1,367
Views
153
CrossRef citations to date
0
Altmetric
Reviews

In vitro models of the human epithelial airway barrier to study the toxic potential of particulate matter

, PhD, , &
Pages 1075-1089 | Published online: 04 Aug 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (14)

Maria João Bessa, Fátima Brandão, Fernanda Rosário, Luciana Moreira, Ana Teresa Reis, Vanessa Valdiglesias, Blanca Laffon, Sónia Fraga & João Paulo Teixeira. (2023) Assessing the in vitro toxicity of airborne (nano)particles to the human respiratory system: from basic to advanced models. Journal of Toxicology and Environmental Health, Part B 26:2, pages 67-96.
Read now
Xiaoli Ji, Yunhua Sheng, Ying Guan, Yinxia Li, Yuqiong Xu & Liming Tang. (2022) Evaluation of Calu-3 cell lines as an in vitro model to study the inhalation toxicity of flavoring extracts . Toxicology Mechanisms and Methods 32:3, pages 171-179.
Read now
Stephan Ehrmann, Otmar Schmid, Chantal Darquenne, Barbara Rothen-Rutishauser, Josue Sznitman, Lin Yang, Hana Barosova, Laurent Vecellio, Jolyon Mitchell & Nathalie Heuze-Vourc’h. (2020) Innovative preclinical models for pulmonary drug delivery research. Expert Opinion on Drug Delivery 17:4, pages 463-478.
Read now
Seraina Beyeler, Selina Steiner, Carlos Wotzkow, Stefan A. Tschanz, Amanuel Adhanom Sengal, Peter Wick, Beat Haenni, Marco P. Alves, Christophe von Garnier & Fabian Blank. (2020) Multi-walled carbon nanotubes activate and shift polarization of pulmonary macrophages and dendritic cells in an in vivo model of chronic obstructive lung disease. Nanotoxicology 14:1, pages 77-96.
Read now
Guanghe Wang, Wenjing Liu & Weimin Song. (2019) Toxicity assessment of electronic cigarettes. Inhalation Toxicology 31:7, pages 259-273.
Read now
Jose Zavala, Bridget O’Brien, Kim Lichtveld, Kenneth G. Sexton, Ivan Rusyn, Ilona Jaspers & William Vizuete. (2016) Assessment of biological responses of EpiAirway 3-D cell constructs versus A549 cells for determining toxicity of ambient air pollution. Inhalation Toxicology 28:6, pages 251-259.
Read now
Natalie Jeannet, Martin Fierz, Markus Kalberer, Heinz Burtscher & Marianne Geiser. (2015) Nano Aerosol Chamber for In-Vitro Toxicity (NACIVT) studies. Nanotoxicology 9:1, pages 34-42.
Read now
Nicole Schreiber, Michael Ströbele, Johannes Kopf, Renate Hochscheid, Elke Kotte, Petra Weber, Tanja Hansen, Henning Bockhorn & Bernd Müller. (2013) Lung Alterations Following Single or Multiple Low-Dose Carbon Black Nanoparticle Aspirations in Mice. Journal of Toxicology and Environmental Health, Part A 76:24, pages 1317-1332.
Read now
Martin J. D. Clift, David O. Raemy, Carola Endes, Zulqurnain Ali, Andrea D. Lehmann, Christina Brandenberger, Alke Petri-Fink, Peter Wick, Wolfgang J. Parak, Peter Gehr, Roel P. F. Schins & Barbara Rothen-Rutishauser. (2013) Can the Ames test provide an insight into nano-object mutagenicity? Investigating the interaction between nano-objects and bacteria. Nanotoxicology 7:8, pages 1373-1385.
Read now
Samir Dekali, Ariane Divetain, Thierry Kortulewski, Justine Vanbaelinghem, Christelle Gamez, Françoise Rogerieux, Ghislaine Lacroix & Patrice Rat. (2013) Cell cooperation and role of the P2X7 receptor in pulmonary inflammation induced by nanoparticles. Nanotoxicology 7:8, pages 1302-1314.
Read now
Eric Chau, Justin F. Galloway, Antoinette Nelson, Patrick N. Breysse, Denis Wirtz, Peter C. Searson & Venkataramana K. Sidhaye. (2013) Effect of modifying quantum dot surface charge on airway epithelial cell uptake in vitro . Nanotoxicology 7:6, pages 1143-1151.
Read now
Hui Xin Ong, Daniela Traini & Paul M Young. (2013) Pharmaceutical applications of the Calu-3 lung epithelia cell line. Expert Opinion on Drug Delivery 10:9, pages 1287-1302.
Read now
Brandi N. Snyder-Talkington, Yong Qian, Vincent Castranova & Nancy L. Guo. (2012) New Perspectives for in Vitro Risk Assessment of Multiwalled Carbon Nanotubes: Application of Coculture and Bioinformatics. Journal of Toxicology and Environmental Health, Part B 15:7, pages 468-492.
Read now
Emily J Swindle & Donna E Davies. (2011) Artificial airways for the study of respiratory disease. Expert Review of Respiratory Medicine 5:6, pages 757-765.
Read now

Articles from other publishers (139)

Nour Jaber & Sylvain Billet. (2024) How to use an in vitro approach to characterize the toxicity of airborne compounds. Toxicology in Vitro 94, pages 105718.
Crossref
Lyndsey Hendriks, Vera M. Kissling, Tina Buerki-Thurnherr & Denise M. Mitrano. (2023) Development of single-cell ICP-TOFMS to measure nanoplastics association with human cells. Environmental Science: Nano 10:12, pages 3439-3449.
Crossref
Mahshab Sheraz, Juhea Kim & Juran Kim. (2023) Nano/microplastics in indoor air: A critical review of synthesis routes for toxicity testing and preventative measure strategies. Process Safety and Environmental Protection 180, pages 274-304.
Crossref
Umesh K. Shandilya, Ankita Sharma, Ran Xu, Maria Malane M. Muniz & Niel A. Karrow. (2023) Evaluation of Immunomodulatory Effects of Fusarium Mycotoxins Using Bacterial Endotoxin-Stimulated Bovine Epithelial Cells and Macrophages in Co-Culture. Genes 14:11, pages 2014.
Crossref
Fobang Liu & Nga Lee Ng. 2023. Toxicity of Atmospheric Aerosols: Methodologies & Assays. Toxicity of Atmospheric Aerosols: Methodologies & Assays.
