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Review

Biological role of α-fetoprotein in cancer: prospects for anticancer therapy

Pages 709-735 | Published online: 10 Jan 2014

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Baocuo Gong, Xuewen Wang, Wanting Guo, Hongyi Yang, Yanhong Shi, Yaying Chen, Simiao Gao, Jialin Chen, Lifang Liu, Linbin Lu & Xiong Chen. (2023) Prognosis of Patients with Hepatocellular Carcinoma Treated with Transarterial Chemoembolization(MC-hccAI 001): Development and Validation of the ALFP Score. Journal of Hepatocellular Carcinoma 10, pages 1341-1351.
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Nisha A. Lakhi & Gerald J. Mizejewski. (2017) Alpha-fetoprotein and Fanconi Anemia: Relevance to DNA Repair and Breast Cancer Susceptibility. Fetal and Pediatric Pathology 36:1, pages 49-61.
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Fan Zhou, Zengyao Li, Zengtao Bao, Kang Feng, Ye Zhang & Tong Wang. (2015) Highly sensitive, label-free and real-time detection of alpha-fetoprotein using a silicon nanowire biosensor. Scandinavian Journal of Clinical and Laboratory Investigation 75:7, pages 578-584.
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GJ Mizejewski, M Mirowski, P Garnuszek, M Maurin, BD Cohen, BJ Poiesz, GA Posypanova, VA Makarov, ES Severin & SE Severin. (2010) Targeted delivery of anti-cancer growth inhibitory peptides derived from human α-fetoprotein: review of an International Multi-Center Collaborative Study. Journal of Drug Targeting 18:8, pages 575-588.
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Deepti Srinivas Wilkinson, Wen-Wei Tsai, Maria A. Schumacher & Michelle Craig Barton. (2008) Chromatin-Bound p53 Anchors Activated Smads and the mSin3A Corepressor To Confer Transforming Growth Factor β-Mediated Transcription Repression. Molecular and Cellular Biology 28:6, pages 1988-1998.
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Vandana M. SagarKathyrn HerringStuart Curbishley, James Hodson, Peter Fletcher, Salil Karkhanis, Homoyon Mehrzad, Pankaj Punia, Tahir Shah, Shishir ShettyYuk Ting Ma. (2021) The potential of PIVKA-II as a treatment response biomarker in hepatocellular carcinoma: a prospective United Kingdom cohort study. Oncotarget 12:24, pages 2338-2350.
Crossref
Snehasis Bhakta & Prashant Mishra. (2021) Molecularly imprinted polymer-based sensors for cancer biomarker detection. Sensors and Actuators Reports 3, pages 100061.
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Bo Lin, Xu Dong, Qiujiao Wang, Wei Li, Mingyue Zhu & Mengsen Li. (2021) AFP-Inhibiting Fragments for Drug Delivery: The Promise and Challenges of Targeting Therapeutics to Cancers. Frontiers in Cell and Developmental Biology 9.
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Nurbubu Moldogazieva, Innokenty Mokhosoev, Sergey Zavadskiy & Alexander Terentiev. (2021) Proteomic Profiling and Artificial Intelligence for Hepatocellular Carcinoma Translational Medicine. Biomedicines 9:2, pages 159.
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O. K. Gulevskyy. (2021) URRENT CONCEPT OF THE STRUCTURAL AND FUNCTIONAL PROPERTIES OF ALFA-FETOPROTEIN AND THE POSSIBILITIES OF ITS CLINICAL APPLICATION. Biotechnologia Acta 14:1, pages 25-37.
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Hebatallah Adel Sedky, Soha Raouf Youssef, Doaa Ahmad Gamal, Heba Fawzy Houssein & Walaa Ali Elsalakawy. (2020) First report of the unique expression of RECAF (receptor for alfa feto-protein) in adult B-NHL/CLL patients. BLOOD RESEARCH 55:4, pages 253-261.
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Tianke Chen, Xiaowei Dai, Juji Dai, Chaodong Ding, Zheng Zhang, Ziqi Lin, Jin Hu, Mei Lu, Zhanyu Wang, Yalei Qi, Li Zhang, Rulu Pan, Zhu Zhao, Liting Lu, Wanqin Liao & Xincheng Lu. (2020) AFP promotes HCC progression by suppressing the HuR-mediated Fas/FADD apoptotic pathway. Cell Death & Disease 11:10.
