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Volume 10, Issue 4

Expert Opinion on Drug Discovery

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Expert Opinion on Drug Discovery, Volume 10, Issue 4 (2015)

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Expert Opinion on Drug Discovery, Volume 10, Issue 4 (2015)

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Vol 19, 2024 Vol 18, 2023 Vol 17, 2022 Vol 16, 2021 Vol 15, 2020 Vol 14, 2019 Vol 13, 2018 Vol 12, 2017 Vol 11, 2016 Volume 10, 2015 Vol 9, 2014 Vol 8, 2013 Vol 7, 2012 Vol 6, 2011 Vol 5, 2010 Vol 4, 2009 Vol 3, 2008 Vol 2, 2007 Vol 1, 2006

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Editorial

Perspectives on lantibiotic discovery – where have we failed and what improvements are required?

Stephanie Kate Sandiford (Research Associate) PhD

Pages: 315-320

Published online: 19 Feb 2015

AbstractforPerspectives on lantibiotic discovery – where have we failed and what improvements are required? | Full Text | References | PDF (241.9 KB)

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Editorial

Maximizing computational tools for successful drug discovery

Chanin Nantasenamat & Virapong Prachayasittikul

Pages: 321-329

Published online: 18 Feb 2015

AbstractforMaximizing computational tools for successful drug discovery | Full Text | References | PDF (299.4 KB)

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Review

Combining label-free cell phenotypic profiling with computational approaches for novel drug discovery

Ye Fang

Pages: 331-343

Published online: 01 Mar 2015

AbstractforCombining label-free cell phenotypic profiling with computational approaches for novel drug discovery | Full Text | References | PDF (509.1 KB)

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Learning from structure-based drug design and new antivirals targeting the ribonucleoprotein complex for the treatment of influenza

Alexandre Monod, Christopher Swale, Bogdan Tarus, Alice Tissot, Bernard Delmas, Rob Wh Ruigrok, Thibaut Crépin & Anny Slama-Schwok

Pages: 345-371

Published online: 20 Mar 2015

AbstractforLearning from structure-based drug design and new antivirals targeting the ribonucleoprotein complex for the treatment of influenza | Full Text | References | PDF (2.6 MB)

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Approaches targeting the type III secretion system to treat or prevent bacterial infections

Nuno Charro (Post-Doctoral Fellow) PhD & Luís Jaime Mota (Assistant Professor) PhD

Pages: 373-387

Published online: 01 Mar 2015

AbstractforApproaches targeting the type III secretion system to treat or prevent bacterial infections | Full Text | References | PDF (483.8 KB)

506 Views
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Approaches for discovering anti-prion compounds: lessons learned and challenges ahead

Maria Laura Bolognesi (Professor) & Giuseppe Legname (Professor)

Pages: 389-397

Published online: 15 Feb 2015

AbstractforApproaches for discovering anti-prion compounds: lessons learned and challenges ahead | Full Text | References | PDF (394.3 KB)

356 Views
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Animal models for anti-emphysema drug discovery

Concetta Gardi (Assistant Professor of General Pathology) MSc PhD, Blerta Stringa (Research Fellow) MSc & Piero A Martorana (Retired) DVM MSc

Pages: 399-410

Published online: 23 Feb 2015

AbstractforAnimal models for anti-emphysema drug discovery | Full Text | References | PDF (482.2 KB)

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The use of natural products in colorectal cancer drug discovery

Koh Miura (Surgeon-in-Chief) , Masayuki Satoh, Makoto Kinouchi, Kuniharu Yamamoto, Yasuhiro Hasegawa, Yoichiro Kakugawa, Masaaki Kawai, Kiyoshi Uchimi, Hiroki Aizawa, Shinobu Ohnuma, Taiki Kajiwara, Hiroto Sakurai & Tsuneaki Fujiya

Pages: 411-426

Published online: 27 Feb 2015

AbstractforThe use of natural products in colorectal cancer drug discovery | Full Text | References | PDF (1.7 MB)

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Drug Discovery Case History

The discovery and development of sorafenib for the treatment of thyroid cancer

Peter T White (Research Fellow) MD & Mark S Cohen (Associate Professor of Surgery) MD

Pages: 427-439

Published online: 08 Feb 2015

AbstractforThe discovery and development of sorafenib for the treatment of thyroid cancer | Full Text | References | PDF (354 KB)

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