Citations (43)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (2)
Lichun Sun, Qingqing Qian, Guangchun Sun, L. Vienna Mackey, Joseph A. Fuselier, David H. Coy & Cui-Yun Yu. (2016) Valproic acid induces NET cell growth arrest and enhances tumor suppression of the receptor-targeted peptide–drug conjugate via activating somatostatin receptor type II. Journal of Drug Targeting 24:2, pages 169-177.
Read now
Read now
Meng-Meng Ji, Li Wang, Qin Zhan, Wen Xue, Yan Zhao, Xia Zhao, Peng-Peng Xu, Yang Shen, Han Liu, Anne Janin, Shu Cheng & Wei-Li Zhao. (2015) Induction of autophagy by valproic acid enhanced lymphoma cell chemosensitivity through HDAC-independent and IP3-mediated PRKAA activation. Autophagy 11:12, pages 2160-2171.
Read now
Read now
Articles from other publishers (41)
Mahdieh Meschi, Khatereh Khorsandi & Zahra Kianmehr. (2023) The Effect of Berberine Follow by Blue Light Irradiation and Valproic Acid on the Growth Inhibition of MDA-MB-231 Breast Cancer Cells. Applied Biochemistry and Biotechnology 195:11, pages 6752-6767.
Crossref
Crossref
Veronika Antonyová, Ameneh Tatar, Tereza Brogyányi, Zdeněk Kejík, Robert Kaplánek, Fréderic Vellieux, Nikita Abramenko, Alla Sinica, Jan Hajduch, Petr Novotný, Bettie Sue Masters, Pavel Martásek & Milan Jakubek. (2022) Targeting of the Mitochondrial TET1 Protein by Pyrrolo[3,2-b]pyrrole Chelators. International Journal of Molecular Sciences 23:18, pages 10850.
Crossref
Crossref
Margarita E. Neganova, Sergey G. Klochkov, Yulia R. Aleksandrova & Gjumrakch Aliev. (2022) Histone modifications in epigenetic regulation of cancer: Perspectives and achieved progress. Seminars in Cancer Biology 83, pages 452-471.
Crossref
Crossref
Federico Cucchiara, Sara Ferraro, Giacomo Luci & Guido Bocci. (2022) Relevant pharmacological interactions between alkylating agents and antiepileptic drugs: Preclinical and clinical data. Pharmacological Research 175, pages 105976.
Crossref
Crossref
Alan Talevi. 2022. Comprehensive Pharmacology. Comprehensive Pharmacology
813
824
.
T. Numan, S. D. Kulik, B. Moraal, J. C. Reijneveld, C. J. Stam, P. C. de Witt Hamer, J. Derks, A. M. E. Bruynzeel, M. E. van Linde, P. Wesseling, M. C. M. Kouwenhoven, M. Klein, T. Würdinger, F. Barkhof, J. J. G. Geurts, A. Hillebrand & L. Douw. (2021) Non-invasively measured brain activity and radiological progression in diffuse glioma. Scientific Reports 11:1.
Crossref
Crossref
Mehrnaz Jahani, Hossein Khanahmad & Parvaneh Nikpour. (2020) Evaluation of the Effects of Valproic Acid Treatment on Cell Survival and Epithelial-Mesenchymal Transition-Related Features of Human Gastric Cancer Cells. Journal of Gastrointestinal Cancer 52:2, pages 676-681.
Crossref
Crossref
Katarzyna Lipska, Anna Gumieniczek, Rafał Pietraś & Agata A. Filip. (2021) HPLC-UV and GC-MS Methods for Determination of Chlorambucil and Valproic Acid in Plasma for Further Exploring a New Combined Therapy of Chronic Lymphocytic Leukemia. Molecules 26:10, pages 2903.
Crossref
Crossref
Chiara Parodi, Elisabetta Di Fede, Angela Peron, Ilaria Viganò, Paolo Grazioli, Silvia Castiglioni, Richard H. Finnell, Cristina Gervasini, Aglaia Vignoli & Valentina Massa. (2021) Chromatin Imbalance as the Vertex Between Fetal Valproate Syndrome and Chromatinopathies. Frontiers in Cell and Developmental Biology 9.
Crossref
Crossref
Priti Jain, Shreyans K. Jain & Munendra Jain. (2021) Harnessing Drug Repurposing for Exploration of New Diseases: An Insight to Strategies and Case Studies. Current Molecular Medicine 21:2, pages 111-132.
Crossref
Crossref
Jeffrey I Traylor, Hadley E Sheppard, Visweswaran Ravikumar, Jonathan Breshears, Shaan M Raza, Charles Y Lin, Shreyaskumar R Patel & Franco DeMonte. (2021) Computational Drug Repositioning Identifies Potentially Active Therapies for Chordoma. Neurosurgery 88:2, pages 428-436.