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Zhenjuan Li, Haiping Gong, Qiuping Liu, Wanli Wu, Jianting Cheng, Yingyi Mei, Yaolong Chen, Hongjun Zheng, Xiaohong Yu, Shi Zhong & Yi Li. (2020) Identification of an HLA‐A*24:02‐restricted α ‐fetoprotein signal peptide‐derived antigen and its specific T‐cell receptor for T‐cell immunotherapy . Immunology 159:4, pages 384-392.
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Nurbubu T. Moldogazieva, Daria S. Ostroverkhova, Nikolai N. Kuzmich, Vladimir V. Kadochnikov, Alexander A. Terentiev & Yuri B. Porozov. (2020) Elucidating Binding Sites and Affinities of ERα Agonists and Antagonists to Human Alpha-Fetoprotein by In Silico Modeling and Point Mutagenesis. International Journal of Molecular Sciences 21:3, pages 893.
Crossref
Patric Teodorescu, Sergiu Pasca & Ciprian Tomuleasa. 2020. Pineal Region Lesions. Pineal Region Lesions 45 49 .
Robert Montal, Carmen Andreu-Oller, Laia Bassaganyas, Roger Esteban-Fabró, Sebastián Moran, Carla Montironi, Agrin Moeini, Roser Pinyol, Judit Peix, Laia Cabellos, Augusto Villanueva, Daniela Sia, Vincenzo Mazzaferro, Manel Esteller & Josep M. Llovet. (2019) Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials. British Journal of Cancer 121:4, pages 340-343.
Crossref
Patricia M. Santos, Ashley V. Menk, Jian Shi, Allan Tsung, Greg M. Delgoffe & Lisa H. Butterfield. (2019) Tumor-Derived α-Fetoprotein Suppresses Fatty Acid Metabolism and Oxidative Phosphorylation in Dendritic Cells. Cancer Immunology Research 7:6, pages 1001-1012.
Crossref
A. Rizzo, M. Galgano, M. Mutinati & R.L. Sciorsci. (2019) Alpha-fetoprotein in animal reproduction. Research in Veterinary Science 123, pages 281-285.
Crossref
Wasila Mansouri, Samuel B. Fordyce, Matthew Wu, David Jones, Douglas Cohn, Qishan Lin, Paul Feustel, Tanuj Sharma, James A. Bennett & Thomas T. Andersen. (2018) Efficacy and tolerability of AFPep, a cyclic peptide with anti-breast cancer properties. Toxicology and Applied Pharmacology 345, pages 10-18.
Crossref
Mehran Afshar, Peter Fletcher, Antonio D Bardoli, Yuk Ting Ma & Pankaj Punia. (2018) Non-secretion of AFP and neutrophil lymphocyte ratio as predictors for survival in hepatocellular carcinoma patients treated with sorafenib: a large UK cohort. Oncotarget 9:24, pages 16988-16995.
Crossref
Murad Mollaev, Neonila Gorokhovets, Elena Nikolskaya, Maria Faustova, Arthur Zabolotsky, Maria Sokol, Oksana Tereshenko, Olga Zhunina, Vitaliy Shvets, Evgeniy Severin & Nikita Yabbarov. (2018) Recombinant alpha-fetoprotein receptor-binding domain co-expression with polyglutamate tags facilitates in vivo folding in E. coli. Protein Expression and Purification 143, pages 77-82.
Crossref
Nikolai N. Belyaev, Nurshat Abdolla, Yuliya V. Perfilyeva, Yekaterina O. Ostapchuk, Vladimir K. Krasnoshtanov, Aikyn Kali & Raikhan Tleulieva. (2017) Daunorubicin conjugated with alpha-fetoprotein selectively eliminates myeloid-derived suppressor cells (MDSCs) and inhibits experimental tumor growth. Cancer Immunology, Immunotherapy 67:1, pages 101-111.
