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Vaccine Profile

Pollinex® Quattro: a novel and well–tolerated, ultra short–course allergy vaccine

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Pages 617-629 | Published online: 09 Jan 2014

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Read on this site (8)

Lara Šošić, Marta Paolucci, Stephan Flory, Fadi Jebbawi, Thomas M. Kündig & Pål Johansen. (2023) Allergen immunotherapy: progress and future outlook. Expert Review of Clinical Immunology 19:7, pages 745-769.
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Marco Caminati, Anna Rita Dama, Ivana Djuric, Marcello Montagni, Michele Schiappoli, Erminia Ridolo, Gianenrico Senna & Giorgio Walter Canonica. (2015) Incidence and risk factors for subcutaneous immunotherapy anaphylaxis: the optimization of safety. Expert Review of Clinical Immunology 11:2, pages 233-245.
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Martin Rosewich, Denise Lee & Stefan Zielen. (2013) Pollinex Quattro: An innovative four injections immunotherapy In allergic rhinitis. Human Vaccines & Immunotherapeutics 9:7, pages 1523-1531.
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Shaherin Basith, Balachandran Manavalan, Gwang Lee, Sang Geon Kim & Sangdun Choi. (2011) Toll-like receptor modulators: a patent review (2006 – 2010). Expert Opinion on Therapeutic Patents 21:6, pages 927-944.
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Antu K Dey & Indresh K Srivastava. (2011) Novel adjuvants and delivery systems for enhancing immune responses induced by immunogens. Expert Review of Vaccines 10:2, pages 227-251.
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Linda Cox & Moises A. Calderon. (2010) Subcutaneous specific immunotherapy for seasonal allergic rhinitis: a review of treatment practices in the US and Europe. Current Medical Research and Opinion 26:12, pages 2723-2733.
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Sandra M Gawchik & Consuelo L Saccar. (2009) Pollinex Quattro Tree: allergy vaccine. Expert Opinion on Biological Therapy 9:3, pages 377-382.
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Reto Crameri. (2007) Allergy vaccines: dreams and reality. Expert Review of Vaccines 6:6, pages 991-999.
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Articles from other publishers (39)

