Citations (67)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (4)
Keven Lothert, Friederike Eilts & Michael W. Wolff. (2022) Quantification methods for viruses and virus-like particles applied in biopharmaceutical production processes. Expert Review of Vaccines 21:8, pages 1029-1044.
Read now
Read now
Qu-Lai Tang, Li-Xing Gu, Yao Xu, Xing-Hua Liao, Yong Zhou & Tong-Cun Zhang. (2021) Establishing functional lentiviral vector production in a stirred bioreactor for CAR-T cell therapy. Bioengineered 12:1, pages 2095-2105.
Read now
Read now
Andrew Yongky, Jianlin Xu, Jun Tian, Christopher Oliveira, Jia Zhao, Kevin McFarland, Michael C. Borys & Zheng Jian Li. (2019) Process intensification in fed-batch production bioreactors using non-perfusion seed cultures. mAbs 11:8, pages 1502-1514.
Read now
Read now
M. Farzaneh, F. Attari, P. E. Mozdziak & S. E. Khoshnam. (2017) The evolution of chicken stem cell culture methods. British Poultry Science 58:6, pages 681-686.
Read now
Read now
Articles from other publishers (63)
Geng Liu, Mengyuan Pei, Siya Wang, Zhenyu Qiu, Xiaoyun Li, Hua Ma, Yumei Ma, Jiamin Wang, Zilin Qiao, Zhongren Ma & Zhenbin Liu. (2023) Transcriptional Analysis of lncRNA and Target Genes Induced by Influenza A Virus Infection in MDCK Cells. Vaccines 11:10, pages 1593.
Crossref
Crossref
Chang Ge, P. Ravi Selvaganapathy & Fei Geng. (2023) Advancing our understanding of bioreactors for industrial-sized cell culture: health care and cellular agriculture implications. American Journal of Physiology-Cell Physiology 325:3, pages C580-C591.
Crossref
Crossref
Sven Göbel, Karim E. Jaén, Marie Dorn, Victoria Neumeyer, Ingo Jordan, Volker Sandig, Udo Reichl, Jennifer Altomonte & Yvonne Genzel. (2023) Process intensification strategies toward cell culture‐based high‐yield production of a fusogenic oncolytic virus. Biotechnology and Bioengineering 120:9, pages 2639-2657.
Crossref
Crossref
Marc D. Hein, Daniel Kazenmaier, Yasemin van Heuvel, Tanya Dogra, Maurizio Cattaneo, Sascha Y. Kupke, Jörn Stitz, Yvonne Genzel & Udo Reichl. (2023) Production of retroviral vectors in continuous high cell density culture. Applied Microbiology and Biotechnology.
Crossref
Crossref
Hwi-Yeon Choi, Jong-Chul Choi, Yeong-Lim Kang, So-Hyeun Ahn, Sang-Won Lee, Seung-Yong Park, Chang-Seon Song, In-Soo Choi & Joong-Bok Lee. (2023) Production of a chimeric porcine reproductive and respiratory syndrome virus (PRRSV)-2 vaccine using a lab-scale packed-bed bioreactor CelCradle. BMC Veterinary Research 19:1.
Crossref
Crossref
Jinhu Li, Yurou Wu, Xiang Yao, Yao Tian, Xue Sun, Zibo Liu, Xun Ye & Chunjie Wu. (2023) Preclinical Research of Stem Cells: Challenges and Progress. Stem Cell Reviews and Reports 19:6, pages 1676-1690.
Crossref
Crossref
Elaine Meade, Neil Rowan & Mary Garvey. (2023) Bioprocessing and the Production of Antiviral Biologics in the Prevention and Treatment of Viral Infectious Disease. Vaccines 11:5, pages 992.
Crossref
Crossref
Muhammad Waqar Aziz, Nadia Mukhtar, Aftab Ahamd Anjum, Muhammad Hassan Mushtaq, Muhammad Furqan Shahid, Muzaffar Ali, Muhammad Abu Bakr Shabbir, Muhammad Asad Ali, Muhammad Nawaz & Tahir Yaqub. (2023) Molecular Characterization and Selection of Indigenous SARS-CoV-2 Delta Variant for the Development of the First Inactivated SARS-CoV-2 Vaccine of Pakistan. Vaccines 11:3, pages 607.
