Citations (59)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (12)
Frank M. C. Besag, Dave Berry, Michael J. Vasey & Philip N. Patsalos. (2023) Drug-drug interactions between antiseizure medications and antipsychotic medications: a narrative review and expert opinion. Expert Opinion on Drug Metabolism & Toxicology 19:11, pages 829-847.
Read now
Read now
Marco Mula. (2023) Impact of psychiatric comorbidities on the treatment of epilepsies in adults. Expert Review of Neurotherapeutics 0:0, pages 1-10.
Read now
Read now
Carlos De Las Cuevas, Emilio J. Sanz & Jose de Leon. (2022) Respiratory aspiration during treatment with benzodiazepines, antiepileptic and antidepressant drugs in the pharmacovigilance database from VigiBase. Expert Opinion on Drug Metabolism & Toxicology 18:9, pages 541-553.
Read now
Read now
Nicolas Simon, Romain Torrents & Jean-Michel Azorin. (2022) Comorbidities and the right dose: antipsychotics. Expert Opinion on Drug Metabolism & Toxicology 18:7-8, pages 507-518.
Read now
Read now
Georgios Schoretsanitis, Kristina M. Deligiannidis, Michael Paulzen, Edoardo Spina & Jose de Leon. (2022) Drug-drug interactions between psychotropic medications and oral contraceptives. Expert Opinion on Drug Metabolism & Toxicology 18:6, pages 395-411.
Read now
Read now
Yan-Nan Zang, Wei Guo, Fang Dong, An-Ning Li, Jose de Leon & Can-Jun Ruan. (2022) Published population pharmacokinetic models of valproic acid in adult patients: a systematic review and external validation in a Chinese sample of inpatients with bipolar disorder. Expert Review of Clinical Pharmacology 15:5, pages 621-635.
Read now
Read now
Ian McGrane, Edoardo Spina, Christoph Hiemke & Jose de Leon. (2022) Pharmacokinetic drug interactions with oral haloperidol in adults: dose correction factors from a combined weighted analysis. Expert Opinion on Drug Metabolism & Toxicology 18:2, pages 135-149.
Read now
Read now
C. B. Eap, G. Gründer, P. Baumann, N. Ansermot, A. Conca, E. Corruble, S. Crettol, M. L. Dahl, J. de Leon, C. Greiner, O. Howes, E. Kim, R. Lanzenberger, J. H. Meyer, R. Moessner, H. Mulder, D. J. Müller, M. Reis, P. Riederer, H. G. Ruhe, O. Spigset, E. Spina, B. Stegman, W. Steimer, J. Stingl, S. Suzen, H. Uchida, S. Unterecker, F. Vandenberghe & C. Hiemke. (2021) Tools for optimising pharmacotherapy in psychiatry (therapeutic drug monitoring, molecular brain imaging and pharmacogenetic tests): focus on antidepressants. The World Journal of Biological Psychiatry 22:8, pages 561-628.
Read now
Read now
Georgios Schoretsanitis, John M. Kane, Can-Jun Ruan, Edoardo Spina, Christoph Hiemke & Jose de Leon. (2019) A comprehensive review of the clinical utility of and a combined analysis of the clozapine/norclozapine ratio in therapeutic drug monitoring for adult patients. Expert Review of Clinical Pharmacology 12:7, pages 603-621.
Read now
Read now
Edoardo Spina, Christoph Hiemke & Jose de Leon. (2016) Assessing drug-drug interactions through therapeutic drug monitoring when administering oral second-generation antipsychotics. Expert Opinion on Drug Metabolism & Toxicology 12:4, pages 407-422.
Read now
Read now
Domenico Italiano, Edoardo Spina & Jose de Leon. (2014) Pharmacokinetic and pharmacodynamic interactions between antiepileptics and antidepressants. Expert Opinion on Drug Metabolism & Toxicology 10:11, pages 1457-1489.
Read now
Read now
Edoardo Spina & Jose de Leon. (2014) Clinically relevant interactions between newer antidepressants and second-generation antipsychotics. Expert Opinion on Drug Metabolism & Toxicology 10:5, pages 721-746.
Read now
Read now
Articles from other publishers (47)
Francesco Pisani, Laura Rosa Pisani, Maria Antonietta Barbieri, Jose de Leon & Edoardo Spina. (2023) Optimization of Therapy in Patients with Epilepsy and Psychiatric
Comorbidities: Key Points. Current Neuropharmacology 21:8, pages 1755-1766.
Crossref
Crossref
V. Sandroni, M. Korostelev, N. Chaumartin, A. Frajerman & P.-A. Hauseux. (2023) Confusion in patient with Lamotrigine-Aripiprazole treatment: A case report. L'Encéphale 49:4, pages 437-439.
