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Review

CSF biomarkers for Alzheimer’s disease: use in early diagnosis and evaluation of drug treatment

Pages 661-672 | Published online: 09 Jan 2014

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Hayrettin Tumani, Charlotte Teunissen, Sigurd Süssmuth, Markus Otto, Albert C Ludolph & Johannes Brettschneider. (2008) Cerebrospinal fluid biomarkers of neurodegeneration in chronic neurological diseases. Expert Review of Molecular Diagnostics 8:4, pages 479-494.
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Erik Portelius, Henrik Zetterberg, Johan Gobom, Ulf Andreasson & Kaj Blennow. (2008) Targeted proteomics in Alzheimer’s disease: focus on amyloid-β. Expert Review of Proteomics 5:2, pages 225-237.
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Hanno M Roder & Michael L Hutton. (2007) Microtubule-associated protein tau as a therapeutic target in neurodegenerative disease. Expert Opinion on Therapeutic Targets 11:4, pages 435-442.
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Robert Bowser, Merit Cudkowicz & Rima Kaddurah-Daouk. (2006) Biomarkers for amyotrophic lateral sclerosis. Expert Review of Molecular Diagnostics 6:3, pages 387-398.
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Oliver Schmidt, Thomas Schulenborg, Helmut E Meyer, Katrin Marcus & Michael Hamacher. (2005) How proteomics reveals potential biomarkers in brain diseases. Expert Review of Proteomics 2:6, pages 901-913.
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Articles from other publishers (83)