Crossref
Crossref
Christopher Ton, Victoria Stabile, Elizabeth Carey, Adam Maraikar, Travis Whitmer, Samantha Marrone, Nelson Lee Afanador, Igor Zabrodin, Greeshma Manomohan, Melissa Whiteman & Carl Hofmann. (2023) Development and scale-up of rVSV-SARS-CoV-2 vaccine process using single use bioreactor. Biotechnology Reports 37, pages e00782.
Crossref
Crossref
Christopher T. Canova, Pavan K. Inguva & Richard D. Braatz. (2022) Mechanistic modeling of viral particle production. Biotechnology and Bioengineering 120:3, pages 629-641.
Crossref
Crossref
Wilson Lewis Mandala. 2023. COVID-19 Vaccines - Current State and Perspectives. COVID-19 Vaccines - Current State and Perspectives.
Orsolya Hamusics & Daniel Loewe. 2023. Bioprocess and Analytics Development for Virus-based Advanced Therapeutics and Medicinal Products (ATMPs). Bioprocess and Analytics Development for Virus-based Advanced Therapeutics and Medicinal Products (ATMPs)
49
72
.
María Susana Pérez-Grisales & Sandra I. Uribe Soto. (2022) Insects as sources of food and bioproducts: a review from Colombia. The Journal of Basic and Applied Zoology 83:1.
Crossref
Crossref
S. Furkan Demirden, Kadir Alptekin, Ilgin Kimiz-Gebologlu & Suphi S. Oncel. (2022) Influenza Vaccine: An Engineering Vision from Virological Importance to Production. Biotechnology and Bioprocess Engineering 27:5, pages 740-764.
Crossref
Crossref
Manya Mittal, Manidipa Banerjee, Linda HL Lua & Anurag S Rathore. (2021) Current status and future challenges in transitioning to continuous bioprocessing of virus‐like particles. Journal of Chemical Technology & Biotechnology 97:9, pages 2376-2385.
Crossref
Crossref
Zhongbiao Fang, Jingting Lyu, Jianhua Li, Chaonan Li, Yuxuan Zhang, Yikai Guo, Ying Wang, Yanjun Zhang & Keda Chen. (2022) Application of bioreactor technology for cell culture-based viral vaccine production: Present status and future prospects. Frontiers in Bioengineering and Biotechnology 10.
Crossref
Crossref
Sven Göbel, Fabian Kortum, Karim Jaén Chavez, Ingo Jordan, Volker Sandig, Udo Reichl, Jennifer Altomonte & Yvonne Genzel. (2022) Cell-line screening and process development for a fusogenic oncolytic virus in small-scale suspension cultures. Applied Microbiology and Biotechnology 106:13-16, pages 4945-4961.
Crossref
Crossref
Bruno M. Ladeira, Catarina A. Custódio & João F. Mano. (2022) Core–shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine. Biomaterials Science 10:9, pages 2122-2153.
Crossref
Crossref
Jan Küchler, Sebastian Püttker, Patrick Lahmann, Yvonne Genzel, Sascha Kupke, Dirk Benndorf & Udo Reichl. (2022) Absolute quantification of viral proteins during single-round replication of MDCK suspension cells. Journal of Proteomics 259, pages 104544.
Crossref
Crossref
Rudra Prasad Roy & Laxmi Devi. (2022) Strategy construction to minimize the limitation of respiratory viral vaccine development. Indian Journal of Microbiology Research 9:1, pages 1-8.
Crossref
Crossref
Jonas B. Sandbrink & Gregory D. Koblentz. (2022) Biosecurity risks associated with vaccine platform technologies. Vaccine 40:17, pages 2514-2523.
Crossref
Crossref
Mateusz Bartczak, Kamil Wierzchowski & Maciej Pilarek. (2022) Mixing performance in a litre-scale rocking disposable bioreactor: DoE-based investigation of mixing time dependence on operational parameters. Chemical Engineering Journal 431, pages 133288.
Crossref
Crossref
Ivana Pajčin, Teodora Knežić, Ivana Savic Azoulay, Vanja Vlajkov, Mila Djisalov, Ljiljana Janjušević, Jovana Grahovac & Ivana Gadjanski. (2022) Bioengineering Outlook on Cultivated Meat Production. Micromachines 13:3, pages 402.