Yuanbao Zhang, Yiqun Mo, Yue Zhang, Jiali Yuan & Qunwei Zhang. (2023) MMP-3-mediated cleavage of OPN is involved in copper oxide nanoparticle-induced activation of fibroblasts. Particle and Fibre Toxicology 20:1.
Crossref
Barbara Rothen-Rutishauser, Matthew Gibb, Ruiwen He, Alke Petri-Fink & Christie M. Sayes. (2023) Human lung cell models to study aerosol delivery – considerations for model design and development. European Journal of Pharmaceutical Sciences 180, pages 106337.
Crossref
Luisana Di Cristo & Stefania Sabella. 2023. Cancer Cell Culture. Cancer Cell Culture 41 64 .
Yuanjie Zhang, Bin Liu, Zongming Liu & Jinkai Li. (2022) Research progress in the synthesis and biological application of quantum dots. New Journal of Chemistry 46:43, pages 20515-20539.
Crossref
Marjory Moreau, Jeff Fisher, Melvin E. Andersen, Asayah Barnwell, Sage Corzine, Aarati Ranade, Patrick D. McMullen & Scott D. Slattery. (2022) NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1,3-dichloropropene. Toxicology 481, pages 153340.
Crossref
Joshua D. Breidenbach, Benjamin W. French, Tamiya T. Gordon, Andrew L. Kleinhenz, Fatimah K. Khalaf, James C. Willey, Jeffrey R. Hammersley, R. Mark Wooten, Erin L. Crawford, Nikolai N. Modyanov, Deepak Malhotra, Justin G. Teeguarden, Steven T. Haller & David J. Kennedy. (2022) Microcystin-LR aerosol induces inflammatory responses in healthy human primary airway epithelium. Environment International 169, pages 107531.
Crossref
Jacek Baj, James Curtis Dring, Marcin Czeczelewski, Paweł Kozyra, Alicja Forma, Jolanta Flieger, Beata Kowalska, Grzegorz Buszewicz & Grzegorz Teresiński. (2022) Derivatives of Plastics as Potential Carcinogenic Factors: The Current State of Knowledge. Cancers 14:19, pages 4637.
Crossref
Aline Chary, Katherine Groff, Andreas O. Stucki, Servane Contal, Charlotte Stoffels, Sébastien Cambier, Monita Sharma, Arno C. Gutleb & Amy J. Clippinger. (2022) Maximizing the relevance and reproducibility of A549 cell culture using FBS-free media. Toxicology in Vitro 83, pages 105423.
Crossref
Laura Maria Azzurra Camassa, Elisabeth Elje, Espen Mariussen, Eleonora Marta Longhin, Maria Dusinska, Shan Zienolddiny-Narui & Elise Rundén-Pran. (2022) Advanced Respiratory Models for Hazard Assessment of Nanomaterials—Performance of Mono-, Co- and Tricultures. Nanomaterials 12:15, pages 2609.
Crossref
Ramzi Lakhdar, Sharon Mumby, Hisham Abubakar-Waziri, Alexandra Porter, Ian M. Adcock & Kian Fan Chung. (2022) Lung toxicity of particulates and gaseous pollutants using ex-vivo airway epithelial cell culture systems. Environmental Pollution 305, pages 119323.
Crossref
Svenja Offer, Elena Hartner, Sebastiano Di Bucchianico, Christoph Bisig, Stefanie Bauer, Jana Pantzke, Elias J. Zimmermann, Xin Cao, Stefanie Binder, Evelyn Kuhn, Anja Huber, Seongho Jeong, Uwe Käfer, Patrick Martens, Arunas Mesceriakovas, Jan Bendl, Ramona Brejcha, Angela Buchholz, Daniella Gat, Thorsten Hohaus, Narges Rastak, Gert Jakobi, Markus Kalberer, Tamara Kanashova, Yue Hu, Christoph Ogris, Annalisa Marsico, Fabian Theis, Michal Pardo, Thomas Gröger, Sebastian Oeder, Jürgen Orasche, Andreas Paul, Till Ziehm, Zhi-Hui Zhang, Thomas Adam, Olli Sippula, Martin Sklorz, Jürgen Schnelle-Kreis, Hendryk Czech, Astrid Kiendler-Scharr, Yinon Rudich & Ralf Zimmermann. (2022) Effect of Atmospheric Aging on Soot Particle Toxicity in Lung Cell Models at the Air–Liquid Interface: Differential Toxicological Impacts of Biogenic and Anthropogenic Secondary Organic Aerosols (SOAs). Environmental Health Perspectives 130:2.
Crossref
Pablo Fdez-Arroyabe, Ciro Salcines, Pavlos Kassomenos, Ana Santurtún & Tuukka Petäjä. (2022) Electric charge of atmospheric nanoparticles and its potential implications with human health. Science of The Total Environment 808, pages 152106.
Crossref
Maria João Bessa, Fátima Brandão, Paul H. B. Fokkens, Daan L. A. C. Leseman, A. John F. Boere, Flemming R. Cassee, Apostolos Salmatonidis, Mar Viana, Adriana Vulpoi, Simion Simon, Eliseo Monfort, João Paulo Teixeira & Sónia Fraga. (2021) In Vitro Toxicity of Industrially Relevant Engineered Nanoparticles in Human Alveolar Epithelial Cells: Air–Liquid Interface versus Submerged Cultures. Nanomaterials 11:12, pages 3225.
Crossref
Mabel Barreiro Carpio, Mohammadhossein Dabaghi, Julia Ungureanu, Martin R. Kolb, Jeremy A. Hirota & Jose Manuel Moran-Mirabal. (2021) 3D Bioprinting Strategies, Challenges, and Opportunities to Model the Lung Tissue Microenvironment and Its Function. Frontiers in Bioengineering and Biotechnology 9.
Crossref
Hana Barosova, Kirsty Meldrum, Bedia Begum Karakocak, Sandor Balog, Shareen H. Doak, Alke Petri-Fink, Martin J.D. Clift & Barbara Rothen-Rutishauser. (2021) Inter-laboratory variability of A549 epithelial cells grown under submerged and air-liquid interface conditions. Toxicology in Vitro 75, pages 105178.
Crossref
Maria Julia Altube, Lilen Ivonne Caimi, Cristian Huck-Iriart, Maria Jose Morilla & Eder Lilia Romero. (2021) Reparation of an Inflamed Air-Liquid Interface Cultured A549 Cells with Nebulized Nanocurcumin. Pharmaceutics 13:9, pages 1331.