Crossref
Crossref
Chen qi Zhang, Bao ming He, Mei ling Hu & Hong bin Sun. (2020) Risk of Valproic Acid-Related Tremor: A Systematic Review and Meta-Analysis. Frontiers in Neurology 11.
Crossref
Crossref
Afton Chavez, Charles P. QuesenberryJr.Jr., Jeanne Darbinian & Maryam M. Asgari. (2020) Association of Valproic Acid Use, a Potent Histone Deacetylase Inhibitor, and Melanoma Risk. Journal of Investigative Dermatology 140:12, pages 2353-2358.
Crossref
Crossref
Luca Hegedűs, Dominika Rittler, Tamás Garay, Paul Stockhammer, Ildikó Kovács, Balázs Döme, Sarah Theurer, Thomas Hager, Thomas Herold, Stavros Kalbourtzis, Agnes Bankfalvi, Kurt W. Schmid, Dagmar Führer, Clemens Aigner & Balázs Hegedűs. (2020) HDAC Inhibition Induces PD-L1 Expression in a Novel Anaplastic Thyroid Cancer Cell Line. Pathology & Oncology Research 26:4, pages 2523-2535.
Crossref
Crossref
Katarzyna Lipska, Anna Gumieniczek & Agata A. Filip. (2020) Anticonvulsant valproic acid and other short-chain fatty acids as novel anticancer therapeutics: Possibilities and challenges. Acta Pharmaceutica 70:3, pages 291-301.
Crossref
Crossref
Renata S. Scalco, Mads Stemmerik, Nicoline Løkken, Christoffer R. Vissing, Karen L. Madsen, Zuzanna Michalak, Jatin Pattni, Richard Godfrey, George Samandouras, Paul Bassett, Janice L. Holton, Thomas Krag, Ronald G. Haller, C. Sewry, Ralph Wigley, John Vissing & Ros Quinlivan. (2020) Results of an open label feasibility study of sodium valproate in people with McArdle disease. Neuromuscular Disorders 30:9, pages 734-741.
Crossref
Crossref
Yudibeth Sixto-López, Martiniano Bello & José Correa-Basurto. (2020) Exploring the inhibitory activity of valproic acid against the HDAC family using an MMGBSA approach. Journal of Computer-Aided Molecular Design 34:8, pages 857-878.
Crossref
Crossref
Federico Cucchiara, Francesco Pasqualetti, Filippo Sean Giorgi, Romano Danesi & Guido Bocci. (2020) Epileptogenesis and oncogenesis: An antineoplastic role for antiepileptic drugs in brain tumours?. Pharmacological Research 156, pages 104786.
Crossref
Crossref
Shan-Ju Yeh, Shuo-Wei Chen & Bor-Sen Chen. (2020) Investigation of the Genome-Wide Genetic and Epigenetic Networks for Drug Discovery Based on Systems Biology Approaches in Colorectal Cancer. Frontiers in Genetics 11.
Crossref
Crossref
Sohini Chakraborti, Pushpaveni Chakravarthi & Narayanaswamy Srinivasan. 2020. Drug Repurposing in Cancer Therapy. Drug Repurposing in Cancer Therapy
15
54
.
F. de Oliveira Andrade, N. M. Nguyen, A. Warri & L. Hilakivi-Clarke. (2019) Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy. Scientific Reports 9:1.
Crossref
Crossref
A. Ganesan, Paola B. Arimondo, Marianne G. Rots, Carmen Jeronimo & María Berdasco. (2019) The timeline of epigenetic drug discovery: from reality to dreams. Clinical Epigenetics 11:1.
Crossref
Crossref
Theresa K. Leslie, Andrew D. James, Fulvio Zaccagna, James T. Grist, Surrin Deen, Aneurin Kennerley, Frank Riemer, Joshua D. Kaggie, Ferdia A. Gallagher, Fiona J. Gilbert & William J. Brackenbury. (2019) Sodium homeostasis in the tumour microenvironment. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1872:2, pages 188304.
Crossref
Crossref
Oguzhan Akgun, Merve Erkisa & Ferda Ari. (2019) Effective and new potent drug combination: Histone deacetylase and Wnt/β‐catenin pathway inhibitors in lung carcinoma cells. Journal of Cellular Biochemistry 120:9, pages 15467-15482.
Crossref
Crossref
Justyna Kocik, Monika Machula, Aneta Wisniewska, Ewa Surmiak, Tad A. Holak & Lukasz Skalniak. (2019) Helping the Released Guardian: Drug Combinations for Supporting the Anticancer Activity of HDM2 (MDM2) Antagonists. Cancers 11:7, pages 1014.
Crossref
Crossref
Rashmi R. Shah & Peter D. Stonier. (2019) Repurposing old drugs in oncology: Opportunities with clinical and regulatory challenges ahead. Journal of Clinical Pharmacy and Therapeutics 44:1, pages 6-22.