Jonaid Ahmad Malik, Gurpreet Kaur & Javed N. Agrewala. (2023) Revolutionizing medicine with toll-like receptors: A path to strengthening cellular immunity. International Journal of Biological Macromolecules 253, pages 127252.
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Scott Fiala & Howard B Fleit. (2023) Clinical and experimental treatment of allergic asthma with an emphasis on allergen immunotherapy and its mechanisms. Clinical and Experimental Immunology 212:1, pages 14-28.
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Fabiana Furci, Marco Caminati, Ernesto Crisafulli, Gianenrico Senna & Sebastiano Gangemi. (2023) The intriguing possibility of using probiotics in allergen-specific immunotherapy. World Allergy Organization Journal 16:2, pages 100751.
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Jennifer Zimmermann, Alexandra Goretzki, Clara Meier, Sonja Wolfheimer, Yen-Ju Lin, Hannah Rainer, Maren Krause, Saskia Wedel, Gerd Spies, Frank Führer, Stefan Vieths, Stephan Scheurer & Stefan Schülke. (2022) Modulation of dendritic cell metabolism by an MPLA-adjuvanted allergen product for specific immunotherapy. Frontiers in Immunology 13.
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Despo Chatzikleanthous, Derek T. O’Hagan & Roberto Adamo. (2021) Lipid-Based Nanoparticles for Delivery of Vaccine Adjuvants and Antigens: Toward Multicomponent Vaccines. Molecular Pharmaceutics 18:8, pages 2867-2888.
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Paxton Loke, Adriana Chebar Lozinsky, Francesca Orsini, Lydia Su-Yin Wong, Agnes Sze-Yin Leung, Elizabeth Huiwen Tham, Andreas L Lopata, Lynette Pei-Chi Shek & Mimi LK Tang. (2021) Study protocol of a phase 2, dual-centre, randomised, controlled trial evaluating the effectiveness of probiotic and egg oral immunotherapy at inducing desensitisation or sustained unresponsiveness (remission) in participants with egg allergy compared with placebo (Probiotic Egg Allergen Oral Immunotherapy for Treatment of Egg Allergy: PEAT study). BMJ Open 11:7, pages e044331.
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Beatriz León & Andre Ballesteros-Tato. (2021) Modulating Th2 Cell Immunity for the Treatment of Asthma. Frontiers in Immunology 12.
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Marina Luchner, Sören Reinke & Anita Milicic. (2021) TLR Agonists as Vaccine Adjuvants Targeting Cancer and Infectious Diseases. Pharmaceutics 13:2, pages 142.
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José Fernando Florido-López, Carmen Andreu-Balaguer, Carmelo Escudero, Marta Seoane-Rodríguez, Mercedes Hernández, Luis Ángel Navarro-Seisdedos, Miguel Torrecillas-Toro, Mónica Anton-Girones, Leticia Herrero-Lifona, Dorimar Brugaletta, Jesús Macías, Rafael Pineda, Maria Ángeles Lara, Julián López-Caballero & Maria José Rojas. (2020) Effectiveness and safety of a glutaraldehyde-modified, L-tyrosine-adsorbed and monophosphoryl lipid A-Adjuvanted allergen immunotherapy in patients with allergic asthma sensitized to olive pollen: A retrospective, controlled real-world study. World Allergy Organization Journal 13:12, pages 100487.
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Sahra Bashiri, Prashamsa Koirala, Istvan Toth & Mariusz Skwarczynski. (2020) Carbohydrate Immune Adjuvants in Subunit Vaccines. Pharmaceutics 12:10, pages 965.
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Litty Johnson, Albert Duschl & Martin Himly. (2020) Nanotechnology-Based Vaccines for Allergen-Specific Immunotherapy: Potentials and Challenges of Conventional and Novel Adjuvants under Research. Vaccines 8:2, pages 237.
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Patrick Rizk, Mario Rodenas & Anna De Benedetto. (2019) Allergen Immunotherapy and Atopic Dermatitis: the Good, the Bad, and the Unknown. Current Allergy and Asthma Reports 19:12.
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Frank Blanco-Pérez, Alexandra Goretzki, Sonja Wolfheimer & Stefan Schülke. (2019) The vaccine adjuvant MPLA activates glycolytic metabolism in mouse mDC by a JNK-dependent activation of mTOR-signaling. Molecular Immunology 106, pages 159-169.
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Natasha C. Gunawardana & Stephen R. Durham. (2018) New approaches to allergen immunotherapy. Annals of Allergy, Asthma & Immunology 121:3, pages 293-305.
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O Pfaar, U Pieper-Fürst & R Mösges. (2018) Ultra-short-course booster allergen immunotherapy. Immunotherapy 10:7, pages 525-528.
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O. Pfaar, S. Lang, U. Pieper‐Fürst, A. Astvatsatourov, F. Gerich, L. Klimek, M. F. Kramer, Y. Reydelet, K. Shah‐Hosseini & R. Mösges. (2017) Ultra‐short‐course booster is effective in recurrent grass pollen‐induced allergic rhinoconjunctivitis. Allergy 73:1, pages 187-195.
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Stefan Schülke, Lothar Vogel, Ann-Christine Junker, Kay-Martin Hanschmann, Adam Flaczyk, Stefan Vieths & Stephan Scheurer. (2016) A Fusion Protein Consisting of the Vaccine Adjuvant Monophosphoryl Lipid A and the Allergen Ovalbumin Boosts Allergen-Specific Th1, Th2, and Th17 Responses In Vitro . Journal of Immunology Research 2016, pages 1-8.