Crossref
E. Nozza, S. Valentini, G. Melzi, R. Vecchi & E. Corsini. (2021) Advances on the immunotoxicity of outdoor particulate matter: A focus on physical and chemical properties and respiratory defence mechanisms. Science of The Total Environment 780, pages 146391.
Crossref
Domizia Baldassi, Bettina Gabold & Olivia M. Merkel. (2021) Air−Liquid Interface Cultures of the Healthy and Diseased Human Respiratory Tract: Promises, Challenges, and Future Directions. Advanced NanoBiomed Research 1:6.
Crossref
Matthias Hufnagel, Ronja Neuberger, Johanna Wall, Martin Link, Alexandra Friesen & Andrea Hartwig. (2021) Impact of Differentiated Macrophage-Like Cells on the Transcriptional Toxicity Profile of CuO Nanoparticles in Co-Cultured Lung Epithelial Cells. International Journal of Molecular Sciences 22:9, pages 5044.
Crossref
Denise M. Mitrano, Peter Wick & Bernd Nowack. (2021) Placing nanoplastics in the context of global plastic pollution. Nature Nanotechnology 16:5, pages 491-500.
Crossref
Jee-hyun Hwang, Haengdueng Jeong, Ye-on Jung, Ki Taek Nam & Kyung-Min Lim. (2021) Skin irritation and inhalation toxicity of biocides evaluated with reconstructed human epidermis and airway models. Food and Chemical Toxicology 150, pages 112064.
Crossref
Nahyun Lee, Dae Yong Jang, Do Hyeon Lee, Haengdueng Jeong, Ki Taek Nam, Dal-Woong Choi & Kyung-Min Lim. (2021) Local Toxicity of Biocides after Direct and Aerosol Exposure on the Human Skin Epidermis and Airway Tissue Models. Toxics 9:2, pages 29.
Crossref
Albert Giralt, Anita R Iskandar, Florian Martin, Elisa Moschini, Tomasso Serchi, Athanasios Kondylis, Diego Marescotti, Patrice Leroy, Laura Ortega-Torres, Shoaib Majeed, Celine Merg, Keyur Trivedi, Emmanuel Guedj, Stefan Frentzel, Nikolai V. Ivanov, Manuel C Peitsch, Arno C Gutleb & Julia Hoeng. (2021) Comparison of the biological impact of aerosol of e-vapor device with MESH® technology and cigarette smoke on human bronchial and alveolar cultures. Toxicology Letters 337, pages 98-110.
Crossref
Xiaoliang Liao, Ting Zou, Min Chen, Yuanyuan Song, Chun Yang, Bojun Qiu, Zhi-Feng Chen, Suk Ying Tsang, Zenghua Qi & Zongwei Cai. (2021) Contamination profiles and health impact of benzothiazole and its derivatives in PM2.5 in typical Chinese cities. Science of The Total Environment 755, pages 142617.
Crossref
Sagarika Bhattacharjee & Harmanpreet Singh. 2021. Applications of 3D printing in Biomedical Engineering. Applications of 3D printing in Biomedical Engineering 21 43 .
Kyoung Ah Min & Gus R. Rosania. 2021. Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery. Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery 3 39 .
Guanghe Wang, Xiaofeng Zhang, Xinyan Liu & Jing Zheng. (2020) Co-culture of human alveolar epithelial (A549) and macrophage (THP-1) cells to study the potential toxicity of ambient PM2.5: a comparison of growth under ALI and submerged conditions. Toxicology Research 9:5, pages 636-651.
Crossref
Charlotte De Rudder, Cristina Garcia-Tímermans, Ilke De Boeck, Sarah Lebeer, Tom Van de Wiele & Marta Calatayud Arroyo. (2020) Lacticaseibacillus casei AMBR2 modulates the epithelial barrier function and immune response in a donor-derived nasal microbiota manner. Scientific Reports 10:1.
Crossref
Zenghua Qi, Yanhao Zhang, Zhi-Feng Chen, Chun Yang, Yuanyuan Song, Xiaoliang Liao, Weiquan Li, Suk Ying Tsang, Guoguang Liu & Zongwei Cai. (2020) Chemical identity and cardiovascular toxicity of hydrophobic organic components in PM2.5. Ecotoxicology and Environmental Safety 201, pages 110827.
Crossref
Marina Figliuzzi, Matteo Tironi, Lorena Longaretti, Alessandro Mancini, Federico Teoldi, Fabio Sangalli & Andrea Remuzzi. (2020) Copper-dependent biological effects of particulate matter produced by brake systems on lung alveolar cells. Archives of Toxicology 94:9, pages 2965-2979.
Crossref
Hana Barosova, Bedia Begum Karakocak, Dedy Septiadi, Alke Petri-Fink, Vicki Stone & Barbara Rothen-Rutishauser. (2020) An In Vitro Lung System to Assess the Proinflammatory Hazard of Carbon Nanotube Aerosols. International Journal of Molecular Sciences 21:15, pages 5335.
Crossref
Angela A. M. Kämpfer, Mathias Busch & Roel P. F. Schins. (2020) Advanced In Vitro Testing Strategies and Models of the Intestine for Nanosafety Research . Chemical Research in Toxicology 33:5, pages 1163-1178.
Crossref
Jeongju Kim, Jeong Jae Kim & Sang Joon Lee. (2020) Efficient removal of indoor particulate matter using water microdroplets generated by a MHz-frequency ultrasonic atomizer. Building and Environment 175, pages 106797.
Crossref
Michal Vojtisek-Lom, Martin Pechout, David Macoun, Rajesh Rameswaran, Kalpita Kumar Praharaj, Tereza Cervena, Jan Topinka & Pavel Rossner. (2019) Assessing Exhaust Toxicity with Biological Detector: Configuration of Portable Air-Liquid Interface Human Lung Cell Model Exposure System, Sampling Train and Test Conditions. SAE International Journal of Advances and Current Practices in Mobility 2:2, pages 520-534.
Crossref
Hana Barosova, Anna G. Maione, Dedy Septiadi, Monita SharmaLaetitia Haeni, Sandor Balog, Olivia O’Connell, George R. Jackson, David BrownAmy J. ClippingerPatrick Hayden, Alke Petri-Fink, Vicki StoneBarbara Rothen-Rutishauser. (2020) Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multiwalled Carbon Nanotubes. ACS Nano 14:4, pages 3941-3956.