Crossref
Amr A. Fouad, Hatem O. Qutub, Abdullatif S. Al Rashed & Walid N. Al-Melhim. (2017) Therapeutic effect of carnosine in rat model of experimental liver carcinogenesis. Environmental Toxicology and Pharmacology 56, pages 10-14.
Crossref
Bo Lin, Guoqing Peng, Haipeng Feng, Wei Li, Xu Dong, Yi Chen, Yan Lu, Qiaoyun Wang, Xieju Xie, Mingyue Zhu & Mengsen Li. (2017) Purification and characterization of a bioactive alpha-fetoprotein produced by HEK-293 cells. Protein Expression and Purification 136, pages 1-6.
Crossref
Kiyoshi Ohkawa, Tadashi Asakura, Yutaka Tsukada & Tomokazu Matsuura. (2017) Antibody to human α-fetoprotein inhibits cell growth of human hepatocellular carcinoma cells by resuscitating the PTEN molecule: in vitro experiments. International Journal of Oncology 50:6, pages 2180-2190.
Crossref
Raheleh Shakeri, Asma Kheirollahi & Jamshid Davoodi. (2017) Apaf-1: Regulation and function in cell death. Biochimie 135, pages 111-125.
Crossref
Massimiliano Berretta, Carla Cavaliere, Lara Alessandrini, Brigida Stanzione, Gaetano Facchini, Luca Balestreri, Tiziana Perin & Vincenzo Canzonieri. (2016) Serum and tissue markers in hepatocellular carcinoma and cholangiocarcinoma: clinical and prognostic implications. Oncotarget 8:8, pages 14192-14220.
Crossref
Stephen L. Chan, Anthony W. H. Chan & Simon C. H. Yu. 2017. Biomarkers in Liver Disease. Biomarkers in Liver Disease 623 635 .
Chao Zhang, Hui Li, Wei Jiang, Xiaowei Zhang & Gang Li. (2016) Icaritin inhibits the expression of alpha-fetoprotein in hepatitis B virus-infected hepatoma cell lines through post-transcriptional regulation. Oncotarget 7:50, pages 83755-83766.
Crossref
G. J. Mizejewski. (2016) The alpha-fetoprotein (AFP) third domain: a search for AFP interaction sites of cell cycle proteins. Tumor Biology 37:9, pages 12697-12711.
Crossref
Lisa H. Butterfield. (2016) Lessons learned from cancer vaccine trials and target antigen choice. Cancer Immunology, Immunotherapy 65:7, pages 805-812.
Crossref
Huixiao Hong, Jie Shen, Hui Ng, Sugunadevi Sakkiah, Hao Ye, Weigong Ge, Ping Gong, Wenming Xiao & Weida Tong. (2016) A Rat α-Fetoprotein Binding Activity Prediction Model to Facilitate Assessment of the Endocrine Disruption Potential of Environmental Chemicals. International Journal of Environmental Research and Public Health 13:4, pages 372.
Crossref
Stephen L. Chan, Anthony W. H. Chan & Simon C. H. Yu. 2016. Biomarkers in Liver Disease. Biomarkers in Liver Disease 1 13 .
Angela D. Pardee, Hiroshi Yano, Aliyah M. Weinstein, Aaron A. K. Ponce, Alexander D. Ethridge, Daniel P. Normolle, Lazar Vujanovic, Gerald J. Mizejewski, Simon C. Watkins & Lisa H. Butterfield. (2015) Route of antigen delivery impacts the immunostimulatory activity of dendritic cell-based vaccines for hepatocellular carcinoma. Journal for ImmunoTherapy of Cancer 3:1.
Crossref
G. J. Mizejewski. (2015) Nonsecreted cytoplasmic alpha-fetoprotein: a newly discovered role in intracellular signaling and regulation. An update and commentary. Tumor Biology 36:12, pages 9857-9864.
Crossref
Chao Zhang, Xiangmei Chen, Hui Liu, Hui Li, Wei Jiang, Wenting Hou, Michael A. McNutt, Fengmin Lu & Gang Li. (2015) Alpha fetoprotein mediates HBx induced carcinogenesis in the hepatocyte cytoplasm. International Journal of Cancer 137:8, pages 1818-1829.
