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Review

Clinical utilization of chemokines to combat cancer: the double-edged sword

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Pages 267-283 | Published online: 09 Jan 2014

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Lorenzo Pilla, Soldano Ferrone & Cristina Maccalli. (2018) Methods for improving the immunogenicity and efficacy of cancer vaccines. Expert Opinion on Biological Therapy 18:7, pages 765-784.
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Karin Jöhrer, Lisa Pleyer, Angelika Olivier, Eva Maizner, Claudia Zelle-Rieser & Richard Greil. (2008) Tumour-immune cell interactions modulated by chemokines. Expert Opinion on Biological Therapy 8:3, pages 269-290.
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M. Merle, D. Fischbacher, A. Liepert, C. Grabrucker, T. Kroell, A. Kremser, J. Dreyssig, M. Freudenreich, F. Schuster, A. Borkhardt, D. Kraemer, C.-H. Koehne, H.J. Kolb, C. Schmid & H.M. Schmetzer. (2021) Conversion of AML-blasts to leukemia-derived dendritic cells (DCleu) in ‘DC-culture-media’ shifts correlations of released chemokines with antileukemic T-cell reactions. Immunobiology 226:3, pages 152088.
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Deepa Bedi, Henry Henderson, Upender Manne & Temesgen Samuel. (2019) Camptothecin Induces PD-L1 and Immunomodulatory Cytokines in Colon Cancer Cells. Medicines 6:2, pages 51.
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Cristina Maccalli. 2019. Cancer Stem Cell Resistance to Targeted Therapy. Cancer Stem Cell Resistance to Targeted Therapy 137 151 .
Minkyo Song, Shizuka Sasazuki, M. Constanza Camargo, Taichi Shimazu, Hadrien Charvat, Taiki Yamaji, Norie Sawada, Troy J. Kemp, Ruth M. Pfeiffer, Allan Hildesheim, Ligia A. Pinto, Charles S. Rabkin & Shoichiro Tsugane. (2018) Circulating inflammatory markers and colorectal cancer risk: A prospective case-cohort study in Japan. International Journal of Cancer 143:11, pages 2767-2776.
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Tomonobu Koizumi, Vivek Shetty & Masaki Yamaguchi. (2018) Salivary cytokine panel indicative of non-small cell lung cancer. Journal of International Medical Research 46:9, pages 3570-3582.
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Mayela Mendt & Jose E. Cardier. (2017) Activation of the CXCR4 chemokine receptor enhances biological functions associated with B16 melanoma liver metastasis. Melanoma Research 27:4, pages 300-308.
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Joshua J. Ziarek, Andrew B. Kleist, Nir LondonBarak RavehNicolas Montpas, Julien BonneterreGeneviève St-OngeCrystal J. DiCosmo-Ponticello, Chad A. KoplinskiIshan RoyBryan StephensSylvia ThelenChristopher T. VeldkampFrederick D. CoffmanMarion C. Cohen, Michael B. DwinellMarcus ThelenFrancis C. Peterson, Nikolaus HevekerBrian F. Volkman. (2017) Structural basis for chemokine recognition by a G protein–coupled receptor and implications for receptor activation. Science Signaling 10:471.
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Sébastien Tabariès, Véronique Ouellet, Brian E Hsu, Matthew G Annis, April AN Rose, Liliane Meunier, Euridice Carmona, Christine E Tam, Anne-Marie Mes-Masson & Peter M Siegel. (2015) Granulocytic immune infiltrates are essential for the efficient formation of breast cancer liver metastases. Breast Cancer Research 17:1.
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Wei Ting Chang, Tzung Hsien Lai, Yau Jan Chyan, Shu Yi Yin, Yung Hsiang Chen, Wen Chi Wei & Ning-Sun Yang. (2015) Specific Medicinal Plant Polysaccharides Effectively Enhance the Potency of a DC-Based Vaccine against Mouse Mammary Tumor Metastasis. PLOS ONE 10:3, pages e0122374.
