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The influence of pharmacogenetics and cofactors on clinical outcomes in kidney transplantation

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Pages 731-743 | Published online: 25 Mar 2011

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Tsvetelin Lukanov, Milena Ivanova, Petya Yankova, Bushra Al Hadra, Anastasiya Mihaylova, Marianka Genova, Dobrin Svinarov & Elisaveta Naumova. (2022) Impact of CYP3A7, CYP2D6 and ABCC2/ABCC3 polymorphisms on tacrolimus steady state concentrations in Bulgarian kidney transplant recipients. Biotechnology & Biotechnological Equipment 36:1, pages 362-369.
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Chi Chiu Mok. (2017) Therapeutic monitoring of the immuno-modulating drugs in systemic lupus erythematosus. Expert Review of Clinical Immunology 13:1, pages 35-41.
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Karolína Hronová, Martin Šíma, Svatopluk Světlík, Olga Matoušková & Ondřej Slanař. (2014) Pharmacogenetics and immunosuppressive drugs. Expert Review of Clinical Pharmacology 7:6, pages 821-835.
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Articles from other publishers (28)

Fahadul Islam, Md. Rezaul Islam, Mohamed H. Nafady, Md. Faysal, Sharuk L. Khan, Mehrukh Zehravi, Talha Bin Emran & Md. Habibur Rahman. 2023. Pharmacogenomics. Pharmacogenomics 323 344 .
S. Djabarouti, P. Mora, M. Lahouati, M. Gigan, N. d’Houdain, B. Sourisseau, J. Chambord & F. Xuereb. (2022) Intérêt des dosages pharmacologiques d’immunosuppresseurs et immunomodulateurs dans la prise en charge des maladies autoimmunes. La Revue de Médecine Interne 43:7, pages 412-418.
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Fang Cheng, Qiang Li, Jinglin Wang, Fang Zeng & Yu Zhang. (2021) Effects and safety evaluation of Wuzhi Capsules combined with tacrolimus for the treatment of kidney transplantation recipients. Journal of Clinical Pharmacy and Therapeutics 46:6, pages 1636-1649.
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Daniel A. Brazeau, Kristopher Attwood, Calvin J. Meaney, Gregory E. Wilding, Joseph D. Consiglio, Shirley S. Chang, Aijaz Gundroo, Rocco C. Venuto, Louise Cooper & Kathleen M. Tornatore. (2020) Beyond Single Nucleotide Polymorphisms: CYP3A5∗3∗6∗7 Composite and ABCB1 Haplotype Associations to Tacrolimus Pharmacokinetics in Black and White Renal Transplant Recipients. Frontiers in Genetics 11.
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Desmond Y H Yap, Chun Hay Tam, Susan Yung, Sunny Wong, Colin S O Tang, Temy M Y Mok, Catherine K Y Yuen, Maggie K M Ma, Chak Sing Lau & Tak Mao Chan. (2020) Pharmacokinetics and pharmacogenomics of mycophenolic acid and its clinical correlations in maintenance immunosuppression for lupus nephritis. Nephrology Dialysis Transplantation 35:5, pages 810-818.
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Sahar El-Shair, Mohammad Al Shhab, Khaled Zayed, Moaath Alsmady & Malek Zihlif. (2019) Association Between CYP3A4 and CYP3A5 Genotypes and Cyclosporine's Blood Levels and Doses among Jordanian Kidney Transplanted Patients. Current Drug Metabolism 20:8, pages 682-694.
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. Experimental and Clinical Transplantation 16:3.
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José Pablo Werba, Shingen Misaka, Monica Gianna Giroli, Kenju Shimomura, Manuela Amato, Niccolò Simonelli, Lorenzo Vigo & Elena Tremoli. (2018) Update of green tea interactions with cardiovascular drugs and putative mechanisms. Journal of Food and Drug Analysis 26:2, pages S72-S77.
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Jian-Hua Liao, Chang-Can Li, Shao-Han Wu, Jun-Wei Fan, Hai-Tao Gu & Zhao-Wen Wang. (2017) Gene Variations of Sixth Complement Component Affecting Tacrolimus Metabolism in Patients with Liver Transplantation for Hepatocellular Carcinoma. Chinese Medical Journal 130:14, pages 1670-1676.
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Erika Y. Tamashiro, Claudia R. Felipe, Fabiana D.V. Genvigir, Alice C. Rodrigues, Antony B. Campos, Rosario D.C. Hirata, Helio Tedesco-SilvaJrJr & Jose O. Medina-Pestana. (2017) Influence of CYP3A4 and CYP3A5 polymorphisms on tacrolimus and sirolimus exposure in stable kidney transplant recipients . Drug Metabolism and Personalized Therapy 32:2, pages 89-95.
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Emily Brooks, Susan E. Tett, Nicole M. Isbel & Christine E. Staatz. (2016) Population Pharmacokinetic Modelling and Bayesian Estimation of Tacrolimus Exposure: Is this Clinically Useful for Dosage Prediction Yet?. Clinical Pharmacokinetics 55:11, pages 1295-1335.
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Dominique Barbolosi, Joseph Ciccolini, Bruno Lacarelle, Fabrice Barlési & Nicolas André. (2015) Computational oncology — mathematical modelling of drug regimens for precision medicine. Nature Reviews Clinical Oncology 13:4, pages 242-254.
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Lucie Pouché, Matthias Koitka, Jana Stojanova, Jean-Baptiste Woillard, Caroline Monchaud, Claire Villeneuve, Marie Essig, Julie Abraham, Yannick Le Meur, Jean-Phillippe Rerolle, Nassim Kamar, Lionel Rostaing, Pierre Merville, Peggy Gandia, Stephane Bouchet, Britt-Sabina Petersen, Pierre Marquet & Nicolas Picard. (2016) A candidate gene approach of the calcineurin pathway to identify variants associated with clinical outcomes in renal transplantation. Pharmacogenomics 17:4, pages 375-391.