Crossref
Roula Tahtouh, Anne-Sophie Azzi, Nada Alaaeddine, Soulaima Chamat, Hasnaa Bouharoun-Tayoun, Layal Wardi, Issam Raad, Riad Sarkis, Najibe Abou Antoun & George Hilal. (2015) Telomerase Inhibition Decreases Alpha-Fetoprotein Expression and Secretion by Hepatocellular Carcinoma Cell Lines: In Vitro and In Vivo Study. PLOS ONE 10:3, pages e0119512.
Crossref
Mingyue Zhu, Junli Guo, Hua Xia, Wei Li, Yan Lu, Xu Dong, Yi Chen, Xieju Xie, Shigan Fu & Mengsen Li. (2015) Alpha-fetoprotein activates AKT/mTOR signaling to promote CXCR4 expression and migration of hepatoma cells. Oncoscience 2:1, pages 59-70.
Crossref
Angela D. Pardee, Jian Shi & Lisa H. Butterfield. (2014) Tumor-Derived α-Fetoprotein Impairs the Differentiation and T Cell Stimulatory Activity of Human Dendritic Cells. The Journal of Immunology 193:11, pages 5723-5732.
Crossref
Jun Zhang, Rui Wang, Min Cai, Shunji Yu, Yanyun Ma, Weihong Xu, Chunfang Gao, Jiucun Wang, Lifang Hou, Yi Liu & Jie Liu. (2014) Association of microRNA-3144 variant with the susceptibility to hepatocellular carcinoma. Genes & Genomics 36:6, pages 771-776.
Crossref
Vladimir Pak. (2014) The use of α-fetoprotein for the delivery of cytotoxic payloads to cancer cells. Therapeutic Delivery 5:8, pages 885-892.
Crossref
Lisa H Butterfield, James S Economou, T Gamblin & David A Geller. (2014) Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients. Journal of Translational Medicine 12:1, pages 86.
Crossref
Ekaterina Zubkova, Lidiya Semenkova, Elena Dudich, Igor Dudich, Yelena Parfyonova & Mikhail Menshikov. (2013) RETRACTED ARTICLE: Alpha-fetoprotein contributes to THP-1 cell invasion and chemotaxis via protein kinase and Gi-protein-dependent pathways. Molecular and Cellular Biochemistry 379:1-2, pages 283-293.
Crossref
Huixiao Hong, William S. Branham, Stacey L. Dial, Carrie L. Moland, Hong Fang, Jie Shen, Roger Perkins, Daniel Sheehan & Weida Tong. (2012) Rat α-Fetoprotein Binding Affinities of a Large Set of Structurally Diverse Chemicals Elucidated the Relationships between Structures and Binding Affinities. Chemical Research in Toxicology 25:11, pages 2553-2566.
Crossref
Gaetano Bertino, Annalisa Ardiri, Michele Malaguarnera, Giulia Malaguarnera, Nicoletta Bertino & Giuseppe Stefano Calvagno. (2012) Hepatocellualar Carcinoma Serum Markers. Seminars in Oncology 39:4, pages 410-433.
Crossref
Shanshan Wang, Wei Jiang, Xiangmei Chen, Chao Zhang, Hui Li, Wenting Hou, Zhongmin Liu, Michael A. McNutt, Fengmin Lu & Gang Li. (2012) Alpha-fetoprotein acts as a novel signal molecule and mediates transcription of Fn14 in human hepatocellular carcinoma. Journal of Hepatology 57:2, pages 322-329.
Crossref
Goshi Shiota & Norimasa Miura. (2012) Biomarkers for hepatocellular carcinoma. Clinical Journal of Gastroenterology 5:3, pages 177-182.
Crossref
A. V. Morozov, V. A. Morozov, T. M. Astakhova, A. V. Timofeev & V. L. Karpov. (2012) DNA vaccine encoding α-fetoprotein fused with the ornithine decarboxylase degradation signal significantly suppresses the hepatocellular carcinoma growth in mice. Molecular Biology 46:3, pages 391-406.
