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Expert Review of Molecular Diagnostics Volume 14, 2014 - Issue 5
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microRNAs in the tumor microenvironment: solving the riddle for a better diagnostics

Kishore B ChallagundlaDepartments of Pediatrics and Molecular Microbiology & Immunology, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Saban Research Institute, Children’s Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles, Los Angeles, CA, USA
,
Francesca FaniniIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) S.r.l. IRCCS, Unit of Gene Therapy, Meldola (FC) 47014, Italy
,
Ivan VanniniIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) S.r.l. IRCCS, Unit of Gene Therapy, Meldola (FC) 47014, Italy
,
Petra WiseDepartments of Pediatrics and Molecular Microbiology & Immunology, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Saban Research Institute, Children’s Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles, Los Angeles, CA, USA
,
Mariam MurtadhaDepartments of Pediatrics and Molecular Microbiology & Immunology, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Saban Research Institute, Children’s Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles, Los Angeles, CA, USA
,
Lawrence MalinconicoDepartments of Pediatrics and Molecular Microbiology & Immunology, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Saban Research Institute, Children’s Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles, Los Angeles, CA, USA
,
Amelia CimminoInstitute of Genetics and Biophysics, National Research Council and Fondazione IRCCS SDN, Naples (NA) 80131, Italy
&
Muller FabbriDepartments of Pediatrics and Molecular Microbiology & Immunology, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Saban Research Institute, Children’s Center for Cancer and Blood Diseases, Children’s Hospital Los Angeles, Los Angeles, CA, USACorrespondence[email protected]
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Pages 565-574 | Published online: 21 May 2014

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Shuo Wang, Yongxiang Yang, Lili Sun, Guoliang Qiao, Yunlong Song & Bing Liu. (2020) Exosomal MicroRNAs as Liquid Biopsy Biomarkers in Hepatocellular Carcinoma. OncoTargets and Therapy 13, pages 2021-2030.
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WeiHong Ren, XuRan Zhang, WenBo Li, Qian Feng, HuiJie Feng, Yan Tong, Hao Rong, Wei Wang, Dai Zhang, ZhenQiang Zhang, ShiChun Tu, XiaoYan Zhu & QinXian Zhang. (2019) Exosomal miRNA-107 induces myeloid-derived suppressor cell expansion in gastric cancer. Cancer Management and Research 11, pages 4023-4040.
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Li Min, Shengtao Zhu, Lei Chen, Xiang Liu, Rui Wei, Libo Zhao, Yuqing Yang, Zheng Zhang, Guanyi Kong, Peng Li & Shutian Zhang. (2019) Evaluation of circulating small extracellular vesicles derived miRNAs as biomarkers of early colon cancer: a comparison with plasma total miRNAs. Journal of Extracellular Vesicles 8:1.
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Diana Gulei, Bogdan Petrut, Adrian Bogdan Tigu, Anca Onaciu, Eva Fischer-Fodor, Atanas G. Atanasov, Calin Ionescu & Ioana Berindan-Neagoe. (2018) Exosomes at a glance – common nominators for cancer hallmarks and novel diagnosis tools. Critical Reviews in Biochemistry and Molecular Biology 53:5, pages 564-577.
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Leonie Mühlberg, Benjamin Kühnemuth, Eithne Costello, Victoria Shaw, Bence Sipos, Magdalena Huber, Heidi Griesmann, Sebastian Krug, Marvin Schober, Thomas M. Gress & Patrick Michl. (2016) miRNA dynamics in tumor-infiltrating myeloid cells modulating tumor progression in pancreatic cancer. OncoImmunology 5:6.
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Heidi Schwarzenbach. (2015) The clinical relevance of circulating, exosomal miRNAs as biomarkers for cancer. Expert Review of Molecular Diagnostics 15:9, pages 1159-1169.
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Prasun J Mishra. (2014) Non-coding RNAs as clinical biomarkers for cancer diagnosis and prognosis. Expert Review of Molecular Diagnostics 14:8, pages 917-919.
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Qi Xiao, Xiaoqian Yan, Yu Sun, Yuru Tang, Rongyao Hou, Xudong Pan & Xiaoyan Zhu. (2023) Brain-Derived Exosomal miRNA Profiles upon Experimental SAE Rats and Their Comparison with Peripheral Exosomes. Molecular Neurobiology.
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Ali Seyed Salehi, Negar Parsa-Nikoo, Farnaz Roshan-Farzad, Roshanak Shams, Mohadeseh Fathi, Hamid Asaszadeh Aghdaei & Ali Behmanesh. (2022) MicroRNA-125a-3p, -4530, and -92a as a Potential Circulating MicroRNA Panel for Noninvasive Pancreatic Cancer Diagnosis. Disease Markers 2022, pages 1-9.
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Jingwen Yang, Weiwei Dong, He Zhang, Huixia Zhao, Zhiyan Zeng, Fengyun Zhang, Qiuwen Li, Xiaohong Duan, Yanyan Hu & Wenhua Xiao. (2022) Exosomal microRNA panel as a diagnostic biomarker in patients with hepatocellular carcinoma. Frontiers in Cell and Developmental Biology 10.
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Petra M. Wise, Paolo Neviani, Stefan Riwaldt, Thomas J. Corydon, Markus Wehland, Markus Braun, Marcus Krüger, Manfred Infanger & Daniela Grimm. (2021) Changes in Exosomal miRNA Composition in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space. International Journal of Molecular Sciences 22:23, pages 12841.
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Petra M. Wise, Paolo Neviani, Stefan Riwaldt, Thomas Juhl Corydon, Markus Wehland, Markus Braun, Marcus Krüger, Manfred Infanger & Daniela Grimm. (2021) Changes in Exosome Release in Thyroid Cancer Cells after Prolonged Exposure to Real Microgravity in Space. International Journal of Molecular Sciences 22:4, pages 2132.
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Vandit Shah & Jigna Shah. (2020) Recent trends in targeting miRNAs for cancer therapy. Journal of Pharmacy and Pharmacology 72:12, pages 1732-1749.
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Amit Kumar Mitra, Harish Kumar, Vijay Ramakrishnan, Li Chen, Linda Baughn, Shaji Kumar, S. Vincent Rajkumar & Brian G. Van Ness. (2020) In vitro and ex vivo gene expression profiling reveals differential kinetic response of HSPs and UPR genes is associated with PI resistance in multiple myeloma. Blood Cancer Journal 10:7.
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Beatrice Aramini, Valentina Masciale & Khawaja Husnain Haider. (2020) Defining lung cancer stem cells exosomal payload of miRNAs in clinical perspective. World Journal of Stem Cells 12:6, pages 406-421.
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Nahian Binte Aziz, Rabbee G. Mahmudunnabi, Muhammad Umer, Shayna Sharma, Md Abdur Rashid, Yahya Alhamhoom, Yoon-Bo Shim, Carlos Salomon & Muhammad J. A. Shiddiky. (2020) MicroRNAs in ovarian cancer and recent advances in the development of microRNA-based biosensors. The Analyst 145:6, pages 2038-2057.
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