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Expert Opinion on Drug Discovery Volume 10, 2015 - Issue 9
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Review

X-ray crystallography over the past decade for novel drug discovery – where are we heading next?

Heping ZhengUniversity of Virginia, Department of Molecular Physiology and Biological Physics, 1340 Jefferson Park Avenue, Charlottesville, VA 22908, USA+1 434 243 6865; +1 434 243 2981; [email protected];Center for Structural Genomics of Infectious Diseases (CSGID), USA;New York Structural Genomics Research Consortium (NYSGRC), USA;Midwest Center for Structural Genomics (MCSG), USA
,
Katarzyna B HandingUniversity of Virginia, Department of Molecular Physiology and Biological Physics, 1340 Jefferson Park Avenue, Charlottesville, VA 22908, USA+1 434 243 6865; +1 434 243 2981; [email protected];New York Structural Genomics Research Consortium (NYSGRC), USA;Midwest Center for Structural Genomics (MCSG), USA
,
Matthew D ZimmermanUniversity of Virginia, Department of Molecular Physiology and Biological Physics, 1340 Jefferson Park Avenue, Charlottesville, VA 22908, USA+1 434 243 6865; +1 434 243 2981; [email protected];Center for Structural Genomics of Infectious Diseases (CSGID), USA;New York Structural Genomics Research Consortium (NYSGRC), USA;Midwest Center for Structural Genomics (MCSG), USA;Enzyme Function Initiative (EFI), USA
,
Ivan G ShabalinUniversity of Virginia, Department of Molecular Physiology and Biological Physics, 1340 Jefferson Park Avenue, Charlottesville, VA 22908, USA+1 434 243 6865; +1 434 243 2981; [email protected];Center for Structural Genomics of Infectious Diseases (CSGID), USA;New York Structural Genomics Research Consortium (NYSGRC), USA;Midwest Center for Structural Genomics (MCSG), USA
,
Steven C AlmoNew York Structural Genomics Research Consortium (NYSGRC), USA;Enzyme Function Initiative (EFI), USA;Albert Einstein College of Medicine, Department of Biochemistry, 1300 Morris Park Avenue, Bronx, NY 10461, USA
&
Wladek MinorUniversity of Virginia, Department of Molecular Physiology and Biological Physics, 1340 Jefferson Park Avenue, Charlottesville, VA 22908, USA+1 434 243 6865; +1 434 243 2981; [email protected];Center for Structural Genomics of Infectious Diseases (CSGID), USA;New York Structural Genomics Research Consortium (NYSGRC), USA;Midwest Center for Structural Genomics (MCSG), USA;Enzyme Function Initiative (EFI), USA
Pages 975-989 | Published online: 15 Jul 2015

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Vanessa Bijak, Michal Szczygiel, Joanna Lenkiewicz, Michal Gucwa, David R. Cooper, Krzysztof Murzyn & Wladek Minor. (2023) The current role and evolution of X-ray crystallography in drug discovery and development. Expert Opinion on Drug Discovery 18:11, pages 1221-1230.
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Visvaldas Kairys, Lina Baranauskiene, Migle Kazlauskiene, Daumantas Matulis & Egidijus Kazlauskas. (2019) Binding affinity in drug design: experimental and computational techniques. Expert Opinion on Drug Discovery 14:8, pages 755-768.
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Martin Klumpp. (2016) Non-stoichiometric inhibition in integrated lead finding – a literature review. Expert Opinion on Drug Discovery 11:2, pages 149-162.
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