies. (2014) Labeled content of two furanocoumarins in dietary supplements correlates with neither actual content nor CYP3A inhibitory activity. Journal of Pharmaceutical and Biomedical Analysis 98, pages 260-265.
Crossref
L Zhang, F Wu, S C Lee, H Zhao & L Zhang. (2014) pH-Dependent Drug?Drug Interactions for Weak Base Drugs: Potential Implications for New Drug Development. Clinical Pharmacology & Therapeutics 96:2, pages 266-277.
Crossref
Huifen Wang, Jeffrey B. Blumberg, C.-Y. Oliver Chen, Sang-Woon Choi, Michael P. Corcoran, Susan S. Harris, Paul F. Jacques, Aleksandra S. Kristo, Chao-Qiang Lai, Stefania Lamon-Fava, Nirupa R. Matthan, Diane L. McKay, Mohsen Meydani, Laurence D. Parnell, Max P. Prokopy, Tammy M. Scott & Alice H. Lichtenstein. (2014) Dietary modulators of statin efficacy in cardiovascular disease and cognition. Molecular Aspects of Medicine 38, pages 1-53.
Crossref
S. Gautier, J. Béné, M. Auffret & J. Caron. (2014) Interactions entre pamplemousse et médicamentsInteractions between grapefruit and drugs. Phytothérapie 12:2, pages 98-104.
Crossref
Matthias Strupler & Claudio Perret. 2014. Sports Nutrition for Paralympic Athletes. Sports Nutrition for Paralympic Athletes 153 166 .
Nuggehally R. Srinivas. (2013) Is pomegranate juice a potential perpetrator of clinical drug–drug interactions? Review of the in vitro, preclinical and clinical evidence. European Journal of Drug Metabolism and Pharmacokinetics 38:4, pages 223-229.
Crossref
Christian A. Heinen, Stefan Reuss, Gordon L. Amidon & Peter Langguth. (2013) Ion Pairing with Bile Salts Modulates Intestinal Permeability and Contributes to Food–Drug Interaction of BCS Class III Compound Trospium Chloride. Molecular Pharmaceutics 10:11, pages 3989-3996.
Crossref
Christine A Houghton, Robert G Fassett & Jeff S Coombes. (2013) Sulforaphane: translational research from laboratory bench to clinic. Nutrition Reviews 71:11, pages 709-726.
Crossref
Karen M. VanderMolen, Nadja B. Cech, Mary F. Paine & Nicholas H. Oberlies. (2013) Rapid Quantitation of Furanocoumarins and Flavonoids in Grapefruit Juice using Ultra‐Performance Liquid Chromatography. Phytochemical Analysis 24:6, pages 654-660.
Crossref
David J. Greenblatt, Jerold S. Harmatz, Nikhilesh N. Singh, Thomas Roth, Stephen C. Harris & Ram P. Kapil. (2013) Influence of food on pharmacokinetics of zolpidem from fast dissolving sublingual zolpidem tartrate tablets. The Journal of Clinical Pharmacology, pages n/a-n/a.
Crossref
Christina S. Won, Tian Lan, Karen M. VanderMolen, Paul A. Dawson, Nicholas H. Oberlies, Wilbur W. Widmer, Yolanda V. Scarlett & Mary F. Paine. (2013) A Modified Grapefruit Juice Eliminates Two Compound Classes as Major Mediators of the Grapefruit Juice-Fexofenadine Interaction: An In Vitro-In Vivo “Connect”. The Journal of Clinical Pharmacology 53:9, pages 982-990.
Crossref
Matthias Hoch, Petra Hoever, Rudolf Theodor & Jasper Dingemanse. (2013) Almorexant effects on CYP3A4 activity studied by its simultaneous and time-separated administration with simvastatin and atorvastatin. European Journal of Clinical Pharmacology 69:6, pages 1235-1245.
Crossref
Ilaria Peluso, Anna Raguzzini & Mauro Serafini. (2013) Effect of flavonoids on circulating levels of TNF-α and IL-6 in humans: A systematic review and meta-analysis. Molecular Nutrition & Food Research 57:5, pages 784-801.
Crossref
Michael J. Hanley, Gina Masse, Jerold S. Harmatz, Paul F. Cancalon, Gregory G. Dolnikowski, Michael H. Court & David J. Greenblatt. (2013) Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. British Journal of Clinical Pharmacology 75:4, pages 1041-1052.
Crossref
I Straub, F Mohr, J Stab, M Konrad, SE Philipp, J Oberwinkler & M Schaefer. (2013) Citrus fruit and fabacea secondary metabolites potently and selectively block TRPM 3 . British Journal of Pharmacology 168:8, pages 1835-1850.
Crossref
Maarit J. Rein, Mathieu Renouf, Cristina Cruz-Hernandez, Lucas Actis-Goretta, Sagar K. Thakkar & Marcia da Silva Pinto. (2013) Bioavailability of bioactive food compounds: a challenging journey to bioefficacy. British Journal of Clinical Pharmacology 75:3, pages 588-602.
Crossref
Matthias Hoch, Petra Hoever, Federica Alessi, Rudolf Theodor & Jasper Dingemanse. (2012) Pharmacokinetic interactions of almorexant with midazolam and simvastatin, two CYP3A4 model substrates, in healthy male subjects. European Journal of Clinical Pharmacology 69:3, pages 523-532.
