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Expert Opinion on Drug Discovery Volume 10, 2015 - Issue 4
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Review

Combining label-free cell phenotypic profiling with computational approaches for novel drug discovery

Ye FangCorning Inc., Biochemical Technologies, Science and Technology Division, Corning, NY 14831, [email protected]
Pages 331-343 | Published online: 01 Mar 2015

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Gargi Tiwari, Madan Singh Chauhan & Dipendra Sharma. (2022) Estimation of Binding Sites of Efavirenz with 3EO9 Receptor: In Silico Molecular Docking and Molecular Dynamics Studies. Polycyclic Aromatic Compounds 42:10, pages 7256-7266.
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Ye Fang. (2016) Compound annotation with real time cellular activity profiles to improve drug discovery. Expert Opinion on Drug Discovery 11:3, pages 269-280.
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Articles from other publishers (14)

Khac-Minh Thai, Thai-Son Tran, The-Huan Tran, Thi-Cam-Nhung Cao, Hoang-Nhan Ho, Phuong Nguyen Hoai Huynh, Tan Thanh Mai, Thanh-Dao Tran, Minh-Tri Le & Van-Thanh Tran. 2023. Computational Modeling of Drugs Against Alzheimer’s Disease. Computational Modeling of Drugs Against Alzheimer’s Disease 231 277 .
Hee June Choi, Chuangqi Wang, Xiang Pan, Junbong Jang, Mengzhi Cao, Joseph A BrazzoIIIIII, Yongho Bae & Kwonmoo Lee. (2021) Emerging machine learning approaches to phenotyping cellular motility and morphodynamics. Physical Biology 18:4, pages 041001.
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Maarten L.J. Doornbos & Laura H. Heitman. 2019. G Protein-Coupled Receptors, Part B. G Protein-Coupled Receptors, Part B 179 194 .
Julio Alves Cardoso Filho. 2019. Natural Bio-active Compounds. Natural Bio-active Compounds 1 40 .
Hao Sun, Yiting Shen, Guangwen Luo, Yuepiao Cai & Zheng Xiang. (2018) An integrated strategy for identifying new targets and inferring the mechanism of action: taking rhein as an example. BMC Bioinformatics 19:1.
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Maarten L.J. Doornbos, Ilse Van der Linden, Liesbeth Vereyken, Gary Tresadern, Adriaan P. IJzerman, Hilde Lavreysen & Laura H. Heitman. (2018) Constitutive activity of the metabotropic glutamate receptor 2 explored with a whole-cell label-free biosensor. Biochemical Pharmacology 152, pages 201-210.
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Jinlin Peng, Yaopeng Zhao, Yulong Hong, Robert S. Burkhalter, Carrie L. Hogue, Elizabeth Tran, Lai Wei, Lori Romeo, Paula Dolley-Sonneville, Zara Melkoumian, Xinmiao Liang & Ye Fang. (2018) Chemical Identity and Mechanism of Action and Formation of a Cell Growth Inhibitory Compound from Polycarbonate Flasks. Analytical Chemistry 90:7, pages 4603-4610.
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Y. Fang. 2019. Label-Free Monitoring of Cells in vitro. Label-Free Monitoring of Cells in vitro 189 217 .
Julia M. Hillger, Wai-Ling Lieuw, Laura H. Heitman & Adriaan P. IJzerman. (2017) Label-free technology and patient cells: from early drug development to precision medicine. Drug Discovery Today 22:12, pages 1808-1815.
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Y. Fang. 2017. Comprehensive Medicinal Chemistry III. Comprehensive Medicinal Chemistry III 416 433 .
J Romero-Durán, Edgar Lopez-Castro, Xerardo García-Mera & Humberto Gonzalez-Díaz. 2016. Biopolymers for Medical Applications. Biopolymers for Medical Applications 269 299 .
Wei Zhou, Yonghua Wang, Aiping Lu & Ge Zhang. (2016) Systems Pharmacology in Small Molecular Drug Discovery. International Journal of Molecular Sciences 17:2, pages 246.
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Heidi Hu, Huayun Deng & Ye Fang. 2016. Bioluminescence. Bioluminescence 3 17 .
Ye Fang. (2015) Are label-free investigations the best approach to drug discovery?. Future Medicinal Chemistry 7:12, pages 1561-1564.
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