Crossref
Crossref
Rajesh Sharma, Susan T. L. Harrison & Siew Leng Tai. (2021) Advances in Bioreactor Systems for the Production of Biologicals in Mammalian Cells. ChemBioEng Reviews 9:1, pages 42-62.
Crossref
Crossref
Thomas Bissinger, Yixiao Wu, Pavel Marichal‐Gallardo, Dietmar Riedel, Xuping Liu, Yvonne Genzel, Wen‐Song Tan & Udo Reichl. (2021) Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells. Biotechnology and Bioengineering 118:10, pages 3996-4013.
Crossref
Crossref
A.‐Y. Kim, H. Kim, S.Y. Park, S.H. Park, J.‐M. Lee, J.‐S. Kim, J.‐W. Park, C.‐K. Park, J.‐H. Park & Y.‐J. Ko. (2021) Investigation of the optimal medium and application strategy for foot‐and‐mouth disease vaccine antigen production. Journal of Applied Microbiology 131:3, pages 1113-1122.
Crossref
Crossref
Sang-Hyun Park, Seo-Yong Lee, Jae-Seok Kim, Ah-Young Kim, Sun-Young Park, Ji-Hye Lee, Mijung Lee, Hyejin Kim, Sim-In Lee, Na-Young Kang, Jung-Won Park, Su-Mi Kim, Jong-Hyeon Park & Young-Joon Ko. (2021) Scale-Up Production of Type O and A Foot-and-Mouth Disease Bivalent Vaccine and Its Protective Efficacy in Pigs. Vaccines 9:6, pages 586.
Crossref
Crossref
Geoffri Ricci, Kevin Minsker, Austin Kapish, James Osborn, Sha Ha, Joseph Davide, Joseph P. Califano, Darrell Sehlin, Richard R. Rustandi, Lawrence W. DickJr.Jr., Josef Vlasak, Timothy D. Culp, Andreas Baudy, Edward Bell & Malini Mukherjee. (2021) Flow virometry for process monitoring of live virus vaccines-lessons learned from ERVEBO. Scientific Reports 11:1.
Crossref
Crossref
Roy Chih Chung Wang, David A. Campbell, James R. Green & Miroslava Čuperlović-Culf. (2021) Automatic 1D 1H NMR Metabolite Quantification for Bioreactor Monitoring. Metabolites 11:3, pages 157.
Crossref
Crossref
Mehdi Rahpeyma & Rouzbeh Bashar. (2021) Evaluation of Multiplicity of Infection (MOI) and Harvesting Time on the Production of CVS-11 Strain of Rabies Virus in BSR Cell Line. Journal of Medical Microbiology and Infectious Diseases 9:1, pages 25-31.
Crossref
Crossref
Gwendal Gränicher, Felipe Tapia, Ilona Behrendt, Ingo Jordan, Yvonne Genzel & Udo Reichl. (2020) Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector Production. Biotechnology Journal 16:1.
Crossref
Crossref
Jianlin Xu, Matthew S. Rehmann, Mengmeng Xu, Shun Zheng, Charles Hill, Qin He, Michael C. Borys & Zheng Jian Li. (2020) Development of an intensified fed-batch production platform with doubled titers using N-1 perfusion seed for cell culture manufacturing. Bioresources and Bioprocessing 7:1.
Crossref
Crossref
Jianqi Nie, Yang Sun, Feng Peng, Fei Han, Yankun Yang, Xiuxia Liu, Chunli Liu, Ye Li & Zhonghu Bai. (2020) Pseudorabies virus production using a serum-free medium in fixed-bed bioreactors with low cell inoculum density. Biotechnology Letters 42:12, pages 2551-2560.
Crossref
Crossref
Sascha Kiesslich & Amine A. Kamen. (2020) Vero cell upstream bioprocess development for the production of viral vectors and vaccines. Biotechnology Advances 44, pages 107608.
Crossref
Crossref
Alexander Nikolay, Joris de Grooth, Yvonne Genzel, Jeffery A. Wood & Udo Reichl. (2020) Virus harvesting in perfusion culture: Choosing the right type of hollow fiber membrane. Biotechnology and Bioengineering 117:10, pages 3040-3052.