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Kai Schulze, Thomas Ebensen, Peggy Riese, Blair Prochnow, Claus-Michael Lehr & Carlos A. Guzmán. 2016. How to Overcome the Antibiotic Crisis. How to Overcome the Antibiotic Crisis 207 234 .
S. Schülke, A. Flaczyk, L. Vogel, N. Gaudenzio, I. Angers, B. Löschner, S. Wolfheimer, I. Spreitzer, S. Qureshi, M. Tsai, S. Galli, S. Vieths & S. Scheurer. (2015) MPLA shows attenuated pro-inflammatory properties and diminished capacity to activate mast cells in comparison with LPS. Allergy 70:10, pages 1259-1268.
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Ekaterini Tiligada, Masaru Ishii, Carlo Riccardi, Michael Spedding, Hans-Uwe Simon, Mauro Martins Teixeira, Mario Landys Chovel Cuervo, Stephen T Holgate & Francesca Levi-Schaffer. (2015) The expanding role of immunopharmacology: IUPHAR Review 16. British Journal of Pharmacology 172:17, pages 4217-4227.
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Michelle L. North, Mena Soliman, Terry Walker, Lisa M. Steacy & Anne K. Ellis. (2015) Controlled Allergen Challenge Facilities and Their Unique Contributions to Allergic Rhinitis Research. Current Allergy and Asthma Reports 15:4.
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Deborah A. Garside, Reinaldo Acevedo, Manal Alsaadi, Natalie Nimmo, Ayman Gebril, Dimitrios Lamprou, Alexander B. Mullen & Valerie A. Ferro. 2015. Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies. Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies 221 250 .
Piyush Patel, Tom Holdich, Karl J. Fischer von Weikersthal-Drachenberg & Birgit Huber. (2014) Efficacy of a short course of specific immunotherapy in patients with allergic rhinoconjunctivitis to ragweed pollen. Journal of Allergy and Clinical Immunology 133:1, pages 121-129.e2.
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Anne K. Ellis, Michelle L. North, Terry Walker & Lisa M. Steacy. (2013) Environmental exposure unit: a sensitive, specific, and reproducible methodology for allergen challenge. Annals of Allergy, Asthma & Immunology 111:5, pages 323-328.
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Giuseppe Mastrangelo, Emanuela Fadda & Luca Cegolon. (2013) Endotoxin and cancer chemo-prevention. Cancer Epidemiology 37:5, pages 528-533.
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Nicola Scichilone, Vincenza Scalici, Rita Arrigo & Vincenzo Bellia. (2013) Clinical and anti-inflammatory effects of ultra-short preseasonal vaccine to Parietaria in asthma . Therapeutic Advances in Respiratory Disease 7:4, pages 207-215.
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Mona Hedayat, Kiyoshi Takeda & Nima Rezaei. (2010) Prophylactic and therapeutic implications of toll‐like receptor ligands. Medicinal Research Reviews 32:2, pages 294-325.
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J. Ring & J. Gutermuth. (2011) 100 years of hyposensitization: history of allergen-specific immunotherapy (ASIT). Allergy 66:6, pages 713-724.
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Tunc AkkocMübeccel AkdisCezmi A. Akdis. (2011) Update in the Mechanisms of Allergen-Specific Immunotheraphy. Allergy, Asthma and Immunology Research 3:1, pages 11.
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Soo-Kweon Koo. (2010) Current Update of Pediatric Allergic Rhinitis. Journal of Clinical Otolaryngology Head and Neck Surgery 21:1, pages 33-40.
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Martin Rosewich. (2010) Ultra-short course immunotherapy in children and adolescents during a 3-yrs post-marketing surveillance study. Pediatric Allergy and Immunology 21:1-Part-II, pages e185-e189.
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Olga Borges, Filipa Lebre, Dulce Bento, Gerrit Borchard & Hans E. Junginger. (2009) Mucosal Vaccines: Recent Progress in Understanding the Natural Barriers. Pharmaceutical Research 27:2, pages 211-223.
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Ol'ga Valer'evna Trusova, I M Gayduk, D S Korostovtsev, О V Trusova, I M Gaiduk & D S Korostovtsev. (2009) Allergen-specific immunotherapy in children, and the perspectives of the method. Russian Journal of Allergy 6:4, pages 58-66.
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Mübeccel Akdis & Cezmi A. Akdis. (2009) Therapeutic manipulation of immune tolerance in allergic disease. Nature Reviews Drug Discovery 8:8, pages 645-660.
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Jennifer M. Rolland, Leanne M. Gardner & Robyn E. O'Hehir. (2009) Allergen-related approaches to immunotherapy. Pharmacology & Therapeutics 121:3, pages 273-284.
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Dragana Stanic, Lidija Burazer, Marija Gavrovic-Jankulovic, Ratko JankovM.M. & Tanja Cirkovic-Velickovic. (2009) Chemical modification of Art v 1, a major mugwort pollen allergen, by cis-aconitylation and citraconylation. Journal of the Serbian Chemical Society 74:4, pages 359-366.
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