Crossref
Crossref
Masakazu Hatano, Kaho Yamada, Haruna Matsuzaki, Rina Yokoi, Takeo Saito & Shigeki Yamada. (2023) Analysis of clozapine-induced seizures using the Japanese Adverse Drug Event Report database. PLOS ONE 18:6, pages e0287122.
Crossref
Crossref
Jing Ding, Yan Zhang, Yan Zhang, Liu Yang, Suo Zhang, Xiaohua Cui, Zhuocheng Meng, Yajuan Li & Huan Xing. (2022) Effects of Age, Sex, and Comedication on the Plasma Concentrations of Olanzapine in Chinese Patients With Schizophrenia Based on Therapeutic Drug Monitoring Data. Journal of Clinical Psychopharmacology 42:6, pages 552-559.
Crossref
Crossref
Jonathan G. Leung, Jose de Leon, Mark A. Frye, Balwinder Singh, Robert O. Cotes & Susan L. McElroy. (2022) The Modernization of Clozapine. Journal of Clinical Psychopharmacology 42:6, pages 565-580.
Crossref
Crossref
Marco Mula, Honor Coleman & Sarah J. Wilson. (2022) Neuropsychiatric and Cognitive Comorbidities in Epilepsy. CONTINUUM: Lifelong Learning in Neurology 28:2, pages 457-482.
Crossref
Crossref
N. Charfi, S. Omri, N. Smaoui, R. Feki, L. Zouari, J. Ben Thabet, M. Maâlej Bouali & M. Maâlej. (2021) Le maniement des psychotropes dans les maladies du système nerveux central. L'Encéphale 47:5, pages 461-469.
Crossref
Crossref
Marta Karaźniewicz-Łada, Anna K. Główka, Aniceta A. Mikulska & Franciszek K. Główka. (2021) Pharmacokinetic Drug–Drug Interactions among Antiepileptic Drugs, Including CBD, Drugs Used to Treat COVID-19 and Nutrients. International Journal of Molecular Sciences 22:17, pages 9582.
Crossref
Crossref
Carlos Parga-Lozano & Nohemi Santodomingo. (2021) Stevens-Johnson syndrome: relation with phenytoin and carbamazepine associated with HLA and CYP polymorphism in Colombia. Pharmacy & Pharmacology International Journal 9:3, pages 103-107.
Crossref
Crossref
Kristen Cannon. 2021. Absolute Geriatric Psychiatry Review. Absolute Geriatric Psychiatry Review
295
310
.
Edoardo Spina, Maria Antonietta Barbieri, Giuseppe Cicala & Jose de Leon. (2020) Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents. Pharmaceuticals 13:12, pages 439.
Crossref
Crossref
Shu-hua DengZhan-Zhang Wang, Hao-Yang Lu, Lu Li, Jin-Qing Hu, Xiu-Qing Zhu, Huan-Shan Xie, Hong-Zhen Chen, Ming Zhang, Xiao-Jia Ni, Chang Qiu, De-Wei ShangYu-Guan Wen. (2020) A Retrospective Analysis of Steady-State Olanzapine Concentrations in Chinese Patients Using Therapeutic Drug Monitoring: Effects of Valproate and Other Factors. Therapeutic Drug Monitoring 42:4, pages 636-642.
Crossref
Crossref
James W. Wheless, Stephen P. Fulton & Basanagoud D. Mudigoudar. (2020) Dravet Syndrome: A Review of Current Management. Pediatric Neurology 107, pages 28-40.
Crossref
Crossref
Jose de Leon, Can-Jun Ruan, Georgios Schoretsanitis & Carlos De las Cuevas. (2020) A Rational Use of Clozapine Based on Adverse Drug Reactions, Pharmacokinetics, and Clinical Pharmacopsychology. Psychotherapy and Psychosomatics 89:4, pages 200-214.
Crossref
Crossref
Marit Tveito, Robert Løvsletten Smith, Gudrun Høiseth & Espen Molden. (2019) The Effect of Valproic Acid on Olanzapine Serum Concentration. Journal of Clinical Psychopharmacology 39:6, pages 561-566.
Crossref
Crossref
Niruj Agrawal & Marco Mula. (2019) Treatment of psychoses in patients with epilepsy: an update. Therapeutic Advances in Psychopharmacology 9, pages 204512531986296.
Crossref
Crossref
Jose de Leon. (2019) Why Do You Keep Telling Me That Drug-Drug Interactions Are Important in Psychopharmacology When I Do Not See Them in My Clinical Practice?. Journal of Clinical Psychopharmacology 39:1, pages 1-4.
