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Novel approaches to glioma drug design and drug screening

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Pages 1135-1151 | Published online: 06 Jun 2013

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Tongxia Zhang, Jie Chai & Lingyi Chi. (2019) Induction Of XLF And 53BP1 Expression Is Associated With Temozolomide Resistance In Glioblastoma Cells. OncoTargets and Therapy 12, pages 10139-10151.
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Komal Anjum, Hongyun Bi, Weiyun Chai, Xiao-Yuan Lian & Zhizhen Zhang. (2018) Antiglioma pseurotin A from marine Bacillus sp. FS8D regulating tumour metabolic enzymes. Natural Product Research 32:11, pages 1353-1356.
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Xuewei Ye, Komal Anjum, Tengfei Song, Wenling Wang, Siran Yu, Haocai Huang, Xiao-Yuan Lian & Zhizhen Zhang. (2016) A new curvularin glycoside and its cytotoxic and antibacterial analogues from marine actinomycete Pseudonocardia sp. HS7. Natural Product Research 30:10, pages 1156-1161.
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Articles from other publishers (27)

Lin Wang, Qinghua Jiang, Siyu Chen, Siyi Wang, Jingyi Lu, Xun Gao, Dongfang Zhang & Xin Jin. (2023) Natural epidithiodiketopiperazine alkaloids as potential anticancer agents: Recent mechanisms of action, structural modification, and synthetic strategies. Bioorganic Chemistry 137, pages 106642.
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Ping Cui, Fanfan Chen, Guoxu Ma, Wenlan Liu, Lei Chen, Sicen Wang, Weiping Li, Zongyang Li & Guodong Huang. (2022) Oxyphyllanene B overcomes temozolomide resistance in glioblastoma: Structure–activity relationship and mitochondria-associated ER membrane dysfunction. Phytomedicine 94, pages 153816.
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Halil I. Ciftci, Mohamed O. Radwan, Belgin Sever, Ahmed K. Hamdy, Safiye Emirdağ, N. Gokce Ulusoy, Ece Sozer, Mustafa Can, Nurettin Yayli, Norie Araki, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita & Mehlika Dilek Altintop. (2021) EGFR-Targeted Pentacyclic Triterpene Analogues for Glioma Therapy. International Journal of Molecular Sciences 22:20, pages 10945.
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Kuo Yong, Sidra Kaleem, Bin Wu & Zhizhen Zhang. (2021) New Antiproliferative Compounds against Glioma Cells from the Marine-Sourced Fungus Penicillium sp. ZZ1750. Marine Drugs 19:9, pages 483.
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Faika Başoğlu, Nuray Ulusoy‐Güzeldemirci, Gülşen Akalın‐Çiftçi, Serap Çetinkaya & Abdulilah Ece. (2021) Novel imidazo[2,1‐ b ]thiazole‐based anticancer agents as potential focal adhesion kinase inhibitors: Synthesis, in silico and in vitro evaluation . Chemical Biology & Drug Design 98:2, pages 270-282.
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Łukasz Uram, Joanna Markowicz, Maria Misiorek, Aleksandra Filipowicz-Rachwał, Stanisław Wołowiec & Elżbieta Wałajtys-Rode. (2020) Celecoxib substituted biotinylated poly(amidoamine) G3 dendrimer as potential treatment for temozolomide resistant glioma therapy and anti-nematode agent. European Journal of Pharmaceutical Sciences 152, pages 105439.
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Wenjun Li, Qian Du, Xiaoli Li, Xiangru Zheng, Feng Lv, Xin Xi, Guili Huang, Jia Yang & Songqing Liu. (2020) Eriodictyol Inhibits Proliferation, Metastasis and Induces Apoptosis of Glioma Cells via PI3K/Akt/NF-κB Signaling Pathway. Frontiers in Pharmacology 11.
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Yifeng Xiong, Rensheng Chen, Lizhen Wang, Shanshan Wang, Yi Tu, Lei Zhu & Chunliang Wang. (2019) Downregulation of miR‑186 promotes the proliferation and drug resistance of glioblastoma cells by targeting Twist1. Molecular Medicine Reports.
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Alexandre Vallée, Yves Lecarpentier, Rémy Guillevin & Jean-Noël Vallée. (2018) Opposite Interplay Between the Canonical WNT/β-Catenin Pathway and PPAR Gamma: A Potential Therapeutic Target in Gliomas. Neuroscience Bulletin 34:3, pages 573-588.
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Mehlika Altıntop, Belgin Sever, Gülşen Akalın Çiftçi & Ahmet Özdemir. (2018) Design, Synthesis, and Evaluation of a New Series of Thiazole-Based Anticancer Agents as Potent Akt Inhibitors. Molecules 23:6, pages 1318.
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Mengxuan Chen, Weiyun Chai, Tengfei Song, Mingzhu Ma, Xiao-Yuan Lian & Zhizhen Zhang. (2018) Anti-glioma Natural Products Downregulating Tumor Glycolytic Enzymes from Marine Actinomycete Streptomyces sp. ZZ406. Scientific Reports 8:1.
