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Expert Review of Neurotherapeutics Volume 8, 2008 - Issue 11
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Drug Profile

Dexketoprofen trometamol: clinical evidence supporting its role as a painkiller

Manuel J Barbanoj Rodríguez Centre d’Investigació del Medicament, Institut de Recerca; Clinical Pharmacology Service, Hospital de la Santa Creu i Sant Pau; Department of Pharmacology and Therapeutics, Autonomous University of Barcelona, Spain; CIM - Sant Pau, Hospital de la Santa Creu i Sant Pau, Av. Sant Antoni M. Claret 167, 08025, Barcelona, Spain. [email protected]
,
Rosa M Antonijoan Arbós Centre d’Investigació del Medicament, Institut de Recerca; Clinical Pharmacology Service, Hospital de la Santa Creu i Sant Pau; Department of Pharmacology and Therapeutics, Autonomous University of Barcelona, Spain
&
Salvador Rico Amaro Centre d’Investigació del Medicament, Institut de Recerca; Clinical Pharmacology Service, Hospital de la Santa Creu i Sant Pau; Department of Pharmacology and Therapeutics, Autonomous University of Barcelona, Spain
Pages 1625-1640 | Published online: 09 Jan 2014

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Aras Erdil, Mustafa Sami Demirsoy, Sefa Çolak, Esra Duman, Orhan Sümbül & Hatice Aygun. (2021) The effect of dexketoprofen trometamol on WAG/Rij rats with absence epilepsy (dexketoprofen in absence epilepsy). Neurological Research 43:12, pages 1116-1125.
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Magdi Hanna & Jee Y. Moon. (2019) A review of dexketoprofen trometamol in acute pain. Current Medical Research and Opinion 35:2, pages 189-202.
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Giustino Varrassi, Magdi Hanna, Giorgos Macheras, Antonio Montero, Antonio Montes Perez, Winfried Meissner, Serge Perrot & Carmelo Scarpignato. (2017) Multimodal analgesia in moderate-to-severe pain: a role for a new fixed combination of dexketoprofen and tramadol. Current Medical Research and Opinion 33:6, pages 1165-1173.
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Articles from other publishers (21)