Crossref
Crossref
Farnaz Barneh, Mona Salimi, Fatemeh Goshadrou, Minoo Ashtiani, Mehdi Mirzaie, Hakimeh Zali & Mohieddin Jafari. (2018) Valproic acid inhibits the protective effects of stromal cells against chemotherapy in breast cancer: Insights from proteomics and systems biology. Journal of Cellular Biochemistry 119:11, pages 9270-9283.
Crossref
Crossref
Asadollah Mohammadi, Atefeh Sharifi, Reza Pourpaknia, Saeed Mohammadian & Amirhossein Sahebkar. (2018) Manipulating macrophage polarization and function using classical HDAC inhibitors: Implications for autoimmunity and inflammation. Critical Reviews in Oncology/Hematology 128, pages 1-18.
Crossref
Crossref
Beste Turanli, Morten Grøtli, Jan Boren, Jens Nielsen, Mathias Uhlen, Kazim Y. Arga & Adil Mardinoglu. (2018) Drug Repositioning for Effective Prostate Cancer Treatment. Frontiers in Physiology 9.
Crossref
Crossref
Nazlıhan Aztopal, Merve Erkisa, Elif Erturk, Engin Ulukaya, Asuman Hatice Tokullugil & Ferda Ari. (2018) Valproic acid, a histone deacetylase inhibitor, induces apoptosis in breast cancer stem cells. Chemico-Biological Interactions 280, pages 51-58.
Crossref
Crossref
Manuela Terranova-Barberio, Biagio Pecori, Maria Serena Roca, Serena Imbimbo, Francesca Bruzzese, Alessandra Leone, Paolo Muto, Paolo Delrio, Antonio Avallone, Alfredo Budillon & Elena Di Gennaro. (2017) Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53. Journal of Experimental & Clinical Cancer Research 36:1.
Crossref
Crossref
Mika Hosokawa, Shota Tanaka, Kumiko Ueda & Seigo Iwakawa. (2017) Different Schedule-Dependent Effects of Epigenetic Modifiers on Cytotoxicity by Anticancer Drugs in Colorectal Cancer Cells. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 40:12, pages 2199-2204.
Crossref
Crossref
Kristelle Desfossés-Baron, Ian Hammond-Martel, Antoine Simoneau, Adnane Sellam, Stephen Roberts & Hugo Wurtele. (2016) Valproate inhibits MAP kinase signalling and cell cycle progression in S. cerevisiae. Scientific Reports 6:1.
Crossref
Crossref
Gilles Huberfeld & Charles J. Vecht. (2016) Seizures and gliomas — towards a single therapeutic approach. Nature Reviews Neurology 12:4, pages 204-216.
Crossref
Crossref
Takeo Kubota, Kunio Miyake, Natsuyo Hariya, Vuong Tran Nguyen Quoc & Kazuki Mochizuki. (2016) Prader-Willi Syndrome: The Disease that Opened up Epigenomic-Based Preemptive Medicine. Diseases 4:1, pages 15.
Crossref
Crossref
Torbj?rn Tomson, Dina Battino & Emilio Perucca. (2016) Valproic acid after five decades of use in epilepsy: time to reconsider the indications of a time-honoured drug. The Lancet Neurology 15:2, pages 210-218.
Crossref
Crossref
Yvonne Arvidsson, Viktor Johanson, Roswitha Pfragner, Bo Wängberg & Ola Nilsson. (2016) Cytotoxic Effects of Valproic Acid on Neuroendocrine Tumour Cells. Neuroendocrinology 103:5, pages 578-591.
Crossref
Crossref
M. Dvorakova & T. Vanek. (2016) Histone deacetylase inhibitors for the treatment of cancer stem cells. MedChemComm 7:12, pages 2217-2231.
Crossref
Crossref
Chen-Hsun Ho, Jui-Ling Hsu, Shih-Ping Liu, Lih-Ching Hsu, Wei-Ling Chang, Chuck C.-K. Chao & Jih-Hwa Guh. (2015) Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway. The Prostate 75:13, pages 1454-1466.
Crossref
Crossref
Beidi Lan, Emiko Hayama, Nanako Kawaguchi, Yoshiyuki Furutani & Toshio Nakanishi. (2015) Therapeutic Efficacy of Valproic Acid in a Combined Monocrotaline and Chronic Hypoxia Rat Model of Severe Pulmonary Hypertension. PLOS ONE 10:1, pages e0117211.
Crossref
Crossref
Peter Ranger & Bart A. Ellenbroek. 2016. Neurotoxin Modeling of Brain Disorders—Life-long Outcomes in Behavioral Teratology. Neurotoxin Modeling of Brain Disorders—Life-long Outcomes in Behavioral Teratology
363
386
.