Crossref
Crossref
Leif HommersMagdalena ScharlGudrun HefnerMatthias HohnerMatthias FischerBruno PfuhlmannJürgen DeckertStefan Unterecker. (2018) Comedication of Valproic Acid Is Associated With Increased Metabolism of Clozapine. Journal of Clinical Psychopharmacology 38:3, pages 188-192.
Crossref
Crossref
Jose de Leon & Edoardo Spina. (2018) Possible Pharmacodynamic and Pharmacokinetic Drug-Drug Interactions That Are Likely to Be Clinically Relevant and/or Frequent in Bipolar Disorder. Current Psychiatry Reports 20:3.
Crossref
Crossref
Sarvesh Singh, Hafeez Ahmad & Alexander Panickacheril John. (2017) Lurasidone associated neutropenia. Australian & New Zealand Journal of Psychiatry 51:10, pages 1055-1055.
Crossref
Crossref
L. Hernández & K. Marín. (2017) Interacciones medicamentosas de los anticonvulsivantes de primera línea con antipsicóticos y/o antidepresivos. Repertorio de Medicina y Cirugía 26:2, pages 78-84.
Crossref
Crossref
Hazel Yousra, Lebain Pierrick, Lecardeur Laurent & Debruyne Danièle. (2016) Interaction between clozapine and oxcarbazepine: a case report. Therapeutic Advances in Psychopharmacology 7:2, pages 95-99.
Crossref
Crossref
Michele Fornaro, Domenico De Berardis, Giampaolo Perna, Marco Solmi, Nicola Veronese, Laura Orsolini, Elisabetta Filomena Buonaguro, Felice Iasevoli, Cristiano André Köhler, André Ferrer Carvalho & Andrea de Bartolomeis. (2017) Lurasidone in the Treatment of Bipolar Depression: Systematic Review of Systematic Reviews. BioMed Research International 2017, pages 1-17.
Crossref
Crossref
Georgios Schoretsanitis, Ekkehard Haen, Gerhard Gründer, Benedikt Stegmann, Koen R. J. Schruers, Christoph Hiemke, Sarah E. Lammertz & Michael Paulzen. (2016) Pharmacokinetic Drug-Drug Interactions of Mood Stabilizers and Risperidone in Patients Under Combined Treatment. Journal of Clinical Psychopharmacology 36:6, pages 554-561.
Crossref
Crossref
W. Timothy Garvey, Jeffrey I. Mechanick, Elise M. Brett, Alan J. Garber, Daniel L. Hurley, Ania M. Jastreboff, Karl Nadolsky, Rachel Pessah-Pollack & Raymond Plodkowski. (2016) American Association of Clinical Endocrinologists and American College of Endocrinology Comprehensive Clinical Practice Guidelines For Medical Care of Patients with Obesity. Endocrine Practice 22, pages 1-203.
Crossref
Crossref
Marco Mula. (2016) The pharmacological management of psychiatric comorbidities in patients with epilepsy. Pharmacological Research 107, pages 147-153.
Crossref
Crossref
Edoardo Spina, Francesco Pisani & Jose de Leon. (2016) Clinically significant pharmacokinetic drug interactions of antiepileptic drugs with new antidepressants and new antipsychotics. Pharmacological Research 106, pages 72-86.
Crossref
Crossref
Hee Jung Park & Jung Yoon Kim. (2016) Incidence of Neutropenia With Valproate and Quetiapine Combination Treatment in Subjects With Acquired Brain Injuries. Archives of Physical Medicine and Rehabilitation 97:2, pages 183-188.
Crossref
Crossref
Nasratullah Wahidi, Katie M. Johnson, Allen Brenzel & Jose de Leon. (2016) Two Sudden and Unexpected Deaths of Patients with Schizophrenia Associated with Intramuscular Injections of Antipsychotics and Practice Guidelines to Limit the Use of High Doses of Intramuscular Antipsychotics. Case Reports in Psychiatry 2016, pages 1-14.
Crossref
Crossref
Edoardo Spina & Domenico Italiano. 2015. The Treatment of Epilepsy. The Treatment of Epilepsy
344
359
.
Jennifer Miller, Heidi Wehring, Robert P. McMahon, Bethany A. DiPaula, Raymond C. Love, Ayodele Antoinette Morris, Heather Raley, Stephanie Feldman & Deanna L. Kelly. (2015) Urine testing for antipsychotics: a pilot trial for a method to determine detection levels. Human Psychopharmacology: Clinical and Experimental 30:5, pages 350-355.
Crossref
Crossref
Jose de Leon. (2015) The effects of antiepileptic inducers in neuropsychopharmacology, a neglected issue. Part II: Pharmacological issues and further understanding. Revista de Psiquiatría y Salud Mental (English Edition) 8:3, pages 167-188.