Crossref
Jose Zavala, Anastasia N. Freedman, John T. Szilagyi, Ilona Jaspers, John F. Wambaugh, Mark Higuchi & Julia E. Rager. (2020) New Approach Methods to Evaluate Health Risks of Air Pollutants: Critical Design Considerations for In Vitro Exposure Testing. International Journal of Environmental Research and Public Health 17:6, pages 2124.
Crossref
Joana Magalhães, Marina Pinheiro, Barbara Drasler, Dedy Septiadi, Alke Petri-Fink, Susana G Santos, Barbara Rothen-Rutishauser & Salette Reis. (2020) Lipid nanoparticles biocompatibility and cellular uptake in a 3D human lung model. Nanomedicine 15:3, pages 259-271.
Crossref
Pranita K. Kabadi, April L. Rodd, Alysha E. Simmons, Norma J. Messier, Robert H. Hurt & Agnes B. Kane. (2019) A novel human 3D lung microtissue model for nanoparticle-induced cell-matrix alterations. Particle and Fibre Toxicology 16:1.
Crossref
F. Oesch, E. Fabian & Robert Landsiedel. (2019) Xenobiotica-metabolizing enzymes in the lung of experimental animals, man and in human lung models. Archives of Toxicology 93:12, pages 3419-3489.
Crossref
Yi Wang, Anping Peng, Zeyou Chen, Xin Jin & Cheng Gu. (2019) Transformation of gaseous 2-bromophenol on clay mineral dust and the potential health effect. Environmental Pollution 250, pages 686-694.
Crossref
Tereza Cervena, Kristyna Vrbova, Andrea Rossnerova, Jan Topinka & Pavel RossnerJrJr. (2019) Short-term and Long-term Exposure of the MucilAir™ Model to Polycyclic Aromatic Hydrocarbons. Alternatives to Laboratory Animals 47:1, pages 9-18.
Crossref
Roman Lehner, Christoph Weder, Alke Petri-Fink & Barbara Rothen-Rutishauser. (2019) Emergence of Nanoplastic in the Environment and Possible Impact on Human Health. Environmental Science & Technology 53:4, pages 1748-1765.
Crossref
Guanghe Wang, Xiaofeng Zhang, Xinyan Liu, Jing Zheng, Renjie Chen & Haidong Kan. (2019) Ambient fine particulate matter induce toxicity in lung epithelial-endothelial co-culture models. Toxicology Letters 301, pages 133-145.
Crossref
Christoph Bisig, Carola Voss, Alke Petri-Fink & Barbara Rothen-Rutishauser. (2019) The crux of positive controls - Pro-inflammatory responses in lung cell models. Toxicology in Vitro 54, pages 189-193.
Crossref
Ali Kermanizadeh, David M. Brown & Peter Møller. 2019. Nanomaterials for Food Applications. Nanomaterials for Food Applications 355 380 .
Thomas Loret, Françoise Rogerieux, Bénédicte Trouiller, Anne Braun, Christophe Egles & Ghislaine Lacroix. (2018) Predicting the in vivo pulmonary toxicity induced by acute exposure to poorly soluble nanomaterials by using advanced in vitro methods. Particle and Fibre Toxicology 15:1.
Crossref
Daniel Cozens, Erin Sutherland, Francesco Marchesi, Geraldine Taylor, Catherine C. Berry & Robert L. Davies. (2018) Temporal differentiation of bovine airway epithelial cells grown at an air-liquid interface. Scientific Reports 8:1.
Crossref
Swapna Upadhyay & Lena Palmberg. (2018) Air-Liquid Interface: Relevant In Vitro Models for Investigating Air Pollutant-Induced Pulmonary Toxicity. Toxicological Sciences 164:1, pages 21-30.
Crossref
Hana Barosova, Savvina Chortarea, Pavlina Peikertova, Martin J. D. Clift, Alke Petri-Fink, Jana Kukutschova & Barbara Rothen-Rutishauser. (2018) Biological response of an in vitro human 3D lung cell model exposed to brake wear debris varies based on brake pad formulation. Archives of Toxicology 92:7, pages 2339-2351.
Crossref
Christie M. SayesMadhuri Singal. (2018) Optimizing a Test Bed System to Assess Human Respiratory Safety After Exposure to Chemical and Particle Aerosolization. Applied In Vitro Toxicology 4:2, pages 193-201.
Crossref
Patrick D. McMullen, Melvin E. Andersen, Brian Cholewa, Harvey J. ClewellIIIIII, Katherine M. Dunnick, Jessica K. Hartman, Kamel Mansouri, Melyssa S. Minto, Chantel I. Nicolas, Martin B. Phillips, Scott Slattery, Miyoung Yoon & Rebecca A. Clewell. (2018) Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays. Toxicology in Vitro 48, pages 310-317.
Crossref
Dania Movia & Adriele Prina-Mello. 2018. Unraveling the Safety Profile of Nanoscale Particles and Materials - From Biomedical to Environmental Applications. Unraveling the Safety Profile of Nanoscale Particles and Materials - From Biomedical to Environmental Applications.
Kinga Balogh Sivars, Ulf Sivars, Ellinor Hornberg, Hui Zhang, Lena Brändén, Rosy Bonfante, Song Huang, Samuel Constant, Ian Robinson, Catherine J Betts & Per M Åberg. (2018) A 3D Human Airway Model Enables Prediction of Respiratory Toxicity of Inhaled Drugs In Vitro. Toxicological Sciences 162:1, pages 301-308.
Crossref
Aline Chary, Jennifer Hennen, Sebastian G. Klein, Tommaso Serchi, Arno C. Gutleb & Brunhilde Blömeke. (2017) Respiratory sensitization: toxicological point of view on the available assays. Archives of Toxicology 92:2, pages 803-822.
Crossref
Tong He, Jimin Long, Juan Li, Liangliang Liu & Yi Cao. (2017) Toxicity of ZnO nanoparticles (NPs) to A549 cells and A549 epithelium in vitro: Interactions with dipalmitoyl phosphatidylcholine (DPPC). Environmental Toxicology and Pharmacology 56, pages 233-240.
Crossref
Yu Shang, Qian Zhou, Tiantian Wang, Yuting Jiang, Yufang Zhong, Guangren Qian, Tong Zhu, Xinghua Qiu & Jing An. (2017) Airborne nitro-PAHs induce Nrf2/ARE defense system against oxidative stress and promote inflammatory process by activating PI3K/Akt pathway in A549 cells. Toxicology in Vitro 44, pages 66-73.