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Mariana Lozano-Gonzalez, María Teresa Ramírez-Apan, Antonio Nieto-Camacho, Ruben Alfredo Toscano, Ana Laura Sanchez-Sandoval & Cecilio Alvarez-Toledano. (2018) Anticarcinogenic and metal chelation properties of novel hydroxybenzylidene-1-indanone derivatives in the U-251 glioblastoma cell line. New Journal of Chemistry 42:5, pages 3878-3884.
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Alexandre Vallée, Rémy Guillevin & Jean-Noël Vallée. (2017) Vasculogenesis and angiogenesis initiation under normoxic conditions through Wnt/β-catenin pathway in gliomas. Reviews in the Neurosciences 29:1, pages 71-91.
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Alexandre Vallée, Yves Lecarpentier, Rémy Guillevin & Jean-Noël Vallée. (2017) Thermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma. Frontiers in Physiology 8.
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Lei Chen, Weiyun Chai, Wenling Wang, Tengfei Song, Xiao-Yuan Lian & Zhizhen Zhang. (2017) Cytotoxic Bagremycins from Mangrove-Derived Streptomyces sp. Q22 . Journal of Natural Products 80:5, pages 1450-1456.
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Wenling Wang, Tengfei Song, Weiyun Chai, Lu Chen, Lei Chen, Xiao-Yuan Lian & Zhizhen Zhang. (2017) Rare Polyene-polyol Macrolides from Mangrove-derived Streptomyces sp. ZQ4BG. Scientific Reports 7:1.
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Esther P. Jane, Daniel R. Premkumar, Philip A. Sutera, Jonathon M. Cavaleri & Ian F. Pollack. (2017) Survivin inhibitor YM155 induces mitochondrial dysfunction, autophagy, DNA damage and apoptosis in Bcl-xL silenced glioma cell lines. Molecular Carcinogenesis 56:4, pages 1251-1265.
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Xuewei Ye, Komal Anjum, Tengfei Song, Wenling Wang, Ying Liang, Mengxuan Chen, Haocai Huang, Xiao-Yuan Lian & Zhizhen Zhang. (2017) Antiproliferative cyclodepsipeptides from the marine actinomycete Streptomyces sp. P11-23B downregulating the tumor metabolic enzymes of glycolysis, glutaminolysis, and lipogenesis. Phytochemistry 135, pages 151-159.
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Donglai Lv, Shi-cang Yu, Yi-fang Ping, Haibo Wu, Xilong Zhao, Huarong Zhang, Youhong Cui, Bing Chen, Xia Zhang, Jianwu Dai, Xiu-wu Bian & Xiao-hong Yao. (2016) A three-dimensional collagen scaffold cell culture system for screening anti-glioma therapeutics. Oncotarget 7:35, pages 56904-56914.
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Christopher L. Plaisier, Sofie O’Brien, Brady Bernard, Sheila Reynolds, Zac Simon, Chad M. Toledo, Yu Ding, David J. Reiss, Patrick J. Paddison & Nitin S. Baliga. (2016) Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis. Cell Systems 3:2, pages 172-186.
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Belgin Sever, Mehlika Dilek Altıntop, Gökhan Kuş, Mete Özkurt, Ahmet Özdemir & Zafer Asım Kaplancıklı. (2016) Indomethacin based new triazolothiadiazine derivatives: Synthesis, evaluation of their anticancer effects on T98 human glioma cell line related to COX-2 inhibition and docking studies. European Journal of Medicinal Chemistry 113, pages 179-186.
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Ying Liang, Xin Xie, Lu Chen, Shilun Yan, Xuewei Ye, Komal Anjum, Haocai Huang, Xiaoyuan Lian & Zhizhen Zhang. (2016) Bioactive Polycyclic Quinones from Marine Streptomyces sp. 182SMLY. Marine Drugs 14:1, pages 10.
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Lu Chen, Ying Liang, Tengfei Song, Komal Anjum, Wenling Wang, Siran Yu, Haocai Huang, Xiao-Yuan Lian & Zhizhen Zhang. (2015) Synthesis and bioactivity of tripolinolate A from Tripolium vulgare and its analogs. Bioorganic & Medicinal Chemistry Letters 25:13, pages 2629-2633.
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Jian Wang, Yongli Li & Chuanlu Jiang. (2014) MiR-133b Contributes to Arsenic-Induced Apoptosis in U251 Glioma Cells by Targeting the hERG Channel. Journal of Molecular Neuroscience 55:4, pages 985-994.
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Xuewei Ye, Siran Yu, Ying Liang, Haocai Huang, Xiao-Yuan Lian & Zhizhen Zhang. (2014) Bioactive triterpenoid saponins and phenolic compounds against glioma cells. Bioorganic & Medicinal Chemistry Letters 24:22, pages 5157-5163.
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Siran Yu, Xuewei Ye, Lu Chen, Xiao-Yuan Lian & Zhizhen Zhang. (2014) Polyoxygenated 24,28-epoxyergosterols inhibiting the proliferation of glioma cells from sea anemone Anthopleura midori. Steroids 88, pages 19-25.
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Mithilesh Kumar JhaKyoungho Suk. (2013) Pyruvate Dehydrogenase Kinase as a Potential Therapeutic Target for Malignant Gliomas. Brain Tumor Research and Treatment 1:2, pages 57.
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