Crossref
Crossref
Jose de Leon. (2015) Efectos de los inductores antiepilépticos en la neuropsicofarmacología: una cuestión ignorada. Parte II: cuestiones farmacológicas y comprensión adicional. Revista de Psiquiatría y Salud Mental 8:3, pages 167-188.
Crossref
Crossref
Nancy J. Butcher, Wai Lun Alan Fung, Laura Fitzpatrick, Alina Guna, Danielle M. Andrade, Anthony E. Lang, Eva W. C. Chow & Anne S. Bassett. (2018) Response to clozapine in a clinically identifiable subtype of
schizophrenia. British Journal of Psychiatry 206:6, pages 484-491.
Crossref
Crossref
Xian-Bin Li, Yi-Lang Tang, Chuan-Yue Wang & Jose de Leon. (2015) Clozapine for treatment-resistant bipolar disorder: a systematic review. Bipolar Disorders 17:3, pages 235-247.
Crossref
Crossref
Jose de Leon. (2015) The effects of antiepileptic inducers in neuropsychopharmacology, a neglected issue. Part I: A summary of the current state for clinicians. Revista de Psiquiatría y Salud Mental (English Edition) 8:2, pages 97-115.
Crossref
Crossref
Jose de Leon. (2015) Efectos de los inductores antiepil?pticos en la neuropsicofarmacolog?a: una cuesti?n ignorada. Parte I: Resumen para los cl?nicos de la situaci?n actual. Revista de Psiquiatr?a y Salud Mental 8:2, pages 97-115.
Crossref
Crossref
Edoardo Spina & Jose de Leon. (2014) Clinical applications of CYP genotyping in psychiatry. Journal of Neural Transmission 122:1, pages 5-28.
Crossref
Crossref
Jose de Leon. (2014) False-Negative Studies May Systematically Contaminate the Literature on the Effects of Inducers in Neuropsychopharmacology. Journal of Clinical Psychopharmacology 34:3, pages 291-296.
Crossref
Crossref
Jose de Leon. (2014) False-Negative Studies May Systematically Contaminate the Literature on the Effects of Inducers in Neuropsychopharmacology. Part I. Journal of Clinical Psychopharmacology 34:2, pages 177-183.
Crossref
Crossref
Jiang Wang, María Sánchez-Roselló, José Luis Aceña, Carlos del Pozo, Alexander E. Sorochinsky, Santos Fustero, Vadim A. Soloshonok & Hong Liu. (2013) Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011). Chemical Reviews 114:4, pages 2432-2506.
Crossref
Crossref
Isaac Schweitzer, Jerome Sarris, Virginia Tuckwell, Kay Maguire, Deidre Smith & Chee Ng. (2013) Aripiprazole as augmentation therapy in bipolar patients with current minor or subsyndromal mood symptoms. International Journal of Bipolar Disorders 1:1.
Crossref
Crossref
Amber Riesselman, Bryan Strobl, Andrew T. Cooley & Jose de Leon. (2013) A Case Report That Suggested That Aspirin’s Effects on Valproic Acid Metabolism May Contribute to Valproic Acid’s Inducer Effects on Clozapine Metabolism. Journal of Clinical Psychopharmacology 33:6, pages 812-814.
Crossref
Crossref
Andrea de Bartolomeis, Livia Avvisati, Felice Iasevoli & Carmine Tomasetti. (2013) Intracellular pathways of antipsychotic combined therapies: Implication for psychiatric disorders treatment. European Journal of Pharmacology 718:1-3, pages 502-523.
Crossref
Crossref
Anja Cerovecki, Richard Musil, Ansgar Klimke, Florian Seemüller, Ekkehard Haen, Rebecca Schennach, Kai-Uwe Kühn, Hans-Peter Volz & Michael Riedel. (2013) Withdrawal Symptoms and Rebound Syndromes Associated with Switching and Discontinuing Atypical Antipsychotics: Theoretical Background and Practical Recommendations. CNS Drugs 27:7, pages 545-572.
Crossref
Crossref
Jose de Leon, Edoardo Spina & Francisco J. Diaz. (2013) Clobazam Therapeutic Drug Monitoring. Therapeutic Drug Monitoring 35:1, pages 30-47.
Crossref
Crossref
Tore Haslemo, Kristine Olsen, Hilde Lunde & Espen Molden. (2012) Valproic Acid Significantly Lowers Serum Concentrations of Olanzapine—An Interaction Effect Comparable With Smoking. Therapeutic Drug Monitoring 34:5, pages 512-517.
Crossref
Crossref