Naime Yalçın, Ayça S. Şahin, Barış Sandal, Abdurrahim Derbent & Ziya Salihoğlu. (2022) The impact of intravenously administered dexketoprofen trometamol on analgesia and recovery in ambulatory dilatation and curettage procedures: a retrospective analysis. Ain-Shams Journal of Anesthesiology 14:1.
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Ersin Koksal, Yasemin Burcu Ustun, Sezgin Bilgin, Abdurrahman Aksoy, Yavuz Kursad Das, Murat Yarim, Fatih Ozkan, Cengiz Kaya & Burhan Dost. (2022) The effects of dexketoprofen on renal ischemia-reperfusion injury: an experimental study. Brazilian Journal of Anesthesiology (English Edition) 72:3, pages 365-371.
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I.I. Delva. (2022) Синдром Персонейджа — Тернера: принципи діагностики й лікування. INTERNATIONAL NEUROLOGICAL JOURNAL 17:8, pages 39-44.
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Sultan Tuna Akgol Gur, Elif Oral Ahiskalioglu, Muhammed Enes Aydin, Abdullah Osman Kocak, Pelin Aydin & Ali Ahiskalioglu. (2021) Intravenous lidocaine vs. NSAIDs for migraine attack in the ED: a prospective, randomized, double-blind study. European Journal of Clinical Pharmacology 78:1, pages 27-33.
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Mustafa Sami Demirsoy, Aras Erdil, Sefa Çolak, Esra Duman, Orhan Sümbül & Hatice Aygun. (2021) Acute treatment with dexketoprofen reduces penicillin induced epileptiform activity in wistar albino rats (dexketoprofen in penicillin induced seizure model). Epilepsy Research 178, pages 106827.
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Juan Carlos Flores-Arriaga, Daniel Chavarría-Bolaños, Amaury de Jesús Pozos-Guillén, Vladimir Alonso Escobar-Barrios & Bernardino Isaac Cerda-Cristerna. (2021) Synthesis of a PVA drug delivery system for controlled release of a Tramadol–Dexketoprofen combination. Journal of Materials Science: Materials in Medicine 32:5.
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Liliana Mititelu-Tartau, Maria Bogdan, Daniela Angelica Pricop, Beatrice Rozalina Buca, Loredana Hilitanu, Ana-Maria Pauna, Lorena Anda Dijmarescu & Eliza Gratiela Popa. (2021) Biocompatibility and Pharmacological Effects of Innovative Systems for Prolonged Drug Release Containing Dexketoprofen in Rats. Polymers 13:7, pages 1010.
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Antonella Paladini & Giustino Varrassi. 2021. Pain Management - Practices, Novel Therapies and Bioactives. Pain Management - Practices, Novel Therapies and Bioactives.
M. G. Melnik. (2021) Choice of optimal non-steroidal anti-inflammatory drug from position of cardiologist. Medical alphabet:36, pages 55-60.
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M. V. Pchelintsev. (2020) Pain syndrome in oncology. Possibilities of dexketoprofen administration. Meditsinskiy sovet = Medical Council:9, pages 146-154.
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Cengiz Kaya, Yunus O. Atalay, Bilge C. Meydan, Yasemin B. Ustun, Ersin Koksal & Sultan Caliskan. (2019) Evaluation of the neurotoxic effects of intrathecal administration of (S)-(+)-Ketoprofen on rat spinal cords: randomized controlled experimental study. Brazilian Journal of Anesthesiology (English Edition) 69:4, pages 403-412.
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Cengiz Kaya, Yunus O. Atalay, Bilge C. Meydan, Yasemin B. Ustun, Ersin Koksal & Sultan Caliskan. (2019) Avaliação dos efeitos neurotóxicos da administração intratecal do (S)‐(+)‐cetoprofeno em medula espinhal de rato: estudo experimental randômico e controlado. Brazilian Journal of Anesthesiology 69:4, pages 403-412.
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Lidija Bach-Rojecky, Dalia Vađunec, Katarina Žunić, Jelena Kurija, Sara Šipicki, Ryan Gregg, Ivan Mikula & Dragan Primorac. (2019) Continuing war on pain: a personalized approach to the therapy with nonsteroidal anti-inflammatory drugs and opioids. Personalized Medicine 16:2, pages 171-184.
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Vicente Esparza-Villalpando, Daniel Chavarria-Bolaños, Juan Ramón Zapata-Morales, Antonio Vértiz-Hernández & Amaury Pozos-Guillén. (2018) Antinociceptive local effect of the combination of dexketoprofen trometamol and chlorhexidine gluconate in a formalin test: an additive effect. Brazilian Journal of Pharmaceutical Sciences 54:2.
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Vicente Esparza-Villalpando, Amaury Pozos-Guillén, David Masuoka-Ito, César Gaitán-Fonseca & Daniel Chavarría-Bolaños. (2018) Analgesic efficacy of preoperative dexketoprofen trometamol: A systematic review and meta-analysis. Drug Development Research 79:2, pages 47-57.
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R. A. Moore, H. J. McQuay, J. Tomaszewski, G. Raba, D. Tutunaru, N. Lietuviete, J. Galad, L. Hagymasy, D. Melka, J. Kotarski, T. Rechberger, B. Fülesdi, A. Nizzardo, C. Guerrero-Bayón, S. Cuadripani, B. Pizà-Vallespir & M. Bertolotti. (2016) Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate-to-severe acute pain after abdominal hysterectomy. BMC Anesthesiology 16:1.
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Vicente Esparza-Villalpando, Daniel Chavarria-Bolaños, Antonio Gordillo-Moscoso, David Masuoka-Ito, Ricardo Martinez-Rider, Mario Isiordia-Espinoza & Amaury Pozos-Guillen. (2016) Comparison of the analgesic efficacy of preoperative/postoperative oral dexketoprofen trometamol in third molar surgery: A randomized clinical trial. Journal of Cranio-Maxillofacial Surgery 44:9, pages 1350-1355.
Crossref
Vera Parkhutik, Aida Lago, Jose Ignacio Tembl, Concepcion Rubio, Maria Paz Fuset, Juana Vallés, Maria Teresa Santos & Antonio Moscardo. (2012) Influence of COX-inhibiting Analgesics on the Platelet Function of Patients with Subarachnoid Hemorrhage. Journal of Stroke and Cerebrovascular Diseases 21:8, pages 755-759.
Crossref
A. Porwal, A. D. Mahajan, D. S. Oswal, S. S. Erram, D. N. Sheth, S. Balamurugan, V. Kamat, R. P. Enadle, A. Badadare, S. K. Bhatnagar, R. S. Walvekar, S. Dhorepatil, R. C. Naik, I. Basu, S. N. Kshirsagar, J. V. Keny & S. Sengupta. (2012) Efficacy and Tolerability of Fixed-Dose Combination of Dexketoprofen and Dicyclomine Injection in Acute Renal Colic. Pain Research and Treatment 2012, pages 1-5.
Crossref
Jean-Sébastien Walczak. (2011) Analgesic properties of dexketoprofen trometamol. Pain Management 1:5, pages 409-416.
Crossref
P. T. Jamdade, A. Porwal, J. V. Shinde, S. S. Erram, V. V. Kamat, P. S. Karmarkar, K. Bhagtani, S. Dhorepatil, R. Irpatgire, H. Bhagat, S. S. Kolte & P. A. Shirure. (2011) Efficacy and Tolerability of Intramuscular Dexketoprofen in Postoperative Pain Management following Hernia Repair Surgery. Anesthesiology Research and Practice 2011, pages 1-4.
Crossref

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