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Xandra García-González, Teresa Cabaleiro, María José Herrero, Howard McLeod & Luis A. López-Fernández. (2016) Clinical implementation of pharmacogenetics. Drug Metabolism and Personalized Therapy 31:1, pages 9-16.
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Lin Yan, Yi Li, Jiang-Tao Tang, Yun-Fei An, Lan-Lan Wang & Yun-Ying Shi. (2016) Donor ABCB1 3435 C>T genetic polymorphisms influence early renal function in kidney transplant recipients treated with tacrolimus . Pharmacogenomics 17:3, pages 249-257.
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Rocco C. Venuto, Calvin J. Meaney, Shirley Chang, Nicolae Leca, Joseph D. Consiglio, Gregory E. Wilding, Daniel Brazeau, Aijaz Gundroo, Neha Nainani, Sarah E. Morse, Louise M. Cooper & Kathleen M. Tornatore. (2015) Association of Extrarenal Adverse Effects of Posttransplant Immunosuppression With Sex and ABCB1 Haplotypes. Medicine 94:37, pages e1315.
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Antje Albring, Laura Wendt, Nino Harz, Harald Engler, Benjamin Wilde, Andreas Kribben, Monika Lindemann, Manfred Schedlowski & Oliver Witzke. (2015) Relationship between pharmacokinetics and pharmacodynamics of calcineurin inhibitors in renal transplant patients. Clinical Transplantation 29:4, pages 294-300.
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Jiazhen Xing, Xiaoqing Zhang, Junwei Fan, Bin Shen, Tongyi Men & Jianning Wang. (2014) Association between interleukin-18 promoter variants and tacrolimus pharmacokinetics in Chinese renal transplant patients. European Journal of Clinical Pharmacology 71:2, pages 191-198.
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Zhaowen Wang, Shaohan Wu, Dawei Chen, Feng Guo, Lin Zhong, Junwei Fan & Zhihai Peng. (2014) Influence of TLR4 rs1927907 locus polymorphisms on tacrolimus pharmacokinetics in the early stage after liver transplantation. European Journal of Clinical Pharmacology 70:8, pages 925-931.
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Christine E. Staatz & Susan E. Tett. (2014) Pharmacology and toxicology of mycophenolate in organ transplant recipients: an update. Archives of Toxicology 88:7, pages 1351-1389.
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Jean-Baptiste Woillard, Nicolas Picard, Antoine Thierry, Guy Touchard & Pierre Marquet. (2014) Associations between polymorphisms in target, metabolism, or transport proteins of mycophenolate sodium and therapeutic or adverse effects in kidney transplant patients. Pharmacogenetics and Genomics 24:5, pages 256-262.
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Laure Elens, Rachida Bouamar, Nauras Shuker, Dennis A. Hesselink, Teun van Gelder & Ron H. N. van Schaik. (2014) Clinical implementation of pharmacogenetics in kidney transplantation: calcineurin inhibitors in the starting blocks. British Journal of Clinical Pharmacology 77:4, pages 715-728.
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Jean-Baptiste Woillard, Nassim Kamar, Sandra Coste, Lionel Rostaing, Pierre Marquet & Nicolas Picard. (2013) Effect of CYP3A4*22, POR*28, and PPARA rs4253728 on Sirolimus In Vitro Metabolism and Trough Concentrations in Kidney Transplant Recipients. Clinical Chemistry 59:12, pages 1761-1769.
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Mercè Brunet, Olga Millán & Jaume Martorell. (2013) Donor–recipient genetic diversity: the role of
pharmacogenomics in kidney transplantation. Pharmacogenomics 14:12, pages 1369-1372.
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Inés Llaudó, Helena Colom, Pepita Giménez-Bonafé, Joan Torras, Anna Caldés, Maria Sarrias, Josep Mª Cruzado, Federico Oppenheimer, Jaime Sánchez-Plumed, Miguel Ángel Gentil, Henrik Ekberg, Josep Mª Grinyó & Núria Lloberas. (2013) Do drug transporter (ABCB1) SNPs and P-glycoprotein function influence cyclosporine and macrolides exposure in renal transplant patients? Results of the pharmacogenomic substudy within the symphony study. Transplant International 26:2, pages 177-186.
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Yunying Shi, Yi Li, Jiangtao Tang, Junlong Zhang, Yuangao Zou, Bei Cai & Lanlan Wang. (2013) Influence of CYP3A4, CYP3A5 and MDR-1 polymorphisms on tacrolimus pharmacokinetics and early renal dysfunction in liver transplant recipients. Gene 512:2, pages 226-231.
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Yi Li, Xin Hu, Bei Cai, Jie Chen, Yangjuan Bai, Jiangtao Tang, Yun Liao & Lanlan Wang. (2012) Meta-analysis of the effect of MDR1 C3435 polymorphism on tacrolimus pharmacokinetics in renal transplant recipients. Transplant Immunology 27:1, pages 12-18.
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Christine E. Staatz & Susan E. Tett. (2011) Maximum A Posteriori Bayesian Estimation of Mycophenolic Acid Area Under the Concentration-Time Curve: Is This Clinically Useful for Dosage Prediction Yet?. Clinical Pharmacokinetics 50:12, pages 759-772.
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