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The rise and fall of felbamate as a treatment for partial epilepsy – aplastic anemia and hepatic failure to blame?

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Debopam Samanta. (2022) Pharmacotherapeutic management of seizures in patients with Angleman Syndrome. Expert Opinion on Pharmacotherapy 23:13, pages 1511-1522.
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Alberto Verrotti, Giulia Iapadre, Giulia Di Donato, Ludovica Di Francesco, Luca Zagaroli, Sara Matricardi, Vincenzo Belcastro & Maria Laura Iezzi. (2019) Pharmacokinetic considerations for anti-epileptic drugs in children. Expert Opinion on Drug Metabolism & Toxicology 15:3, pages 199-211.
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David Bibi, Bella Shusterman, Alessio Nocentini, Claudiu T. Supuran & Meir Bialer. (2019) Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivative. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 1078-1082.
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Articles from other publishers (13)

Yash Pal Singh, Navneet Kumar, Brijesh Singh Chauhan & Prabha Garg. (2023) Carbamate as a potential anti‐Alzheimer's pharmacophore: A review. Drug Development Research.
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Becky J. Wong, Rita Agarwal & Michael I. Chen. (2021) Anesthesia for the Pediatric Patient With Epilepsy and Minimally Invasive Surgery for Epilepsy. Current Anesthesiology Reports 11:3, pages 233-242.
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Albert P. Li. 2021. Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity. Transporters and Drug‐Metabolizing Enzymes in Drug Toxicity 41 77 .
Reem Odi, David Bibi, Bella Shusterman, Natalia Erenburg, Chanan Shaul, Claudiu T. Supuran, Alessio Nocentini & Meir Bialer. (2021) Synthesis and Enantioselective Pharmacokinetic/Pharmacodynamic Analysis of New CNS-Active Sulfamoylphenyl Carbamate Derivatives. International Journal of Molecular Sciences 22:7, pages 3361.
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Wolfgang Löscher, Graeme J. Sills & H. Steve White. (2021) The ups and downs of alkyl‐carbamates in epilepsy therapy: How does cenobamate differ?. Epilepsia 62:3, pages 596-614.
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Li Di, Amanda Balesano, Samantha Jordan & Sophia M. Shi. (2021) The Role of Alcohol Dehydrogenase in Drug Metabolism: Beyond Ethanol Oxidation. The AAPS Journal 23:1.
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Adam Strzelczyk & Susanne Schubert-Bast. (2021) Expanding the Treatment Landscape for Lennox-Gastaut Syndrome: Current and Future Strategies. CNS Drugs 35:1, pages 61-83.
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Christopher T. Buckley, Olivia R. Waters & George DeMaagd. (2020) Cenobamate: A New Adjunctive Agent for Drug-Resistant Focal Onset Epilepsy. Annals of Pharmacotherapy, pages 106002802094111.
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Yashmay Gordhon & Neelaveni Padayachee. (2020) Evaluating the knowledge, attitudes and practices of healthcare workers towards adverse drug reaction reporting at a public tertiary hospital in Johannesburg. International Journal of Africa Nursing Sciences 12, pages 100191.
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Xiuqin Li, Hongze Wang, Qingnian Chen, Zhiqin Li, Chao Liu, Shengnan Yin & Zhengchen You. (2019) Felbamate produces antidepressant‐like actions in the chronic unpredictable mild stress and chronic social defeat stress models of depression. Fundamental & Clinical Pharmacology 33:6, pages 621-633.
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Sara Hocker. 2018. Status Epilepticus. Status Epilepticus 201 214 .
Charlotte S. Kwok, Emily L. Johnson & Gregory L. Krauss. (2017) Comparing Safety and Efficacy of “Third-Generation” Antiepileptic Drugs: Long-Term Extension and Post-marketing Treatment. CNS Drugs 31:11, pages 959-974.
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Hafiz Mawasi, David Bibi & Meir Bialer. (2016) Design and comparative anticonvulsant activity assessment of CNS-active alkyl-carbamoyl imidazole derivatives. Bioorganic & Medicinal Chemistry 24:18, pages 4246-4253.
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