Crossref
Dania Movia, Luisana Di Cristo, Roaa Alnemari, Joseph E. McCarthy, Hanane Moustaoui, Marc Lamy de la Chapelle, Jolanda Spadavecchia, Yuri Volkov & Adriele Prina-Mello. (2017) The curious case of how mimicking physiological complexity in in vitro models of the human respiratory system influences the inflammatory responses. A preliminary study focused on gold nanoparticles. Journal of Interdisciplinary Nanomedicine 2:2, pages 110-130.
Crossref
K. Kaviyarasu, N. Geetha, K. Kanimozhi, C. Maria Magdalane, S. Sivaranjani, A. Ayeshamariam, J. Kennedy & M. Maaza. (2017) In vitro cytotoxicity effect and antibacterial performance of human lung epithelial cells A549 activity of Zinc oxide doped TiO 2 nanocrystals: Investigation of bio-medical application by chemical method. Materials Science and Engineering: C 74, pages 325-333.
Crossref
Martin J. D. Clift, Kleanthis Fytianos, Dimitri Vanhecke, Sandra Hočevar, Alke Petri-Fink & Barbara Rothen-Rutishauser. (2017) A novel technique to determine the cell type specific response within an in vitro co-culture model via multi-colour flow cytometry. Scientific Reports 7:1.
Crossref
Andreas C. Hocke, Norbert Suttorp & Stefan Hippenstiel. (2016) Human lung ex vivo infection models. Cell and Tissue Research 367:3, pages 511-524.
Crossref
Stephen J. Evans, Martin J. D. Clift, Neenu Singh, Jefferson de Oliveira Mallia, Michael Burgum, John W. Wills, Thomas S. Wilkinson, Gareth J. S. Jenkins & Shareen H. Doak. (2017) Critical review of the current and future challenges associated with advanced in vitro systems towards the study of nanoparticle (secondary) genotoxicity . Mutagenesis 32:1, pages 233-241.
Crossref
M. Maskos & R.H. Stauber. 2017. Comprehensive Biomaterials II. Comprehensive Biomaterials II 467 481 .
Dorleta Jimenez de Aberasturi, Ana B. Serrano-Montes, Judith Langer, Malou Henriksen-Lacey, Wolfgang J. Parak & Luis M. Liz-Marzán. (2016) Surface Enhanced Raman Scattering Encoded Gold Nanostars for Multiplexed Cell Discrimination. Chemistry of Materials 28:18, pages 6779-6790.
Crossref
Katerina Malachova, Jana Kukutschova, Zuzana Rybkova, Hana Sezimova, Daniela Placha, Kristina Cabanova & Peter Filip. (2016) Toxicity and mutagenicity of low-metallic automotive brake pad materials. Ecotoxicology and Environmental Safety 131, pages 37-44.
Crossref
Monita Sharma, Jake Nikota, Sabina Halappanavar, Vincent Castranova, Barbara Rothen-Rutishauser & Amy J. Clippinger. (2016) Predicting pulmonary fibrosis in humans after exposure to multi-walled carbon nanotubes (MWCNTs). Archives of Toxicology 90:7, pages 1605-1622.
Crossref
Sandro Steiner, Christoph Bisig, Alke Petri-Fink & Barbara Rothen-Rutishauser. (2016) Diesel exhaust: current knowledge of adverse effects and underlying cellular mechanisms. Archives of Toxicology 90:7, pages 1541-1553.
Crossref
Amy J. Clippinger, Arti Ahluwalia, David Allen, James C. Bonner, Warren Casey, Vincent Castranova, Raymond M. David, Sabina Halappanavar, Jon A. Hotchkiss, Annie M. Jarabek, Monika Maier, William Polk, Barbara Rothen-Rutishauser, Christie M. Sayes, Phil Sayre, Monita Sharma & Vicki Stone. (2016) Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials. Archives of Toxicology 90:7, pages 1769-1783.
Crossref
Chor Yong Tay, Madaswamy S. Muthu, Sing Ling Chia, Kim Truc Nguyen, Si-Shen Feng & David Tai Leong. (2016) Reality Check for Nanomaterial-Mediated Therapy with 3D Biomimetic Culture Systems. Advanced Functional Materials 26:23, pages 4046-4065.
Crossref
Ingeborg M. KooterMariska Gröllers-MulderijMaaike SteenhofEvert DuistermaatFrederique A.A. van AckerYvonne C.M. StaalPeter C. TrompEric SchoenC. Frieke KuperEugene van Someren. (2016) Cellular Effects in an In Vitro Human 3D Cellular Airway Model and A549/BEAS-2B In Vitro Cell Cultures Following Air Exposure to Cerium Oxide Particles at an Air–Liquid Interface . Applied In Vitro Toxicology 2:1, pages 56-66.
Crossref
Dick Papazian, Peter A. Würtzen & Soren W.K. Hansen. (2016) Polarized Airway Epithelial Models for Immunological Co-Culture Studies. International Archives of Allergy and Immunology 170:1, pages 1-21.
Crossref
Zhonghui Zhu, Yan Wang, Di Liang, Gengxia Yang, Li Chen, Piye Niu & Lin Tian. (2016) Sodium tanshinone IIA sulfonate suppresses pulmonary fibroblast proliferation and activation induced by silica: role of the Nrf2/Trx pathway. Toxicology Research 5:1, pages 116-125.
Crossref
Dick Papazian, Tashi Chhoden, Maria Arge, Thomas Vorup-Jensen, Claus H. Nielsen, Kaare Lund, Peter A. Würtzen & Soren Hansen. (2015) Effect of Polarization on Airway Epithelial Conditioning of Monocyte-Derived Dendritic Cells. American Journal of Respiratory Cell and Molecular Biology 53:3, pages 368-377.
Crossref
C. FANIZZA, S. CASCIARDI, F. INCORONATO, D. CAVALLO, C.L. URSINI, A. CIERVO, R. MAIELLO, A.M. FRESEGNA, A.M. MARCELLONI, D. LEGA, A. ALVINO & S. BAIGUERA. (2015) Human epithelial cells exposed to functionalized multiwalled carbon nanotubes: interactions and cell surface modifications. Journal of Microscopy 259:3, pages 173-184.
Crossref
Esther MeloJennifer Y. KasperRonald E. UngerRamon FarréCharles James Kirkpatrick. (2015) Development of a Bronchial Wall Model: Triple Culture on a Decellularized Porcine Trachea. Tissue Engineering Part C: Methods 21:9, pages 909-921.
