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Expert Opinion on Drug Discovery Volume 7, 2012 - Issue 3
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Gene expression profiling and therapeutic interventions in neurodegenerative diseases: a comprehensive study on potentiality and limits

Federico BenettiLaboratory of Prion Biology, Neurobiology Sector, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, I-34136 Trieste, Italy;Italian Institute of Technology, SISSA Unit, Via Bonomea 265, I-34136 Trieste, Italy
, Ph.D,
Stefano GustincichLaboratory of Neurogenomics, Neurobiology Sector, (SISSA), I-34136 Trieste, Italy
, Ph.D &
Giuseppe LegnameLaboratory of Prion Biology, Neurobiology Sector, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Via Bonomea 265, I-34136 Trieste, Italy;Italian Institute of Technology, SISSA Unit, Via Bonomea 265, I-34136 Trieste, Italy;ELETTRA Laboratory, Sincrotrone Trieste S.C.p.A, I-34149, Basovizza, Trieste, Italy
, D.Phil.
Pages 245-259 | Published online: 13 Feb 2012

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Sangeetha Nagarajan, David Raj Chellappan, Prabu Chinnaswamy & Senthilkumar Thulasingam. (2015) Ferulic acid pretreatment mitigates MPTP-induced motor impairment and histopathological alterations in C57BL/6 mice. Pharmaceutical Biology 53:11, pages 1591-1601.
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Lylyan Fragoso Pimentel, José Eriton Gomes da Cunha, Renato Lírio Morelato, Flávia de Paula & João Ricardo Mendes de Oliveira. (2014) Epidemiological genetics and meta-analysis of a polymorphism at codon 129 of the PRNP gene in Alzheimer’s disease in Brazil. Neurological Research 36:9, pages 775-778.
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Articles from other publishers (13)

Siraj Ahmed, Majid Komeili & Jeongwon Park. (2022) Predictive modelling of Parkinson’s disease progression based on RNA-Sequence with densely connected deep recurrent neural networks. Scientific Reports 12:1.
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Débora Lanznaster, Giulia Dingeo, Rayhanatou Altine Samey, Patrick Emond & Hélène Blasco. (2022) Metabolomics as a Crucial Tool to Develop New Therapeutic Strategies for Neurodegenerative Diseases. Metabolites 12:9, pages 864.
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Silvia Vanni, Arianna Colini Baldeschi, Marco Zattoni & Giuseppe Legname. (2019) Brain aging: A Ianus ‐faced player between health and neurodegeneration . Journal of Neuroscience Research 98:2, pages 299-311.
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Caroline C Real, Janine Doorduin, Paula Kopschina Feltes, David Vállez García, Daniele de Paula Faria, Luiz R Britto & Erik FJ de Vries. (2017) Evaluation of exercise-induced modulation of glial activation and dopaminergic damage in a rat model of Parkinson’s disease using [ 11 C]PBR28 and [ 18 F]FDOPA PET . Journal of Cerebral Blood Flow & Metabolism 39:6, pages 989-1004.
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Raghavendra Prasad, N.P. Guhan Seshadri, R. Periyasamy, Stephanie Miller, Arindam Bit & Kunal Mitra. 2019. Bioelectronics and Medical Devices. Bioelectronics and Medical Devices 145 181 .
Umapathy Dhamodharan, Balashanmugam Ponjayanthi, Dornadula Sireesh, Elango Bhakkiyalakshmi & Kunka Mohanram Ramkumar. (2018) Association of single-nucleotide polymorphisms of the KEAP1 gene with the risk of various human diseases and its functional impact using in silico analysis. Pharmacological Research 137, pages 205-218.
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Silvia Vanni, Marco Zattoni, Fabio Moda, Giorgio Giaccone, Fabrizio Tagliavini, Stéphane Haïk, Jean-Philippe Deslys, Gianluigi Zanusso, James W. Ironside, Margarita Carmona, Isidre Ferrer, Gabor G. Kovacs & Giuseppe Legname. (2018) Hemoglobin mRNA Changes in the Frontal Cortex of Patients with Neurodegenerative Diseases. Frontiers in Neuroscience 12.
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Vahdat Poortahmasebi, Seyed Moayed Alavian, Mohsen Nasiri-Toosi, Mehdi Norouzi, Mostafa Hosseini & Seyed Mohammad Jazayeri. (2017) Transcriptome analysis of peripheral blood mononuclear cells from chronic hepatitis B and hepatocellular carcinoma patients: a network-based attitude. Future Virology 12:12, pages 729-737.
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Saloua Mrabet, Nadia Ben Ali, Afef Achouri, Radhouene Dabbeche, Taoufik Najjar, Slim Haouet & Samir Belal. (2016) Gastrointestinal Dysfunction and Neuropathologic Correlations in Parkinson Disease. Journal of Clinical Gastroenterology 50:9, pages e85-e90.
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Christian Jaeger, Enrico Glaab, Alessandro Michelucci, Tina M. Binz, Sandra Koeglsberger, Pierre Garcia, Jean-Pierre Trezzi, Jenny Ghelfi, Rudi Balling & Manuel Buttini. (2015) The Mouse Brain Metabolome. The American Journal of Pathology 185:6, pages 1699-1712.
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Maura Barbisin, Silvia Vanni, Ann-Christin Schmädicke, Judith Montag, Dirk Motzkus, Lennart Opitz, Gabriela Salinas-Riester & Giuseppe Legname. (2014) Gene expression profiling of brains from bovine spongiform encephalopathy (BSE)-infected cynomolgus macaques. BMC Genomics 15:1.
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Sushil Sharma, Carolyn Seungyoun Moon, Azza Khogali, Ali Haidous, Anthony Chabenne, Comfort Ojo, Miriana Jelebinkov, Yousef Kurdi & Manuchair Ebadi. (2013) Biomarkers in Parkinson’s disease (recent update). Neurochemistry International 63:3, pages 201-229.
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Nicole Schonrock & J?rgen G?tz. (2012) Decoding the non-coding RNAs in Alzheimer?s disease. Cellular and Molecular Life Sciences 69:21, pages 3543-3559.
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