Crossref
ALEXANDER A. TERENTIEV, NURBUBU T. MOLDOGAZIEVA, OLGA V. LEVTSOVA, DMITRY M. MAXIMENKO, DENIS A. BOROZDENKO & KONSTANTIN V. SHAITAN. (2012) MODELING OF THREE DIMENSIONAL STRUCTURE OF HUMAN ALPHA-FETOPROTEIN COMPLEXED WITH DIETHYLSTILBESTROL: DOCKING AND MOLECULAR DYNAMICS SIMULATION STUDY. Journal of Bioinformatics and Computational Biology 10:02, pages 1241012.
Crossref
Chaoying Li, Shanshan Wang, Wei Jiang, Hui Li, Zhongmin Liu, Chao Zhang, Michael A. McNutt & Gang Li. (2011) Impact of intracellular alpha fetoprotein on retinoic acid receptors‐mediated expression of GADD153 in human hepatoma cell lines. International Journal of Cancer 130:4, pages 754-764.
Crossref
Gerald Mizejewski. (2011) Mechanism of Cancer Growth Suppression of Alpha-Fetoprotein Derived Growth Inhibitory Peptides (GIP): Comparison of GIP-34 versus GIP-8 (AFPep). Updates and Prospects. Cancers 3:2, pages 2709-2733.
Crossref
Gerald J. Mizejewski. (2010) Review of the putative cell-surface receptors for alpha-fetoprotein: identification of a candidate receptor protein family. Tumor Biology 32:2, pages 241-258.
Crossref
Giulia Malaguarnera, Maria Giordano, Isabella Paladina, Massimiliano Berretta, Alessandro Cappellani & Mariano Malaguarnera. (2010) Serum Markers of Hepatocellular Carcinoma. Digestive Diseases and Sciences 55:10, pages 2744-2755.
Crossref
Penelope Brock, Derek J. Roebuck & Jack Plaschkes. 2010. Pediatric Hematology and Oncology. Pediatric Hematology and Oncology 258 274 .
Herbert I. Jacobson, Nicole Lemanski, Anu Agarwal, Amithi Narendran, Kelvin E. TurnerIIII, James A. Bennett & Thomas T. Andersen. (2010) A Proposed Unified Mechanism for the Reduction of Human Breast Cancer Risk by the Hormones of Pregnancy. Cancer Prevention Research 3:2, pages 212-220.
Crossref
Xavier Rogiers & Ruth De Bruyne. 2010. Malignant Liver Tumors. Malignant Liver Tumors 475 486 .
AI Potapovich, S Pastore, VA Kostyuk, D Lulli, V Mariani, C De Luca, EI Dudich & LG Korkina. (2009) α‐Fetoprotein as a modulator of the pro‐inflammatory response of human keratinocytes. British Journal of Pharmacology 158:5, pages 1236-1247.
Crossref
Mengsen Li, Hui Li, Chaoying Li, Liyuan Guo, Han Liu, Sheng Zhou, Xinhua Liu, Zhuo Chen, Shuanglin Shi, Jiang Wei, Michael A. McNutt & Gang Li. (2009) Cytoplasmic alpha-fetoprotein functions as a co-repressor in RA-RAR signaling to promote the growth of human hepatoma Bel 7402 cells. Cancer Letters 285:2, pages 190-199.
Crossref
Stephen L Chan, Anthony TC Chan & Winnie Yeo. (2009) Role of α-fetoprotein in hepatocellular carcinoma: prognostication, treatment monitoring or both?. Future Oncology 5:6, pages 889-899.
Crossref
Gerald J. Mizejewski. (2008) Alpha-fetoprotein (AFP)-derived peptides as epitopes for hepatoma immunotherapy: a commentary. Cancer Immunology, Immunotherapy 58:2, pages 159-170.
Crossref
Rajasree Menon, Qing Zhang, Yan Zhang, Damian Fermin, Nabeel Bardeesy, Ronald A. DePinho, Chunxia Lu, Samir M. Hanash, Gilbert S. Omenn & David J. States. (2009) Identification of Novel Alternative Splice Isoforms of Circulating Proteins in a Mouse Model of Human Pancreatic Cancer. Cancer Research 69:1, pages 300-309.