Crossref
Christoph Bisig, Sandro Steiner, Pierre Comte, Jan Czerwinski, Andreas Mayer, Alke Petri-Fink & Barbara Rothen-Rutishauser. (2015) Biological Effects in Lung Cells In Vitro of Exhaust Aerosols from a Gasoline Passenger Car With and Without Particle Filter. Emission Control Science and Technology 1:3, pages 237-246.
Crossref
Brandi N. Snyder-Talkington, Chunlin Dong, Xiangyi Zhao, Julian Dymacek, Dale W. Porter, Michael G. Wolfarth, Vincent Castranova, Yong Qian & Nancy L. Guo. (2015) Multi-walled carbon nanotube-induced gene expression in vitro: Concordance with in vivo studies. Toxicology 328, pages 66-74.
Crossref
Lenke Horváth, Yuki Umehara, Corinne Jud, Fabian Blank, Alke Petri-Fink & Barbara Rothen-Rutishauser. (2015) Engineering an in vitro air-blood barrier by 3D bioprinting. Scientific Reports 5:1.
Crossref
Carole MathisStephan GebelCarine PoussinVincenzo BelcastroAlain SewerDirk WeisenseeArnd HengstermannSam AnsariSandra WagnerManuel C. PeitschJulia Hoeng. (2015) A Systems Biology Approach Reveals the Dose- and Time-Dependent Effect of Primary Human Airway Epithelium Tissue Culture after Exposure to Cigarette Smoke in Vitro. Bioinformatics and Biology Insights 9, pages BBI.S19908.
Crossref
Peter Wick, Stefanie Grafmueller, Alke Petri-Fink & Barbara Rothen-Rutishauser. (2014) Advanced human in vitro models to assess metal oxide nanoparticle-cell interactions . MRS Bulletin 39:11, pages 984-989.
Crossref
Caterina Fede, Caterina Millino, Beniamina Pacchioni, Barbara Celegato, Chiara Compagnin, Paolo Martini, Francesco Selvestrel, Fabrizio Mancin, Lucia Celotti, Gerolamo Lanfranchi, Maddalena Mognato & Stefano Cagnin. (2014) Altered Gene Transcription in Human Cells Treated with Ludox® Silica Nanoparticles. International Journal of Environmental Research and Public Health 11:9, pages 8867-8890.
Crossref
Peishan Ding, Huimei Wu, Lei Fang, Ming Wu & Rongyu Liu. (2014) Transmigration and Phagocytosis of Macrophages in an Airway Infection Model Using Four-dimensional Techniques. American Journal of Respiratory Cell and Molecular Biology 51:1, pages 1-10.
Crossref
Ben Forbes, Raegan O'Lone, Philippa Pribul Allen, Anthony Cahn, Chris Clarke, Mark Collinge, Lea Ann Dailey, Louise E. Donnelly, Joseph Dybowski, David Hassall, Deon Hildebrand, Rhys Jones, Joanne Kilgour, Jan Klapwijk, Curtis C. Maier, Tim McGovern, Kristen Nikula, Joel D. Parry, Matthew D. Reed, Ian Robinson, Lindsay Tomlinson & Alison Wolfreys. (2014) Challenges for inhaled drug discovery and development: Induced alveolar macrophage responses. Advanced Drug Delivery Reviews 71, pages 15-33.
Crossref
Christoph Giese & Uwe Marx. (2014) Human immunity in vitro — Solving immunogenicity and more. Advanced Drug Delivery Reviews 69-70, pages 103-122.
Crossref
Kelechi Ugonna, Colin D. Bingle, Karen Plant, Kirsty Wilson & Mark L. Everard. (2014) Macrophages Are Required for Dendritic Cell Uptake of Respiratory Syncytial Virus from an Infected Epithelium. PLoS ONE 9:3, pages e91855.
Crossref
Eleonore Fröhlich & Sharareh Salar-Behzadi. (2014) Toxicological Assessment of Inhaled Nanoparticles: Role of in Vivo, ex Vivo, in Vitro, and in Silico Studies. International Journal of Molecular Sciences 15:3, pages 4795-4822.
Crossref
Dania Movia, Valerie Gerard, Ciaran Manus Maguire, Namrata Jain, Alan P. Bell, Valeria Nicolosi, Tiina O'Neill, Dimitri Scholz, Yurii Gun'ko, Yuri Volkov & Adriele Prina-Mello. (2014) A safe-by-design approach to the development of gold nanoboxes as carriers for internalization into cancer cells. Biomaterials 35:9, pages 2543-2557.
Crossref
Martin J. D. Clift, Carola Endes, Dimitri Vanhecke, Peter Wick, Peter Gehr, Roel P. F. Schins, Alke Petri-Fink & Barbara Rothen-Rutishauser. (2014) A Comparative Study of Different In Vitro Lung Cell Culture Systems to Assess the Most Beneficial Tool for Screening the Potential Adverse Effects of Carbon Nanotubes. Toxicological Sciences 137:1, pages 55-64.
Crossref
Samir Dekali, Christelle Gamez, Thierry Kortulewski, Kelly Blazy, Patrice Rat & Ghislaine Lacroix. (2014) Assessment of an in vitro model of pulmonary barrier to study the translocation of nanoparticles. Toxicology Reports 1, pages 157-171.
Crossref
Brandi N Snyder-Talkington, Diane Schwegler-Berry, Vincent Castranova, Yong Qian & Nancy L Guo. (2013) Multi-walled carbon nanotubes induce human microvascular endothelial cellular effects in an alveolar-capillary co-culture with small airway epithelial cells. Particle and Fibre Toxicology 10:1.
Crossref
Fabian Herzog, Martin JD Clift, Flavio Piccapietra, Renata Behra, Otmar Schmid, Alke Petri-Fink & Barbara Rothen-Rutishauser. (2013) Exposure of silver-nanoparticles and silver-ions to lung cells in vitro at the air-liquid interface. Particle and Fibre Toxicology 10:1.
Crossref
Simon Heuking, Barbara Rothen-Rutishauser, David Olivier Raemy, Peter Gehr & Gerrit Borchard. (2013) Fate of TLR-1/TLR-2 agonist functionalised pDNA nanoparticles upon deposition at the human bronchial epithelium in vitro. Journal of Nanobiotechnology 11:1.
Crossref
R Zellner, J Blechinger, C Bräuchle, I Hilger, A Janshoff, J Lademann, V Mailänder, M Meinke, G Nienhaus, A Patzelt, F Rancan, B Rothen-Rutishauser, R Stauber, A Torrano, L Treuel & A Vogt. 2013. Safety Aspects of Engineered Nanomaterials. Safety Aspects of Engineered Nanomaterials 157 218 .