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Takahiko Hara & Kosuke Tanegashima. (2014) CXCL14 antagonizes the CXCL12-CXCR4 signaling axis. Biomolecular Concepts 5:2, pages 167-173.
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John A. Puskas, Yohsuke Yagawa & James J. Mulé. 2014. Gene Therapy of Cancer. Gene Therapy of Cancer 301 314 .
Tomonori Takekoshi, Xuesong Wu, Hiroshi Mitsui, Yayoi Tada, Mandy C. Kao, Shinichi Sato, Michael B. Dwinell & Sam T. Hwang. (2013) CXCR4 Negatively Regulates Keratinocyte Proliferation in IL-23-Mediated Psoriasiform Dermatitis. Journal of Investigative Dermatology 133:11, pages 2530-2537.
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Iuliana Bobanga, Agne Petrosiute & Alex Huang. (2013) Chemokines as Cancer Vaccine Adjuvants. Vaccines 1:4, pages 444-462.
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Katarzyna Franciszkiewicz, Alexandre Boissonnas, Marie Boutet, Christophe Combadière & Fathia Mami-Chouaib. (2012) Role of Chemokines and Chemokine Receptors in Shaping the Effector Phase of the Antitumor Immune Response. Cancer Research 72:24, pages 6325-6332.
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T Nguyen-Hoai, O Hohn, M D Vu, G Baldenhofer, M S Sayed Ahmed, B Dörken, S Norley, M Lipp, A Pezzutto & J Westermann. (2012) CCL19 as an adjuvant for intradermal gene gun immunization in a Her2/neu mouse tumor model: improved vaccine efficacy and a role for B cells as APC. Cancer Gene Therapy 19:12, pages 880-887.
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Tomonori Takekoshi, Joshua J. Ziarek, Brian F. Volkman & Sam T. Hwang. (2012) A Locked, Dimeric CXCL12 Variant Effectively Inhibits Pulmonary Metastasis of CXCR4-Expressing Melanoma Cells Due to Enhanced Serum Stability. Molecular Cancer Therapeutics 11:11, pages 2516-2525.
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Elham Mohit & Sima Rafati. (2012) Chemokine-based immunotherapy: delivery systems and combination therapies. Immunotherapy 4:8, pages 807-840.
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Evangelia Razis, Konstantine T. Kalogeras, Vassiliki Kotoula, Anastasia G. Eleftheraki, Nikitas Nikitas, Ralf Kronenwett, Eleni Timotheadou, Christos Christodoulou, Dimitrios Pectasides, Helen Gogas, Ralph M. Wirtz, Thomas Makatsoris, Dimitrios Bafaloukos, Gerasimos Aravantinos, Despina Televantou, Nicholas Pavlidis & George Fountzilas. (2012) Improved Outcome of High-Risk Early HER2 Positive Breast Cancer With High CXCL13-CXCR5 Messenger RNA Expression. Clinical Breast Cancer 12:3, pages 183-193.
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Tam Nguyen‐Hoai, Gerd Baldenhofer, Mona Sayed Ahmed, Minh Pham‐Duc, Margarete Gries, Martin Lipp, Bernd Dörken, Antonio Pezzutto & Jörg Westermann. (2012) CCL19 (ELC) improves TH1‐polarized immune responses and protective immunity in a murine Her2/neu DNA vaccination model. The Journal of Gene Medicine 14:2, pages 128-137.
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T Nguyen-Hoai, G Baldenhofer, M S Sayed Ahmed, M Pham-Duc, M D Vu, M Lipp, B Dörken, A Pezzutto & J Westermann. (2011) CCL21 (SLC) improves tumor protection by a DNA vaccine in a Her2/neu mouse tumor model. Cancer Gene Therapy 19:1, pages 69-76.
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Noriho Iida, Yasunari Nakamoto, Tomohisa Baba, Hidetoshi Nakagawa, Eishiro Mizukoshi, Makoto Naito, Naofumi Mukaida & Shuichi Kaneko. (2010) Antitumor Effect after Radiofrequency Ablation of Murine Hepatoma Is Augmented by an Active Variant of CC Chemokine Ligand 3/Macrophage Inflammatory Protein-1α. Cancer Research 70:16, pages 6556-6565.
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