Crossref
Kenta YoshidaKazuya MaedaYuichi Sugiyama. (2013) Hepatic and Intestinal Drug Transporters: Prediction of Pharmacokinetic Effects Caused by Drug-Drug Interactions and Genetic Polymorphisms. Annual Review of Pharmacology and Toxicology 53:1, pages 581-612.
Crossref
Ole D. Wolthers. (2013) Bilastine: A New Nonsedating Oral H1 Antihistamine for Treatment of Allergic Rhinoconjunctivitis and Urticaria. BioMed Research International 2013, pages 1-6.
Crossref
Neil J. Stone. 2013. Cardiovascular Therapeutics: A Companion to Braunwald's Heart Disease. Cardiovascular Therapeutics: A Companion to Braunwald's Heart Disease 421 433 .
Gwendolyn A. McMillin & Kamisha L. Johnson-Davis. 2013. Accurate Results in the Clinical Laboratory. Accurate Results in the Clinical Laboratory 195 211 .
M J Hanley, G Masse, J S Harmatz, M H Court & D J Greenblatt. (2012) Pomegranate Juice and Pomegranate Extract Do Not Impair Oral Clearance of Flurbiprofen in Human Volunteers: Divergence From In Vitro Results. Clinical Pharmacology & Therapeutics 92:5, pages 651-657.
Crossref
Christina S. Won, Nicholas H. Oberlies & Mary F. Paine. (2012) Mechanisms underlying food–drug interactions: Inhibition of intestinal metabolism and transport. Pharmacology & Therapeutics 136:2, pages 186-201.
Crossref
Suman Wason, Jennifer L. DiGiacinto & Matthew W. Davis. (2012) Effects of Grapefruit and Seville Orange Juices on the Pharmacokinetic Properties of Colchicine in Healthy Subjects. Clinical Therapeutics 34:10, pages 2161-2173.
Crossref
Theoharis C. Theoharides & Shahrzad Asadi. (2012) Unwanted Interactions Among Psychotropic Drugs and Other Treatments for Autism Spectrum Disorders. Journal of Clinical Psychopharmacology 32:4, pages 437-440.
Crossref
Caroline H. Johnson & Frank J. Gonzalez. (2012) Challenges and opportunities of metabolomics. Journal of Cellular Physiology 227:8, pages 2975-2981.
Crossref
Marko A. Peltoniemi, Teijo I. Saari, Nora M. Hagelberg, Kari Laine, Pertti J. Neuvonen & Klaus T. Olkkola. (2012) S-ketamine concentrations are greatly increased by grapefruit juice. European Journal of Clinical Pharmacology 68:6, pages 979-986.
Crossref
Sam Rebello, Sally Zhao, Sam Hariry, Marion Dahlke, Natalya Alexander, Arpine Vapurcuyan, Imad Hanna & Venkateswar Jarugula. (2011) Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects. European Journal of Clinical Pharmacology 68:5, pages 697-708.
Crossref
Artur Pałasz, Anna Wiaderkiewicz, Ryszard Wiaderkiewicz, Piotr Czekaj, Beata Czajkowska, Tomasz Lebda-Wyborny, Aneta Piwowarczyk & Aleksandra Bryzek. (2011) Age-related changes in the mRNA levels of CYP1A1, CYP2B1/2 and CYP3A1 isoforms in rat small intestine. Genes & Nutrition 7:2, pages 197-207.
Crossref
Caroline H. JohnsonAndrew D. PattersonJeffrey R. IdleFrank J. Gonzalez. (2012) Xenobiotic Metabolomics: Major Impact on the Metabolome. Annual Review of Pharmacology and Toxicology 52:1, pages 37-56.
Crossref
Susan E. Shoaf, Suresh Mallikaarjun & Patricia Bricmont. (2011) Effect of grapefruit juice on the pharmacokinetics of tolvaptan, a non-peptide arginine vasopressin antagonist, in healthy subjects. European Journal of Clinical Pharmacology 68:2, pages 207-211.
Crossref
Takehiko Yasuji, Hiromu Kondo & Kazuhiro Sako. (2012) The effect of food on the oral bioavailability of drugs: a review of current developments and pharmaceutical technologies for pharmacokinetic control. Therapeutic Delivery 3:1, pages 81-90.
Crossref
Andrew Somogyi, Yoon K. Loke, Albert Ferro, Lionel D. Lewis, Adam F. Cohen & James M. Ritter. (2012) Editors' pick 2011. British Journal of Clinical Pharmacology 73:1, pages 4-8.
Crossref
T. K. LimT. K. Lim. 2012. Edible Medicinal And Non-Medicinal Plants. Edible Medicinal And Non-Medicinal Plants 755 785 .
Patrick Reddy, David Ellington, Yiliang Zhu, Immo Zdrojewski, Sarah J. Parent, Jerold S. Harmatz, Hartmut Derendorf, David J. Greenblatt & Kevin Browne Jr. (2011) Serum concentrations and clinical effects of atorvastatin in patients taking grapefruit juice daily. British Journal of Clinical Pharmacology 72:3, pages 434-441.
Crossref
Lourdes Rodríguez-Fragoso, José Luis Martínez-Arismendi, Danae Orozco-Bustos, Jorge Reyes-Esparza, Eliseo Torres & Scott W. Burchiel. (2011) Potential Risks Resulting from Fruit/Vegetable-Drug Interactions: Effects on Drug-Metabolizing Enzymes and Drug Transporters. Journal of Food Science 76:4, pages R112-R124.
Crossref

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