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Review

The pregnane X receptor: from bench to bedside

, MD PhD, , PhD & , PhD
Pages 895-908 | Published online: 15 Jul 2008

Keep up to date with the latest research on this topic with citation updates for this article.

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Huan Lan, Ying Zhang, Minqi Fan, Bingxin Wu & Caiyan Wang. (2023) Pregnane X receptor as a therapeutic target for cholestatic liver injury. Drug Metabolism Reviews 55:4, pages 371-387.
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Yue-Ming Wang, Sergio C Chai, Christopher T Brewer & Taosheng Chen. (2014) Pregnane X receptor and drug-induced liver injury. Expert Opinion on Drug Metabolism & Toxicology 10:11, pages 1521-1532.
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Yue-Ming Wang, Su Sien Ong, Sergio C Chai & Taosheng Chen. (2012) Role of CAR and PXR in xenobiotic sensing and metabolism. Expert Opinion on Drug Metabolism & Toxicology 8:7, pages 803-817.
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Olivier Fardel, Elise Kolasa & Marc Le Vee. (2012) Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics. Expert Opinion on Drug Metabolism & Toxicology 8:1, pages 29-46.
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Mariano Ferraresso, Stefano Turolo, Luciana Ghio, Amedea S. Tirelli, Mirco Belingheri, Roberta Villa, Elena Groppali & Alberto Edefonti. (2011) Association Between CYP3A5 Polymorphisms and Blood Pressure in Kidney Transplant Recipients Receiving Calcineurin Inhibitors. Clinical and Experimental Hypertension 33:6, pages 359-365.
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Xiaoyan Pang, Jie Cheng, Kristopher W. Krausz, De-an Guo & Frank J. Gonzalez. (2011) Pregnane X receptor-mediated induction of Cyp3a by black cohosh. Xenobiotica 41:2, pages 112-123.
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John YL Chiang. (2009) Hepatocyte nuclear factor 4α regulation of bile acid and drug metabolism. Expert Opinion on Drug Metabolism & Toxicology 5:2, pages 137-147.
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