Xiaobei Deng, Wei Rui, Fang Zhang & Wenjun Ding. (2013) PM2.5 induces Nrf2-mediated defense mechanisms against oxidative stress by activating PIK3/AKT signaling pathway in human lung alveolar epithelial A549 cells. Cell Biology and Toxicology 29:3, pages 143-157.
Crossref
C Endes, S Müller, O Schmid, D Vanhecke, E J Foster, A Petri-Fink, B Rothen-Rutishauser, C Weder & M J D Clift. (2013) Risk assessment of released cellulose nanocrystals – mimicking inhalatory exposure. Journal of Physics: Conference Series 429, pages 012008.
Crossref
Loretta MüllerLuisa E. BrightonIlona Jaspers. (2013) Ozone exposed epithelial cells modify cocultured natural killer cells. American Journal of Physiology-Lung Cellular and Molecular Physiology 304:5, pages L332-L341.
Crossref
Porntipa Chairuangkitti, Somsong Lawanprasert, Sittiruk Roytrakul, Sasitorn Aueviriyavit, Duangkamol Phummiratch, Kornphimol Kulthong, Pithi Chanvorachote & Rawiwan Maniratanachote. (2013) Silver nanoparticles induce toxicity in A549 cells via ROS-dependent and ROS-independent pathways. Toxicology in Vitro 27:1, pages 330-338.
Crossref
Craig A. Poland & Martin J. D. Clift. 2013. Bio‐Nanotechnology. Bio‐Nanotechnology 749 775 .
Michaela Aufderheide, Beat Halter, Niklas Möhle & Dieter Hochrainer. (2013) The CULTEX RFS: A Comprehensive Technical Approach for the In Vitro Exposure of Airway Epithelial Cells to the Particulate Matter at the Air-Liquid Interface . BioMed Research International 2013, pages 1-15.
Crossref
Abderrahim Nemmar, Jørn A. Holme, Irma Rosas, Per E. Schwarze & Ernesto Alfaro-Moreno. (2013) Recent Advances in Particulate Matter and Nanoparticle Toxicology: A Review of the In Vivo and In Vitro Studies . BioMed Research International 2013, pages 1-22.
Crossref
Martin J. D. Clift & Barbara Rothen-Rutishauser. 2013. Oxidative Stress and Nanotechnology. Oxidative Stress and Nanotechnology 115 133 .
Barbara Rothen-Rutishauser, Martin J.D. Clift, Corinne Jud, Alke Fink & Peter Wick. (2012) Human epithelial cells in vitro – Are they an advantageous tool to help understand the nanomaterial-biological barrier interaction?. EURO-NanoTox-Letters 4:1, pages 1-19.
Crossref
Michael Gasser, Peter Wick, Martin JD Clift, Fabian Blank, Liliane Diener, Bing Yan, Peter Gehr, Harald F Krug & Barbara Rothen-Rutishauser. (2012) Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro. Particle and Fibre Toxicology 9:1.
Crossref
Sasitorn Aueviriyavit, Duangkamol Phummiratch, Kornphimol Kulthong & Rawiwan Maniratanachote. (2012) Titanium Dioxide Nanoparticles-Mediated In Vitro Cytotoxicity Does Not Induce Hsp70 and Grp78 Expression in Human Bronchial Epithelial A549 Cells. Biological Trace Element Research 149:1, pages 123-132.
Crossref
Julian Kirch†Christian A. Ruge, Craig Schneider†Justin Hanes & Claus-Michael Lehr*. 2012. Nanostructured Biomaterials for Overcoming Biological Barriers. Nanostructured Biomaterials for Overcoming Biological Barriers 239 272 .
Christine Poon, Mei Zhang, Andrew Ruys, Angela Hong, Christelle Catuogno & Philip Boughton. (2012) A Novel Dynamic 3-Dimensional Construct for Respiratory Tissue Engineering. Journal of Biomimetics, Biomaterials and Tissue Engineering 14, pages 31-42.
Crossref
Carl Persson & Lena Uller. (2012) Resolution of leucocyte‐mediated mucosal diseases. A novel in vivo paradigm for drug development . British Journal of Pharmacology 165:7, pages 2100-2109.
Crossref
Di Wu, Elena S. Pak, Christopher J. Wingard & Alexander K. Murashov. (2012) Multi-walled carbon nanotubes inhibit regenerative axon growth of dorsal root ganglia neurons of mice. Neuroscience Letters 507:1, pages 72-77.
Crossref
Pilar Rivera_Gil, Martin J. D. Clift, Barbara Rothen Rutishauser & Wolfgang J. Parak. 2012. Nanotoxicity. Nanotoxicity 33 56 .
Sebastian G. Klein, Jenny Hennen, Tommaso Serchi, Brunhilde Blömeke & Arno C. Gutleb. (2011) Potential of coculture in vitro models to study inflammatory and sensitizing effects of particles on the lung. Toxicology in Vitro 25:8, pages 1516-1534.
Crossref
Martin J. D. Clift, E. Johan Foster, Dimitri Vanhecke, Daniel Studer, Peter Wick, Peter Gehr, Barbara Rothen-Rutishauser & Christoph Weder. (2011) Investigating the Interaction of Cellulose Nanofibers Derived from Cotton with a Sophisticated 3D Human Lung Cell Coculture. Biomacromolecules 12:10, pages 3666-3673.
Crossref
Hanns-Rudolf Paur, Flemming R. Cassee, Justin Teeguarden, Heinz Fissan, Silvia Diabate, Michaela Aufderheide, Wolfgang G. Kreyling, Otto Hänninen, Gerhard Kasper, Michael Riediker, Barbara Rothen-Rutishauser & Otmar Schmid. (2011) In-vitro cell exposure studies for the assessment of nanoparticle toxicity in the lung—A dialog between aerosol science and biology. Journal of Aerosol Science 42:10, pages 668-692.
Crossref
Venkataramana K. Sidhaye, Eric Chau, Patrick N. Breysse & Landon S. King. (2011) Septin-2 Mediates Airway Epithelial Barrier Function in Physiologic and Pathologic Conditions. American Journal of Respiratory Cell and Molecular Biology 45:1, pages 120-126.
Crossref
Martin J. D. Clift, Peter Gehr & Barbara Rothen-Rutishauser. (2010) Nanotoxicology: a perspective and discussion of whether or not in vitro testing is a valid alternative. Archives of Toxicology 85:7, pages 723-731.