Crossref
Crossref
Juliana Coronel, Gwendal Gränicher, Volker Sandig, Thomas Noll, Yvonne Genzel & Udo Reichl. (2020) Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion Mode. Frontiers in Bioengineering and Biotechnology 8.
Crossref
Crossref
Jianqi Nie, Yang Sun, Fei Han, Yankun Yang, Xiuxia Liu, Chunli Liu, Ye Li & Zhonghu Bai. (2020) Rapid process development of serum-free pseudorabies virus production with the Quality by Design approach. Cytotechnology 72:2, pages 283-293.
Crossref
Crossref
Jianqi Nie, Yang Sun, Feng Peng, Xinran Li, Yankun Yang, Xiuxia Liu, Ye Li, Chunli Liu & Zhonghu Bai. (2020) Production Process Development of Pseudorabies Virus Vaccine by Using a Novel Scale-Down Model of a Fixed-Bed Bioreactor. Journal of Pharmaceutical Sciences 109:2, pages 959-965.
Crossref
Crossref
Brahim Benyahia, Larissa Pereira Brumano, Adalberto Pessoa & Francisco Vitor Santos da Silva. 2020. New and Future Developments in Microbial Biotechnology and Bioengineering. New and Future Developments in Microbial Biotechnology and Bioengineering
31
68
.
Thirumeni Nagarajan & Hildegund C.J. Ertl. 2020. Rabies. Rabies
481
508
.
Alexander Nikolay, Thomas Bissinger, Gwendal Gränicher, Yixiao Wu, Yvonne Genzel & Udo Reichl. 2020. Animal Cell Biotechnology. Animal Cell Biotechnology
141
168
.
Tim Bürgin, Juliana Coronel, Gerrit Hagens, Michael V. Keebler, Yvonne Genzel, Udo Reichl & Tibor Anderlei. 2020. Animal Cell Biotechnology. Animal Cell Biotechnology
105
123
.
Jianjun Yang, Patrick Guertin, Guodong Jia, Zhongliang Lv, Hongyan Yang & Dianwen Ju. (2019) Large-scale microcarrier culture of HEK293T cells and Vero cells in single-use bioreactors. AMB Express 9:1.
Crossref
Crossref
Omar Khan & Chandra Mouli R. Madhuranthakam. (2019) Optimization of Robust Model Predictive Controllers for Second-Order Biological Processes Using Markov Chain Monte Carlo Techniques. Industrial & Engineering Chemistry Research 58:47, pages 21569-21583.
Crossref
Crossref
Marcos Sousa, Christel Fenge, Jens Rupprecht, Alexander Tappe, Gerhard Greller, Paula Alves, Manuel Carrondo & António Roldão. (2019) Process intensification for Peste des Petites Ruminants Virus vaccine production. Vaccine 37:47, pages 7041-7051.
Crossref
Crossref
Juliana Coronel, Ilona Behrendt, Tim Bürgin, Tibor Anderlei, Volker Sandig, Udo Reichl & Yvonne Genzel. (2019) Influenza A virus production in a single-use orbital shaken bioreactor with ATF or TFF perfusion systems. Vaccine 37:47, pages 7011-7018.
Crossref
Crossref
Samia Rourou, Meriem Ben Zakkour & Héla Kallel. (2019) Adaptation of Vero cells to suspension growth for rabies virus production in different serum free media. Vaccine 37:47, pages 6987-6995.
Crossref
Crossref
A. Raquel Fortuna, Sebastian van Teeffelen, Adrian Ley, Laura M. Fischer, Florian Taft, Yvonne Genzel, Louis Villain, Michael W. Wolff & Udo Reichl. (2019) Use of sulfated cellulose membrane adsorbers for chromatographic purification of cell cultured-derived influenza A and B viruses. Separation and Purification Technology 226, pages 350-358.
Crossref
Crossref
Kyle BurrellRkia DardariTaylor GoldsmithDerek TomsDaniel A.F. VillagomezWilliam Allan KingMark UngrinFranklin D. WestIna Dobrinski. (2019) Stirred Suspension Bioreactor Culture of Porcine Induced Pluripotent Stem Cells. Stem Cells and Development 28:18, pages 1264-1275.
