Advanced search
Publication Cover
Expert Opinion on Drug Discovery Volume 1, 2006 - Issue 7
Submit an article Journal homepage
154
Views
9
CrossRef citations to date
0
Altmetric
Reviews

Advances in predicting CYP-mediated drug interactions in the drug discovery setting

Jan L Wahlstrom Senior Scientist, Amgen Inc., Pharmacokinetics and Drug Metabolism, 1201 Amgen Court West, Seattle, WA 98119-3105, USA
,
Dan A Rock Senior Scientist, Amgen Inc., Pharmacokinetics and Drug Metabolism, 1201 Amgen Court West, Seattle, WA 98119-3105, USA
,
J Greg Slatter Senior Principal Scientist, Amgen Inc., Pharmacokinetics and Drug Metabolism, 1201 Amgen Court West, Seattle, WA 98119-3105, USA
&
Larry C Wienkers Senior Director of Pharmacokinetics and Drug Metabolism, Amgen Inc., Pharmacokinetics and Drug Metabolism, AW2-D/3392, 1201 Amgen Court West, Seattle, WA 98119-3105, USA. [email protected]
Pages 677-691 | Published online: 07 Dec 2006

Citations (9)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Jianling Wang, Laszlo Urban & Dejan Bojanic. (2007) Maximising use of in vitro ADMET tools to predict in vivo bioavailability and safety. Expert Opinion on Drug Metabolism & Toxicology 3:5, pages 641-665.
Read now

Articles from other publishers (8)

William M. Atkins. (2019) Mechanisms of promiscuity among drug metabolizing enzymes and drug transporters. The FEBS Journal 287:7, pages 1306-1322.
Crossref
Jan Wahlstrom & Larry Wienkers. 2020. Drug Discovery and Evaluation: Methods in Clinical Pharmacology. Drug Discovery and Evaluation: Methods in Clinical Pharmacology 847 866 .
Jan Wahlstrom & Larry Wienkers. 2018. Drug Discovery and Evaluation: Methods in Clinical Pharmacology. Drug Discovery and Evaluation: Methods in Clinical Pharmacology 1 20 .
Katharina Neufeld, Sonja Meyer zu Berstenhorst & Jörg Pietruszka. (2014) Evaluation of coumarin-based fluorogenic P450 BM3 substrates and prospects for competitive inhibition screenings. Analytical Biochemistry 456, pages 70-81.
Crossref
Brooke M. VandenBrink, Robert S. Foti, Dan A. Rock, Larry C. Wienkers & Jan L. Wahlstrom. (2011) Evaluation of CYP2C8 Inhibition In Vitro: Utility of Montelukast as a Selective CYP2C8 Probe Substrate. Drug Metabolism and Disposition 39:9, pages 1546-1554.
Crossref
Robert S. Foti, Dan A. Rock, Larry C. Wienkers & Jan L. Wahlstrom. (2010) Selection of Alternative CYP3A4 Probe Substrates for Clinical Drug Interaction Studies Using In Vitro Data and In Vivo Simulation. Drug Metabolism and Disposition 38:6, pages 981-987.
Crossref
Dil M. Ramanathan & Richard M. Lelacheur. 2008. Mass Spectrometry in Drug Metabolism and Pharmacokinetics. Mass Spectrometry in Drug Metabolism and Pharmacokinetics 1 85 .
Jianling Wang, Laszlo Urban & Dejan Bojanic. (2007) Maximising use of in vitro ADMET tools to predict in vivo bioavailability and safety . Expert Opinion on Drug Metabolism & Toxicology 3:5, pages 641-665.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.