Crossref
Peter Gehr, Martin J.D Clift, Christina Brandenberger, Andrea Lehmann, Fabian Herzog & Barbara Rothen‐Rutishauser. 2011. Comprehensive Physiology. Comprehensive Physiology 1159 1174 .
Regina Scherließ. (2011) The MTT assay as tool to evaluate and compare excipient toxicity in vitro on respiratory epithelial cells. International Journal of Pharmaceutics 411:1-2, pages 98-105.
Crossref
David O. Raemy, Ludwig K. Limbach, Barbara Rothen-Rutishauser, Robert N. Grass, Peter Gehr, Karin Birbaum, Christina Brandenberger, Detlef Günther & Wendelin J. Stark. (2011) Cerium oxide nanoparticle uptake kinetics from the gas-phase into lung cells in vitro is transport limited. European Journal of Pharmaceutics and Biopharmaceutics 77:3, pages 368-375.
Crossref
Andrea D. Lehmann, Nicole Daum, Michael Bur, Claus-Michael Lehr, Peter Gehr & Barbara M. Rothen-Rutishauser. (2011) An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier. European Journal of Pharmaceutics and Biopharmaceutics 77:3, pages 398-406.
Crossref
Harald F. Krug & Peter Wick. (2011) Nanotoxicology: An Interdisciplinary Challenge. Angewandte Chemie International Edition 50:6, pages 1260-1278.
Crossref
Harald F. Krug & Peter Wick. (2011) Nanotoxikologie – eine interdisziplinäre Herausforderung. Angewandte Chemie 123:6, pages 1294-1314.
Crossref
Tina Thurnherr, Christina Brandenberger, Kathrin Fischer, Liliane Diener, Pius Manser, Xenia Maeder-Althaus, Jean-Pierre Kaiser, Harald F. Krug, Barbara Rothen-Rutishauser & Peter Wick. (2011) A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro. Toxicology Letters 200:3, pages 176-186.
Crossref
Fabian Blank, Marc Wehrli, Andrea Lehmann, Oliver Baum, Peter Gehr, Christophe von Garnier & Barbara M. Rothen-Rutishauser. (2011) Macrophages and dendritic cells express tight junction proteins and exchange particles in an in vitro model of the human airway wall. Immunobiology 216:1-2, pages 86-95.
Crossref
M. Maskos & R.H. Stauber. 2011. Comprehensive Biomaterials. Comprehensive Biomaterials 329 339 .
Robert N. Grass, Ludwig K. Limbach, Evagelos K. Athanassiou & Wendelin J. Stark. (2010) Exposure of aerosols and nanoparticle dispersions to in vitro cell cultures: A review on the dose relevance of size, mass, surface and concentration. Journal of Aerosol Science 41:12, pages 1123-1142.
Crossref
P. Berntsen, C. Y. Park, B. Rothen-Rutishauser, A. Tsuda, T. M. Sager, R. M. Molina, T. C. Donaghey, A. M. Alencar, D. I. Kasahara, T. Ericsson, E. J. Millet, J. Swenson, D. J. Tschumperlin, J. P. Butler, J. D. Brain, J. J. Fredberg, P. Gehr & E. H. Zhou. (2010) Biomechanical effects of environmental and engineered particles on human airway smooth muscle cells. Journal of The Royal Society Interface 7:suppl_3.
Crossref
Loretta MüllerPierre ComteJan CzerwinskiMarkus KasperAndreas C. R. MayerPeter GehrHeinz BurtscherJean-Paul MorinAthanasios KonstandopoulosBarbara Rothen-Rutishauser. (2010) New Exposure System To Evaluate the Toxicity of (Scooter) Exhaust Emissions in Lung Cells in Vitro. Environmental Science & Technology 44:7, pages 2632-2638.
Crossref
Andrea D. Lehmann, Wolfgang J. Parak, Feng Zhang, Zulqurnain Ali, Carlheinz Röcker, G. Ulrich Nienhaus, Peter Gehr & Barbara Rothen-Rutishauser. (2010) Fluorescent-Magnetic Hybrid Nanoparticles Induce a Dose-Dependent Increase in Proinflammatory Response in Lung Cells in vitro Correlated with Intracellular Localization. Small 6:6, pages 753-762.
Crossref
Loretta Müller, Michael Riediker, Peter Wick, Martin Mohr, Peter Gehr & Barbara Rothen-Rutishauser. (2009) Oxidative stress and inflammation response after nanoparticle exposure: differences between human lung cell monocultures and an advanced three-dimensional model of the human epithelial airways. Journal of The Royal Society Interface 7:suppl_1.
Crossref
Umme S. Akhtar, Jeremy A. Scott, Amanda Chu & Greg J. Evans. 2011. Urban Airborne Particulate Matter. Urban Airborne Particulate Matter 427 449 .
Christina Brandenberger, Barbara Rothen-Rutishauser, Fabian Blank, Peter Gehr & Christian Mühlfeld. (2009) Particles induce apical plasma membrane enlargement in epithelial lung cell line depending on particle surface area dose. Respiratory Research 10:1.
Crossref
Martin J. D. Clift, Fabian Blank, Peter Gehr & Barbara Rothen‐Rutishauser. 2009. General, Applied and Systems Toxicology. General, Applied and Systems Toxicology.
Barbara Rothen-Rutishauser, Martin Clift, Christina Brandenberger, Andrea Lehmann, Loretta Müller, David Raemy & Peter Gehr. (2009) An in vitro model of the human epithelial airway barrier to study the toxicity of nanoparticles. Toxicology Letters 189, pages S35-S36.
Crossref
Fabian Blank, Peter Gehr & Barbara Rothen‐Rutishauser. 2009. Nanotoxicity. Nanotoxicity 379 395 .
Margriet VDZ Park, Daniëlle PK LankveldHenk van Loveren & Wim H de Jong. (2009) The status of in vitro toxicity studies in the risk assessment of nanomaterials . Nanomedicine 4:6, pages 669-685.
Crossref
Barbara Rothen-Rutishauser, Robert N. Grass, Fabian Blank, Ludwig K. Limbach, Christian Mühlfeld, Christina Brandenberger, David O. Raemy, Peter Gehr & Wendelin J. Stark. (2009) Direct Combination of Nanoparticle Fabrication and Exposure to Lung Cell Cultures in a Closed Setup as a Method To Simulate Accidental Nanoparticle Exposure of Humans. Environmental Science & Technology 43:7, pages 2634-2640.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.