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Bioactivation of herbal constituents: simple alerts in the complex system

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Pages 989-1007 | Published online: 24 May 2011

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Amandine Nachtergael, M?lanie Poivre, Alexandra Belayew & Pierre Duez. (2015) In vitro genotoxicity tests point to an unexpected and harmful effect of a Magnolia and Aristolochia association. Journal of Ethnopharmacology 174, pages 178-186.
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Guang-You Ma, Yun-Feng Cao, Cui-Min Hu, Zhong-Ze Fang, Xiao-Yu Sun, Mo Hong & Zhi-Tu Zhu. (2014) Comparison of Inhibition Capability of Scutellarein and Scutellarin Towards Important Liver UDP-Glucuronosyltransferase (UGT) Isoforms. Phytotherapy Research 28:3, pages 382-386.
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Jean-de-Dieu Tamokou & Victor Kuete. 2014. Toxicological Survey of African Medicinal Plants. Toxicological Survey of African Medicinal Plants 135 180 .
Jue Zhou, Moustapha Ouedraogo, Fan Qu & Pierre Duez. (2013) Potential Genotoxicity of Traditional Chinese Medicinal Plants and Phytochemicals: An Overview. Phytotherapy Research 27:12, pages 1745-1755.
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Yin‐Peng Huang, Yun‐Feng Cao, Zhong‐Ze Fang, Yan‐Yan Zhang, Cui‐Min Hu, Xiao‐Yu Sun, Zhen‐Wen Yu, Xu Zhu, Mo Hong, Lu Yang & Hong‐Zhi Sun. (2012) Glycyrrhetinic Acid Exhibits Strong Inhibitory Effects Towards UDP‐Glucuronosyltransferase (UGT) 1A3 and 2B7. Phytotherapy Research 27:9, pages 1358-1361.
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Ya-Jun He, Zhong-Ze Fang, Guang-Bo Ge, Peng Jiang, Hui-Zi Jin, Wei-Dong Zhang & Ling Yang. (2013) The Inhibitory Effect of 20( S )-Protopanaxatriol (ppt) Towards UGT1A1 and UGT2B7 . Phytotherapy Research 27:4, pages 628-632.
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Ming Cong, Cui-Min Hu, Yun-Feng Cao, Zhong-Ze Fang, Shu-Hong Tang, Jia-Rui Wang & Jun-Sheng Luo. (2013) Cryptotanshinone and dihydrotanshinone I exhibit strong inhibition towards human liver microsome (HLM)-catalyzed propofol glucuronidation. Fitoterapia 85, pages 109-113.
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Cong Liu, Yun-Feng Cao, Zhong-Ze Fang, Yan-Yan Zhang, Cui-Min Hu, Xiao-Yu Sun, Ting Huang, Jia Zeng, Xu-Ran Fan & Mo Hong. (2012) Strong inhibition of deoxyschizandrin and schisantherin A toward UDP-glucuronosyltransferase (UGT) 1A3 indicating UGT inhibition-based herb?drug interaction. Fitoterapia 83:8, pages 1415-1419.
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Zhong‐Ze Fang, Kristopher W Krausz, Fei Li, Jie Cheng, Naoki Tanaka & Frank J Gonzalez. (2012) Metabolic map and bioactivation of the anti‐tumour drug noscapine. British Journal of Pharmacology 167:6, pages 1271-1286.
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Moustapha Ouedraogo, Thomas Baudoux, Caroline Stévigny, Joëlle Nortier, Jean-Marie Colet, Thomas Efferth, Fan Qu, Jue Zhou, Kelvin Chan, Debbie Shaw, Olavi Pelkonen & Pierre Duez. (2012) Review of current and “omics” methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms. Journal of Ethnopharmacology 140:3, pages 492-512.
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Stuart M Brierley & Olaf Kelber. (2011) Use of natural products in gastrointestinal therapies. Current Opinion in Pharmacology 11:6, pages 604-611.
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