Crossref
Crossref
Valentin Jossen, Regine Eibl & Dieter Eibl. 2019. Single‐Use Technology in Biopharmaceutical Manufacture. Single‐Use Technology in Biopharmaceutical Manufacture
37
52
.
Lea Pourchet, Emma Petiot, Céline Loubière, Eric Olmos, Morgan Dos Santos, Amélie Thépot, Blum J. Loïc & Christophe A. Marquette. (2019) Large 3D bioprinted tissue: Heterogeneous perfusion and vascularization. Bioprinting 13, pages e00039.
Crossref
Crossref
LeTuyen Nguyen, Sumi Bang & Insup Noh. (2019) Tissue Regeneration of Human Mesenchymal Stem Cells on Porous Gelatin Micro-Carriers by Long-Term Dynamic In Vitro Culture. Tissue Engineering and Regenerative Medicine 16:1, pages 19-28.
Crossref
Crossref
Zoltán Kis, Robin Shattock, Nilay Shah & Cleo Kontoravdi. (2018) Emerging Technologies for Low‐Cost, Rapid Vaccine Manufacture. Biotechnology Journal 14:1.
Crossref
Crossref
Anne F. Pihl, Anna F. Offersgaard, Christian K. Mathiesen, Jannick Prentoe, Ulrik Fahnøe, Henrik Krarup, Jens Bukh & Judith M. Gottwein. (2018) High density Huh7.5 cell hollow fiber bioreactor culture for high-yield production of hepatitis C virus and studies of antivirals. Scientific Reports 8:1.
Crossref
Crossref
Omar Khan, Chandra Mouli R. Madhuranthakam, Peter Douglas, Heron Lau, Jacob Sun & Patrick Farrell. (2018) Optimized PID controller for an industrial biological fermentation process. Journal of Process Control 71, pages 75-89.
Crossref
Crossref
Alexander Nikolay, Arnaud Léon, Klaus Schwamborn, Yvonne Genzel & Udo Reichl. (2018) Process intensification of EB66® cell cultivations leads to high-yield yellow fever and Zika virus production. Applied Microbiology and Biotechnology 102:20, pages 8725-8737.
Crossref
Crossref
Mousumi Bora, Raja Wasim Yousuf, Pronab Dhar & Rabindra Prasad Singh. (2018) An overview of process intensification and thermo stabilization for upscaling of Peste des petits ruminants vaccines in view of global control and eradication. VirusDisease 29:3, pages 285-296.
Crossref
Crossref
Alexander Nikolay, Leda R. Castilho, Udo Reichl & Yvonne Genzel. (2018) Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells. Vaccine 36:22, pages 3140-3145.
Crossref
Crossref
Chia-Chyi Liu, Suh-Chin Wu, Shang-Rung Wu, Hsiao-Yu Lin, Meng-Shin Guo, Alan Yung-Chih Hu, Yen-Hung Chow, Jen-Ron Chiang, Dar-Bin Shieh & Pele Chong. (2018) Enhancing enterovirus A71 vaccine production yield by microcarrier profusion bioreactor culture. Vaccine 36:22, pages 3134-3139.
Crossref
Crossref
Nagesh K. Tripathi & Ambuj Shrivastava. 2018. Nanoscale Fabrication, Optimization, Scale-Up and Biological Aspects of Pharmaceutical Nanotechnology. Nanoscale Fabrication, Optimization, Scale-Up and Biological Aspects of Pharmaceutical Nanotechnology
133
172
.
Hari Pujar & Mats Lundgren. 2018. Biopharmaceutical Processing. Biopharmaceutical Processing
877
898
.
Shannon Eaker, Eytan Abraham, Julie Allickson, Thomas A. Brieva, Dolores Baksh, Thomas R.J. Heathman, Biren Mistry & Nan Zhang. (2017) Bioreactors for cell therapies: Current status and future advances. Cytotherapy 19:1, pages 9-18.
Crossref
Crossref
Felipe Tapia, Daniel Vázquez-Ramírez, Yvonne Genzel & Udo Reichl. (2016) Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production. Applied Microbiology and Biotechnology 100:5, pages 2121-2132.
Crossref
Crossref