Crossref
Jung Rok Lee, Juhee Lee, Sang Kyung Kim, Kwang Pyo Kim, Hyung Soon Park & Woon-Seok Yeo. (2008) Mass Spectrometry Signal Amplification Method for Attomolar Detection of Antigens Using Small-Molecule-Tagged Gold Microparticles. Angewandte Chemie International Edition 47:49, pages 9518-9521.
Crossref
Jung Rok Lee, Juhee Lee, Sang Kyung Kim, Kwang Pyo Kim, Hyung Soon Park & Woon-Seok Yeo. (2008) Mass Spectrometry Signal Amplification Method for Attomolar Detection of Antigens Using Small-Molecule-Tagged Gold Microparticles. Angewandte Chemie 120:49, pages 9660-9663.
Crossref
Xiaojun Yang, Youcheng Zhang, Lingyi Zhang, Lin Zhang & Jie Mao. (2008) Silencing alpha-fetoprotein expression induces growth arrest and apoptosis in human hepatocellular cancer cell. Cancer Letters 271:2, pages 281-293.
Crossref
Noboru Mitsuhashi, Souichi Kobayashi, Tomoko Doki, Fumio Kimura, Hiroaki Shimizu, Hiroyuki Yoshidome, Masayuki Ohtsuka, Atsushi Kato, Hideyuki Yoshitomi, Satoshi Nozawa, Katsunori Furukawa, Dan Takeuchi, Kosuke Suda, Seiki Miura & Masaru Miyazaki. (2008) Clinical significance of -fetoprotein: involvement in proliferation, angiogenesis, and apoptosis of hepatocellular carcinoma. Journal of Gastroenterology and Hepatology 23:7pt2, pages e189-e197.
Crossref
Gerald J. Mizejewski. (2016) Physiology of Alpha-Fetoprotein as a Biomarker for Perinatal Distress: Relevance to Adverse Pregnancy Outcome. Experimental Biology and Medicine 232:8, pages 993-1004.
Crossref
Dolores López-Terrada & Milton J. Finegold. 2009. Liver Disease in Children. Liver Disease in Children 943 974 .
Gerald J. Mizejewski. (2007) The Alpha-Fetoprotein–Derived Growth Inhibitory Peptide 8-Mer Fragment: Review of a Novel Anticancer Agent. Cancer Biotherapy and Radiopharmaceuticals 22:1, pages 73-98.
Crossref
A. A. Terentiev & N. T. Moldogazieva. (2006) Structural and functional mapping of α-fetoprotein. Biochemistry (Moscow) 71:2, pages 120-132.
Crossref
Jiong Zhou, Takashi Suzuki, Agnes Kovacic, Ryoko Saito, Yasuhiro Miki, Takanori Ishida, Takuya Moriya, Evan R. Simpson, Hironobu Sasano & Colin D. Clyne. (2005) Interactions between Prostaglandin E2, Liver Receptor Homologue-1, and Aromatase in Breast Cancer. Cancer Research 65:2, pages 657-663.
Crossref
O. N. Ilinskaya & A. A. Makarov. (2005) Why ribonucleases induce tumor cell death. Molecular Biology 39:1, pages 1-10.
Crossref
Shian‐Yang Peng, Wei J. Chen, Po‐Lin Lai, Yun‐Ming Jeng, Jin‐Chuan Sheu & Hey‐Chi Hsu. (2004) High α‐fetoprotein level correlates with high stage, early recurrence and poor prognosis of hepatocellular carcinoma: Significance of hepatitis virus infection, age, p53 and β‐catenin mutations. International Journal of Cancer 112:1, pages 44-50.
Crossref
Lakita G. Cavin, Manickam Venkatraman, Valentina M. Factor, Swayamjot Kaur, Insa Schroeder, Frank Mercurio, Amer A. Beg, Snorri S. Thorgeirsson & Marcello Arsura. (2004) Regulation of α-Fetoprotein by Nuclear Factor-κB Protects Hepatocytes from Tumor Necrosis Factor-α Cytotoxicity during Fetal Liver Development and Hepatic Oncogenesis. Cancer Research 64:19, pages 7030-7038.
Crossref
Gerald J. Mizejewski. (2016) Biological Roles of Alpha-Fetoprotein During Pregnancy and Perinatal Development. Experimental Biology and Medicine 229:6, pages 439-463.
Crossref

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