Christine Zürcher & Christian Humpel. (2023) Saliva: a challenging human fluid to diagnose brain disorders with a focus on Alzheimer’s disease. Neural Regeneration Research 18:12, pages 2606-2610.
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Binita Rajbanshi, Anuj Guruacharya, James W. Mandell & George S. Bloom. (2023) Localization, induction, and cellular effects of tau phosphorylated at threonine 217 1 . Alzheimer's & Dementia 19:7, pages 2874-2887.
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Josef Marksteiner, Michaela Defrancesco & Christian Humpel. (2022) Saliva tau and phospho-tau-181 measured by Lumipulse in patients with Alzheimer’s disease. Frontiers in Aging Neuroscience 14.
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Leming Sun, Yang Lei, Yuerong Wang & Dingchang Liu. (2022) Blood-based Alzheimer's disease diagnosis using fluorescent peptide nanoparticle arrays. Chinese Chemical Letters 33:4, pages 1946-1950.
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Dhwani S. Korde & Christian Humpel. (2022) Western Agarose Native GeELution (WANGEL) with beta-amyloid and tau: Novel method to elute proteins or peptides using native agarose gels followed by Lumipulse assay. MethodsX 9, pages 101779.
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Michelle M. Nuño & Daniel L. Gillen. (2021) Censoring‐robust time‐dependent receiver operating characteristic curve estimators. Statistics in Medicine 40:30, pages 6885-6899.
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Lei Feng, Jinming Li & Rui Zhang. (2021) Current research status of blood biomarkers in Alzheimer’s disease: Diagnosis and prognosis. Ageing Research Reviews 72, pages 101492.
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Vincent Marcucci & Jeremy Kleiman. (2021) Biomarkers and Their Implications in Alzheimer’s Disease: A Literature Review. Exploratory Research and Hypothesis in Medicine 000:000, pages 000-000.
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Imrich Blasko, Michaela Defrancesco, Herbert Oberacher, Lorin Loacker, Georg Kemmler, Josef Marksteiner & Christian Humpel. (2021) Plasma phosphatidylcholines and vitamin B12/folate levels are possible prognostic biomarkers for progression of Alzheimer's disease. Experimental Gerontology 147, pages 111264.
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Yiyun Jin, Devkee Mahesh Vadukul, Dimitra Gialama, Ying Ge, Rebecca Thrush, Joe Thomas White & Francesco Antonio Aprile. (2021) The Diagnostic Potential of Amyloidogenic Proteins. International Journal of Molecular Sciences 22:8, pages 4128.
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Ram Sagar, Pujita Pathak, Balint Pandur, Sujung Jun Kim, Jiaxin Li & Vasiliki Mahairaki. 2021. GeNeDis 2020. GeNeDis 2020 403 408 .
Jozef HanesAndrej KovacHlin KvartsbergEva KontsekovaLubica FialovaStanislav Katina, Branislav KovacechEva StevensJakub HortMartin VyhnalekLynn BoonkampMichal NovakHenrik ZetterbergOskar HanssonPhilip Scheltens, Kaj BlennowCharlotte E. TeunissenNorbert Zilka. (2020) Evaluation of a novel immunoassay to detect p-tau Thr217 in the CSF to distinguish Alzheimer disease from other dementias. Neurology 95:22.
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Md. Sahab Uddin, Md. Tanvir Kabir, Md. Sohanur Rahman, Tapan Behl, Philippe Jeandet, Ghulam Md Ashraf, Agnieszka Najda, May N. Bin-Jumah, Hesham R. El-Seedi & Mohamed M. Abdel-Daim. (2020) Revisiting the Amyloid Cascade Hypothesis: From Anti-Aβ Therapeutics to Auspicious New Ways for Alzheimer’s Disease. International Journal of Molecular Sciences 21:16, pages 5858.
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Shahul Hameed, Jong-Ling Fuh, Vorapun Senanarong, Esther Gunaseli M. Ebenezer, Irene Looi, Jacqueline C. Dominguez, Kyung Won Park, Ananda Krishna Karanam & Oliver Simon. (2020) Role of Fluid Biomarkers and PET Imaging in Early Diagnosis and its Clinical Implication in the Management of Alzheimer’s Disease. Journal of Alzheimer's Disease Reports 4:1, pages 21-37.
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Wei-Chieh Weng, Wen-Yi Huang, Hsiang-Yu Tang, Mei-Ling Cheng & Kuan-Hsing Chen. (2019) The Differences of Serum Metabolites Between Patients With Early-Stage Alzheimer's Disease and Mild Cognitive Impairment. Frontiers in Neurology 10.
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M.A. Arya, Maneesha K. Manoj Kumar, M. Sabitha, Krishnakumar N. Menon & Sreeja C. Nair. (2019) Nanotechnology approaches for enhanced CNS delivery in treating Alzheimer's disease. Journal of Drug Delivery Science and Technology 51, pages 297-309.
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Josef Marksteiner, Herbert Oberacher & Christian Humpel. (2019) Acyl-Alkyl-Phosphatidlycholines are Decreased in Saliva of Patients with Alzheimer’s Disease as Identified by Targeted Metabolomics. Journal of Alzheimer's Disease 68:2, pages 583-589.
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Maria Dantas Costa Lima Godoy, Marco Aurélio Fornazieri, Richard L. Doty, Fábio de Rezende Pinna, José Marcelo Farfel, Glaucia Bento dos Santos, Mariana Molina, Renata E. L. Ferretti-Rebustini, Renata E. P. Leite, Claudia K. Suemoto, Lea T. Grinberg, Carlos A. G. Pasqualucci, Richard Louis Voegels, Ricardo Nitrini & Wilson Jacob Filho. (2018) Is Olfactory Epithelium Biopsy Useful for Confirming Alzheimer’s Disease?. Annals of Otology, Rhinology & Laryngology 128:3, pages 184-192.
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Josef Marksteiner, Imrich Blasko, Georg Kemmler, Therese Koal & Christian Humpel. (2017) Bile acid quantification of 20 plasma metabolites identifies lithocholic acid as a putative biomarker in Alzheimer’s disease. Metabolomics 14:1.
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Tao Yue, Xinghua Jia, Jennifer PetrosinoLeming SunZhen FanJesse FineRebecca Davis, Scott Galster, Jeff Kuret, Douglas W. Scharre & Mingjun Zhang. (2017) Computational integration of nanoscale physical biomarkers and cognitive assessments for Alzheimer’s disease diagnosis and prognosis. Science Advances 3:7.
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