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Improved brain uptake of peptide-based CNS drugs via alternative routes of administrations of its nanocarrier delivery systems: a promising strategy for CNS targeting delivery of peptides

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Christina Giannakou, Margriet VDZ Park, Wim H de Jong, Henk van Loveren, Rob J Vandebriel & Robert E Geertsma. (2016) A comparison of immunotoxic effects of nanomedicinal products with regulatory immunotoxicity testing requirements. International Journal of Nanomedicine 11, pages 2935-2952.
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Shiv Bahadur & Kamla Pathak. 2021. Direct Nose-to-Brain Drug Delivery. Direct Nose-to-Brain Drug Delivery 187 207 .
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Christina Giannakou, Kukka Aimonen, Louis van Bloois, Julia Catalán, Robert E Geertsma, Eric R Gremmer, Wim H de Jong, Peter HJ Keizers, Paul LWJ Schwillens, Rob J Vandebriel & Margriet VDZ Park. (2019) Sensitive method for endotoxin determination in nanomedicinal product samples. Nanomedicine 14:10, pages 1231-1246.
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Qianwen Wang, Shaohong Peng, Yue Hu, Chun-Ho Wong, Kin Ming Kwan, H.Y. Edwin Chan & Zhong Zuo. (2019) Efficient brain uptake and distribution of an expanded CAG RNA inhibitor DB213 via intranasal administration. European Journal of Pharmaceutical Sciences 127, pages 240-251.
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Mengbi Yang, Qian Zhang, Qianwen Wang, Kasper K. Sørensen, Josephine T. Boesen, Sum Yi Ma, Knud J. Jensen, Kin Ming Kwan, Jacky Chi Ki Ngo, Ho Yin Edwin Chan & Zhong Zuo. (2018) Brain-Targeting Delivery of Two Peptidylic Inhibitors for Their Combination Therapy in Transgenic Polyglutamine Disease Mice via Intranasal Administration. Molecular Pharmaceutics 15:12, pages 5781-5792.
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Qianwen Wang, Yufeng Zhang, Shuai Qian, Shaohong Peng, Qian Zhang, Chun-Ho Wong, H.Y. Edwin Chan & Zhong Zuo. (2016) Pharmacokinetics and brain uptake of HIV-1 replication inhibitor DB213 in Sprague-Dawley rats. Journal of Pharmaceutical and Biomedical Analysis 125, pages 41-47.
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